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RCSB Protein Data Bank: powerful new tools for exploring 3D structures of biological macromolecules for basic and applied research and education in fundamental biology, biomedicine, biotechnology, bioengineering and energy sciences
2020
Nucleic Acids Research
Preserved Fulltext
PDB data consumers accessing our web portals include researchers, educators and students studying fundamental biology, biomedicine, biotechnology, bioengineering and energy sciences. ...
The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB), the US data center for the global PDB archive and a founding member of the Worldwide Protein Data Bank partnership ...
ACKNOWLEDGEMENTS RCSB PDB is a member of the Worldwide Protein Data Bank (wwPDB.org). ...
doi:10.1093/nar/gkaa1038
pmid:33211854
pmcid:PMC7779003
fatcat:dkqo54quqjgovp7y4v67b635zu
Multimodal Pre-Training Model for Sequence-based Prediction of Protein-Protein Interaction
[article]
2021
arXiv
pre-print
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Protein-protein interactions (PPIs) are essentials for many biological processes where two or more proteins physically bind together to achieve their functions. ...
However, neither sequences nor contact maps can fully characterize structures and functions of the proteins, which are closely related to the PPI problem. ...
Rcsb protein data bank: powerful new
tools for exploring 3d structures of biological macromolecules for basic and applied research and education in ...
arXiv:2112.04814v1
fatcat:areao63ioncdrf46jr5ty6kdb4
Invited Speaker Abstracts
2019
Turk biyokimya dergisi = Turkish journal of biochemistry
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Protein Data Base (RCSB PDB) is one of the most important databases for achieving the 3D version of the cancer target which contain more than 1 TB of Structure Data for Proteins, DNA, and RNA. ...
Karaca will briefly introduce the basic Structural Biology techniques and the data types acquired with them. ...
According to the World Health Organization data, about 2 million new lung cancer cases are diagnosed each year [1] . In our country, the incidence of lung cancer is 29,314. ...
doi:10.1515/tjb-2019-44s205
fatcat:ylzu5whwindujpg47qcrcgfr4a
Mitochondrial energy dysfunction induces remodeling of the cardiac mitochondrial protein acylome
[article]
2021
bioRxiv
pre-print
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The specific pathway(s) engaged by mitochondria in response to defects in mitochondrial energy production in vivo and in high-energy tissues like the heart are not fully understood. ...
Mass spectrometry-based proteomics further revealed that energy dysfunction-induced remodeling of the acetylome and malonylome preferentially impacts mitochondrial proteins. ...
., and Zhuravleva, M. (2021) RCSB Protein Data Bank: powerful new tools for exploring 3D structures of biological macromolecules for basic and applied research and education in fundamental biology, biomedicine ...
doi:10.1101/2021.01.31.429057
fatcat:tnkgowmf7jbobhywla5hi7uinm
Cytomegalovirus immediate-early 1 proteins form a structurally distinct protein class with adaptations determining cross-species barriers
2021
PLoS Pathogens
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Furthermore, our data show that the IE1 fold has been adapted to maximize the efficacy of PML targeting in a species-specific manner and support the concept that the PML-NBs-based intrinsic defense constitutes ...
We conclude that cytomegaloviruses have evolved a distinct protein tertiary structure of IE1 to effectively bind and inactivate an important cellular restriction factor. ...
Acknowledgments We would like to thank Manfred Weiss and Uwe Müller and their team for help with data collection at beamline 14.2 at BESSY synchrotron and Max Kraner from the Biochemistry Division of the ...
doi:10.1371/journal.ppat.1009863
pmid:34370791
pmcid:PMC8376021
fatcat:ccwb6a4vafborcbnhvoxrxcxyq
Cytomegalovirus immediate-early 1 proteins form a structurally distinct protein class with adaptations determining cross-species barriers
2021
Preserved Fulltext
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Furthermore, our data show that the IE1 fold has been adapted to maximize the efficacy of PML targeting in a species-specific manner and support the concept that the PML-NBs-based intrinsic defense constitutes ...
We conclude that cytomegaloviruses have evolved a distinct protein tertiary structure of IE1 to effectively bind and inactivate an important cellular restriction factor. ...
Acknowledgments We would like to thank Manfred Weiss and Uwe Müller and their team for help with data collection at beamline 14.2 at BESSY synchrotron and Max Kraner from the Biochemistry Division of the ...
doi:10.3204/pubdb-2021-03854
fatcat:sc2ajloli5fsxkfc4v5virbaom
COLECISTITE ASSOCIADA A ÍLEO BILIAR: UM RELATO DE CASO
[chapter]
2021
AMPLAMENTE: DESAFIOS EM SAÚDE
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It was concluded that there was a considerable reduction in fat mass and an increase in lean mass. ...
The body composition was described by the 2component model, and the anthropometric measurements through the references of the International Society for the Advancement of Cineanthropometry (ISAK). ...
RCSB Protein Data Bank: Powerful new tools for exploring 3D
structures of biological macromolecules for basic and applied research and education in
fundamental biology, biomedicine, biotechnology, bioengineering ...
doi:10.47538/ac-2021.02-04
fatcat:zrma4o77rrcshffmq2k7dbrwxe