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New Literacy Narratives from an Urban University: Analyzing Stories About Reading, Writing, and Changing Technologies by Sally Chandler with Angela Castillo, Maureen Kadash, Molly D. Kenner, Lorena Ramirez, and Ryan J. Valdez

Gwen Gorzelsky
2014 Literacy in Composition Studies  
The potential value of analyzing one's own literacy narratives emerges further in Chapter Seven, "Making Room for Multiple Literacies. " Co-author Ryan Valdez, a young adult master's student in English  ... 
doi:10.21623/ fatcat:pnfqtlchivaedoi7fkhbj2trvq

Subjective and Real Time: Coding Under Different Drug States

Hugo Sanchez-Castillo, Kathleen M. Taylor, Ryan D. Ward, Diana B. Paz-Trejo, Maria Arroyo-Araujo, Oscar Galicia Castillo, Peter D. Balsam
2015 International Journal of Comparative Psychology  
The mechanism underlying the perception, encoding, and retrieval of temporal regularities in the seconds and minutes range is referred to as interval timing (Boisvert & Sherry, 2006; Balsam, Sanchez-Castillo  ... 
doi:10.46867/ijcp.2015.28.02.02 fatcat:572u4dwbnfagdajnfs5xapeepm

Glioblastoma Multiforme: Relationship to Subventricular Zone and Recurrence

Margareth Kimura, Yeuh Lee, Ryan Miller, Mauricio Castillo
2013 The Neuroradiology Journal  
Neurogenesis in the adult mammalian brain is active in two areas: the subgranular zone in the dentate gyrus of the hippocampus and the subventricular zone. Cancer stem cells have been isolated from malignant brain tumors and it is widely believed they arise from transformed endogenous stem cells. We sought to determine if the initial location of glioblastoma (GB) as seen on conventional MRI and its relationship to the subventricular zone (SVZ) predicts the pattern of recurrence. We analyzed the
more » ... initial (prior to any treatment) and last follow-up MR studies in 49 patients with GB. On post contrast images all non-treated GB were divided into three groups according to the relationship of their enhancing margins to the SVZ: Group I (directly in contact with the SVZ), Group II (in the subcortical [SC] region) and Group III (in both the SVZ and SC regions). Recurrences or continuous growth seen as enhancing areas on follow-up studies were characterized as local, spread, or distant according to their contact with the surgical bed and correlated with the locations of the initial tumors. Local and spread patterns of recurrence occurred with nearly equal frequency (45 and 43% each, respectively) and distant in 12%. In Group I, 80% showed a spread pattern, 20% a local pattern, and none a distant pattern. In Group II, 45% showed a spread pattern, 35% a local pattern, and a 20% distant one. In Group III, 58% showed a local pattern, 33% a spread pattern, and 8% distant one. Unlike other reports, the location of GB in relation to the SVZ in our patients did not predict the pattern of tumor recurrence and/or extension in our patients.
doi:10.1177/197140091302600507 pmid:24199814 pmcid:PMC4202832 fatcat:nqzrtojldrdbve46jvawxis5dq

Pneumothorax bei COVID-19-Erkrankung – Inzidenz und klinische Merkmale

Massa Zantah, Eduardo Dominguez-Castillo, Ryan Townsend, Fusun Dikengil, Gerard J. Criner
2020 Karger Kompass Pneumologie  
Hintergrund: Der Spontanpneumothorax ist eine selten auftretende Komplikation der Viruspneumonie bei COVID-19. Die genaue Inzidenz sowie die Risikofaktoren sind weiter unklar. In der vorliegenden Arbeit untersuchen wir die Inzidenz und die Outcomes von mehr als 3.000 Patienten mit Pneumothorax, die mit Verdacht auf COVID-19-Pneumonie in unsere Klinik aufgenommen wurden. Methoden: Wir überprüften retrospektiv die Fälle von COVID-19-Patienten, die in unsere Klinik aufgenommen worden waren. Zur
more » ... echnung der Inzidenz dieses Ereignisses wurden Patienten mit diagnostiziertem Spontanpneumothorax identifiziert und ihre klinischen Merkmale wurden umfassend dokumentiert. Es wurden Daten zum klinischen Outcome erhoben. Die einzelnen Fälle werden jeweils in Form einer kurzen Zusammenfassung vorgestellt. Ergebnisse: Zwischen 1. März und 8. Juni 2020 wurden 3368 Patienten mit Verdacht auf eine COVID-19-Pneumonie in unsere Klinik aufgenommen; von diesen wiesen 902 Patienten einen positiven Nasopharyngealabstrich auf. Es wurden sechs COVID-19-Patienten, die einen Spontanpneumothorax entwickelten, identifiziert (0,66 %). Die Baseline-Bildgebung zeigte bei diesen Patienten diffuse bilaterale Milchglastrübungen und Konsolidierungen, überwiegend in den posterioren und peripheren Lungenregionen. Vier der sechs Patienten wurden mechanisch beatmet. Bei allen Patienten war eine Thoraxdrainage erforderlich. In allen Fällen bestand kein direkter Zusammenhang zwischen dem Pneumothorax und der Mortalität (66,6%). Schlussfolgerung: Der Spontanpneumothorax ist eine seltene Komplikation der Viruspneumonie bei COVID-19, die auch ohne mechanische Beatmung auftreten kann. Kliniker sollten im Hinblick auf die Diagnose und Behandlung dieser Komplikation wachsam sein.
doi:10.1159/000513501 fatcat:bcrylncjmjaqzmnptpoxsfhomm

Timing and anticipation: conceptual and methodological approaches

Peter Balsam, Hugo Sanchez-Castillo, Kathleen Taylor, Heather Van Volkinburg, Ryan D. Ward
2009 European Journal of Neuroscience  
Anticipation occurs on timescales ranging from milliseconds to hours to days. This paper relates the theoretical and methodological developments in the study of interval timing in the seconds, minutes and hours range to research on the anticipatory activity induced by regularly timed daily meals. Daily food anticipatory activity (FAA) is entrained by procedures which are formally identical to procedures studied in Pavlovian and Operant conditioning except for the long duration of the interval
more » ... tween feeding opportunities. As in FAA, the conditioning procedures induce orderly anticipatory activity in advance of food presentation. During the interval between foods the behaviors that express anticipation change as the interval progresses. Consequently, no single response represents a pure measure of anticipation. The ability to distinguish between properties of general anticipatory timing mechanisms such as the scalar property (Gibbon, 1977) and dynamic properties of specific response output systems has been facilitated by teaching animals to use arbitrary anticipatory responses like bar pressing to obtain food. Interval timing research highlights the importance of identifying the mechanisms of perception, memory, decision making and motivation that all contribute to food anticipation. We suggest that future work focused on the similarities and differences in the neural bases of FAA and interval timing may be useful in unravelling the mechanisms mediating timing behavior.
doi:10.1111/j.1460-9568.2009.06967.x pmid:19863656 pmcid:PMC2791343 fatcat:fh7uvspkn5hqrd5mkqzipmodm4

A Nebulin Ruler Does Not Dictate Thin Filament Lengths

Angelica Castillo, Roberta Nowak, Kimberly P. Littlefield, Velia M. Fowler, Ryan S. Littlefield
2009 Biophysical Journal  
We thank Ryan Gile, Stephanie Palacio, and Madrona Murphy for assistance with dissections, Drs. Wolfgang Linke and Katarina Pelin for helpful discussions and sharing data, and Drs.  ...  Castillo, K. P. Littlefield, and R. S. Littlefield, unpublished results). Based on the available literature, P-end extensions are likely to be present in other muscles and species.  ...  Castillo, R. Nowak, V. M. Fowler, and R. S. Littlefield, unpublished results). Secondary antibodies (Jackson ImmunoResearch, West Grove, PA) were used at the recommended 1:200 dilution.  ... 
doi:10.1016/j.bpj.2008.10.053 pmid:19254544 pmcid:PMC2717268 fatcat:oxa35fft3jfhlnbdv362zddfo4

The Phenomenon of Teenage Pregnancy in the Philippines

Jordan Tovera Salvador, Ben Ryan Jucay Sauce, Marc Oneel Castillo Alvarez, Ahrjaynes Balanag Rosario
2016 European Scientific Journal  
Teenage Pregnancy had been a worldwide issue, and has raised large numbers of campaigns and awareness to lessen its occurrence. The total number of this phenomenon is increasing each year. Philippines is one of the Asian countries which shares similar situation. In a study conducted by the National Demographic and Health Survey in 2013, one out of every young Filipino women age 15 to 19 is already a mother or pregnant with a first child. Therefore, the government in partnership with the
more » ... t nongovernment agencies should exert efforts in resolving this issue. Teenage Pregnancies are often associated with social development issues such as lack of sufficient education and poverty. This often results to single parenthood which catalyzes conditions that renders the mothers to become irresponsible. Hence, it conveys a social stigma in various countries and cultures. This study would like to focus on exploring the lived experiences of Filipino teenage mothers in their pre and post-natal stage on how they prepare and accept their new roles as mothers. The gathered data from the methods were analyzed and interpreted according to qualitative content analysis. As a result, this generated emergent themes which depicted the experiences of the participants.
doi:10.19044/esj.2016.v12n32p173 fatcat:vm6xrgartbarvhumz2nwswdgy4

Early detection of malaria foci for targeted interventions in endemic southern Zambia

Ryan G Davis, Aniset Kamanga, Carlos Castillo-Salgado, Nnenna Chime, Sungano Mharakurwa, Clive Shiff
2011 Malaria Journal  
Zambia has achieved significant reductions in the burden of malaria through a strategy of "scalingup" effective interventions. Progress toward ultimate malaria elimination will require sustained prevention coverage and further interruption of transmission through active strategies to identify and treat asymptomatic malaria reservoirs. A surveillance system in Zambia's Southern Province has begun to implement such an approach. An early detection system could be an additional tool to identify
more » ... of elevated incidence for targeted intervention. Methods: Based on surveillance data collected weekly from 13 rural health centres (RHCs) divided into three transmission zones, early warning thresholds were created following a technique successfully implemented in Thailand. Alert levels were graphed for all 52 weeks of a year using the mean and 95% confidence interval upper limit of a Poisson distribution of the weekly diagnosed malaria cases for every available week of historic data (beginning in Aug, 2008) at each of the sites within a zone. Annually adjusted population estimates for the RHC catchment areas served as person-time of weekly exposure. The zonal threshold levels were validated against the incidence data from each of the 13 respective RHCs. Results: Graphed threshold levels for the three zones generally conformed to observed seasonal incidence patterns. Comparing thresholds with historic weekly incidence values, the overall percentage of aberrant weeks ranged from 1.7% in Mbabala to 36.1% in Kamwanu. For most RHCs, the percentage of weeks above threshold was greater during the high transmission season and during the 2009 year compared to 2010. 39% of weeks breaching alert levels were part of a series of three or more consecutive aberrant weeks. Conclusions: The inconsistent sensitivity of the zonal threshold levels impugns the reliability of the alert system. With more years of surveillance data available, individual thresholds for each RHC could be calculated and compared to the technique outlined here. Until then, "aberrant" weeks during low transmission seasons, and during high transmission seasons at sites where the threshold level is less sensitive, could feasibly be followed up for household screening. Communities with disproportionate numbers of aberrant weeks could be reviewed for defaults in the scaling-up intervention coverage.
doi:10.1186/1475-2875-10-260 pmid:21910855 pmcid:PMC3182978 fatcat:tcjudnohdzalvpeop4g2ksstua

In Reply–The "Perfect Cytokine Storm" of COVID-19

Prakhar Vijayvargiya, Zerelda Esquer Garrigos, Natalia E. Castillo Almeida, Pooja R. Gurram, Ryan W. Stevens, Raymund R. Razonable
2020 Mayo Clinic proceedings  
doi:10.1016/j.mayocp.2020.05.016 pmid:32861344 pmcid:PMC7256601 fatcat:v5lsazcpyjag7oirumjrlktwq4

Diagnosis and Treatment of Tolosa-Hunt Syndrome in the Emergency Department

Kevin Olsen, Andrew Johnson, Sarah Castillo-Jorge, Jeffrey Bennett, Matthew F. Ryan
2017 Open Journal of Emergency Medicine  
We describe herein a patient who presented with painful ophthalmoplegia and was ultimately diagnosed via magnetic imaging resonance studies and successfully treated for Tolosa-Hunt syndrome. Tolosa-Hunt syndrome is a rare, reversible and painful ophthalmoplegia characterized by recurrent unilateral orbital pain, ipsilateral oculomotor paralysis and prompt response to steroids. Specific criteria for its diagnosis exist and are discussed herein. Individuals affected may display signs of select
more » ... nial nerve palsies, ptosis, facial numbness, diplopia, midrosis, and proptosis. Appropriate recognition of the disease can allow for immediate intervention and thus decrease the length and severity of symptoms especially as symptoms may not spontaneously resolve without treatment which leads to unnecessary suffering through pain, anxiety, and decreased vision. We describe the case presentation and keys for diagnosis emergency medicine that physicians should know for this potentially devastating condition.
doi:10.4236/ojem.2017.51001 fatcat:sw2k75n7yrbwpbfrfvtolikgkq

Managing Professional Development Activities for Non-teaching Staff: For Professional Growth

Djonde Frega A. Antiado, Fermin G. Castillo. Jr., James Ryan P. Reblando, Maher Ibrahim Tawadrous
2020 Universal Journal of Educational Research  
A knowledge-based economy, exponential changes in technology, increasing number of diverse students, call for innovativeness, community engagement, stiffer competition and demands for accountability put enormous demands in institutions of higher education. The non-teaching staff had taken significant roles in today's academic work environment. However, the challenges of the 21st century bring the non-teaching staff to be in front of the process. By using training needs analysis, we can
more » ... what professional development activities to be given. To ensure its sustainability, professional development programs must focus on and benefit the institution which includes both teaching and non-teaching staff. Nonteaching staffs play vital role in the academic environment because they are in the technical and support side of the educational institution. It is very important that nonteaching staffs should also be knowledgeable with their role and participation in the process. This paper is an eye opener to the top management on the value of non-teaching staff as they portray equally important role same as teaching staff.
doi:10.13189/ujer.2020.080758 fatcat:37n7j63gyjherfggxrwa4go2ye

Machine Learning Based Predictions of Dissolved Oxygen in a Small Coastal Embayment

Manuel Valera, Ryan K. Walter, Barbara A. Bailey, Jose E. Castillo
2020 Journal of Marine Science and Engineering  
Coastal dissolved oxygen (DO) concentrations have a profound impact on nearshore ecosystems and, in recent years, there has been an increased prevalance of low DO hypoxic events that negatively impact nearshore organisms. Even with advanced numerical models, accurate prediction of coastal DO variability is challenging and computationally expensive. Here, we apply machine learning techniques in order to reconstruct and predict nearshore DO concentrations in a small coastal embayment while using
more » ... comprehensive set of nearshore and offshore measurements and easily measured input (training) parameters. We show that both random forest regression (RFR) and support vector regression (SVR) models accurately reproduce both the offshore DO and nearshore DO with extremely high accuracy. In general, RFR consistently peformed slightly better than SVR, the latter of which was more difficult to tune and took longer to train. Although each of the nearshore datasets were able to accurately predict DO values using training data from the same site, the model only had moderate success when using training data from one site to predict DO at another site, which was likely due to the the complexities in the underlying dynamics across the sites. We also show that high accuracy can be achieved with relatively little training data, highlighting a potential application for correcting time series with missing DO data due to quality control or sensor issues. This work establishes the ability of machine learning models to accurately reproduce DO concentrations in both offshore and nearshore coastal waters, with important implications for the ability to detect and indirectly measure coastal hypoxic events in near real-time. Future work should explore the ability of machine learning models in order to accurately forecast hypoxic events.
doi:10.3390/jmse8121007 fatcat:atfvciqm6na5pmmt3axmdjvu4i

Trikafta therapy alters the CF lung mucus metabolome reshaping microbiome niche space [article]

Lauren Sosinski, Christian Martin-Hernandez, Kerri A Neugebauer, Lydia-Ann J Ghuneim, Douglas V Guzior, Alicia Castillo-Bahena, Jenna Mielke, Ryan Thomas, Marc McClelland, Doug Conrad, Robert A Quinn
2021 medRxiv   pre-print
Novel small molecule therapies for cystic fibrosis (CF) are showing promising efficacy and becoming more widely available since recent FDA approval. The newest of these is a triple therapy of Elexacaftor-Tezacaftor-Ivacaftor (ETI). Little is known about how these drugs will affect polymicrobial lung infections, which are the leading cause of morbidity and mortality among people with CF (pwCF). We analyzed the sputum microbiome and metabolome from pwCF (n=24) before and after TKT therapy using
more » ... S rRNA gene amplicon sequencing and untargeted metabolomics. The lung microbiome diversity, particularly its evenness, was increased (p = 0.044) and the microbiome profiles were different between individuals before and after therapy (PERMANOVA F=1.92, p=0.044). Despite these changes, the microbiomes were more similar within an individual than across the sampled population. There were no specific microbial taxa that were different in abundance before and after therapy, but collectively, the log-ratio of anaerobes to pathogens significantly decreased. The sputum metabolome also showed changes due to TKT. Beta-diversity increased after therapy (PERMANOVA F=4.22, p=0.022) and was characterized by greater variation across subjects while on treatment. This significant difference in the metabolome was driven by a decrease in peptides, amino acids, and metabolites from the kynurenine pathway. Metabolism of the three small molecules that make up TKT was extensive, including previously uncharacterized structural modifications. This study shows that TKT therapy affects both the microbiome and metabolome of airway mucus. This effect was stronger on sputum biochemistry, which may reflect changing niche spaces for microbial residency in lung mucus as the drug effects take hold, which then leads to changing microbiology.
doi:10.1101/2021.06.02.21257731 fatcat:ee6mhvnz55bmplry36xuzemti4

Antimicrobial Susceptibility ofBrucella melitensisIsolates in Peru

Ryan C. Maves, Rosa Castillo, Alfredo Guillen, Benjamin Espinosa, Rina Meza, Nereyda Espinoza, Gladys Núñez, Luis Sánchez, Jesús Chacaltana, David Cepeda, Sofía González, Eric R. Hall
2011 Antimicrobial Agents and Chemotherapy  
ABSTRACTBrucellosis is an important public health problem in Peru. We evaluated 48 humanBrucella melitensisbiotype 1 strains from Peru between 2000 and 2006. MICs of isolates to doxycycline, azithromycin, gentamicin, rifampin, ciprofloxacin, and trimethoprim-sulfamethoxazole were determined by the Etest method. All isolates were sensitive to tested drugs during the periods of testing. Relapses did not appear to be related to drug resistance.
doi:10.1128/aac.00979-10 pmid:21199926 pmcid:PMC3067062 fatcat:3l5jbqvz6rb2ddbigt5yyivf5e

Tectonic analysis of fracturing associated with occator crater

Debra L. Buczkowski, Jennifer E.C. Scully, Lynnae Quick, Julie Castillo-Rogez, Paul M. Schenk, Ryan S. Park, Frank Preusker, Ralf Jaumann, Carol A. Raymond, C.T. Russell
2018 Icarus (New York, N.Y. 1962)  
doi:10.1016/j.icarus.2018.05.012 fatcat:vbi5nqidqjek7mox52prq253zm
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