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SCit: web tools for protein side chain conformation analysis
2004
Nucleic Acids Research
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SCit is a web server providing services for protein side chain conformation analysis and side chain positioning. ...
Based on this concept, SCit uses sets of rotameric conformations dependent on the local backbone conformation of each protein for side chain positioning and the identification of side chains with unlikely ...
Chomilier for suggesting the integration of our collection of tools related to side chains. This work ...
doi:10.1093/nar/gkh388
pmid:15215438
pmcid:PMC441526
fatcat:n6zzrgbwafhrdkpquj3u5hoesy
RPBS: a web resource for structural bioinformatics
2005
Nucleic Acids Research
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As an illustration, we focus here on three such methods uniquely available at RPBS: AUTOMAT for sequence databank scanning, YAKUSA for structure databank scanning and WLOOP for homology loop modelling. ...
Funding to pay the Open Access publication charges for this article was provided by INSERM. ...
Other RPBS tools deal directly with 3D structures, such as SA-Search for finding structural similarities based on a structural alphabet (6) and Scit for comparing side chain conformations (7) . ...
doi:10.1093/nar/gki477
pmid:15980507
pmcid:PMC1160237
fatcat:22ndjqozljgjbb2oita5jcxpbq
Allergen Immunotherapy: Current and Future Trends
2022
Cells
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These modified allergens induce clinical-immunological effects similar to those mentioned above, increasing the tolerance to other related allergens but with fewer side effects. ...
Allergen immunotherapy (AIT) is the sole disease-modifying treatment for allergic rhinitis; it prevents rhinitis from progressing to asthma and lowers medication use. ...
Indeed, proteomics applications include in vitro diagnostics, allergen discovery, and the analysis of biologicals proposed for AIT [190, 191] . ...
doi:10.3390/cells11020212
pmid:35053328
pmcid:PMC8774202
fatcat:xr3czkdlwbairmol2wnlztb62y
Blind men and elephants: What do citation summaries tell us about a research article?
2007
Journal of the American Society for Information Science and Technology
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A citation summary is the set of citing sentences for a given article and can be used as a surrogate for the actual article in a variety of scenarios. ...
Although T7-based approaches for amplification of mRNA have been described [14][15][16][17], these rely on the 3' polyA tails for priming and incorporation of the T7 promoter. ...
SCit is a web server providing services for protein side chain conformation analysis and side chain positioning. ...
doi:10.1002/asi.20707
fatcat:qag4dzsinfe27edhmomzfxohay
Comparative structural analysis of haemagglutinin proteins from type A influenza viruses: conserved and variable features
2014
BMC Bioinformatics
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Current analyses of viral evolution are based on serological and primary sequence comparison; however, comparative structural analysis of capsidic proteins can provide functional insights on surface regions ...
However, viral evolution and spreading is strongly influenced by immunogenic features and capacity to bind host cells, depending in turn on the two major capsidic proteins. ...
Given that distribution of surface charge is strongly influenced by the orientation of side chains, models refinement was performed using a number of tools based on different algorithms: SCWRL [35, 36 ...
doi:10.1186/s12859-014-0363-5
pmid:25492298
pmcid:PMC4265342
fatcat:5lt2vc5k75h37kh7g4du2g66ye
Structure of Nitric Oxide Synthase Oxygenase Dimer with Pterin and Substrate
1998
Science
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geiotype were obtaned by cell sortng a i d simulated for 8 hours w~th C o i A (5 p.g/ml) before preparatoi of a cytospi. ...
nitric oxide (NO), which ronal NOS (nNOS, NOS1) and endotheliis a key intercellular signal and defensive a1 NOS (eNOS, NOS3) Produce low N O cytotoxin in the nerL70us, muscular, cardio-concentrations for ...
The goal of the analysis presented here otherwise regulated is a common tool for species conservation. ...
doi:10.1126/science.279.5359.2121
pmid:9516116
fatcat:j4voskxz7jfz3prkv4aziu3crq
Local Protein Structures
2007
Current Bioinformatics
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They have also been used to predict the protein backbone conformation and in ab initio / de novo methods. ...
Structural alphabets have been used to approximate and analyze local protein structures and to predict backbone conformation. This paper is divided in two parts. ...
One application of this structural alphabet has been the web server SCit that allows analysing the protein side chain conformation [315] . ...
doi:10.2174/157489307781662105
fatcat:wosaroff5jhcnojc7zlozpvd5e
Krit 1 interactions with microtubules and membranes are regulated by Rap1 and integrin cytoplasmic domain associated protein-1
2007
The FEBS Journal
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We show that, like other FERM proteins, Krit1 adopts two conformations: a closed conformation in which its N-terminal NPAY motif interacts with its C-terminus and an opened conformation bound to ICAP-1 ...
As evidence suggests a role for Krit1 in Rap1-dependent pathways, we readdressed this question. Here, we demonstrate by biochemical assays that Krit1 is a specific Rap1 effector. ...
ACKNOWLEDGEMENTS We are thankful to Frédéric Brau for excellent technical support in confocal microscopy. We ...
doi:10.1111/j.1742-4658.2007.06068.x
pmid:17916086
pmcid:PMC2580780
fatcat:66n26qxwnbgcpf4cv5wcwfkqpm
Dynamic and Electrostatic Effects on the Reaction Catalyzed by HIV-1 Protease
2016
Journal of the American Chemical Society
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The role of the protein dynamic was studied by protein isotope labelling in the framework of the Variational Transition State Theory. ...
On the contrary, the electric field created by the protein in the active site of the enzyme emerges as being critical for the electronic reorganization required during the reaction. ...
The position of the peptide in the active site was based on the arrangement with LP-130, and was build using Discovery Studio program version 3.5. 57 Using SCit tool developed by Tufféry and co-workers ...
doi:10.1021/jacs.6b06856
pmid:27935692
pmcid:PMC5178878
fatcat:xdlhjr2645cwndwktoiujhgi3u
Proceedings of the Canadian Society of Allergy and Clinical Immunology Annual Scientific Meeting 2020
2021
Allergy, Asthma & Clinical Immunology
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We identified 10 hot spot census tracts each for pediatric asthma ED visit and re-visit rates. ...
Methods: We performed a single centre retrospective cohort study of children ages 1-17 with one or more ED visits for asthma at the Children's Hospital of Eastern Ontario. ...
analysis. ...
doi:10.1186/s13223-021-00519-4
pmid:33785055
fatcat:twbwrkposjal7hhut2oy5ebkle
Sedentary behaviour as a risk factor for cardiovascular diseases in pediatric age
2014
Italian Journal of Pediatrics
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The first pneumococcal conjugate vaccine (PCV7) included 7 serotypes and was licensed for the use in infants and in children < 5 years. ...
Recently, preparations containing a greater number of pneumococcal serotypes have been developed and one of them, that including the greatest number of serotypes (PCV13), has been licensed for the use ...
This web-application is protected by an authentication system, a relief tool articulated in multilevel access profile for data legal protection and patients' privacy. ...
doi:10.1186/1824-7288-40-s1-a22
pmcid:PMC4132545
fatcat:zqwmnovq55fcjgfrxvul65v5mq
XXIV World Allergy Congress 2015
2016
The World Allergy Organization Journal
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For providing allergen extracts which were used for NPT, we also appreciate Research Center for Standardization of Allergic Diseases (RCSAD) of Yonsei University supported by a grant from the Korea Healthcare ...
We thank to ThermoFisher Scientific Korea for support in measuring serum total and allergenspecific IgE/IgG 4 (ImmunoCAP®). ...
Retrospectively with the medical chart review we investigated the incidence of side reaction of SCIT, relationship between the doses, concentration of allergen. ...
doi:10.1186/s40413-016-0096-1
fatcat:k2f4tpykangjzlbkzfpiliyzm4
Late Breaking Poster Session LB TPS
2017
Allergy. European Journal of Allergy and Clinical Immunology
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Statistical analysis was performed using SPSS software. ...
The new treatment was accepted by patients, with many children preferring the taste of the new treatment and experiencing minimal side effects. ...
Big food chain restaurants were not included in this study. ...
doi:10.1111/all.13249
fatcat:kjxhdffwuva3tgvl4qjeced64u
Risks from Low Doses of Radiation: Continued
1996
Science
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Astronomy, Chemistry and Biochemistry Departments of UCLA in collaboration with the Jules Stein Eye Institute of the UCLA Medical School, which has active biophysics-related research programs that include protein-folding ...
Exceptionally well-qualified junior applicants will also be considered for appointment at the assistant or associate professor level. ...
Research will focus on the development of novel algorithms and software tools for the analysis of molecular sequence data and for the automation of primary and tertiary structures. ...
doi:10.1126/science.273.5275.561d
fatcat:judbhnacbjgknmogqkklrjfo5y
EAACI Molecular Allergology User's Guide
2016
Pediatric Allergy and Immunology
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This information provides the basis for a refined , earlier , diagnosis of the allergic reactions and ultimately for a tailored individualized management of the patient, including opportunities for prevention ...
This User's Guide for Molecular Allergology will be another breakthrough in this regard. ...
We would like to thank Araceli Dıaz-Perales, from ETSIA UPM, Madrid, for providing the figure on melon profilin in Section C01, as well as Figure 1 in Section C03. ...
doi:10.1111/pai.12563
pmid:27288833
fatcat:u64c6gm5enhj7h6g4r5xddnk6u
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