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Fully-automated volumetric MRI with normative ranges: translation to clinical practice

J B Brewer
<span title="">2009</span> <i title="Hindawi Limited"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/lplhrqfxibdapixms7fsblzldu" style="color: black;">Behavioural Neurology</a> </i> &nbsp;
Neurodegenerative disorders, such as Alzheimer's disease (AD), are associated with characteristic patterns of neuropathological spread in the brain.  ...  A wealth of data has demonstrated the value of quantitative measurements of regional atrophy in AD, suggesting that volumetric MRI (vMRI) may be a useful clinical tool. vMRI provides biological evidence  ...  Introduction Noninvasive measurement of disease-related brain atrophy is potentially a powerful tool for early detection and monitoring of neurodegenerative disease, such as Alzheimer's disease (AD).  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3233/ben-2009-0226">doi:10.3233/ben-2009-0226</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/19847042">pmid:19847042</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC5444284/">pmcid:PMC5444284</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/axk6pulfgjhdfk6cwtbvgua6py">fatcat:axk6pulfgjhdfk6cwtbvgua6py</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200210171352/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC5444284&amp;blobtype=pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/ae/8d/ae8ddb6f977fc193deb241f789d29c748d12c629.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3233/ben-2009-0226"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444284" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Studying Alzheimer disease, Parkinson disease, and amyotrophic lateral sclerosis with 7-T magnetic resonance

Emrah Düzel, Mauro Costagli, Graziella Donatelli, Oliver Speck, Mirco Cosottini
<span title="2021-08-26">2021</span> <i title="SpringerOpen"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/cfc7hazrmfhnjazjfkwn6bq5oa" style="color: black;">European Radiology Experimental</a> </i> &nbsp;
This article reviews the 7 T MR literature reporting the recent studies on the most widespread neurodegenerative diseases: Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis.  ...  Ultra-high-field (UHF) magnetic resonance (MR) scanners, that is, equipment operating at static magnetic field of 7 tesla (7 T) and above, enable the acquisition of data with greatly improved signal-to-noise  ...  In addition, QSM can help imaging venous vessels and their role in clearance of interstitial fluid and toxic waste and thus provide complementary information to TOF imaging of the arterial system.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/s41747-021-00221-5">doi:10.1186/s41747-021-00221-5</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/34435242">pmid:34435242</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC8387546/">pmcid:PMC8387546</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/w2ikouzghbbjflbhkplqgkrqea">fatcat:w2ikouzghbbjflbhkplqgkrqea</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20210915132118/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC8387546&amp;blobtype=pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/f5/b2/f5b21d5c67df0debe668efe64b855e75e47e1cd1.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/s41747-021-00221-5"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> springer.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387546" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Quantitative Magnetization Transfer of White Matter Tracts Correlates with Diffusion Tensor Imaging Indices in Predicting the Conversion from Mild Cognitive Impairment to Alzheimer's Disease

Elena Makovac, Laura Serra, Carlotta Di Domenico, Camillo Marra, Carlo Caltagirone, Mara Cercignani, Marco Bozzali
<span title="2018-04-24">2018</span> <i title="IOS Press"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/uux5o5kf5zaednhl4637xcmbte" style="color: black;">Journal of Alzheimer&#39;s Disease</a> </i> &nbsp;
Both diffusion tensor imaging (DTI) and quantitative magnetization transfer (qMT) parameters have been considered for a comprehensive pathophysiological characterization of the WM damage.  ...  The detection of subtle changes in brain structure associated with disease progression and the development of tools to identify patients at high risk for dementia in a short time is crucial.  ...  All subjects gave written informed consent before taking part in the study.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3233/jad-170995">doi:10.3233/jad-170995</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/29689722">pmid:29689722</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/kmbkgkj245dohliqq7ygnnz7e4">fatcat:kmbkgkj245dohliqq7ygnnz7e4</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20190427232436/http://sro.sussex.ac.uk/id/eprint/75730/1/Quantitative%20Magnetisation%20Transfer%20of%20White%20Matter%20Tracts%20-%20Bozzali%20M.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/d9/11/d911b0cf11ca50a6f93e3f516ef1b36a733d6df2.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3233/jad-170995"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a>

In vivo exploration of synaptic projections in frontotemporal dementia

Eric Salmon, Mohamed Ali Bahri, Alain Plenevaux, Guillaume Becker, Alain Seret, Emma Delhaye, Christian Degueldre, Evelyne Balteau, Christian Lemaire, André Luxen, Christine Bastin
<span title="2021-08-09">2021</span> <i title="Springer Science and Business Media LLC"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/tnqhc2x2aneavcd3gx5h7mswhm" style="color: black;">Scientific Reports</a> </i> &nbsp;
Twelve patients with probable bvFTD were compared to 12 control participants and 12 patients with Alzheimer's disease (AD). Loss of synaptic projections was assessed with [18F]UCBH-PET.  ...  AbstractThe purpose of this exploratory research is to provide data on synaptopathy in the behavioral variant of frontotemporal dementia (bvFTD).  ...  The modulated normalized grey matter images across the study sample were used to create a grey matter mask for the statistical analyses.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1038/s41598-021-95499-1">doi:10.1038/s41598-021-95499-1</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/34373529">pmid:34373529</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC8352914/">pmcid:PMC8352914</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/lpuuk2gqpfdnfakaeohkzpgzni">fatcat:lpuuk2gqpfdnfakaeohkzpgzni</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20211109091721/https://orbi.uliege.be/bitstream/2268/264902/1/Scientific%20Report%202021%20Salmon.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/65/ad/65ad45f88c431117aa3acba2e9f13f4d1072eb5d.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1038/s41598-021-95499-1"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8352914" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Aging of cerebral white matter: a review of MRI findings

Faith M. Gunning-Dixon, Adam M. Brickman, Janice C. Cheng, George S. Alexopoulos
<span title="">2009</span> <i title="Wiley"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/lflfqvy7zja77bmkgvvqpt7jou" style="color: black;">International Journal of Geriatric Psychiatry</a> </i> &nbsp;
Structural magnetic resonance imaging (MRI) can be used to identify and quantify non-disease-related aging of the cerebral white matter.  ...  Magnetic resonance imaging (MRI) makes in vivo characterization of brain alterations occurring with advancing age possible.  ...  Macromolecular White Matter Changes Magnetization transfer ratio (MTR) imaging provides information about the macromolecular structure of cerebral white matter based on the interaction of the normally  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1002/gps.2087">doi:10.1002/gps.2087</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/18637641">pmid:18637641</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC2631089/">pmcid:PMC2631089</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/5plgws7durgk7anjtxrbpuyuuq">fatcat:5plgws7durgk7anjtxrbpuyuuq</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20191030174903/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC2631089&amp;blobtype=pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/aa/50/aa50e1fcae73e6c689ec83297a8ffa4bf3e29f19.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1002/gps.2087"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> wiley.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631089" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Tissue magnetic susceptibility mapping as a marker of tau pathology in Alzheimer's disease

J. O'Callaghan, H. Holmes, N. Powell, J.A. Wells, O. Ismail, I.F. Harrison, B. Siow, R. Johnson, Z. Ahmed, A. Fisher, S. Meftah, M.J. O'Neill (+4 others)
<span title="">2017</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/sa477uo7lveh7hchpikpixop5u" style="color: black;">NeuroImage</a> </i> &nbsp;
A B S T R A C T Alzheimer's disease is connected to a number of other neurodegenerative conditions, known collectively as 'tauopathies', by the presence of aggregated tau protein in the brain.  ...  Neuroinflammation and oxidative stress in AD are associated with tau pathology and both the breakdown of axonal sheaths in white matter tracts and excess iron accumulation grey matter brain regions.  ...  Introduction Alzheimer's disease (AD) is defined by the presence of amyloid-β plaque and neurofibrillary tangle (NFT) tau pathology found primarily in grey matter regions of the brain.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.neuroimage.2017.08.003">doi:10.1016/j.neuroimage.2017.08.003</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/28797738">pmid:28797738</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC5678288/">pmcid:PMC5678288</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/gowljys7mvhv3asqcwh5cgzupq">fatcat:gowljys7mvhv3asqcwh5cgzupq</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20180723052126/http://discovery.ucl.ac.uk/1570376/1/1-s2.0-S105381191730650X-main.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/7e/39/7e39ecc9a4e2beed96ad8e4f4473c44253856e72.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.neuroimage.2017.08.003"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> elsevier.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678288" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Currently Available Neuroimaging Approaches in Alzheimer Disease (AD) Early Diagnosis [chapter]

Laura Ortiz-Teran, Juan MR, Maria de las Nieves Cabrera Martin, Tomas Ortiz
<span title="2011-09-06">2011</span> <i title="InTech"> The Clinical Spectrum of Alzheimer&#39;s Disease -The Charge Toward Comprehensive Diagnostic and Therapeutic Strategies </i> &nbsp;
Neuroimaging technique Finding CT Tissue atrophy. MRI Tissue atrophy. It is more specific about grey matter. fMRI Changes in blood oxygenation level (BOLD signal) representing synaptic activity.  ...  These changes may help to differentiate between AD, MCI and normality as well as providing some clues about differences in information processing in these same conditions Different studies carried out  ...  Patients with AD show decreased fiber density in temporal white matter, probably related to the medial temporal grey matter atrophy, as well as in the splenium of the corpus callosum.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.5772/17012">doi:10.5772/17012</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/7pxfsz3bgfdbnbaxakb33j3zci">fatcat:7pxfsz3bgfdbnbaxakb33j3zci</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20170923234533/https://cdn.intechopen.com/pdfs-wm/19242.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/a8/3e/a83e69aba0ad3837094771586058960dcd9ab9e3.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.5772/17012"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a>

Quantitative Relaxometry of the Brain

Sean C.L. Deoni
<span title="">2010</span> <i title="Ovid Technologies (Wolters Kluwer Health)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/x533syjtsnflheejifpfdaeqka" style="color: black;">Topics in Magnetic Resonance Imaging (TMRI)</a> </i> &nbsp;
referred to as quantitative relaxometry, can be informative of disease-related tissue change, developmental plasticity, and other biological processes.  ...  The exquisite soft tissue contrast provided by magnetic resonance imaging arises principally from differences in the intrinsic relaxation properties, T 1 and T 2 .  ...  compared to grey matter (2) .  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1097/rmr.0b013e31821e56d8">doi:10.1097/rmr.0b013e31821e56d8</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/21613875">pmid:21613875</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3613135/">pmcid:PMC3613135</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/dc4owtdwmnfmbgect3kiackefi">fatcat:dc4owtdwmnfmbgect3kiackefi</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200430043759/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC3613135&amp;blobtype=pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/b1/b5/b1b54c400d9f7bcd4aa8d06f9357ad1d2f66dfa4.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1097/rmr.0b013e31821e56d8"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613135" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

A critical discussion of the role of neuroimaging in mild cognitive impairment

Henrike Wolf, Vesna Jelic, Hermann-Josef Gertz, Agneta Nordberg, Per Julin, Lars-Olof Wahlund
<span title="">2003</span> <i title="Munksgaard"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/jk2yx3b7wja2nk5lrhtojctqae" style="color: black;">Acta Neurologica Scandinavica, Supplementum</a> </i> &nbsp;
Particular attention is drawn to the possible value of neuroimaging modalities in the prediction and early diagnosis of Alzheimer's disease (AD).  ...  In quantitative electroencephalogram (QEEG), low beta, high theta, low alpha and slowed mean frequency were associated with development of dementia.  ...  Despite occasional reports of reduced grey matter or global brain volume (34, 48) , the magnitude of these studies imply that global brain volume, white or grey matter atrophy is not usually pronounced  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/12603252">pmid:12603252</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/6djt5bkwwne4lixvxduwdk53n4">fatcat:6djt5bkwwne4lixvxduwdk53n4</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20170811195553/http://www.henrikewolf.de/mediapool/29/295137/data/Wolf_Acta_corr.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/59/95/59957e650a13f58fd290268880e89478f1d0c708.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a>

Measurement of atrophy in multiple sclerosis: pathological basis, methodological aspects and clinical relevance

D. H. Miller
<span title="2002-08-01">2002</span> <i title="Oxford University Press (OUP)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/3yly6om4ynhcta4fdjenhrdk5y" style="color: black;">Brain</a> </i> &nbsp;
aspartate; NAWM = normal appearing white matter; SPM = statistical parametric mapping; WBR = whole brain ratio ã  ...  Abbreviations: BFV = brain fraction volume; BICCR = brain intracranial capacity ratio; BPF = brain parenchymal fraction; CIS = clinically isolated syndromes; COV = coef®cient of variance; EDSS = expanded  ...  Change in cerebral volume over 1 year correlated only weakly with change in T 1 and T 2 brain load, suggesting that the measurement of atrophy provides complementary information.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1093/brain/awf177">doi:10.1093/brain/awf177</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/12135961">pmid:12135961</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/zxyfwfxaizhira3tzf25x4ef6y">fatcat:zxyfwfxaizhira3tzf25x4ef6y</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20150906112937/http://brain.oxfordjournals.org:80/content/brain/125/8/1676.full.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/91/e3/91e3e9960531d36097ad4d87f904275328619b7e.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1093/brain/awf177"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> oup.com </button> </a>

Electroencephalography-driven approach to prodromal Alzheimer's disease diagnosis: from biomarker integration to network-level comprehension

Moretti DV
<span title="">2016</span> <i title="Dove Medical Press"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/6uiyl45r3bdwzkfm3eyvychzhq" style="color: black;">Clinical Interventions in Aging</a> </i> &nbsp;
Alzheimer's disease (AD).  ...  Davide Vito Moretti Rehabilitation in Alzheimer's Disease Operative Unit, IRCCS San Giovanni di Dio, Fatebenefratelli, Brescia, Italy Abstract: Decay of the temporoparietal cortex is associated with prodromal  ...  The topography of grey matter involvement in early and late onset Alzheimer’s disease. Frisoni GB, Ganzola R, Canu E, et al.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener" href="https://doaj.org/article/fa78da26fabd4897b1c6e9c97773b312">doaj:fa78da26fabd4897b1c6e9c97773b312</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/nouewespbbazrkbxlanbx4bau4">fatcat:nouewespbbazrkbxlanbx4bau4</a> </span>
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The causal structure of age-dependent limbic decline: fornix white matter glia damage causes hippocampal grey matter damage, not vice versa [article]

Claudia Metzler-Baddeley, Jilu P. Mole, Rebecca Sims, Fabrizio Fasano, John Evans, Derek K. Jones, John P. Aggleton, Roland J. Baddeley
<span title="2018-10-11">2018</span> <i title="Cold Spring Harbor Laboratory"> bioRxiv </i> &nbsp; <span class="release-stage" >pre-print</span>
We compared these models with linear mediation analysis and quantitative multi-modal MRI indices (from diffusion, quantitative magnetization transfer and relaxometry imaging) of tissue properties in two  ...  AbstractAging leads to gray and white matter decline but their causation remains unclear. We explored two broad classes of models of age and dementia risk related brain changes.  ...  We also would like to thank Rhodri Thomas for his assistance with the APOE genotyping of the saliva samples. The authors declare no competing financial or non-financial interests.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1101/440917">doi:10.1101/440917</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/rmqtdg2vajgdtjcqxg4p7xc44e">fatcat:rmqtdg2vajgdtjcqxg4p7xc44e</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200711030155/https://www.biorxiv.org/content/biorxiv/early/2018/10/11/440917.full.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/50/06/5006e51b557e0753868c247b8b5880fd98ba4999.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1101/440917"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> biorxiv.org </button> </a>

Early role of vascular dysregulation on late-onset Alzheimer's disease based on multifactorial data-driven analysis

Y. Iturria-Medina, R. C. Sotero, P. J. Toussaint, J. M. Mateos-Pérez, A. C. Evans, Michael W. Weiner, Paul Aisen, Ronald Petersen, Clifford R. Jack, William Jagust, John Q. Trojanowki, Arthur W. Toga (+303 others)
<span title="2016-06-21">2016</span> <i title="Springer Nature"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/a4wan6l5o5dfzn767kyz7jqevi" style="color: black;">Nature Communications</a> </i> &nbsp;
in relation to LOAD progression.  ...  We analyse over 7,700 brain images and tens of plasma and cerebrospinal fluid biomarkers from the Alzheimer's Disease Neuroimaging Initiative (ADNI).  ...  Acknowledgements We are grateful to Mélissa Savard and Joshua Morse for their helpful suggestions and comments on the manuscript. This study was partially supported by Brain Canada  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1038/ncomms11934">doi:10.1038/ncomms11934</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/27327500">pmid:27327500</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC4919512/">pmcid:PMC4919512</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/ozbuzdl435buja3hied35gj5sm">fatcat:ozbuzdl435buja3hied35gj5sm</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20190228143857/http://pdfs.semanticscholar.org/93b0/ce610dee365334a4aa7a3cc59b4b8599aa0c.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/93/b0/93b0ce610dee365334a4aa7a3cc59b4b8599aa0c.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1038/ncomms11934"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> nature.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919512" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Towards multimodal atlases of the human brain

Arthur W. Toga, Paul M. Thompson, Susumu Mori, Katrin Amunts, Karl Zilles
<span title="">2006</span> <i title="Springer Nature"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/pt4z3gexdvdshjlzwp4gogrnji" style="color: black;">Nature Reviews Neuroscience</a> </i> &nbsp;
These integrative approaches have provided significant impetus for the human brain mapping initiatives, and have important applications in health and disease.  ...  Cartographic approaches have been used for centuries to identify and target specific regions in the brain and to establish spatial relationships between a coordinate and a structure.  ...  We thank the many collaborators and doctoral students in our laboratories. Special thanks to P. Roland from the Karolinska Institute  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1038/nrn2012">doi:10.1038/nrn2012</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/17115077">pmid:17115077</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3113553/">pmcid:PMC3113553</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/vb3kvw2wrjbahd67546jgvxtky">fatcat:vb3kvw2wrjbahd67546jgvxtky</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200206042833/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC3113553&amp;blobtype=pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/05/bf/05bfe12af0bc55aee0676f686559fdcdcaa0e4a0.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1038/nrn2012"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> nature.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113553" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Advances in Multimodal Data Fusion in Neuroimaging: Overview, Challenges, and Novel Orientation

Yu-Dong Zhang, Zhengchao Dong, Shui-Hua Wang, Xiang Yu, Xujing Yao, Qinghua Zhou, Hua Hu, Min Li, Carmen Jiménez-Mesa, Javier Ramirez, Francisco J. Martinez, Juan Manuel Gorriz
<span title="2020-07-17">2020</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/u3qqmkiofjejrnpdxh3hdgssm4" style="color: black;">Information Fusion</a> </i> &nbsp;
We provide a review that encompasses (1) an overview of current challenges in multimodal fusion (2) the current medical applications of fusion for specific neurological diseases, (3) strengths and limitations  ...  Multimodal fusion in neuroimaging combines data from multiple imaging modalities to overcome the fundamental limitations of individual modalities.  ...  OCD patients were found to have lower grey matter volumes in specific regions of the brain.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.inffus.2020.07.006">doi:10.1016/j.inffus.2020.07.006</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/32834795">pmid:32834795</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC7366126/">pmcid:PMC7366126</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/3cmhcplb5bf2fgpx3kukifbj74">fatcat:3cmhcplb5bf2fgpx3kukifbj74</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200905045940/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC7366126&amp;blobtype=pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/c6/72/c672fe43b354a25608b78bf4085c49100bbde6e0.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.inffus.2020.07.006"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> elsevier.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7366126" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>
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