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Sibios as a Framework for Biomarker Discovery Using Microarray Data [article]

Bhavna Choudhury, IUPUI University Library, IUPUI # Defaults To Publisher
The main purpose of this research was to develop SIBIOS (Bystem for Integration of Bioinformatics Services) as a platform to carry out microarray experiments for the purpose of biomarker discovery.  ...  These tools and databases are often termed as 'bioinformatics services'.  ...  In-silico refers to the use of computer simulation. SIBIOS, a System for Integration of BIOinformatics Services is developed for biological researchers.  ... 
doi:10.7912/c2/839 fatcat:r6e4trl4i5aidnaju3isj56ux4

V-Lab-Protein: Virtual Collaborative Lab for protein sequence analysis

Jong Youl Choi, Youngik Yang, Sun Kim, Dennis Gannon
2007 2007 IEEE International Conference on Bioinformatics and Biomedicine Workshops  
We believe that this system design principle will be a new and effective paradigm for small biology research labs to handle the ever-increasing biological data.  ...  This is the first system of its kind that combines flexible workflow systems and on-demand compute and data resources (Amazon EC2/S3 in this case).  ...  SIBIOS (Systems for the Integration of Bioinformatics Services) [11] has been developed in the focus of dynamic workflow execution and interoperability between distributed and heterogeneous bioinformatics  ... 
doi:10.1109/bibmw.2007.4425417 fatcat:zoybsmdq5rcc7agssuz65hukwa

BioVLAB-Microarray: Microarray Data Analysis in Virtual Environment

Youngik Yang, Jong Youl Choi, Kwangmin Choi, Marlon Pierce, Dennis Gannon, Sun Kim
2008 2008 IEEE Fourth International Conference on eScience  
Here, we introduce a virtual analysis system for microarray gene expression data in computing clouds with flexible and configurable GUI workflow engine so that biologists are able to analyze the data in  ...  Microarray technology is a high-throughput experimental technique that can measure expression levels of hundreds of thousands of genes simultaneously.  ...  ACKNOWLEDGMENT The work is partially supported by NSF MCB 0731950 and a MetaCyt Microbial Systems Biology grant from Lilly Foundations.  ... 
doi:10.1109/escience.2008.57 dblp:conf/eScience/YangCCPGK08 fatcat:ywzt37aovjcxnokzziiqyx4fiy

Dynamic integration of biological data sources using the data concierge

Peng Gong
2013 Health Information Science and Systems  
However, existing integration technologies lack sufficient flexibility to adapt to these changes, because the techniques used for integration are static, and sensitive to new or changing bioinformatics  ...  The ever-changing landscape of large-scale network environments and innovative biology technologies require dynamic mechanisms to rapidly integrate previously unknown bioinformatics sources at runtime.  ...  The author also would like to express his gratitude to the Department of PET and Nuclear Medicine, RPA hospital for the supports and research facilities.  ... 
doi:10.1186/2047-2501-1-7 pmid:25825659 pmcid:PMC4340781 fatcat:wbzigvv3wfaghb4hkpkkyzxqda

Conservation of Intrinsic Disorder in Protein Domains and Families: II. Functions of Conserved Disorder

Jessica Walton Chen, Pedro Romero, Vladimir N. Uversky, A. Keith Dunker
2006 Journal of Proteome Research  
Ranking of CPD Regions In order to focus on a smaller number of CPD regions, a scoring system was devised to indicate the priority level for each conserved disorder region.  ...  Methods A. Materials Hardware All work was performed on a personal computer with a Pentium 4, 2.08e GHz processor and 512 MB of RAM, running Windows XP, Service Pack 2.  ...  of the SIBIOS (Service Integration for Bioinformatics Services) project.  ... 
doi:10.1021/pr060049p pmid:16602696 pmcid:PMC2533134 fatcat:txy7av2ccvfypbfognaigfoq6q

Predictive Resource Management for Scientific Workflows [article]

Carl Philipp Witt, Humboldt-Universität Zu Berlin
However, like distributed resource managers, they do not automatically determine the amount of resources required for executing individual tasks in a workflow.  ...  In contrast to prior work, an integrated perspective on prediction and scheduling is taken, which introduces various challenges, such as quantifying the effects of prediction errors on system performance  ...  Workflow Management System Integration For applying the proposed prediction method in practice, a few problems have to be solved.  ... 
doi:10.18452/21608 fatcat:7qxg2sx36zayjm362cl2elqeha