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Releasing fast and slow: an exploratory case study at ING

Elvan Kula, Ayushi Rastogi, Hennie Huijgens, Arie van Deursen, Georgios Gousios
2019 Proceedings of the 2019 27th ACM Joint Meeting on European Software Engineering Conference and Symposium on the Foundations of Software Engineering - ESEC/FSE 2019  
This paper presents an exploratory case study of rapid releases at ING, a large banking company that develops software solutions in-house, to characterize rapid releases.  ...  Since 2011, ING has shifted to a rapid release model. This switch has resulted in a mixed environment of 611 teams releasing relatively fast and slow.  ...  Study Design We conducted an exploratory case study [13] of rapid releases at ING with two units of analysis: the group of rapid teams and the group of non-rapid teams.  ... 
doi:10.1145/3338906.3338978 dblp:conf/sigsoft/KulaRHDG19 fatcat:x6o6ihcmundizdtkd6qylqqfci

SCN10A Mutation in a Patient with Erythromelalgia Enhances C-Fiber Activity Dependent Slowing

Andreas M. Kist, Dagrun Sagafos, Anthony M. Rush, Cristian Neacsu, Esther Eberhardt, Roland Schmidt, Lars Kristian Lunden, Kristin Ørstavik, Luisa Kaluza, Jannis Meents, Zhiping Zhang, Thomas Hedley Carr (+10 others)
2016 PLoS ONE  
The p.M650K mutation shifted steady-state fast inactivation of Nav1.8 to more hyperpolarized potentials and did not significantly alter any other tested gating behaviors.  ...  Recordings of the patient's peripheral nerve fibers showed increased activity dependent slowing (ADS) in CMi and less spontaneous firing compared to a control group of erythromelalgia patients without  ...  Recovery from fast inactivation as determined by an increasing inter-pulse interval at -120 mV and at -70 mV for periods between 1 ms and 512 ms did not reveal any significant changes induced by the M650K  ... 
doi:10.1371/journal.pone.0161789 pmid:27598514 pmcid:PMC5012686 fatcat:zqqoq5psibfzfd55twbr3sph6e

Clustering of Ca 2+ transients in interstitial cells of Cajal defines slow wave duration

Bernard T. Drumm, Grant W. Hennig, Matthew J. Battersby, Erin K. Cunningham, Tae Sik Sung, Sean M. Ward, Kenton M. Sanders, Salah A. Baker
2017 The Journal of General Physiology  
Ca 2+ transients in ICC-MY display a complex firing pattern caused by localized Ca 2+ release events arising from multiple sites in cell somata and processes.  ...  These Ca 2+ transients are caused by Ca 2+ release from intracellular stores and depend on ryanodine receptors as well as amplification from IP 3 receptors.  ...  This project was supported by exploratory research funding from the University of Nevada and NID DK grant P01 DK41315.  ... 
doi:10.1085/jgp.201711771 pmid:28592421 pmcid:PMC5496507 fatcat:lv6shdtiwfbkhkkbocqkarjfsq

Using the movement patterns of reintroduced animals to improve reintroduction success

Oded Berger-TAL, David Saltz
2014 Current Zoology  
trade-off that released animals go through, and which underlies their behavior.  ...  Reintroduced animals are released into unfamiliar novel environments and must explore their surroundings to gain knowledge in order to survive.  ...  This study was funded by an Israel Science Foundation (ISF) grant 1397/10 and by the Israel Nature and Park Authority. We thank R. King and A.  ... 
doi:10.1093/czoolo/60.4.515 fatcat:dl47lpi2ujgfdljodg6wcyr4r4

Presynaptic Specificity of Endocannabinoid Signaling in the Hippocampus

Rachel I. Wilson, George Kunos, Roger A. Nicoll
2001 Neuron  
by their fast kinetics and large unitary conductance.  ...  Endocannabinoids are thought to mediate the suppression of GABA release that follows expression (Pitler and Alger, 1992; Alger et al., 1996; Morishita and Alger, 1997), an absolute requirement for depolarization  ...  We termed these two groups "GABA-A fast " and "GABA-A slow ," following the convention established by a previous study (Pearce, 1993).  ... 
doi:10.1016/s0896-6273(01)00372-5 pmid:11516401 fatcat:r2n7ov5vrjb4xc2elnmo4b3pz4

Towards a Comprehensive Catalog of Zebrafish Behavior 1.0 and Beyond

Allan V. Kalueff, Michael Gebhardt, Adam Michael Stewart, Jonathan M. Cachat, Mallorie Brimmer, Jonathan S. Chawla, Cassandra Craddock, Evan J. Kyzar, Andrew Roth, Samuel Landsman, Siddharth Gaikwad, Kyle Robinson (+17 others)
2013 Zebrafish  
rerio) are rapidly emerging as a useful species for studying normal or pathological behaviors 4-10 and modeling complex brain disorders 11-17 (Table 1 ).  ...  Novel zebrafish paradigms continue to appear with an encouraging pace, thus necessitating a consistent terminology and improved understanding of the behavioral repertoire.  ...  Diving is an active, fast and directed zebrafish behavior (with body heading towards the bottom head first); differs from passive, more slow and undirected behaviors, such as sinking or Cartesian diver  ... 
doi:10.1089/zeb.2012.0861 pmid:23590400 pmcid:PMC3629777 fatcat:omhnc3o6nfcvlnvidtifhhzwxu

Experimental Observations on Hypertonus*

2008 Developmental Medicine & Child Neurology  
Many of these ‘ tonic’ moto- neurones are connected to slow muscles. In baby kittens all the muscles are slow, and during maturation some of them become fast.  ...  The posi- tive behaviour is exploratory in type (the positive supporting reaction in the lower limb, grasping in the upper limb, and suck- ing), and the negative behaviour is an avoiding or withdrawal  ... 
doi:10.1111/j.1469-8749.1959.tb08080.x fatcat:vpdfntuwsbeenmshbpo4wvmh3u

Dynamic properties of mammalian skeletal muscles

R I Close
1972 Physiological Reviews  
There are at least two possible interpretations of the differences in activation of fast and slow muscles that have been revealed by studies of PTP.  ...  fast and slow muscle, respectively ( 139)) and 2.8 for mixed fast and slow muscle of the rat (438), all measurements having been made at room temperature and in similar conditions of stirring.  ... 
doi:10.1152/physrev.1972.52.1.129 pmid:4256989 fatcat:y2kzmyfhhbdo5cvqx7wxqfjpze

Feasibility of Double-Blind Clinical Trials with Oral Diacetylmorphine: A Randomized Controlled Phase II Study in an Inpatient Setting

Joan Colom Farran, Miguel Casas, José Pérez de los Cobos, Miquel del Río, Carlos Roncero, Xavier Castells, Sergi Valero, Francisco José Eiroa-Orosa, Francisca Batlle, Joan Trujols
2012 European Addiction Research  
This was a randomized, phase II, double-blind, multicenter pilot study comparing immediate-release oral DAM, slow-release oral morphine and oral methadone administered twice a day during 10 days.  ...  Patients were stabilized with a mean of 350 mg (SD = 193) of immediate-release oral DAM, 108 mg (SD = 46.2) of slow-release oral morphine and  ...  study.  ... 
doi:10.1159/000336849 pmid:22854605 fatcat:g3gqsvxabrd2bi6vsttnqhjg5m

Page 1430 of JAMA: The Journal of the American Medical Association Vol. 120, Issue 17 [page]

1942 JAMA: The Journal of the American Medical Association  
The ideal method is to provide a slow, steady release of hormone all day, a result which is best achieved by pellet implantation.  ...  Determination of the fasting plasma ascorbic acid is the simplest and most direct exploratory objective method in detecting subclinical vitamin C deficiency or scurvy.  ... 

Individual variation in age‐dependent reproduction: fast explorers live fast but senesce young?

Niels J. Dingemanse, Maria Moiron, Yimen G. Araya‐Ajoy, Alexia Mouchet, Robin N. Abbey‐Lee
2019 Journal of Animal Ecology  
varied with exploratory behaviour.  ...  Slower and faster explorers produced moderate-sized clutches when young; faster explorers subsequently showed an increase in clutch size that diminished with age (with moderate support for declines when  ...  bill and wing length) and a blood sample taken, and the bird released (within 15 min post-capture).  ... 
doi:10.1111/1365-2656.13122 pmid:31618450 fatcat:dnkdtapadff65gd3hxrjbiougi

AI Lifecycle Models Need To Be Revised. An Exploratory Study in Fintech [article]

Mark Haakman, Luís Cruz, Hennie Huijgens, Arie van Deursen
2021 arXiv   pre-print
We conducted an exploratory case study at ING, a global bank with a strong European base. We interviewed 17 people with different roles and from different departments within the organization.  ...  This study aims to understand the processes by which artificial intelligence-based systems are developed and how state-of-the-art lifecycle models fit the current needs of the industry.  ...  The authors would also like to thank all the participants of the interviews at ING.  ... 
arXiv:2010.02716v2 fatcat:5jdwun5e3zaxlpllfybbfl6uem

From lamprey to salamander: an exploratory modeling study on the architecture of the spinal locomotor networks in the salamander

Andrej Bicanski, Dimitri Ryczko, Jean-Marie Cabelguen, Auke Jan Ijspeert
2013 Biological cybernetics  
Here we present sic frequencies can be coupled together and produce phase an exploratory study on the salamander axial CPG architec- locked activity.  ...  Biol Cybern (2013) 107:565–587 DOI 10.1007/s00422-012-0538-y ORIGINAL PAPER From lamprey to salamander: an exploratory modeling study on the architecture of the spinal locomotor networks in the salamander  ... 
doi:10.1007/s00422-012-0538-y pmid:23463500 fatcat:dmauloteova4rhsieq5fyhpnle

A CLINICAL EVALUATION OF METHOXYFLURANE IN MAN

F. ARTUSIO JOSEPH, ALAN VAN POZNAK, E. HUNT RICHARD, M. TIERS FRANCIS, MANFRED ALEXANDER
1960 Anesthesiology  
The prolonged emer- gence is probably due to the high fat solubility with subsequent slow release of the agent into the blood, thus maintaining an anesthetic con- centration in the brain.  ...  This electroencephalographic pattern was un- like that characteristic of diethyl ether, since an immediate transition from fast activity of low voltage to slow activity of high voltage TABLE 2 COMPARISON  ... 
doi:10.1097/00000542-196009000-00009 fatcat:xpvdtjponjerdpcouwsileqkae

Challenges of Adopting SAFe in the Banking Industry – A Study Two Years after its Introduction [article]

Sara Nilsson Tengstrand, Piotr Tomaszewski, Markus Borg, Ronald Jabangwe
2021 arXiv   pre-print
To fill this gap, we present a study on the main challenges with a SAFe transformation at a large full-service bank.  ...  We identify the challenges in the bank under study and compare the findings with experience reports from other banks, as well as with research on SAFe transformations in other domains.  ...  The study is exploratory since it seeks new insights into the SAFe transformation challenges in the case company and the banking industry in general. Method Fig. 3.  ... 
arXiv:2104.13992v1 fatcat:vw3gupncovaafj7rf7nrtkdqju
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