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Reprint of "Pharmacokinetic modelling of the anti-malarial drug artesunate and its active metabolite dihydroartemisinin"

Adam J. Hall, Michael J. Chappell, John A.D. Aston, Stephen A. Ward
2014 Computer Methods and Programs in Biomedicine  
profiles of 19 malaria patients.  ...  Initial validation of the model under various combinations of the constraints leading to identifiable model structures was performed against a dataset of artesunate and dihydroartemisinin concentration-time  ...  The authors would like to thank Dr Abhishek Srivastava at the Department of Parasitology at the Liverpool School of Tropical Medicine for assaying the samples, and the patients who all gave written informed  ... 
doi:10.1016/j.cmpb.2013.12.001 pmid:24457047 fatcat:7svpt3nshzaedjjfyc4qt5bv6u