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RCSB Protein Data Bank: biological macromolecular structures enabling research and education in fundamental biology, biomedicine, biotechnology and energy

Stephen K Burley, Helen M Berman, Charmi Bhikadiya, Chunxiao Bi, Li Chen, Luigi Di Costanzo, Cole Christie, Ken Dalenberg, Jose M Duarte, Shuchismita Dutta, Zukang Feng, Sutapa Ghosh (+28 others)
2018 Nucleic Acids Research  
PDB Data Consumers include researchers, educators and students studying Fundamental Biology, Biomedicine, Biotechnology and Energy.  ...  The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB, rcsb.org), the US data center for the global PDB archive, serves thousands of Data Depositors in the Americas and Oceania  ...  We gratefully acknowledge contributions from past members of the RCSB PDB team and our Worldwide Protein Data Bank partners.  ... 
doi:10.1093/nar/gky1004 pmid:30357411 pmcid:PMC6324064 fatcat:clctmqo6ujaifm7s27vk3s2h7i

RCSB Protein Data Bank: Sustaining a living digital data resource that enables breakthroughs in scientific research and biomedical education

Stephen K. Burley, Helen M. Berman, Cole Christie, Jose M. Duarte, Zukang Feng, John Westbrook, Jasmine Young, Christine Zardecki
2017 Protein Science  
In addition, RCSB PDB served >1 million RCSB.org users worldwide with PDB data integrated with~40 external data resources providing rich structural views of fundamental biology, biomedicine, and energy  ...  The Protein Data Bank (PDB) is one of two archival resources for experimental data central to biomedical research and education worldwide (the other key Primary Data Archive in biology being the International  ...  PDB in three subject areas Fundamental Biology, Biomedicine, and Energy Research.  ... 
doi:10.1002/pro.3331 pmid:29067736 pmcid:PMC5734314 fatcat:7jdrdkkw6ffffeu2xpsqp3le4i

RCSB Protein Data Bank: powerful new tools for exploring 3D structures of biological macromolecules for basic and applied research and education in fundamental biology, biomedicine, biotechnology, bioengineering and energy sciences

Stephen K Burley, Charmi Bhikadiya, Chunxiao Bi, Sebastian Bittrich, Li Chen, Gregg V Crichlow, Cole H Christie, Kenneth Dalenberg, Luigi Di Costanzo, Jose M Duarte, Shuchismita Dutta, Zukang Feng (+26 others)
2020 Nucleic Acids Research  
PDB data consumers accessing our web portals include researchers, educators and students studying fundamental biology, biomedicine, biotechnology, bioengineering and energy sciences.  ...  The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB), the US data center for the global PDB archive and a founding member of the Worldwide Protein Data Bank partnership  ...  ACKNOWLEDGEMENTS RCSB PDB is a member of the Worldwide Protein Data Bank (wwPDB.org).  ... 
doi:10.1093/nar/gkaa1038 pmid:33211854 pmcid:PMC7779003 fatcat:dkqo54quqjgovp7y4v67b635zu

Impact of structural biologists and the Protein Data Bank on small-molecule drug discovery and development

Stephen K. Burley
2021 Journal of Biological Chemistry  
Bank in Europe, Protein Data Bank Japan, Biological Magnetic Resonance Bank, and Electron Microscopy Data Bank).  ...  Finally, the author gratefully acknowledges contributions to the success of the PDB archive made by all members of RCSB PDB (past and present) and our Worldwide Protein Data Bank partners (Protein Data  ...  It is central to research and education in fundamental biology, biomedicine, biotechnology/ bioengineering, and energy sciences worldwide (Fig. 1 ; (4)).  ... 
doi:10.1016/j.jbc.2021.100559 pmid:33744282 fatcat:7aumkkjssrbn3mmx5k4jwvenoa

Worldwide Protein Data Bank (wwPDB): A virtual treasure for research in biotechnology

Payam Behzadi, Márió Gajdács
2021
The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RSCB PDB) provides a wide range of digital data regarding biology and biomedicine.  ...  The Worldwide Protein Data Bank (wwPDB) represents a brilliant collection of 3D structure data associated with important and vital biomolecules including nucleic acids (RNAs and DNAs) and proteins.  ...  It is estimated that more than 660 k of RCSB PDB users are students, researchers and educators (from different fields involving bioengineering, biomedicine, biotechnology and fundamental biology) who utilize  ... 
doi:10.1556/1886.2021.00020 pmid:34908533 pmcid:PMC8830413 fatcat:ty66cfarond4dairw3bfhuuvom

A Survey of Scholarly Literature Describing the Field of Bioinformatics Education and Bioinformatics Educational Research

Alejandra J. Magana, Manaz Taleyarkhan, Daniela Rivera Alvarado, Michael Kane, John Springer, Kari Clase, Mary Lee Ledbetter
2014 CBE - Life Sciences Education  
The recent surge of genomics, proteomics, and structural biology in the potential advancement of research and development in complex biomedical systems has created a need for an educated workforce in bioinformatics  ...  analyzing, interpreting, and integrating data to solve biological problems.  ...  The biology and biotechnology category (Figure 2 , Bio. and Biotech.) included 12 papers (11%) related to medical and biological engineering, biotechnology, science, and systems biology.  ... 
doi:10.1187/cbe.13-10-0193 pmid:25452484 pmcid:PMC4255348 fatcat:2uilrbzzzja4nmsetfzw6mbkau

Artificial intelligence to deep learning: machine intelligence approach for drug discovery

Rohan Gupta, Devesh Srivastava, Mehar Sahu, Swati Tiwari, Rashmi K Ambasta, Pravir Kumar
2021 Molecular diversity  
structure-activity relationship to drug repositioning, protein misfolding to protein-protein interactions, and molecular pathway identification to polypharmacology.  ...  Further, complex and big data from genomics, proteomics, microarray data, and clinical trials also impose an obstacle in the drug discovery pipeline.  ...  RKA and PK given their critical comments and structured this paper. Art work is done by RG, RAK, and PK. Paper is written by PK.  ... 
doi:10.1007/s11030-021-10217-3 pmid:33844136 pmcid:PMC8040371 fatcat:yltthjorrvfrjgyrnszpxgpb2q

Report of the Executive Committee for 2020

A. T. Ashcroft
2022 Acta Crystallographica Section A: Foundations and Advances  
matter, biomedicine, energy and materials science.  ...  of the course Selected Protein Data Bank (PDB) Small-Angle Scattering Validation Physicochemical Methods in Biology.  ... 
doi:10.1107/s2053273321012067 pmid:34967332 fatcat:vgryy42a7rcidannzv5l5ptk7y

NONU-1 encodes a conserved endonuclease required for mRNA translation surveillance [article]

Marissa L Glover, A Maxwell Burroughs, Thea A Egelhofer, Makena N Pule, L Aravind, Joshua A Arribere
2019 bioRxiv   pre-print
We extend our results in C. elegans to homologous factors in S. cerevisiae, showing conservation of function of the NONU-1 protein across billions of years of evolution.  ...  architecture and catalytic residues of NONU-1 are conserved throughout metazoans and eukaryotes, respectively.  ...  RCSB Protein Data Bank: biological macromolecular structures enabling research and education in fundamental biology, biomedicine, biotechnology and energy. Nucleic Acids Res 47: D464-D474.  ... 
doi:10.1101/674358 fatcat:fvr752p4zjhf5pq4pv3kmsxs5u

Chamonix, France BIOTECHNO 2014 Editors BIOTECHNO 2014 Committee BIOTECHNO Advisory Chairs BIOTECHNO 2014 Technical Program Committee

Hesham Ali, Stephen Anthony, Hesham Ali, Stephen Anthony, Hesham Ali, Yili Chen, Tom Bersano, Clara Pizzuti, Icar-Cnr -Rende, John Spounge, Basim Alhadidi, Albalqa (+54 others)
2014 Daisuke Kihara   unpublished
The focus is driven by fundamentals in approaching and applying biotechnologies in terms of engineering methods, special electronics, and special materials and systems.  ...  Biotechnology is defined as the industrial use of living organisms or biological techniques developed through basic research.  ...  Research supported in part by NSF grants CCF-0926190 and CCF-1018459, and by AFOSR grant FA0550-09-1-0481.  ... 
fatcat:mrib6ha45ra7vlyxc57i5shr2y