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An efficient simulated annealing algorithm for the RNA secondary structure prediction with Pseudoknots

Zhang Kai, Wang Yuting, Lv Yulin, Liu Jun, He Juanjuan
2019 BMC Genomics  
RNA pseudoknot structures play an important role in biological processes. However, existing RNA secondary structure prediction algorithms cannot predict the pseudoknot structure efficiently.  ...  The experimental results have been demonstrated to provide a competitive and oftentimes better performance when compared against some chosen state-of-the-art RNA structure prediction algorithms.  ...  SARNA-predict-pk [14] algorithm is an extended version of SARNA-Predict [10] which predicts RNA secondary structures with pseudoknots.  ... 
doi:10.1186/s12864-019-6300-2 pmid:31881969 pmcid:PMC6933665 fatcat:6u2w77izs5e6hk3vhmlz7zkqqy