Filters








713 Hits in 2.0 sec

Symmetry breaking during homodimeric assembly activates an E3 ubiquitin ligase

Zhaofeng Ye, Patrick G. Needham, Samuel K. Estabrooks, Susan K. Whitaker, Brandon L. Garcia, Saurav Misra, Jeffrey L. Brodsky, Carlos J. Camacho
<span title="2017-05-11">2017</span> <i title="Springer Nature"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/tnqhc2x2aneavcd3gx5h7mswhm" style="color: black;">Scientific Reports</a> </i> &nbsp;
The most prominent CHIP autoubiquitination site is K 2 29, 30 , located within a flexible ~25-residue N-terminal segment of CHIP.  ...  Our modeling suggests that K 2 of the straight (active) protomer is the only lysine that can readily access the active site of a bound E2 enzyme (not shown).  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1038/s41598-017-01880-4">doi:10.1038/s41598-017-01880-4</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/28496195">pmid:28496195</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC5431976/">pmcid:PMC5431976</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/qtbcnb2x5jbndmq46ecgtvn4ku">fatcat:qtbcnb2x5jbndmq46ecgtvn4ku</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200210172525/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC5431976&amp;blobtype=pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/d2/8e/d28ee96860fb3ad9b630bd0a5943b55a40b271c7.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1038/s41598-017-01880-4"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431976" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Predicting protein targets for drug-like compounds using transcriptomics [article]

Nicolas A Pabon, Yan Xia, Samuel K. Estabrooks, Zhaofeng Ye, Amanda K. Herbrand, Evelyn Sub, Ricardo M. Biondi, Victoria A. Assimon, Jason E. Gestwicki, Jeffrey L. Brodsky, Carlos J. Camacho, Ziv Bar-Joseph
<span title="2018-01-25">2018</span> <i title="Cold Spring Harbor Laboratory"> bioRxiv </i> &nbsp; <span class="release-stage" >pre-print</span>
Of note, differential expression of genes functionally related to K/HRAS, i.e. FGFR4, FGFR2, FRS1, inform on novel regulatory phenotypes responding to both compound inhibition and gene knock out.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1101/254367">doi:10.1101/254367</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/52ovirk3j5cflg54c4z6lcrsau">fatcat:52ovirk3j5cflg54c4z6lcrsau</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20190501232944/https://www.biorxiv.org/content/biorxiv/early/2018/03/09/254367.full.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/9a/36/9a36d0f93cc712f4f318ab438f6dc7e753ceaba7.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1101/254367"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> biorxiv.org </button> </a>

Predicting protein targets for drug-like compounds using transcriptomics

Nicolas A. Pabon, Yan Xia, Samuel K. Estabrooks, Zhaofeng Ye, Amanda K. Herbrand, Evelyn Süß, Ricardo M. Biondi, Victoria A. Assimon, Jason E. Gestwicki, Jeffrey L. Brodsky, Carlos J. Camacho, Ziv Bar-Joseph (+1 others)
<span title="2018-12-07">2018</span> <i title="Public Library of Science (PLoS)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/ch57atmlprauhhbqdf7x4ytejm" style="color: black;">PLoS Computational Biology</a> </i> &nbsp;
Of note, differential expression of genes functionally related to K/HRAS, i.e. FGFR4, FGFR2, FRS1, inform on novel regulatory phenotypes responding to both compound inhibition and gene knock out.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1371/journal.pcbi.1006651">doi:10.1371/journal.pcbi.1006651</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/30532261">pmid:30532261</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC6300300/">pmcid:PMC6300300</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/r56vl7x3tjcerpebjdxfft3nze">fatcat:r56vl7x3tjcerpebjdxfft3nze</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20190223154100/http://pdfs.semanticscholar.org/4932/c0731068e4c220df8e6c37d5ff58a6de516e.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/49/32/4932c0731068e4c220df8e6c37d5ff58a6de516e.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1371/journal.pcbi.1006651"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> plos.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300300" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Page 599 of American Economic Association Quarterly Vol. 2, Issue 2 [page]

<span title="">1901</span> <i title="Open Court Publishing Co"> <a target="_blank" rel="noopener" href="https://archive.org/details/pub_american-economic-association-quarterly" style="color: black;">American Economic Association Quarterly </a> </i> &nbsp;
A, B, K, N, S. | | Joseph, Wenham. A, R. Timothy. A. DEAN. Ichabod, Taunton. A, N, O, S. Samuel, Dedham. A, I,N, O, S. DEATH. Oliver, Framingham. A, B, D, N, 0, S$ DELINO, DELANO, DELANA. Jonathan.  ...  EASTABROOKE, EASTERBROOKS, ESTABROOK. Benjamin, Sudbury. A, B, D, N, O, Ss. ’ O, S. EASTERBROOK, ESTABROOKS,  ... 
<span class="external-identifiers"> </span>
<a target="_blank" rel="noopener" href="https://archive.org/details/sim_american-economic-association-quarterly_1901-05_2_2/page/599" title="read fulltext microfilm" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Archive [Microfilm] <div class="menu fulltext-thumbnail"> <img src="https://archive.org/serve/sim_american-economic-association-quarterly_1901-05_2_2/__ia_thumb.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a>

Page 713 of MH: Mental Hygiene Vol. 28, Issue 4 [page]

<span title="">1944</span> <i title="National Mental Health Association"> <a target="_blank" rel="noopener" href="https://archive.org/details/pub_mh-mental-hygiene" style="color: black;">MH: Mental Hygiene </a> </i> &nbsp;
Kiser, Louise K., see Frank, Law- rence K, Kraines, Samuel H. The therapy of the neuroses and psychoses. 2d ed. Rev. by O. Spurgeon English, 496-97. Kunkel, Fritz. In search of maturity.  ...  England, Mary R., see Bender, Irving E Estabrooks, George H. Hypnotism. Rev. by Milton H. Erickson, 491-95. Estabrooks, George H. mechanical misfit. Neumann, 486-87. Foster, Robert G. and Wilson, P.  ... 
<span class="external-identifiers"> </span>
<a target="_blank" rel="noopener" href="https://archive.org/details/sim_mh-mental-hygiene_1944-10_28_4/page/713" title="read fulltext microfilm" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Archive [Microfilm] <div class="menu fulltext-thumbnail"> <img src="https://archive.org/serve/sim_mh-mental-hygiene_1944-10_28_4/__ia_thumb.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a>

Page 20 of Academy of Political Science. Proceedings of the Academy of Political Science Vol. 3, Issue [page]

<span title="">1912</span> <i title="Academy of Political Science"> <a target="_blank" rel="noopener" href="https://archive.org/details/pub_academy-of-political-science-proceedings" style="color: black;">Academy of Political Science. Proceedings of the Academy of Political Science </a> </i> &nbsp;
III Erb, Newman 42 Broadway Erbsloh, R. 564 Broadway Erdmann, Albert J. 30 Broad Street Essing, Arthur 44 West gist Street Estabrook, A. F. 15 State Street, Boston, Mass. Estabrook, H.  ...  Fairchild, Charles S. 35 Fifth Avenue Fairchild, Samuel W. P. O. Box 1120 Fairlie, John A. 1004 South Lincoln Avenue, Urbana, IIl. Fallows, Edward H. 30 Church Street Fancher, B.  ... 
<span class="external-identifiers"> </span>
<a target="_blank" rel="noopener" href="https://archive.org/details/sim_academy-of-political-science-proceedings_1912-1913_3/page/20" title="read fulltext microfilm" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Archive [Microfilm] <div class="menu fulltext-thumbnail"> <img src="https://archive.org/serve/sim_academy-of-political-science-proceedings_1912-1913_3/__ia_thumb.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a>

Page 320 of Water Environment Research Vol. 33, Issue 3 [page]

<span title="">1961</span> <i title="Water Environment Federation"> <a target="_blank" rel="noopener" href="https://archive.org/details/pub_water-environment-research" style="color: black;">Water Environment Research </a> </i> &nbsp;
K ordyce, H \ A ors, S.  ...  ., Fla Eschlim: John Ralph | Yellow rings, O Estabrook, Herbert I Sewage Trt. Plt M House f Correcti Rd., Billerica, Ma Estep, Raymond, A age Trt.  ... 
<span class="external-identifiers"> </span>
<a target="_blank" rel="noopener" href="https://archive.org/details/sim_water-environment-research_1961-03_33_3/page/320" title="read fulltext microfilm" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Archive [Microfilm] <div class="menu fulltext-thumbnail"> <img src="https://archive.org/serve/sim_water-environment-research_1961-03_33_3/__ia_thumb.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a>

Page 138 of Congregational Quarterly Vol. 17, Issue 1 [page]

<span title="">1875</span> <i title="Open Court Publishing Co"> <a target="_blank" rel="noopener" href="https://archive.org/details/pub_congregational-quarterly" style="color: black;">Congregational Quarterly </a> </i> &nbsp;
Estabrook, a.p, °52 1860/M.Q. McFarland, a.p. 43 1843) K. Wood worth, a.p. 1868 James Watts, a.p. 57 1863,C. N.  ...  Royal Oak, oe | TOTAL. ry | Deaths wocerwoc o |Dism. coscosct oc SocooocOocHOoScoScSSooScSe Soocoo o |/Excom Samuel Porter, a.p. 765 Salem, 1 Spray A Gelston, Pres. Sandstone, uewis M.  ... 
<span class="external-identifiers"> </span>
<a target="_blank" rel="noopener" href="https://archive.org/details/sim_congregational-quarterly_1875-01_17_1/page/138" title="read fulltext microfilm" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Archive [Microfilm] <div class="menu fulltext-thumbnail"> <img src="https://archive.org/serve/sim_congregational-quarterly_1875-01_17_1/__ia_thumb.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a>

Page 434 of AAPG Bulletin Vol. 11, Issue 4 [page]

<span title="">1927</span> <i title="American Association of Petroleum"> <a target="_blank" rel="noopener" href="https://archive.org/details/pub_american-association-of-petroleum-geologists-aapg" style="color: black;">AAPG Bulletin </a> </i> &nbsp;
Estabrook, Ellis A. Hall Ira Edward Dugan, Ponca City, Okla. Glenn C. Clark, Stuart K. Clark, W. A. J. M. van der Gracht Robert McNeely, Ponca City, Okla. C. L. Arnett, Glenn C. Clark, Stuart K.  ...  Stuart K. Clark, C. L. Arnett, Glenn C. Clark Joe Bernard Lovejoy, Wichita Falls, Tex. H. B. Fuqua, C. E. Yager, David Donoghue James Paul McKee, Ardmore, Okla. Samuel H. Woods, A. W. Lauer, John N.  ... 
<span class="external-identifiers"> </span>
<a target="_blank" rel="noopener" href="https://archive.org/details/sim_american-association-of-petroleum-geologists-aapg_1927-04_11_4/page/434" title="read fulltext microfilm" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Archive [Microfilm] <div class="menu fulltext-thumbnail"> <img src="https://archive.org/serve/sim_american-association-of-petroleum-geologists-aapg_1927-04_11_4/__ia_thumb.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a>

Page 840 of The New England Quarterly Vol. 10, Issue 4 [page]

<span title="">1937</span> <i title="New England Quarterly, Incorporated"> <a target="_blank" rel="noopener" href="https://archive.org/details/pub_new-england-quarterly" style="color: black;">The New England Quarterly </a> </i> &nbsp;
Drew, 1, 346- 355- A Letter from Samuel Mather of Witney, edited by Thomas H. Johnson, m1, 548-552. Lord Saye and Sele, by Charles K. Bolton, "1, 345-346. New Light on Lowell as Editor, by Edward G.  ...  Stearns, I, 557-583- Emerson and Communism, by George K. Smart, Iv, 772~-773- The Flight of Henry James the First, by Harold A.  ... 
<span class="external-identifiers"> </span>
<a target="_blank" rel="noopener" href="https://archive.org/details/sim_new-england-quarterly_1937-12_10_4/page/840" title="read fulltext microfilm" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Archive [Microfilm] <div class="menu fulltext-thumbnail"> <img src="https://archive.org/serve/sim_new-england-quarterly_1937-12_10_4/__ia_thumb.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a>

Page 48 of American Spirit Vol. 75, Issue 5 [page]

<span title="">1941</span> <i title="National Society of the Daughters"> <a target="_blank" rel="noopener" href="https://archive.org/details/pub_american-spirit" style="color: black;">American Spirit </a> </i> &nbsp;
Jewett, Nathaniel JouNsoNn, Samuel. JONES, Jones, Nathan..........N. K KAUFMAN, George KEATING, KEENE, | Ke.ter, Samuel......... N. KILBOURN, ae ht .Conn. 0 ree Md. ee Ga. Edmund aoe wie . Mass.  ...  EASTER, Eppy, ELGIN, EMERSON, EMISON, ESTABROOKS, Joseph... . EVERETT, F Fann, James......... FERGUSON, Samuel FIELD, Dennis......... Forses, Jehiel Forp, Foster, Frost, Joshua.  ... 
<span class="external-identifiers"> </span>
<a target="_blank" rel="noopener" href="https://archive.org/details/sim_american-spirit_1941-05_75_5/page/48" title="read fulltext microfilm" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Archive [Microfilm] <div class="menu fulltext-thumbnail"> <img src="https://archive.org/serve/sim_american-spirit_1941-05_75_5/__ia_thumb.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a>

Page 189 of Congregational Quarterly Vol. 13, Issue 1 [page]

<span title="">1871</span> <i title="Open Court Publishing Co"> <a target="_blank" rel="noopener" href="https://archive.org/details/pub_congregational-quarterly" style="color: black;">Congregational Quarterly </a> </i> &nbsp;
Ferris, Leonard Z., Lawrence, Mass, Fessenden, Samuel C., Washington, D.C. Fessenden, Thomas K., Farmington, Ct. Field, Artemas C., Alstead Centre, N. H. Field, George W., Bangor, Me.  ...  Evans, Samuel E., East Providence, R. I. Evans, Thomas, Palmyra, O. Evarts, Nathaniel K., Codyville, Mich. Everdell, Robert, Murone, Wis. Everts, Reuben, Amboy, Iil. Everest, Charles H., Brooklyn, N.  ... 
<span class="external-identifiers"> </span>
<a target="_blank" rel="noopener" href="https://archive.org/details/sim_congregational-quarterly_1871-01_13_1/page/189" title="read fulltext microfilm" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Archive [Microfilm] <div class="menu fulltext-thumbnail"> <img src="https://archive.org/serve/sim_congregational-quarterly_1871-01_13_1/__ia_thumb.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a>

Page 509 of MH: Mental Hygiene Vol. 28, Issue 3 [page]

<span title="">1944</span> <i title="National Mental Health Association"> <a target="_blank" rel="noopener" href="https://archive.org/details/pub_mh-mental-hygiene" style="color: black;">MH: Mental Hygiene </a> </i> &nbsp;
Bernard Samuel, Mayor of Philadelphia; Hon. S. M. K. O’Hara, State Secre- tary of Welfare; and Dr. Eugene Pendergrass, President of the Philadelphia County Medical Society.  ...  Estabrook, Secretary of the Mental Hygiene and Public Health Division of the Public Charities Association of Pennsylvania, and the other by Dr.  ... 
<span class="external-identifiers"> </span>
<a target="_blank" rel="noopener" href="https://archive.org/details/sim_mh-mental-hygiene_1944-07_28_3/page/509" title="read fulltext microfilm" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Archive [Microfilm] <div class="menu fulltext-thumbnail"> <img src="https://archive.org/serve/sim_mh-mental-hygiene_1944-07_28_3/__ia_thumb.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a>

Page 734 of Water Environment Research Vol. 22, Issue 5 [page]

<span title="">1950</span> <i title="Water Environment Federation"> <a target="_blank" rel="noopener" href="https://archive.org/details/pub_water-environment-research" style="color: black;">Water Environment Research </a> </i> &nbsp;
Bidg Omaha 2, Nebraska HITCHCOC K & ESTABROOK, INC.  ...  Hill Samuel M. Clarke Samuel A. Greeley Paul E. Langdon Thomas M. Niles Water Supply, Water Purification Sewerage, Sewage Treatment Flood Control, Drainage, Refuse Disposal 220 8.  ... 
<span class="external-identifiers"> </span>
<a target="_blank" rel="noopener" href="https://archive.org/details/sim_water-environment-research_1950-05_22_5/page/734" title="read fulltext microfilm" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Archive [Microfilm] <div class="menu fulltext-thumbnail"> <img src="https://archive.org/serve/sim_water-environment-research_1950-05_22_5/__ia_thumb.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a>

Page 234 of Congregational Quarterly Vol. 20, Issue 1 [page]

<span title="">1878</span> <i title="Open Court Publishing Co"> <a target="_blank" rel="noopener" href="https://archive.org/details/pub_congregational-quarterly" style="color: black;">Congregational Quarterly </a> </i> &nbsp;
Estabrook, Joseph, Ypsilanti, Mich. Ethridge, Albert, Marseilles, Il,  ...  R., Fitchburg, Mass 115 Eaton, Samuel W., Lancaster, Wis. 105 Ebbs, Edward, Plainfield, Ill. 19 Eckman, James K., Bloomington, Kan. Ecob, James H., Augusta, Me. Eddy, Hiram, Jersey City, N. J.  ... 
<span class="external-identifiers"> </span>
<a target="_blank" rel="noopener" href="https://archive.org/details/sim_congregational-quarterly_1878-01_20_1/page/234" title="read fulltext microfilm" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Archive [Microfilm] <div class="menu fulltext-thumbnail"> <img src="https://archive.org/serve/sim_congregational-quarterly_1878-01_20_1/__ia_thumb.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a>
&laquo; Previous Showing results 1 &mdash; 15 out of 713 results