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Rich Club Organization and Cognitive Performance in Healthy Older Participants
2015
Journal of Cognitive Neuroscience
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in healthy participants and whether the rich club might be differentially involved in cognitive functions with a heavier dependence on global integration. ...
With a putative "rich club" of hubs hypothesized to play a central role in global integrative brain functioning, we assessed whether hub and rich club organizations are associated with cognitive performance ...
Here, we investigated the role of the rich club in cognitive performance in a sample of healthy older participants. ...
doi:10.1162/jocn_a_00821
pmid:25941870
fatcat:uo2acd4wfzfvdjbhzymonoyt7i
Rich-Club Connectivity of the Structural Covariance Network Relates to Memory Processes in Mild Cognitive Impairment and Alzheimer's Disease
2022
Journal of Alzheimer's Disease
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Objective: To investigate how the cortical brain organization is altered in AD we studied the mutual connectivity of hubs in the SCN, i.e., the rich-club. ...
Subsequently, rich-club coefficients were calculated from the SCN, and related to memory performance and hippocampal volume using linear regression. ...
For example, the extent of rich-club configuration in the anatomical network has been associated to cognitive performance in healthy participants using diffusion tensor imaging [21], and more recently ...
doi:10.3233/jad-220175
pmid:35871335
fatcat:6lysiacg2vdeth4fwkhtqvvpoi
Longitudinal changes in rich club organization and cognition in cerebral small vessel disease
2019
NeuroImage: Clinical
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Here we examined the progression of disturbances in rich club organization in older adults with SVD and their associations with conventional SVD markers and cognitive decline. ...
SVD-related disturbances in rich club organization progressed over time, predominantly in participants with severe SVD. ...
Effects of rich club organization on cognitive performance The results from linear regression analyses on the associations between longitudinal changes in rich club organization and cognitive decline are ...
doi:10.1016/j.nicl.2019.102048
pmid:31706220
pmcid:PMC6978216
fatcat:6f2biq2y5bf3rhq6vc2qtb4wr4
Abnormal Rich Club Organization of Structural Network as a Neuroimaging Feature in Relation With the Severity of Primary Insomnia
2020
Frontiers in Psychiatry
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We examined alterations in brain rich-club organization as revealed by diffusion tensor imaging (DTI) and the statistical relationships between abnormalities in rich-club metrics and the clinical features ...
Aberrant rich-club organization was found mainly in limbic-cortical-basal ganglia circuits and the default-mode network. ...
Rich Club Organization According by previous studies (9, 11) , rich club organizations were identified in structural networks from WM by averaging-group matrix in all participants of each group with a ...
doi:10.3389/fpsyt.2020.00308
pmid:32390883
pmcid:PMC7190795
fatcat:oqr2os6xibcizpguvzcnrzzmfa
Alterations in structural rich-club connectivity of the precuneus are associated with depressive symptoms among individuals with subjective memory complaints
2018
Cognitive, Affective, & Behavioral Neuroscience
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Because rich-club organization of the brain plays a key role in the pathophysiology of various neuropsychiatric disorders, the investigation of rich club organization may provide insight regarding the ...
For all participants, high-resolution, T1-weighted images and diffusion tensor images were obtained, and the network analysis was performed. ...
rich-club organizations. ...
doi:10.3758/s13415-018-0645-x
pmid:30298425
fatcat:pg6cno4ihjgmnoly7gjhy56jty
Reorganized Brain Functional Network Topology in Presbycusis
2022
Frontiers in Aging Neuroscience
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sex-, and education-matched healthy controls. ...
Graph theory was applied to analyze the topological properties of brain functional networks including global and nodal metrics, modularity, and rich-club organization.ResultsAt the global level, the brain ...
FIGURE 4 | 4 FIGURE 4 | The rich-club organization for presbycusis patients with cognitive decline, presbycusis patients without cognitive decline, and healthy controls. ...
doi:10.3389/fnagi.2022.905487
pmid:35693344
pmcid:PMC9177949
fatcat:y4ppyke6jzfy7leqhpr25p6e2e
The effect of external stimulation on functional networks in the aging healthy human brain
[article]
2021
bioRxiv
pre-print
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We found that the precuneus, a brain area belonging to the default mode network and the rich club, was the best stimulation target. ...
Then, we fitted the PMS to a whole-brain model and applied in silico stimulations with different intensities in each node to force transitions from the brain states of the older group to the middle-age ...
Acknowledgments AE, YS and GD were supported by the HBP SGA3 Human Brain Project Specific Grant Agreement 3 (grant agreement no. 945539), funded by the EU H2020 FET Flagship. ...
doi:10.1101/2021.11.19.469206
fatcat:e6n36xbohzggxnksl5t6ijbjim
Selective vulnerability of Rich Club brain regions is an organizational principle of structural connectivity loss in Huntington's disease
2015
Brain
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The 'rich club' is a pattern of organization established in healthy human brains, where specific hub 'rich club' brain regions are more highly connected to each other than other brain regions. ...
Consistent with our hypothesis we found that structural connectivity loss selectively affected rich club brain regions in premanifest and manifest Huntington's disease participants compared with controls ...
We would also like to thank James Mills for his input in the statistical analysis and Ray Young for his assistance with the figures/tables. ...
doi:10.1093/brain/awv259
pmid:26384928
pmcid:PMC4620513
fatcat:otoqxfooanbstn5x5unktkygl4
Trajectory of rich club properties in structural brain networks
[article]
2021
bioRxiv
pre-print
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Rich club organization has been shown to be highly beneficial for communicability and higher cognition. ...
A resilient rich club might thus be protective of a functional loss in late adulthood and represent a neural reserve to sustain cognitive functioning in the aging brain. ...
It has, for instance, been shown that stronger rich club organization in middle and late adulthood relates to better performance in cognitive domains (Baggio et al., 2015) . ...
doi:10.1101/2021.11.16.468806
fatcat:ooi6d3zvufggtecpl6qfffmw7y
Weight Rich-Club Analysis in the White Matter Network of Late-Life Depression with Memory Deficits
2017
Frontiers in Aging Neuroscience
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We found that compared with HC participants, patients with LLD (LLD-MD and LLD-IM) had relatively impaired rich-club organizations and rich-club connectivity. ...
In conclusion, the disease effects of LLD were prevalent in rich-club organization. ...
In the current study, positive assortativity was found in all participants. In addition, LLD patients have lower assortativity than HC, which was consistent with our rich-club organization findings. ...
doi:10.3389/fnagi.2017.00279
pmid:28878666
pmcid:PMC5572942
fatcat:52sl5yoqtzahda3ynabz2shoci
Brain network analysis reveals affected connectome structure in bipolar I disorder
2015
Human Brain Mapping
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club' organization. ...
'rich club' system appears not to be particularly affected. ...
for Education and Research (UPPER)' for their assistance in recruiting participants. ...
doi:10.1002/hbm.23017
pmid:26454006
pmcid:PMC5597048
fatcat:6nh7pm54bzhutckryt23nf36xy
Aberrant Rich Club Organization in Patients with Obsessive-Compulsive Disorder and Their Unaffected First-Degree Relatives
2021
NeuroImage: Clinical
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We examined the structural rich club organization and its interrelationship with functional coupling. ...
Recent studies suggested that the rich club organization promoting global brain communication and integration of information, may be abnormally increased in obsessive-compulsive disorder (OCD). ...
Acknowledgment This study was partly supported by National Natural Science Foundation of China (31871113, 31920103009, 32071049, 31900770 and 31671135). ...
doi:10.1016/j.nicl.2021.102808
pmid:34500426
pmcid:PMC8430383
fatcat:glhhe3q5yfb4dhyt3du6agtxqu
Rich-Club Analysis of Structural Brain Network Alterations in HIV Positive Patients With Fully Suppressed Plasma Viral Loads
2022
Frontiers in Neurology
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Rich-club analysis was used to identify hub nodes across groups and abnormal rich-club connections. ...
alterations and cognitive impairment. ...
cognitive performance and clinical variables. ...
doi:10.3389/fneur.2022.825177
pmid:35812120
pmcid:PMC9263507
fatcat:57hq3ih5hvfc7pkzfexybmoyl4
The Organisation of the Elderly Connectome
[article]
2015
arXiv
pre-print
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Here, whole-brain probabilistic tractography was performed on high-angular diffusion-weighted images acquired from 115 healthy elderly subjects, whom were 76 to 94 years old. ...
These findings provide insights into healthy brain ageing and provide a benchmark for the study of neurodegenerative disorders such as Alzheimers disease and Frontotemporal Dementia. ...
Structural and functional aspects relating to cost and benefit of rich club organization in the human cerebral cortex. Cereb Cortex 24, 2258-2267. ...
arXiv:1502.05772v2
fatcat:rgcl3ufxavdm7iuvok5kanzdqa
Fostering Well-Being in the Elderly: Translating Theories on Positive Aging to Practical Approaches
2021
Frontiers in Medicine
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Drawing upon positive psychology and positive aging research and tools, this program is designed to help older adults improve their well-being by acquiring skills and strategies to cope with present and ...
It can easily be conducted in wide range of adult education programs in community centers, sheltered homes, and primary care clinics. ...
Interventions in healthy older adults such as physical or dietary changes and enhancing social and cognitive engagement can help diminish the impact of loneliness on the aging process and the emergence ...
doi:10.3389/fmed.2021.517226
pmid:33898472
pmcid:PMC8062922
fatcat:hfjyrwn63nhghkb56ln7xvkijq
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