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Phantom Restless Legs Syndrome

Alberto Raggi, Raffaele Ferri
2019 European Neurology  
Raggi/Ferri Eur Neurol 2019;81:302-308  ... 
doi:10.1159/000503103 pmid:31536997 fatcat:x5sadlq6vvdhtlsqcrjdqzelvu

Sleep in Children with Neurodevelopmental Disabilities

Marco Angriman, Barbara Caravale, Luana Novelli, Raffaele Ferri, Oliviero Bruni
2015 Neuropediatrics  
[9] [10] [11] In addition, Ferri et al hypothesized a brain stem dysfunction in DS, responsible for the abnormal imbalance between the sympathetic and vagal systems and confirms the presence of central  ... 
doi:10.1055/s-0035-1550151 pmid:25918987 fatcat:a43l6vebcjh7th75uos5d2saem

The Napping Behaviour of Australian University Students

Nicole Lovato, Leon Lack, Helen Wright, Raffaele Ferri
2014 PLoS ONE  
The purpose of this study was to evaluate the self-reported sleep and napping behaviour of Australian university students and the relationship between napping and daytime functioning. A sample of 280 university first-year psychology students (median age = 19.00 years) completed a 6-item napping behaviour questionnaire, a 12-item Daytime Feelings and Functioning Scale, the Pittsburg Sleep Quality Index and the Epworth Sleepiness Scale. Results indicated that 53.6% of students reported napping
more » ... h 34% napping at least 1-2 times per week, and 17% napping three or more occasions per week. Long naps, those over 30 minutes, were taken by 77% of the napping students. Sixty-one percent of students reported they took long naps during the post-lunch dip period, from 2-4pm. Students who nap at least once per week reported significantly more problems organizing their thoughts, gaining motivation, concentrating, and finishing tasks than students who did not nap. Students who napped also felt significantly more sleepy and depressed when compared to students who did not nap. The results also indicated that nap frequency increased with daytime sleepiness. The majority of students (51%) reported sleeping 6-7 hours per night or less. Overall, the results from this study suggest that among this population of Australian first-year university students habitual napping is common and may be used in an attempt to compensate for the detrimental effects of excessive sleepiness.
doi:10.1371/journal.pone.0113666 pmid:25412257 pmcid:PMC4239099 fatcat:njoenczfrzebznq5khvvrn7xny

The Correlation between Sleep and Creativity

Valeria Drago, Debora Aricò, Kenneth Heilman, Paul Foster, John Williamson, Pasquale Montagna, Raffaele Ferri
2010 Nature Precedings  
topographic mapping of the EEG slow-wave component of one A1 subtype is shown, together with the scalp topographic mapping of the EEG high-frequency component of the A3 subtype, obtained as already reported by Ferri  ... 
doi:10.1038/npre.2010.4266.1 fatcat:27rdclhfu5gyvisffdk4eprhie

Maritime Linked Data for Situational Awareness Heterogeneous Sensor Networks

Elena CAMOSSI, Raffaele GRASSO, Gabriele FERRI, Alessandro FAGGIANI, Kevin LePAGE, Sandro CARNIEL
2021 Zenodo  
Maritime heterogeneous sensor networks (HSN), which are widely used in support of marine monitoring, maritime security and safety applications, combine diversified sensing systems and platforms observing the state of environmental features of interest or the status of anthropogenic objects to achieve awareness on the situation. To model the information characteristics of HSN observations for maritime situational awareness (MSA), we developed the MSA-HSN ontology, an integrated semantic model
more » ... maritime linked data, specifically observations suiting the requirements of maritime information fusion systems. MSA-HSN integrates established ontologies and models for sensors, observations, measurements, quantities, and occurrents, tailored to MSA applications and requirements. To support the interoperability with existing maritime data models, MSA-HSN is aligned with the relevant aspects of the EUCISE/e-CISE (Common Information Sharing Environment) data models. As a validation use case, in this paper the MSA-HSN ontology is applied to model the information elements of the maritime surveillance system developed within the Interactive Extreme-Scale Analytics and Forecasting (INFORE) project, where different situational views offered by a variegate suite of sensors and platforms are fused using big data analytics to achieve maritime situational awareness for maritime security. The paper describes the design of the MSA-HSN ontology, illustrating its application through examples taken from the INFORE use case and from relevant datasets developed by recent European projects involving MSA use cases.
doi:10.5281/zenodo.6368994 fatcat:5ixnaljwhjhjpamgr33ihjchvi

Diurnal Emotional States Impact the Sleep Course

Julien Delannoy, Osamu Mandai, Jacques Honoré, Toshinori Kobayashi, Henrique Sequeira, Raffaele Ferri
2015 PLoS ONE  
Diurnal emotional experiences seem to affect several characteristics of sleep architecture. However, this influence remains unclear, especially for positive emotions. In addition, electrodermal activity (EDA), a sympathetic robust indicator of emotional arousal, differs depending on the sleep stage. The present research has a double aim: to identify the specific effects of pre-sleep emotional states on the architecture of the subsequent sleep period; to relate such states to the sympathetic
more » ... vation during the same sleep period. Methods Twelve healthy volunteers (20.1 ± 1.0 yo.) participated in the experiment and each one slept 9 nights at the laboratory, divided into 3 sessions, one per week. Each session was organized over three nights. A reference night, allowing baseline pre-sleep and sleep recordings, preceded an experimental night before which participants watched a negative, neutral, or positive movie. The third and last night was devoted to analyzing the potential recovery or persistence of emotional effects induced before the experimental night. Standard polysomnography and EDA were recorded during all the nights. Fig 2. PANAS PA-NA scores as a function of movies and nights. Percentages of variation relative to the Ref night (Δ Ref ; means and standard errors of means). Ref, Exp and Rec: Reference, Experimental and Recovery nights. Negative, Neutral and Positive: valences of the movies used for emotional induction. Note the valence effect observed for the Exp night and recovering for the Rec night (red and green curves).
doi:10.1371/journal.pone.0142721 pmid:26606526 pmcid:PMC4659651 fatcat:6cs7tm2kevahtesrwm5owef2pu

The Role of NREM Sleep Instability in Child Cognitive Performance

Oliviero Bruni, Mark Kohler, Luana Novelli, Declan Kennedy, Kurt Lushington, James Martin, Raffaele Ferri
2012 Sleep  
Children with higher cognitive efficiency showed an increase of phase A1 in total sleep and in SWS Citation: Bruni O; Kohler M; Novelli L; Kennedy D; Lushington K; Martin J; Ferri R.  ...  Ferri et al., 4 in 15 healthy adults, investigated the impact of sleep microfragmentation on spatial attention, selective attention cognitive flexibility, visuospatial processing, and inhibition/perceptuoattentional  ...  Ferri has consulted for Merck & Co., Sanofi-Aventis, and Sapio Life. The other authors have indicated no financial conflicts of interest.  ... 
doi:10.5665/sleep.1824 pmid:22547891 pmcid:PMC3321424 fatcat:7qrae4a2hfetre25lhdrqkoyom

Stability of Auditory Discrimination and Novelty Processing in Physiological Aging

Alberto Raggi, Domenica Tasca, Francesco Rundo, Raffaele Ferri
2013 Behavioural Neurology  
Complex higher-order cognitive functions and their possible changes with aging are mandatory objectives of cognitive neuroscience. Event-related potentials (ERPs) allow investigators to probe the earliest stages of information processing. N100, Mismatch negativity (MMN) and P3a are auditory ERP components that reflect automatic sensory discrimination. The aim of the present study was to determine if N100, MMN and P3a parameters are stable in healthy aged subjects, compared to those of normal
more » ... ng adults. Normal young adults and older participants were assessed using standardized cognitive functional instruments and their ERPs were obtained with an auditory stimulation at two different interstimulus intervals, during a passive paradigm. All individuals were within the normal range on cognitive tests. No significant differences were found for any ERP parameters obtained from the two age groups. This study shows that aging is characterized by a stability of the auditory discrimination and novelty processing. This is important for the arrangement of normative for the detection of subtle preclinical changes due to abnormal brain aging.
doi:10.1155/2013/462462 pmid:23242351 pmcid:PMC5215744 fatcat:2kcccjhtsvcedapiyelz2e6v6m

Electroencephalographic Rhythms in Alzheimer's Disease

Roberta Lizio, Fabrizio Vecchio, Giovanni B. Frisoni, Raffaele Ferri, Guido Rodriguez, Claudio Babiloni
2011 International Journal of Alzheimer's Disease  
Physiological brain aging is characterized by synapses loss and neurodegeneration that slowly lead to an age-related decline of cognition. Neural/synaptic redundancy and plastic remodelling of brain networking, also due to mental and physical training, promotes maintenance of brain activity in healthy elderly subjects for everyday life and good social behaviour and intellectual capabilities. However, age is the major risk factor for most common neurodegenerative disorders that impact on
more » ... n, like Alzheimer's disease (AD). Brain electromagnetic activity is a feature of neuronal network function in various brain regions. Modern neurophysiological techniques, such as electroencephalography (EEG) and event-related potentials (ERPs), are useful tools in the investigation of brain cognitive function in normal and pathological aging with an excellent time resolution. These techniques can index normal and abnormal brain aging analysis of corticocortical connectivity and neuronal synchronization of rhythmic oscillations at various frequencies. The present review suggests that discrimination between physiological and pathological brain aging clearly emerges at the group level, with suggested applications also at the level of single individual. The possibility of combining the use of EEG together with biological/neuropsychological markers and structural/functional imaging is promising for a low-cost, non-invasive, and widely available assessment of groups of individuals at-risk.
doi:10.4061/2011/927573 pmid:21629714 pmcid:PMC3100729 fatcat:72hx7mkpizchvjtyomoaa6tafa

Sleep Cyclic Alternating Pattern in Otherwise Healthy Overweight School-Age Children

Rodrigo Chamorro, Raffaele Ferri, Cecilia Algarín, Marcelo Garrido, Betsy Lozoff, Patricio Peirano
2014 Sleep  
Ferri has consulted for Merck & Co., Sapio Life, and EB Neuro. Dr. Lozoff has participated in speaking engagements supported by Vifor Pharma and Lee's Pharm.  ... 
doi:10.5665/sleep.3496 pmid:24587578 pmcid:PMC3920321 fatcat:zonzynzmwfekdpmbgdcve6jhmi

Severe restless legs syndrome in a family with Alport syndrome

Davide Sparasci, Andrea Rossinelli, Raffaele Ferri, Pietro Cippà, Andrea Rinaldi, Mauro Manconi
2021 BMC Nephrology  
Background Restless legs syndrome (RLS) is a common sleep-related movement disorder characterized by an urge to move the legs during inactivity, especially at evening-night. RLS is highly prevalent in patients with kidney failure and have an impact on quality of life, mood, sleep quality and overall on compliance to the dialysis. Alport syndrome (AS) is a rare inherited disease, predominantly X-linked, secondary to mutations in genes encoding α3, α4 or α5 chains of type IV collagen, and
more » ... rized by hematuria, chronic kidney disease, neurosensory deafness, and lenticonus. Case presentation Here we describe a family with a combination of X-linked AS and severe RLS accompanied by periodic limb movements during sleep (PLMS). In the first patient we identified, RLS was complicated by a paradoxical response to dopamine agonists named "augmentation", leading to sleep disruption, hallucinations and five peritoneal perforations during the peritoneal dialysis due to the difficulty to rest still. Therapeutic adjustments and renal transplantation improved RLS and PLMS. In two brothers, severe RLS prevented a compliance with hemodialysis. Female family members carrying the mutation were also affected by RLS, while those without the mutations were RLS-free. Conclusions RLS has not been reported earlier in association with AS, but the peculiar combinations observed in this family will stimulate further clinical studies and motivate nephrologists to seek for RLS symptoms and sleep disturbances in AS patients.
doi:10.1186/s12882-021-02455-2 pmid:34225668 pmcid:PMC8256610 fatcat:22v3im44b5awpjed3prhhe3mmm

Ropinirole in restless legs syndrome and periodic limb movement disorder

Daniel Erichsen, Raffaelle Ferri, David Gozal
2010 Therapeutics and Clinical Risk Management  
Restless legs syndrome and periodic limb movement disorder of sleep are now recognized as prevalent, distinct, yet overlapping disorders affecting all age groups. Although delineation of the mechanisms underlying these disorders continues to be the focus of very intense research efforts, it has become apparent that there is a prominent role for dopaminergic agents in the clinical management of these patients. Among the various dopaminergic drugs, ropinirole has undergone relatively intense and
more » ... ritical scrutiny, and appears to provide a safe and efficacious treatment option for patients with these two conditions. The more recent development of a controlled formulation for this drug is likely to yield additional benefits such as improved adherence and reduced fluctuations in daytime and nighttime symptoms. However, there is not enough evidence at this time to support such assumption.
pmid:20421915 pmcid:PMC2857615 fatcat:ikuoj5ey4jdxrcgxhdn3alkxty

Nervous system involvement in Degos disease

Carmelo Amato, Raffaele Ferri, Maurizio Elia, Filomena Cosentino, Carmelo Schepis, Maddalena Siragusa, Massimo Moschini
2005 American Journal of Neuroradiology  
Degos disease, or malignant atrophic papulosis, is a rare obstructive vasculopathy of unknown origin, characterized by distinctive skin lesions, visceral involvement, and an unfavorable outcome. The gastrointestinal tract and the central nervous system are most frequently affected, but cases limited to benign skin lesions have also been described. Neuroradiologic reports of this condition are exceptionally rare. We report the case of a 29-year-old woman with central and peripheral nervous
more » ... involvement who presented with progressive clinical deterioration and a meningovascular pattern at cerebral MR imaging; other organs were spared in this patient.
pmid:15760880 pmcid:PMC7976473 fatcat:2dck2o5pcbdffpk7qz4q45opqy
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