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Role of hippocampal CA1 atrophy in memory encoding deficits in amnestic Mild Cognitive Impairment

Marine Fouquet, Béatrice Desgranges, Renaud La Joie, Denis Rivière, Jean-François Mangin, Brigitte Landeau, Florence Mézenge, Alice Pélerin, Vincent de La Sayette, Fausto Viader, Jean-Claude Baron, Francis Eustache (+1 others)
<span title="">2012</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/sa477uo7lveh7hchpikpixop5u" style="color: black;">NeuroImage</a> </i> &nbsp;
Number of words in the abstract: 225; Number of words in the text: 3961; Number of characters in the title: 97.  ...  Otherwise, previous studies have reported a specific link between neuronal loss in CA1 and episodic memory impairment in AD (Zarow et al., 2005) or atrophy in CA1 and episodic memory deficits in mild  ...  In patients with amnestic Mild Cognitive Impairment (aMCI), the clinical entity that best represents the pre-dementia stage of AD (Petersen, 2005) , previous studies have consistently reported a relationship  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.neuroimage.2011.11.036">doi:10.1016/j.neuroimage.2011.11.036</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/22119654">pmid:22119654</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/elxol3rdancq7fec5ehlpf676e">fatcat:elxol3rdancq7fec5ehlpf676e</a> </span>
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Spatial navigation—a unique window into physiological and pathological aging

Ivana Gazova, Kamil Vlcek, Jan Laczó, Zuzana Nedelska, Eva Hyncicova, Ivana Mokrisova, Katerina Sheardova, Jakub Hort
<span title="">2012</span> <i title="Frontiers Media SA"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/xyafp6gbr5et3ghi4kqddnyolm" style="color: black;">Frontiers in Aging Neuroscience</a> </i> &nbsp;
The CA1 atrophy in patients with mild cognitive impairment (MCI) can even predict conversion to dementia due to AD (Chételat et al., 2008; Devanand et al., 2012) .  ...  More specifically, right CA1 hippocampal subfield seems to be involved in encoding of allocentric spatial information in humans (Suthana et al., 2009 ).  ...  Conflict of Interest Statement: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3389/fnagi.2012.00016">doi:10.3389/fnagi.2012.00016</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/22737124">pmid:22737124</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3380196/">pmcid:PMC3380196</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/vyewmnvfwfcuhoavpr5kczceyi">fatcat:vyewmnvfwfcuhoavpr5kczceyi</a> </span>
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Atrophy of presubiculum and subiculum is the earliest hippocampal anatomical marker of Alzheimer's disease

Giovanni A. Carlesimo, Fabrizio Piras, Maria Donata Orfei, Mariangela Iorio, Carlo Caltagirone, Gianfranco Spalletta
<span title="">2015</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/y5b3apqmfve23ds3kch2bvmcxa" style="color: black;">Alzheimer&#39;s and Dementia: Diagnosis, Assessment and Disease Monitoring</a> </i> &nbsp;
In AD patients, the volumes of all hippocampal subfields (with the notable exception of the CA1) predicted memory scores.  ...  Methods: Thirty AD patients, 41 mild cognitive impairment (MCI) patients, and 38 healthy controls (HCs) underwent cerebral magnetic resonance imaging (with an automated segmentation protocol for the volumetric  ...  Therefore, neuroradiological indexes of hippocampal atrophy [3, 4] and, consistent with the wellknown role of the hippocampus in human declarative memory [5] , episodic memory deficits [6, 7] are  ... 
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The Amnestic Syndrome of Hippocampal type in Alzheimer's Disease: An MRI Study

Marie Sarazin, Valérie Chauviré, Emilie Gerardin, Olivier Colliot, Serge Kinkingnéhun, Leonardo Cruz de Souza, Laurence Hugonot-Diener, Line Garnero, Stéphane Lehéricy, Marie Chupin, Bruno Dubois
<span title="2010-09-28">2010</span> <i title="IOS Press"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/uux5o5kf5zaednhl4637xcmbte" style="color: black;">Journal of Alzheimer&#39;s Disease</a> </i> &nbsp;
In AD, the FCSRT may be considered as a useful clinical marker of memory disorders due to medial temporal damage, specially the CA1 field of the hippocampus.  ...  regional atrophy and their scores for episodic memory using the FCSRT.  ...  In a previous longitudinal study with the follow-up of 251 patients with mild cognitive impairment (MCI), we showed that both free and total recall scores assessed by the FCSRT [12] were able to detect  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3233/jad-2010-091150">doi:10.3233/jad-2010-091150</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/20847406">pmid:20847406</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/wxkyit66rvfw7h7n22ui7uxfcu">fatcat:wxkyit66rvfw7h7n22ui7uxfcu</a> </span>
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Can multi-modal neuroimaging evidence from hippocampus provide biomarkers for the progression of amnestic mild cognitive impairment?

Jiu Chen, Zhijun Zhang, Shijiang Li
<span title="2015-01-16">2015</span> <i title="Springer Nature"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/urataqivtzgh5klmiluxki3kp4" style="color: black;">Neuroscience Bulletin</a> </i> &nbsp;
Impaired structure and function of the hippocampus is a valuable predictor of progression from amnestic mild cognitive impairment (aMCI) to Alzheimer's disease (AD).  ...  We propose a new sequential and progressive framework in which the impairment spreads from the integrity of fibers to volume and then to function in hippocampal subregions.  ...  Recently, Fouquet and colleagues have also demonstrated that memory-encoding deficits appear to be specifically linked to atrophy of the hippocampal CA1 subfield, while the episodic retrieval impairment  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1007/s12264-014-1490-8">doi:10.1007/s12264-014-1490-8</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/25595368">pmid:25595368</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC5562641/">pmcid:PMC5562641</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/6c4zmlk5brfdzmab4q7lpjjrda">fatcat:6c4zmlk5brfdzmab4q7lpjjrda</a> </span>
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Disrupted Functional Connectivity of Cornu Ammonis Subregions in Amnestic Mild Cognitive Impairment: A Longitudinal Resting-State fMRI Study

Hui Li, Xiuqin Jia, Zhigang Qi, Xiang Fan, Tian Ma, Ran Pang, Hong Ni, Chiang-Shan R Li, Jie Lu, Kuncheng Li
<span title="2018-10-29">2018</span> <i title="Frontiers Media S.A"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/adcuz6lgabeidhngmk32v7egkq" style="color: black;">Frontiers in Human Neuroscience</a> </i> &nbsp;
The cornu ammonis (CA), as part of the hippocampal formation, represents a primary target region of neural degeneration in amnestic mild cognitive impairment (aMCI).  ...  Longitudinal decrease in FC between the right CA1 and right MTG was correlated with reduced capacity of episodic memory in aMCI subjects.  ...  subjects with amnestic mild cognitive impairment (aMCI) and healthy control (HC).  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3389/fnhum.2018.00413">doi:10.3389/fnhum.2018.00413</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/30420801">pmid:30420801</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC6216144/">pmcid:PMC6216144</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/2a7hntcmsndljahakvkftyuke4">fatcat:2a7hntcmsndljahakvkftyuke4</a> </span>
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Memory Performance Correlates of Hippocampal Subfield Volume in Mild Cognitive Impairment Subtype

Kathryn M. Broadhouse, Loren Mowszowski, Shantel Duffy, Isabella Leung, Nathan Cross, Michael J. Valenzuela, Sharon L. Naismith
<span title="2019-11-21">2019</span> <i title="Frontiers Media SA"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/sx3lvh2nmvah7ilqdbdicsjcku" style="color: black;">Frontiers in Behavioral Neuroscience</a> </i> &nbsp;
The increased understanding that neuropathology begins decades before symptom onset, has led to the conceptualization and widespread utilization of Mild Cognitive Impairment (MCI) as an important transitional  ...  CA1 subfield volume was shown to predict concurrent memory performance in aMCI, while dentate gyrus volume significantly predicted longitudinal verbal learning and memory decline in the entire cohort.  ...  Further subcategorization into the clinical phenotypes of amnestic and non-amnestic MCI (aMCI and naMCI) (i.e., depending on whether impairment is evident in memory or non-memory cognitive domains, respectively  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3389/fnbeh.2019.00259">doi:10.3389/fnbeh.2019.00259</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/31849620">pmid:31849620</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC6897308/">pmcid:PMC6897308</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/kqyeri5ppfgh5hb5qktotuzlxq">fatcat:kqyeri5ppfgh5hb5qktotuzlxq</a> </span>
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Associative memory deficits in mild cognitive impairment: The role of hippocampal formation

M. Atienza, K.C. Atalaia-Silva, G. Gonzalez-Escamilla, E. Gil-Neciga, A. Suarez-Gonzalez, J.L. Cantero
<span title="">2011</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/sa477uo7lveh7hchpikpixop5u" style="color: black;">NeuroImage</a> </i> &nbsp;
memory deficits in non-demented people with mild cognitive impairment (MCI).  ...  encoding of associations.  ...  Acknowledgments We are grateful to all participants for their collaboration in this study.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.neuroimage.2011.05.047">doi:10.1016/j.neuroimage.2011.05.047</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/21640840">pmid:21640840</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/cft3qwpt2vag7lko6ykfdcamky">fatcat:cft3qwpt2vag7lko6ykfdcamky</a> </span>
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Hippocampal subfield surface deformity in nonsemantic primary progressive aphasia

Adam Christensen, Kathryn Alpert, Emily Rogalski, Derin Cobia, Julia Rao, Mirza Faisal Beg, Sandra Weintraub, M.-Marsel Mesulam, Lei Wang
<span title="2015-03-01">2015</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/y5b3apqmfve23ds3kch2bvmcxa" style="color: black;">Alzheimer&#39;s and Dementia: Diagnosis, Assessment and Disease Monitoring</a> </i> &nbsp;
Memory performance was related to hippocampal shape abnormalities in PPA patients, but not controls, even in the absence of memory impairments.  ...  This study examined hippocampal abnormalities in PPA to determine similarities to those described in amnestic AD.  ...  A pattern of memory impairment and hippocampal atrophy consistent with amnestic dementia was not expected in the PPA patients with an ε4 allele, because the ε4 allele in this diagnostic group does not  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.dadm.2014.11.013">doi:10.1016/j.dadm.2014.11.013</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/25893207">pmid:25893207</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC4398964/">pmcid:PMC4398964</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/srijn4xekrgd3gz3xlt2xzpfla">fatcat:srijn4xekrgd3gz3xlt2xzpfla</a> </span>
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Individual differences in associative memory among older adults explained by hippocampal subfield structure and function

Valerie A. Carr, Jeffrey D. Bernstein, Serra E. Favila, Brian K. Rutt, Geoffrey A. Kerchner, Anthony D. Wagner
<span title="2017-10-23">2017</span> <i title="Proceedings of the National Academy of Sciences"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/nvtuoas5pbdsllkntnhizy4f4q" style="color: black;">Proceedings of the National Academy of Sciences of the United States of America</a> </i> &nbsp;
Similarly, in vivo imaging studies of patients with mild cognitive impairment (MCI) (a clinical precursor to AD) and mild AD demonstrate focal atrophy in ERC (23-25) and CA1 (e.g., ref. 26), although some  ...  rodent and human postmortem literatures. episodic memory | hippocampus | aging | mild cognitive impairment | Alzheimer's disease E pisodic memory, or the capacity to encode and subsequently retrieve memories  ...  Data deposition: The human MRI data reported in this paper have been deposited in the Stanford Digital Repository (SDR), https://purl.stanford.edu/dm781xs5457. ACKNOWLEDGMENTS.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1073/pnas.1713308114">doi:10.1073/pnas.1713308114</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/29078387">pmid:29078387</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC5692588/">pmcid:PMC5692588</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/22ltzqkjezgm7pvj4sgsdtxz7u">fatcat:22ltzqkjezgm7pvj4sgsdtxz7u</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20190218222146/http://pdfs.semanticscholar.org/142a/2f415be12bb9fa31e2d4107c7fc89b445e2f.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/14/2a/142a2f415be12bb9fa31e2d4107c7fc89b445e2f.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1073/pnas.1713308114"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5692588" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

How does the hippocampal formation mediate memory for stimuli processed by the magnocellular and parvocellular visual pathways? Evidence from the comparison of schizophrenia and amnestic mild cognitive impairment (aMCI)

Szabolcs Kéri, András Szamosi, György Benedek, Oguz Kelemen
<span title="">2012</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/vtuexoohondejhlk4iamncfka4" style="color: black;">Neuropsychologia</a> </i> &nbsp;
Paired associates learning is impaired in both schizophrenia and amnestic mild cognitive impairment (aMCI), which may reflect hippocampal pathology.  ...  In aMCI, there were similar memory deficits for both types of stimuli. Orientation discrimination for M-and P-biased stimuli was intact in both groups of patients.  ...  Fig. 3 . 3 Correlation between right hippocampal volume (mm 3 ) and paired associates learning (number of errors) in patients with amnestic mild cognitive impairment (aMCI).  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.neuropsychologia.2012.10.010">doi:10.1016/j.neuropsychologia.2012.10.010</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/23085125">pmid:23085125</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/e5jf4ysferbotgyy63o33dozwe">fatcat:e5jf4ysferbotgyy63o33dozwe</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20180721121235/http://publicatio.bibl.u-szeged.hu/11395/1/Keri_Neuropsychol_2012.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/7a/13/7a137e230078a19b8a7f0e9d26660ba4bd3407f2.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.neuropsychologia.2012.10.010"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> elsevier.com </button> </a>

Current understanding of magnetic resonance imaging biomarkers and memory in Alzheimer's disease

Ece Bayram, Jessica Z.K. Caldwell, Sarah J. Banks
<span title="">2018</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/jjcnjbdwyvh6ldk6ktztp7xihy" style="color: black;">Alzheimer s &amp; Dementia Translational Research &amp; Clinical Interventions</a> </i> &nbsp;
As memory impairments are among the first symptoms of AD, the relationship between imaging findings and memory deficits is important in biomarker research.  ...  Atrophy in several frontal and parietal regions, cortical thinning, and white matter alterations correlate with memory deficits in early AD.  ...  Abbreviations: APOE ε4, apolipoprotein E ε4; CNC, cognitively normal control; aMCI, amnestic mild cognitive impairment; MCI, mild cognitive impair- ment; Table 4 4 Molecular MRI correlates of episodic  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.trci.2018.04.007">doi:10.1016/j.trci.2018.04.007</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/30229130">pmid:30229130</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC6140335/">pmcid:PMC6140335</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/hbt3h7q5hbdezohvltwvsi2arq">fatcat:hbt3h7q5hbdezohvltwvsi2arq</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200208224656/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC6140335&amp;blobtype=pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/85/05/8505c032234a4c0e784bff86148641efe2838cf5.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.trci.2018.04.007"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> elsevier.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140335" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Association between subfield volumes of the medial temporal lobe and cognitive assessments

Masayo Ogawa, Daichi Sone, Iman Beheshti, Norihide Maikusa, Kyoji Okita, Harumasa Takano, Hiroshi Matsuda
<span title="2019-06-04">2019</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/ifjemtdanzevfbtz3nv7p24qjm" style="color: black;">Heliyon</a> </i> &nbsp;
The aim of this study was to uncover which specific hippocampal subfields and adjacent extrahippocampal structures contribute to deficits in cognitive assessment scores in patients with MCI and AD.  ...  The Montreal Cognitive Assessment (MoCA) is reported to be more suitable than the Mini-Mental State Examination (MMSE) for screening mild cognitive impairment (MCI) and mild AD.  ...  Tenshou Yamao of the National Center of Neurology and Psychiatry for their support.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.heliyon.2019.e01828">doi:10.1016/j.heliyon.2019.e01828</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/31194147">pmid:31194147</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC6551380/">pmcid:PMC6551380</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/2dzb4qvyzvguvdzpcbmr7f3t5e">fatcat:2dzb4qvyzvguvdzpcbmr7f3t5e</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20210526094129/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC6551380&amp;blobtype=pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/cd/3b/cd3b60d71b1508a07aa3d2d40d23a946488dccc9.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.heliyon.2019.e01828"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> elsevier.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551380" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Episodic memory on the path to Alzheimer's disease

Michela Gallagher, Ming Teng Koh
<span title="">2011</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/k3yjoadbwjdifhgyc2nqlfzg2u" style="color: black;">Current Opinion in Neurobiology</a> </i> &nbsp;
The layer II neurons in the entorhinal cortex and their targets in the dentate gyrus and CA3 region of hippocampus comprise a system that rapidly encodes representations that are distinct from prior memories  ...  This review is focused on specific circuits of the medial temporal lobe that have become better understood in recent years for their computational properties contributing to episodic memory and to memory  ...  Acknowledgements This work was supported by a grant (P01-AG-09973) from the National Institute of Aging and the Senior Scholar Award from the Ellison Medical Foundation to Michela Gallagher.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.conb.2011.10.021">doi:10.1016/j.conb.2011.10.021</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/22079495">pmid:22079495</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3254732/">pmcid:PMC3254732</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/lkxopcjq45fgxmmd6lna7g3hsu">fatcat:lkxopcjq45fgxmmd6lna7g3hsu</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20150630092248/http://neuroscience.jhu.edu/uploads/publications/Gallagher_M/1-s2_0-S0959438811001875-main.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/9b/26/9b26447e79c2027a76bd9c9632e9cede9ccac33d.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.conb.2011.10.021"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> elsevier.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3254732" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Structural imaging of hippocampal subfields in healthy aging and Alzheimer's disease

Robin de Flores, Renaud La Joie, Gaël Chételat
<span title="">2015</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/l52eh66fdzhhbmbsefbbyzwkaq" style="color: black;">Neuroscience</a> </i> &nbsp;
Preliminary studies have indicated that looking at this focal atrophy pattern rather than standard whole hippocampus volumetry improves diagnostic accuracy at the Mild Cognitive Impairment (MCI) stage.  ...  Highlights: -Hippocampal subfield structure can be assessed in vivo with (high-resolution) MRI -AD-related atrophy is initially focal (in CA1) before spreading to other subfields -This pattern of atrophy  ...  (Sarazin et al., 2010) ; and ii) impaired recognition performances, likely reflecting encoding deficits in amnestic MCI patients (Fouquet et al., 2012) .  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.neuroscience.2015.08.033">doi:10.1016/j.neuroscience.2015.08.033</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/26306871">pmid:26306871</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/mo2oypyj4vhyhgow7nznti3wx4">fatcat:mo2oypyj4vhyhgow7nznti3wx4</a> </span>
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