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SPHN - The BioMedIT Network: A Secure IT Platform for Research with Sensitive Human Data

Diana Coman Schmid, Katrin Crameri, Sabine Oesterle, Bernd Rinn, Thierry Sengstag, Heinz Stockinger, BioMedIT network team
2020 Studies in Health Technology and Informatics  
The BioMedIT project is funded by the Swiss government as an integral part of the Swiss Personalized Health Network (SPHN), aiming to provide researchers with access to a secure, powerful and versatile  ...  The BioMedIT network gives researchers the ability to securely transfer, store, manage and process sensitive research data.  ...  Conclusion BioMedIT provides data resources and a network of secure data nodes for doing datadriven research on sensitive (confidential) biomedical data.  ... 
doi:10.3233/shti200348 pmid:32570566 fatcat:fqyjeoclybdcnfkgfhothsn6lu

SPHN - The Swiss Personalized Health Network Initiative

Adrien K Lawrence, Liselotte Selter, Urs Frey
2020 Studies in Health Technology and Informatics  
SPHN contributes to the development, the implementation, and the validation of coordinated infrastructures in order to make health-relevant data interoperable and shareable for research in Switzerland.  ...  The Swiss Personalized Health Network (SPHN) is a national initiative designed to promote the development of personalized medicine and personalized health in Switzerland.  ...  SPHN rallies all decision makers from key clinical, research and research support institutions around the same table.  ... 
doi:10.3233/shti200344 pmid:32570562 fatcat:3rqpiea3xzgxtexdds4baekwsu

DCC Terminology Service—An Automated CI/CD Pipeline for Converting Clinical and Biomedical Terminologies in Graph Format for the Swiss Personalized Health Network

Philip Krauss, Vasundra Touré, Kristin Gnodtke, Katrin Crameri, Sabine Österle
2021 Applied Sciences  
One goal of the Swiss Personalized Health Network (SPHN) is to provide an infrastructure for FAIR (Findable, Accessible, Interoperable and Reusable) health-related data for research purposes.  ...  To enable the integrative use of different terminologies, a terminology service is a important component of the SPHN Infrastructure for FAIR data.  ...  Acknowledgments: The authors would like to thank Shubham Kapoor and the sciCORE team of the University of Basel for their support in the setup of the MinIO server.  ... 
doi:10.3390/app112311311 fatcat:hcbbjbhiwjhbpfb4jv2fednm6q

SwissPK cdw – A clinical data warehouse for the optimization of pediatric dosing regimens

Roland Goers, Diana Coman Schmid, Vera F. Jäggi, Paolo Paioni, Michal J. Okoniewski, Althea Parker, Beat Bangerter, Sofia Georgakopoulou, Thierry Sengstag, Julia Bielicki, Romy Tilen, Swen Vermeul (+4 others)
2021 CPT: Pharmacometrics & Systems Pharmacology  
Embedded into the secure BioMedIT network, the CDW can connect to various data providers and researchers in order to collaborate on the data securely.  ...  , data analysis, and web tools in a secure scientific data and information technology (IT) environment.  ...  environment (Leonhard Med, 22 the data and IT platform of the BioMedIT Node Zürich).  ... 
doi:10.1002/psp4.12723 pmid:34729953 pmcid:PMC8673996 fatcat:66w6jdratzdyfdyf5baog5rbbe

Clinical data for paediatric research: the Swiss approach

Milenko Rakic, Manon Jaboyedoff, Sara Bachmann, Christoph Berger, Manuel Diezi, Philipp do Canto, Christopher B. Forrest, Urs Frey, Oliver Fuchs, Alain Gervaix, Amalia Stefani Gluecksberg, Michael Grotzer (+14 others)
2021 BMC Proceedings  
The Swiss Personalised Health Network (SPHN) aims to improve the use of data obtained during routine healthcare encounters by harmonizing data across Switzerland and facilitating accessibility for research  ...  Here, we describe the results of a two-day symposium that aimed to summarise what had been achieved in the SwissPedData project, to put it in an international context, and to discuss the next steps for  ...  Acknowledgements The authors would like to thank the speakers of the symposium and all the people who helped with the organization and coordination: Katrin Crameri, Alex Leichtle, Katie Harron, Peter Merkus  ... 
doi:10.1186/s12919-021-00226-3 pmid:34538238 fatcat:kpjbqo56prac3iebkw7fkpwely

Cohort profile: The Swiss Transplant Cohort Study (STCS): A nationwide longitudinal cohort study of all solid organ recipients in Switzerland

Susanne Stampf, Nicolas J Mueller, Christian van Delden, Manuel Pascual, Oriol Manuel, Vanessa Banz, Isabelle Binet, Sabina De Geest, Pierre-Yves Bochud, Alexander Leichtle, Stefan Schaub, Jürg Steiger (+1 others)
2021 BMJ Open  
of them for kidney and liver transplants.  ...  The STCS genomic data set includes around 3000 patients.Findings to dateDetailed clinical and laboratory data in high granularity as well as patient-reported outcomes from transplant recipients and activities  ...  The STCS considers all data as sensitive and therefore enforces the use of a highly secured tenant hosted with the BioMedIT network of the Swiss Personalised Health Network (SPHN).  ... 
doi:10.1136/bmjopen-2021-051176 pmid:34911712 pmcid:PMC8679072 fatcat:3sf6s6zl3rfqhinttbgv3xbpc4

Symposium report: One Health meets sequencing

Adrian Egli, Daniel Koch, Jürg Danuser, Rene S Hendriksen, Susanne Driesen, Diana Coman Schmid, Richard Neher, Mirjam Mäusezahl, Helena Mb Seth-Smith, Guido Bloemberg, Sarah Tschudin-Sutter, Andrea Endimiani (+4 others)
2019
Therefore we have organized a symposium on this technology with a focus on current and future applications in the field of "One Health".  ...  This symposium brought together leading institutions and fostered the ongoing discussion on the identified challenges, paving the way for solutions in public health, diagnostics, and research.  ...  Research data may classify as confidential (based on the SPHN IT Security Policy (15) and on the Leonhard Med Acceptable Use Policy) if: (i) it is sensitive personal data (Federal Act on Data Protection  ... 
doi:10.7892/boris.132544 fatcat:kuwgfdggqnd6db55o6d2sueahm

ELIXIR Annual Report 2020 [article]

ELIXIR
2021
and transferring data including sensitive human data.  ...  lead insTiTuTe SIB Swiss Institute of Bioinformatics WeBsiTe www.sib.swiss z Tailored a secure infrastructure network, BioMedIT, to provide all authorised researchers in Switzerland with easy  ...  The difference between the value of these contributions valued in Euros at the date of payment and the date of the approval of the 2020 budget was a loss of €36k (2019: loss of €68k).  ... 
doi:10.7490/f1000research.1118580.1 fatcat:saezbeodv5cpxoxfbh55pxjvwa

GA4GH: International policies and standards for data sharing across genomic research and healthcare

Heidi L Rehm, Angela J H Page, Lindsay Smith, Jeremy B Adams, Gil Alterovitz, Lawrence J Babb, Maxmillian P Barkley, Michael Baudis, Michael J S Beauvais, Tim Beck, Jacques S Beckmann, Sergi Beltran (+19 others)
2021
of humans, with increasing levels of diversity.  ...  The decreasing cost of genomic sequencing (along with other genome-wide molecular assays) and increasing evidence of its clinical utility will soon drive the generation of sequence data from tens of millions  ...  Baudis acknowledges funding from the BioMedIT Network project of Swiss Institute of Bioinformatics (SIB) and Swiss Personalized Health Network (SPHN); B.M.K. acknowledges funding from the Canada Research  ... 
doi:10.5167/uzh-210474 fatcat:2zuvemzcarb6rorzc4wduhweke

Cohort profile: The Swiss Transplant Cohort Study (STCS): A nationwide longitudinal cohort study of all solid organ recipients in Switzerland

Susanne Stampf, Nicolas J Mueller, Christian Van Delden, Manuel Pascual, Oriol Manuel, Vanessa Banz, Isabelle Binet, Sabina De Geest, Pierre-Yves Bochud, Alexander Leichtle, Stefan Schaub, Jürg Steiger (+2 others)
2021
Future plans The STCS will deepen its efforts in personalised medicine and digital epidemiology, and will also focus on allocation research and the use of causal inference methods to make complex matters  ...  research in the framework of Swiss transplantation medicine.  ...  The STCS considers all data as sensitive and therefore enforces the use of a highly secured tenant hosted with the BioMedIT network of the Swiss Personalised Health Network (SPHN).  ... 
doi:10.5167/uzh-212810 fatcat:3japzn2mnrg6di5f6hzhtoa5aq

Cohort profile: The Swiss Transplant Cohort Study (STCS): A nationwide longitudinal cohort study of all solid organ recipients in Switzerland

Susanne Stampf, Nicolas J. Mueller, Christian Van Delden, Manuel Pascual, Oriol Manuel, Vanessa Banz, Isabelle Binet, Sabina De Geest, Pierre-Yves Bochud, Alexander Leichtle, Stefan Schaub, Jürg Steiger (+3 others)
2021
Future plans The STCS will deepen its efforts in personalised medicine and digital epidemiology, and will also focus on allocation research and the use of causal inference methods to make complex matters  ...  research in the framework of Swiss transplantation medicine.  ...  The STCS considers all data as sensitive and therefore enforces the use of a highly secured tenant hosted with the BioMedIT network of the Swiss Personalised Health Network (SPHN).  ... 
doi:10.5451/unibas-ep85834 fatcat:7gtsag2tuzf5pcfoy3i2iiovzm