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Assessment of a multi-layered diffuse correlation spectroscopy method for monitoring cerebral blood flow in adults
2016
Biomedical Optics Express
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The method was first validated with phantom experiments. Next, experiments were conducted in a pig model of the adult head with a mean extracerebral tissue thickness of 9.8 ± 0.4 mm. ...
Diffuse correlation spectroscopy (DCS) is a promising technique for brain monitoring as it can provide a continuous signal that is directly related to cerebral blood flow (CBF); however, signal contamination ...
Another possibility to quantify blood flow indices measured by DCS is direct calibration by an all-optical modality [37] . ...
doi:10.1364/boe.7.003659
pmid:27699127
pmcid:PMC5030039
fatcat:5swwr7yalreubgeryvrbi6kccq
Imaging hemodynamic response after ischemic stroke in mouse cortex using visible-light optical coherence tomography
2016
Biomedical Optics Express
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The sO 2 of vessels in the penumbra region also dropped below normal range after focal ischemia. optical imaging system for in vivo investigation of cerebral oxygen delivery and energy metabolism," Biomed ...
Vis-OCT can retrieve blood oxygen saturation (sO 2 ) mapping using intrinsic optical absorption contrast while providing high-resolution anatomical vascular structures at the same time. ...
Pulsinelli, "Continuous measurement of cerebral cortical blood flow by laser-Doppler flowmetry in a rat stroke model," J. Cereb. Blood Flow Metab. 9(5), 589-596 (1989). 17. V. J. Srinivasan, J. Y. ...
doi:10.1364/boe.7.003377
pmid:27699105
pmcid:PMC5030017
fatcat:wggyhncbovdnlfnivltae6ebka
Assessment of the best flow model to characterize diffuse correlation spectroscopy data acquired directly on the brain
2015
Biomedical Optics Express
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Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults," Neurocrit. ...
instead of by the expected random flow model. ...
Verdecchia was supported by a scholarship from a Queen Elisabeth II Graduate Scholarship in Science and Technology (QEII-GSST). ...
doi:10.1364/boe.6.004288
pmid:26600995
pmcid:PMC4646539
fatcat:phxgqzxbonad7luqhjg3bidy5q
Microvascular imaging: techniques and opportunities for clinical physiological measurements
2014
Physiological Measurement
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tumour microenvironment, and quantifying cerebral blood flow. ...
The cauterization process gave rise to a reduction in cerebral blood flow, followed by a transient increase in perfusion. ...
doi:10.1088/0967-3334/35/7/r91
pmid:24910968
fatcat:lsrpnj3l4rgjjmendyoejmqdl4
Abstracts
2013
Cerebrovascular Diseases
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Cerebral autoregulation is an important physiological mechanism that assists in maintaining cerebral blood flow relatively constant in the face of constantly changing blood pressure. ...
The development of transcranial Doppler has allowed us to examine the response of cerebral flow velocity to beat by beat changes in blood pressure. ...
Methods: We conducted a retrospective review, in a middle size clinic (120 beds), in Clínica Alemana de Temuco, involving patients who underwent ST with a protocol of 2 hours, associated to tPA, between ...
doi:10.1159/000351748
pmid:23712294
fatcat:kuw65edukrgkfdsnvwgsbj2r4m
This was the year that was: brain barriers and brain fluid research in 2019
2020
Fluids and Barriers of the CNS
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This editorial highlights advances in brain barrier and brain fluid research published in 2019, as well as addressing current controversies and pressing needs. ...
Topics include recent advances related to: the cerebral endothelium and the neurovascular unit; the choroid plexus, arachnoid membrane; cerebrospinal fluid and the glymphatic hypothesis; the impact of ...
tau and this was reviewed in-depth by Hladky and Barrand [99] . ...
doi:10.1186/s12987-020-00181-9
pmid:32138786
fatcat:ueypzgfddjfsrg5fcccvfitvi4
Joint Meeting 2009 of the Society for Microcirculation and Vascular Biology (GfMVB) and the Swiss Society for Microcirculation (SSM)
2009
Journal of Vascular Research
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Methods: Transient focal cerebral ischemia was induced in G-CSF knock out mice by left middle cerebral artery occlusion (MCAO). ...
P03-P23 rAAV-cotransfection of VEGF-A and PDGF-B induces therapeutic neovascularization in chronic hindlimb ischemia (rabbit) and resolves hibernating myocardium in a chronic pig model: role of vessel ...
In conclusion, these data suggest that lymphatic drainage plays a pivotal role in mounting an adaptive immune response. ...
doi:10.1159/000245770
fatcat:u3zdqn6bcvhlhaqfda4my52jwy
19th Meeting of the European Society of Neurosonology and Cerebral Hemodynamics. Rome, Italy, May10-13, 2014: Abstracts
2014
Cerebrovascular Diseases
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In the carotid sinus, in addition to the red laminar flow a blue coded area -so called flow separation zone -can be observed. ...
Conclusion: Color-coded duplex ultrasonography is a valuable method in neurovascular diagnostics. ...
as anatomic and time resolved contrast-enhanced MRA (TWIST). ...
doi:10.1159/000363090
pmid:24820383
fatcat:klgzz6jqb5cw7apjjr4mzpcjjy
Mechanics of the brain: perspectives, challenges, and opportunities
2015
Biomechanics and Modeling in Mechanobiology
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The multi-disciplinary analysis of these various phenomena and pathologies presents new opportunities and suggests that mechanical modeling is a central tool to bridge the scales by synthesizing information ...
Despite a clear evidence that mechanical factors play an important role in regulating brain activity, current research efforts focus mainly on the biochemical or electro-I'll say that again, E = 2r . ...
A first study evaluated visual evoked potentials in guinea pig optic nerves before and after stretch (Bain and Meaney 2000) . ...
doi:10.1007/s10237-015-0662-4
pmid:25716305
pmcid:PMC4562999
fatcat:fzay725anncctcjtuj2r2f2xfq
Abstracts
2011
Journal of Vascular Research
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PID is associated with cerebral blood flow (CBF) changes due to tight neurovascular coupling. ...
changes in cortical membrane potential and CBF changes by multi-modal imaging of the rat cerebral cortex under multifocal ischemia caused by multiplex embolisation. ...
This research was supported by and UrB of RAS (project 10-1-SP-257). J. Allen, J. R Frame and A. Murray Physiol. ...
doi:10.1159/000332604
fatcat:egmxzxdg6bcyhn7iuw3qmwnjmi
Brain PET Poster Sessions PP01-M01 to PP02-N07
2019
Journal of Cerebral Blood Flow and Metabolism
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Acknowledgements The authors would like to thank A. Leukona, X. Rı´os, V. Salinas for technical support in radiosynthesis and technical assistance in the PET studies. ...
This study was funded by MINECO SAF2014-54070-JIN. Acknowledgements Funding from ANR CYCLOPS (ANR-15-CE17-0020) and RHU MARVELOUS (ANR-16-RHUS-0009) ...
Arterial spin labeling was used to measure cerebral blood flow, dynamic contrast enhanced MRI to measure blood volume, and 18F-FDG-PET to measure cerebral glucose metabolism. ...
doi:10.1177/0271678x19851018
pmid:31265793
pmcid:PMC6610575
fatcat:auejdo6e3rb2pjtxgqq6rkm7ie
25th Conference of the European Society for Microcirculation. Budapest, Hungary, August 26–29, 2008
2008
Journal of Vascular Research
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any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specifi ed fee to the Copyright Clearance Center (see ...
No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by ...
in an increased local cerebral blood flow and a moderately increased density of large vessels resulting in a decrease in local cerebral blood flow. ...
doi:10.1159/000144991
fatcat:3nbmpjrvyvdrxaimpgurvmgl2i
Scientific paper sessions
2009
Neuroradiology
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In MB-EN, cortex isointensity was present on T2WI, a low signal on T1WI with marked enhancement (a central scar-like pattern), and a multinodular appearance. ...
MATERIALS AND METHODS MR examinations and clinical and pathology reports from 4 institutions, for a total of 28 patients with histologically proven diagnosis of MB, were retrospectively analyzed. ...
Perfusion maps of cerebral blood volume (CBV), cerebral blood flow (CBF), and mean transit time were generated by the deconvolution method. ...
doi:10.1007/s00234-009-0561-4
fatcat:o5kffdrey5e7pp6rpqpvepbowy
Noninvasive imaging
2001
Journal of the American College of Cardiology
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In a subgroup of the pts with sinus rhythm (NSR) the LAA-EF was significantly less in pts with clot (31.2 + 13.2 Vs 41.2 + 11.5% p50% diameter stenosis. ...
There are not enough studies properly evaluating LAA function in a large number of patients (pts) with isolated severe MS. ...
Background: We have developed a new color 3D method for quantifying AR flow by subtracting forward mitral from forward Ao flow, which we have tested in a chronic animal model. ...
doi:10.1016/s0735-1097(01)80006-1
fatcat:ghklt3w3zze3le5gwnpbbfvrrm
EUROPEAN SOCIETY OF NEURORADIOLOGY XXXI CONGRESS AND 15TH ADVANCED COURSE GENEVA, 13–16 SEPTEMBER 2006
2006
Neuroradiology
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This stent appears to be a valuable alternative to ballon-expandable coronary stents. O10.4 ...
A pulsatile flow circulation system was used. Embolic clots were produced using pig blood plasma. ...
technique that dynamically resolves the time differences in contrast agent arrival. ...
doi:10.1007/s00234-006-0137-5
pmid:16932977
fatcat:sjmqiubb35gx7kxn4uofb732cq
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