Filters








1,913 Hits in 9.3 sec

QUANTIFYING REGIONAL GROWTH PATTERNS THROUGH LONGITUDINAL ANALYSIS OF DISTANCES BETWEEN MULTIMODAL MR INTENSITY DISTRIBUTIONS

Avantika Vardhan, Marcel Prastawa, Sylvain Gouttard, Joseph Piven, Guido Gerig
2012 IEEE International Symposium on Biomedical Imaging  
We propose a framework for analyzing spatiotemporal patterns of brain maturation by quantifying intensity changes in longitudinal MR images.  ...  We use a measure of divergence between a pair of intensity distributions to study the changes that occur within specific regions, as well as between a pair of anatomical regions, over time.  ...  We list the values of τ in CONCLUSIONS We have presented a framework for comparing growth patterns by measuring distances between brain tissue intensity distributions on intensity-normalized image data  ... 
pmid:23958630 pmcid:PMC3744339 fatcat:ppf46rjacvfetcqhyqtisfwplu

Quantifying regional growth patterns through longitudinal analysis of distances between multimodal MR intensity distributions

Avantika Vardhan, Marcel Prastawa, Sylvain Gouttard, Joseph Piven, Guido Gerig
2012 2012 9th IEEE International Symposium on Biomedical Imaging (ISBI)  
We propose a framework for analyzing spatiotemporal patterns of brain maturation by quantifying intensity changes in longitudinal MR images.  ...  We use a measure of divergence between a pair of intensity distributions to study the changes that occur within specific regions, as well as between a pair of anatomical regions, over time.  ...  CONCLUSIONS We have presented a framework for comparing growth patterns by measuring distances between brain tissue intensity distributions on intensity-normalized image data.  ... 
doi:10.1109/isbi.2012.6235765 dblp:conf/isbi/VardhanPGPG12 fatcat:kzcfpzj5xbgqxpigtq7udo2toq

Modeling longitudinal MRI changes in populations using a localized, information-theoretic measure of contrast

Avantika Vardhan, Marcel Prastawa, Anuja Sharma, Joseph Piven, Guido Gerig
2013 2013 IEEE 10th International Symposium on Biomedical Imaging  
Longitudinal MR imaging during early brain development provides important information about growth patterns and the development of neurological disorders.  ...  Our method uses regression in the LogOdds space and an informationtheoretic measure of distance between distributions to capture contrast in a manner that is robust to imaging parameters and without requiring  ...  Analysis of Growth through Contrast We conduct quantitative analysis of growth using these 4D values of contrast.  ... 
doi:10.1109/isbi.2013.6556794 pmid:24443698 pmcid:PMC3892761 dblp:conf/isbi/VardhanPSPG13 fatcat:qwu3onks4vcslk24o7ekbyd6ba

Modeling 4D pathological changes by leveraging normative models

Bo Wang, Marcel Prastawa, Andrei Irimia, Avishek Saha, Wei Liu, S.Y. Matthew Goh, Paul M. Vespa, John D. Van Horn, Guido Gerig
2016 Computer Vision and Image Understanding  
With the increasing use of efficient multimodal 3D imaging, clinicians are able to access longitudinal imaging to stage pathological diseases, to monitor the efficacy of therapeutic interventions, or to  ...  assess and quantify rehabilitation efforts.  ...  open issues related to multimodal image analysis and longitudinal modeling.  ... 
doi:10.1016/j.cviu.2016.01.007 pmid:27818606 pmcid:PMC5094466 fatcat:3ue76cbzrfey3g3q7tejnaq5hm

Development of a Three-Dimensional In Vitro Model for Longitudinal Observation of Cell Behavior: Monitoring by Magnetic Resonance Imaging and Optical Imaging

Klaus Kruttwig, Chantal Brueggemann, Eric Kaijzel, Susanne Vorhagen, Thomas Hilger, Clemens Löwik, Mathias Hoehn
2009 Molecular Imaging and Biology  
A linear relationship of fluorescence intensity with cell aggregate size was found, allowing absolute quantitation of cells in a wide range of cell amounts.  ...  Conclusions: Through the combination of two-dimensional optical imaging and 3D MRI, the position of individual cell aggregates and their corresponding light emission can be detected.  ...  This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original  ... 
doi:10.1007/s11307-009-0289-x pmid:19949979 pmcid:PMC2912723 fatcat:t4fvszafmjg35jvyvkg2tn2cny

Building spatiotemporal anatomical models using joint 4-D segmentation, registration, and subject-specific atlas estimation

Marcel Prastawa, Suyash P. Awate, Guido Gerig
2012 2012 IEEE Workshop on Mathematical Methods in Biomedical Image Analysis  
Estimating anatomical changes in longitudinal studies, especially through magnetic resonance (MR) images, is challenging because of temporal variability in shape (e.g. from growth/atrophy) and appearance  ...  Longitudinal analysis of anatomical changes is a vital component in many personalized-medicine applications for predicting disease onset, determining growth/atrophy patterns, evaluating disease progression  ...  Acknowledgments The work described in this paper is part of the National Alliance for Medical Image Computing (NAMIC), funded by the National Institutes of Health through the NIH Roadmap for Medical Research  ... 
doi:10.1109/mmbia.2012.6164740 dblp:conf/mmbia/PrastawaAG12 fatcat:2fmrktjipnfwfckhgmaeion5m4

Imaging Hallmarks of the Tumor Microenvironment in Glioblastoma Progression

John J. Walsh, Maxime Parent, Adil Akif, Lucas C. Adam, Samuel Maritim, Sandeep K. Mishra, Muhammad H. Khan, Daniel Coman, Fahmeed Hyder
2021 Frontiers in Oncology  
Perfused regions between tumor periphery and core with U87 tumors exhibited higher Fp, but Ktrans of U251 tumors remained lowest at the tumor margin, suggesting primitive vascularization.  ...  Tumor growth was uncorrelated with ve, ADC, and pHe. U87 tumors showed correlated regions of reduced ve and lower ADC (higher cellularity), suggesting ongoing proliferation.  ...  Unique tumor growth patterns were evident between U87 and U251 tumors, with U87 tumors growing to twice the tumor volumes of U251 tumors at the final time point.  ... 
doi:10.3389/fonc.2021.692650 pmid:34513675 pmcid:PMC8426346 fatcat:bzx2tdytsfarvbaakq7gpt2zsy

Biomechanical Analysis of Normal Brain Development during the First Year of Life Using Finite Strain Theory

Jeong Chul Kim, Li Wang, Dinggang Shen, Weili Lin
2016 Scientific Reports  
Combining longitudinal MR imaging and finite strain theory, this study aimed to provide new insights into normal brain development through a biomechanical framework.  ...  Our results revealed anisotropic and inhomogeneous brain growth patterns of the human brain during the first year of life using longitudinal MRI and a biomechanical framework.  ...  Combining longitudinal MR imaging and finite strain theory, this study aimed to provide new insights into normal brain development through a biomechanical framework.  ... 
doi:10.1038/srep37666 pmid:27910866 pmcid:PMC5133553 fatcat:hq2wniz5hrdjxc2erljroiwrv4

Computational neuroanatomy of baby brains: A review

Gang Li, Li Wang, Pew-Thian Yap, Fan Wang, Zhengwang Wu, Yu Meng, Pei Dong, Jaeil Kim, Feng Shi, Islem Rekik, Weili Lin, Dinggang Shen
2018 NeuroImage  
However, infant brain MR images typically exhibit reduced tissue contrast (especially around 6 months of age), large within-tissue intensity variations, and regionally-heterogeneous, dynamic changes, in  ...  normative and aberrant growth.  ...  During the first postnatal year, the brain volume doubles with regionally-heterogeneous growth patterns (Knickmeyer et al., 2008) .  ... 
doi:10.1016/j.neuroimage.2018.03.042 pmid:29574033 pmcid:PMC6150852 fatcat:w2o27wt5afhktd7zoophmhnmi4

Efficient Morphometric Techniques in Alzheimer's Disease Detection: Survey and Tools

Vinutha N., P. Deepa Shenoy, P. Deepa Shenoy, K.R. Venugopal
2016 Neuroscience International  
But in recent years, the main focus of researchers is towards the FBM and SBM to overcome the disadvantage of group analysis that existed in VBM and DBM.  ...  The subject image obtained from the dataset, can be geometrically aligned to the template image through the process of registration.  ...  The corresponding author confirms that all of the other authors have read and approved the manuscript and there are no ethical issues involved.  ... 
doi:10.3844/amjnsp.2016.19.44 fatcat:3zeb2s5pjzfv7mptqi7cy2a3au

Multimodal in vivo Imaging of the Integrated Postnatal Development of Brain and Skull and Its Co-modulation With Neurodevelopment in a Down Syndrome Mouse Model

Sergi Llambrich, Rubèn González, Julia Albaigès, Jens Wouters, Fopke Marain, Uwe Himmelreich, James Sharpe, Mara Dierssen, Willy Gsell, Neus Martínez-Abadías, Greetje Vande Velde
2022 Frontiers in Medicine  
Perinatal GTE-EGCG induced disparate effects and disrupted the magnitude of integration and covariation patterns between brain and skull.  ...  We optimized a multimodal protocol combining in vivo micro-computed tomography (μCT) and magnetic resonance imaging (μMRI) with morphometric analyses and neurodevelopmental tests to longitudinally monitor  ...  To statistically quantify overall differences between WT, TS, WT treated and TS treated mice, we estimated the Procrustes distances between the average shapes of pairs of groups at each stage of development  ... 
doi:10.3389/fmed.2022.815739 pmid:35223915 pmcid:PMC8874331 fatcat:dwwwtf5ivrd6hhwvpahb3yjaoy

MRI of the Neonatal Brain: A Review of Methodological Challenges and Neuroscientific Advances

Jessica Dubois, Marianne Alison, Serena J. Counsell, Hertz‐Pannier Lucie, Petra S. Hüppi, Manon J.N.L. Benders
2020 Journal of Magnetic Resonance Imaging  
Appropriate methodologies then make it possible to explore multiple neurodevelopmental mechanisms in a precise way, and assess changes with age or differences between groups of subjects, particularly through  ...  MR sequences must be adapted to the brains of newborns and infants to obtain relevant good soft-tissue contrast, given the small size of the cerebral structures and the incomplete maturation of tissues  ...  In interactions with the development of cortical regions, structural connectivity develops within the WM, through intense and intertwined processes of growth and maturation during pregnancy and early childhood  ... 
doi:10.1002/jmri.27192 pmid:32420684 fatcat:ttakecloanaupet2ej7uk5nzxi

MRI of metastasis-permissive microenvironments

Marie-France Penet, Zhihang Chen, Zaver M Bhujwalla
2011 Future Oncology  
Cohesive strategies integrating advances in molecular biology and chemistry, with noninvasive multimodality imaging, provide new insights into the role of the tumor microenvironment in promoting metastasis  ...  Keywords imaging; metastasis; microenvironment From all its hallmarks, the unsurpassed ability of cancer cells to adapt and survive during growth and following treatment, coupled with the ability to disseminate  ...  The distance axis on the dendrogram represents the distance or dissimilarity between the two clusters.  ... 
doi:10.2217/fon.11.114 pmid:22044202 pmcid:PMC3235911 fatcat:ow3zgdglnfebbkbbql5ae7b33m

Extended Modality Propagation: Image Synthesis of Pathological Cases

Nicolas Cordier, Herve Delingette, Matthieu Le, Nicholas Ayache
2016 IEEE Transactions on Medical Imaging  
in glioma image synthesis, and iii) illustrated using the output of two different tumor growth models.  ...  An application to Magnetic Resonance Imaging synthesis of glioma-bearing brains is i) validated on the training dataset of a Multimodal Brain Tumor Image Segmentation challenge, ii) compared to the state-of-theart  ...  The impact of this perspective would have to be carefully considered since some tumor patterns might be more or less likely in different brain regions.  ... 
doi:10.1109/tmi.2016.2589760 pmid:27411217 fatcat:ya2awxxqnbhshl77s4um5tbwbm

Individual variability in the human connectome maintains selective cross-modal consistency and shares microstructural signatures [article]

Esin Karahan, Luke Tait, Ruoguang Si, Aysegul Ozkan, Maciek Szul, Jiaxiang Zhang
2021 bioRxiv   pre-print
This pattern is consistent across all modalities at varying degrees as shown by significant alignment between functional and structural connectome variabilities at several clusters of brain regions.  ...  Here, by using multimodal imaging data including diffusion MRI, functional MRI and MEG, we show the consistency of interindividual variation of connectivity across modalities.  ...  distance between white matter voxel and the grey matter region.  ... 
doi:10.1101/2021.04.01.438129 fatcat:o2qdo7lqtfbhdcv7vppknpzwu4
« Previous Showing results 1 — 15 out of 1,913 results