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Computer-aided design of amino acid-based therapeutics: a review

Tayebeh Farhadi, Seyed MohammadReza Hashemian
2018 Drug Design, Development and Therapy  
The redesign of a procarboxypeptidase Computational protein design protocol RosettaDesign was used to completely redesign the sequence of the activation domain of human procarboxypeptidase A2 Yielding  ...  make testable predictions and refine design hypotheses.  ... 
doi:10.2147/dddt.s159767 pmid:29795978 pmcid:PMC5958949 fatcat:mkd3acifezhb3cq2pfdo2ngxb4

From the Editor-in-Chief

Kimon P. Valavanis
2018 Journal of Intelligent and Robotic Systems  
Acknowledgement We thank Mrs Christiane Gauvin for secretarial assistance, Acknowledgement The author is indebted to many colleagues and friends for the active discussions and exchanges both in the  ...  Acknowledgement The work was partly supported by the grant number  ...  processing means in order to feed, refine and evaluate the relevance of model and the most plausible interpretations.  ... 
doi:10.1007/s10846-018-0847-z fatcat:zg6ye677mbgxvfxhlqw35n7ega

Export Signals [chapter]

2008 Encyclopedia of Genetics, Genomics, Proteomics and Informatics  
and predicted proteomes with cross-links to protein structure and statistical analysis: http://www.ebi.ac.  ...  The sequenced circular genome of this soil bacterium comprises 8,212,805 base pairs and predicted to encode 7,264 genes (see Fig. E47).  ...  : Export adaptors are proteins which attach to proteins of RNAs and assist their export or import, respectively, between nucleus and cytoplasm.  ... 
doi:10.1007/978-1-4020-6754-9_5734 fatcat:6qstuftdi5dhnbuulcl4m6nfme

Ecology [chapter]

James C. Dunford, Louis A. Somma, David Serrano, C. Roxanne Rutledge, John L. Capinera, Guy Smagghe, Eli Shaaya, David G. Riley, John L. Capinera, Steve H. Dreistadt, Susanne D. Dyby, John B. Heppner (+24 others)
2008 Encyclopedia of Entomology  
and predicted proteomes with cross-links to protein structure and statistical analysis: http://www.ebi.ac.  ...  The sequenced circular genome of this soil bacterium comprises 8,212,805 base pairs and predicted to encode 7,264 genes (see Fig. E47).  ...  : Export adaptors are proteins which attach to proteins of RNAs and assist their export or import, respectively, between nucleus and cytoplasm.  ... 
doi:10.1007/978-1-4020-6359-6_3494 fatcat:zdm7o5n7jngerpge54q4mmczme

Application of traditional and innovative techniques to investigate productive efficiency and related molecular traits in broiler chickens

Marco Zampiga
2019
For each rPCA model, the scoreplot, that is the projection of the samples in the PC space tailored to highlight the underlying structure of the data, was calculated.  ...  HA birds showed a greater expression of gene sets related to cellular energy production, mitochondria structure and functionality, as well as cell structure and integrity, ribosome structure and assembly  ...  1.5% of the body weight (Spratt et al., 1990) . The upregulation of pathways related to mitochondria structure (e.g.  ... 
doi:10.6092/unibo/amsdottorato/9002 fatcat:gj4lrm6jevcmhfqbjw23vfe3fm

Potential of high isostatic pressure and pulsed electric fields for the processing of potato and pea proteins [article]

Anne Kathrin Baier, Technische Universität Berlin, Technische Universität Berlin, Dietrich Knorr
2016
Induced changes in protein solutions and plant tissue of potato and pea were analyzed by means of structural and techno-functional characterization as well as by investigation of diffusion and extractions  ...  Protein concentrates with unique functional properties and flours with modified starch digestibility could be produced by the application of high pressure.  ...  Understanding the relationship between structure and functionality could help to predict the behaviour of protein products in various applications and different media.  ... 
doi:10.14279/depositonce-4985 fatcat:oe5rdohpfjamhcyc352stbcpg4

Machine perfusion for assessing and optimizing kidney and pancreas allografts

Karim Hamaoui, Vassilios Papalois, Ara Darzi, Nagy Habib, Imperial College Healthcare Charity, Live Life Give Life
2017
Using HMP and normothermic-reperfusion models of porcine and human kidney and pancreatic grafts, this project has investigated strategies addressing these themes.  ...  Separately the application of a novel adenosine/lidocaine based preservation solution in renal HMP preservation can potentially ameliorate reperfusion injury seen using conventional solutions.  ...  of promising initial data in the porcine model, application of these HMP techniques to unused human grafts is necessary.  ... 
doi:10.25560/55177 fatcat:h3kgfjztsfdk7dlppxowxvkm6u