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Rintact: enabling computational analysis of molecular interaction data from the IntAct repository

T. Chiang, N. Li, S. Orchard, S. Kerrien, H. Hermjakob, R. Gentleman, W. Huber
2007 Bioinformatics  
Motivation: The IntAct repository is one of the largest and most widely used databases for the curation and storage of molecular interaction data.  ...  Results: We introduce Rintact, a Bioconductor package that allows users to transform PSI-MI XML2.5 interaction data files from IntAct into R graph objects.  ...  ACKNOWLEDGEMENTS We would like to thank Abhishek Pratap and Li Wang for testing the Rintact software package.  ... 
doi:10.1093/bioinformatics/btm518 pmid:17989096 fatcat:i74o7n7hbnfofg7hwgjc5wtmli

Fundamentals of protein interaction network mapping

J. Snider, M. Kotlyar, P. Saraon, Z. Yao, I. Jurisica, I. Stagljar
2015 Molecular Systems Biology  
Studying protein interaction networks of all proteins in an organism ("interactomes") remains one of the major challenges in modern biomedicine.  ...  In addition, we discuss computational methods to predict, map, and visualize interactomes, and provide a summary of some of the most important interactome resources.  ...  The work in the Stagljar laboratory is supported by grants from the Ontario Genomics  ... 
doi:10.15252/msb.20156351 pmid:26681426 pmcid:PMC4704491 fatcat:yl45k4mjrrdv5m7lzxyfinkknm