A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2017; you can also visit the original URL.
The file type is application/pdf.
Filters
Reconstructing latent periods in genome sequences with insertions and deletions
2009
2009 IEEE International Workshop on Genomic Signal Processing and Statistics
Preserved Fulltext
This reconstructs likely insertions and deletions in the sequence and results in better estimates of the statistical period and cyclostationary profiles than the ML approach. ...
Tandem and latent repeats in genome sequences provide insight into its various structural and functional roles. ...
An iterative algorithm is proposed for recovering latent periods by reconstructing likely insertions and deletions in the ancestral cyclostationary sequence. ...
doi:10.1109/gensips.2009.5174377
dblp:conf/gensips/AroraDS09
fatcat:ngtsmnqarzdj7cstz6lf4dpdcm
Alterations in the U3 region of the long terminal repeat of an infectious thymotropic type B retrovirus
1988
Journal of Virology
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is application/pdf.
a very short latent period. ...
Nucleotide sequence studies confirmed these results and showed that in this region 440 nucleotides of the MMTV (C3H) sequences were deleted and substituted with a segment of 122 nucleotides. ...
a very short latent period. ...
doi:10.1128/jvi.62.8.2985-2993.1988
fatcat:hzrqsdpb2jchbatbi32rtlfs3i
Alterations in the U3 region of the long terminal repeat of an infectious thymotropic type B retrovirus
1988
Journal of Virology
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is application/pdf.
a very short latent period. ...
Nucleotide sequence studies confirmed these results and showed that in this region 440 nucleotides of the MMTV (C3H) sequences were deleted and substituted with a segment of 122 nucleotides. ...
a very short latent period. ...
pmid:2839715
pmcid:PMC253737
fatcat:6mg65acimvhwrasbvv67y2ae4m
Higher genome mutation rates of Beijing lineage of Mycobacterium tuberculosis during human infection
2020
Scientific Reports
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2021; you can also visit the original URL.
The file type is application/pdf.
We sequenced genomes of these isolates and analyzed the propensity and rate of genomic mutations. Generation time versus mutation rate curves were significantly higher for RP. ...
The ratio of oxidative versus non-oxidation damages induced mutations was higher in SP than RP, suggesting that persistent Mtb are exposed to oxidative stress in the latent state. ...
The funders had no role in study design, data collection and interpretation, or the decision to submit the wok for publication. ...
doi:10.1038/s41598-020-75028-2
pmid:33093577
fatcat:sdosyrrdujbgdnzvljybjjs5eq
Delimitation of essential genes of cassava latent virus DNA 2
1988
Nucleic Acids Research
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2019; you can also visit the original URL.
The file type is application/pdf.
Insertion and deletion mutagenesis of both extended open reading frames (ORFs) of cassava latent virus DNA 2 destroys infectivity. ...
By cloning specific fragments into DNA 1 coat protein deletion vectors we have delimited the DNA 2 coding regions and provide substantive evidence that both are essential for virus infection. ...
Sequence analysis showed that the leader sequence was deleted up to, but not including, nucleotide 581 in pJSl95. ...
doi:10.1093/nar/16.11.4811
pmid:3387209
pmcid:PMC336698
fatcat:nvx6vmwlhvbqvo4bosqlxpelh4
Replication-Competent Noninduced Proviruses in the Latent Reservoir Increase Barrier to HIV-1 Cure
2013
Cell
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2017; you can also visit the original URL.
The file type is application/pdf.
Alireza Rabi, Gregory Laird, and Drs. Stuart ...
Noninduced proviruses included those with intact genomes (red bars), insertions or deletions (blue bars), and hypermutation (white bars). ...
Left to right: intact genome, 16 bp J deletion, deletion with defined junction, and deletion with undefined junction. Clone name is given below each gel. ...
doi:10.1016/j.cell.2013.09.020
pmid:24243014
pmcid:PMC3896327
fatcat:xgxi3nwocba6lhvmqx4hi6oay4
Detection of herpes simplex virus-specific DNA sequences in latently infected mice and in humans
1986
Journal of Virology
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is application/pdf.
Herpes simplex virus-specific DNA sequences have been detected by Southern hybridization analysis in both central and peripheral nervous system tissues of latently infected mice. ...
This "endless" herpes simplex virus DNA is both qualitatively and quantitatively stable in mouse neural tissue analyzed over a 4-month period. ...
S.E. holds a Cooperative Award in Science and Engineering supported by the Wellcome Foundation Ltd. J.R.A. is in receipt of a grant from the East Anglia Regional Health Authority.
LITERATURE CITED ...
doi:10.1128/jvi.57.2.446-455.1986
fatcat:qjbweliwobcmfaynzvmtzopqfy
Detection of herpes simplex virus-specific DNA sequences in latently infected mice and in humans
1986
Journal of Virology
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is application/pdf.
Herpes simplex virus-specific DNA sequences have been detected by Southern hybridization analysis in both central and peripheral nervous system tissues of latently infected mice. ...
This "endless" herpes simplex virus DNA is both qualitatively and quantitatively stable in mouse neural tissue analyzed over a 4-month period. ...
S.E. holds a Cooperative Award in Science and Engineering supported by the Wellcome Foundation Ltd. J.R.A. is in receipt of a grant from the East Anglia Regional Health Authority.
LITERATURE CITED ...
pmid:3003377
pmcid:PMC252756
fatcat:c24lwv5qyndpvkbx3cm4tbpu2e
Identifying Likely Transmission Pathways within a 10-Year Community Outbreak of Tuberculosis by High-Depth Whole Genome Sequencing
2016
PLoS ONE
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2017; you can also visit the original URL.
The file type is application/pdf.
Whole genome sequencing, with analysis of single-nucleotide polymorphisms, insertions, deletions, structural variants and subpopulations, enabled the highest possible level of discrimination between cluster ...
In addition to single-nucleotide polymorphisms, the analyses also sought to identify insertions, deletions and structural variants. ...
We are also grateful to Chris Lowbridge, Tracie Reinten and Vicky Sheppeard, from Health Protection NSW, and to Michael Roper for valuable advice and technical support. ...
doi:10.1371/journal.pone.0150550
pmid:26938641
pmcid:PMC4777479
fatcat:wbyccnnyaffuzjk5q6utpo4icq
Mapping of the gene coding for Epstein-Barr virus-determined nuclear antigen EBNA3 and its transient overexpression in a human cell line by using an adenovirus expression vector
1987
Journal of Virology
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is application/pdf.
The expressed protein had the same molecular weight, subcellular localization, and immunological characteristics as the EBV-determined nuclear antigen EBNA3, which is made in lymphocytes latently infected ...
The T2 cDNA contains viral genomic sequences from the short BLRF3 open reading frame fused to the adjacent BERF1 long open reading frame. ...
The equivalent of the T2 cDNA sequence was reconstructed (for technical ease) by using the 5' region from the cDNA and the intron-free 3' region from the viral genome (Fig. 2) . ...
pmid:3041055
pmcid:PMC255922
fatcat:tzxdibnpzfdwrd243e2h4dxraq
Mapping of the gene coding for Epstein-Barr virus-determined nuclear antigen EBNA3 and its transient overexpression in a human cell line by using an adenovirus expression vector
1987
Journal of Virology
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is application/pdf.
The expressed protein had the same molecular weight, subcellular localization, and immunological characteristics as the EBV-determined nuclear antigen EBNA3, which is made in lymphocytes latently infected ...
The T2 cDNA contains viral genomic sequences from the short BLRF3 open reading frame fused to the adjacent BERF1 long open reading frame. ...
The equivalent of the T2 cDNA sequence was reconstructed (for technical ease) by using the 5' region from the cDNA and the intron-free 3' region from the viral genome (Fig. 2) . ...
doi:10.1128/jvi.61.10.3340-3344.1987
fatcat:vdow3fqmdrbofchqljku6obfry
Mapping genetic elements of Epstein-Barr virus that facilitate extrachromosomal persistence of Epstein-Barr virus-derived plasmids in human cells
1985
Molecular and Cellular Biology
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2019; you can also visit the original URL.
The file type is application/pdf.
A small in-frame deletion and linker insertion mutation in the region encoding the carboxy-terminal portion of EBNA-1, which replaced 19 amino acid codons with 2, had no effect on the maintenance of p410 ...
Two mutations in the BamHI-K-derived portion of p410+, a large in-frame deletion and a linker insertion frameshift mutation, both of which alter the carboxy-terminal portion of EBNA-1, destroyed the ability ...
We thank Noel Mann for help in preparing the manuscript. This work was supported by grants M47E and M47F from the American Cancer Society. ...
doi:10.1128/mcb.5.10.2533
pmid:3016506
pmcid:PMC366987
fatcat:v4okejo3vjdu5oa3mgnbiyvf5e
Molecular and biological properties of BK virus-IR, a BK virus variant isolated from a human tumor
1986
Journal of Virology
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is application/pdf.
BKV-IR bears a 253-base-pair (bp) deletion and an 80-bp insertion in the early region of the genome. The deletion abolishes the expression of small-t antigen. ...
As compared with wild-type BKV, BKV-IR transformed hamster cells with a reduced efficiency and induced ependymomas in hamsters at a lower frequency and with a longer latency period. ...
To better characterize the genome of BKV-IR, we carried out a nucleotide sequence analysis of the regions of BKV-IR DNA containing the insertion and the deletion and compared them with the corresponding ...
doi:10.1128/jvi.59.2.500-505.1986
fatcat:fdpxbymyyvcmfdbq4z7w4lu3ca
Molecular and biological properties of BK virus-IR, a BK virus variant isolated from a human tumor
1986
Journal of Virology
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is application/pdf.
BKV-IR bears a 253-base-pair (bp) deletion and an 80-bp insertion in the early region of the genome. The deletion abolishes the expression of small-t antigen. ...
As compared with wild-type BKV, BKV-IR transformed hamster cells with a reduced efficiency and induced ependymomas in hamsters at a lower frequency and with a longer latency period. ...
To better characterize the genome of BKV-IR, we carried out a nucleotide sequence analysis of the regions of BKV-IR DNA containing the insertion and the deletion and compared them with the corresponding ...
pmid:3016311
pmcid:PMC253103
fatcat:rsl6zqy77refzfzhibmukl2gh4
Protection from herpes simplex virus type 1 lethal and latent infections by secreted recombinant glycoprotein B constitutively expressed in human cells with a BK virus episomal vector
1990
Journal of Virology
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is application/pdf.
The herpes simplex virus type 1 (HSV-1) glycoprotein B (gB-1) gene, deleted of 639 nucleotides that encode the transmembrane anchor sequence and reconstructed with the extramembrane and intracytoplasmic ...
Mice immunized with secreted gB-1 produced HSV-1and HSV-2-neutralizing antibodies and were protected against HSV-1 lethal, latent, and recurrent infections. ...
The deleted gB-1 gene was then reconstructed by self-ligation to put in frame sequences coding for the extramembrane and C-terminal intracytoplasmic domains (Fig. 1 ). ...
doi:10.1128/jvi.64.1.431-436.1990
fatcat:nd7peb2y7rf3vmsyz3avvp6kqu
« Previous
Showing results 1 — 15 out of 1,821 results