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Yi Qi Qing Re Gao formula ameliorates puromycin aminonucleoside-induced nephrosis by suppressing inflammation and apoptosis

Yumin Wen, Yongli Zhan, Huijie Liu, Tingting Zhao, Liping Yang, Haojun Zhang, Xi Dong, Ping Li
2015 BMC Complementary and Alternative Medicine  
Yi Qi Qing Re Gao (YQQRG) formula is a traditional Chinese herbal medicine used to treat chronic nephritis.  ...  Yi Qi Qing Re Gao (YQQRG) formula, a traditional Chinese herbal medicine, has been used to treat chronic nephritis for over 2 decades in Guang'anmen Hospital, Beijing.  ... 
doi:10.1186/s12906-015-0673-9 pmid:26014479 pmcid:PMC4443657 fatcat:jcrf6xtffvclhizg6egqkl4m74

Yi Qi Qing Re Gao Formula Ameliorates Puromycin Aminonucleoside-induced Nephrosis by Suppressing Inflammation and Apoptosis

Yumin Wen, Tingting Zhao, Haojun Zhang, Ping Li
2015 Hong Kong Journal of Nephrology  
Objective: Yi Qi Qing Re Gao (YQQRG) formula is a traditional Chinese herbal medicine used to treat chronic nephritis.  ...  S78 Inflammation and Fibrosis 0095 Yi Qi Qing Re Gao Formula Ameliorates Puromycin Aminonucleosideinduced Nephrosis by Suppressing Inflammation and Apoptosis  ... 
doi:10.1016/j.hkjn.2015.09.100 fatcat:vrpna3czbvg55dj2ngoxd2w2fa

Yi Qi Qing Re Gao Attenuates Podocyte Injury and Inhibits Vascular Endothelial Growth Factor Overexpression in Puromycin Aminonucleoside Rat Model

Yongli Zhan, Liping Yang, Yumin Wen, Huijie Liu, Haojun Zhang, Bin Zhu, Wenbing Han, Yanting Gu, Xueyan Sun, Xi Dong, Tingting Zhao, Huixia Ma (+1 others)
2014 Evidence-Based Complementary and Alternative Medicine  
Yi Qi Qing Re Gao (YQQRG) has been used to treat proteinuria for more than two decades.  ... 
doi:10.1155/2014/375986 pmid:24963322 pmcid:PMC4055581 fatcat:itswofmsibfebh6vj4f7qosxua

Yi Qi Qing Re Gao-containing serum inhibits lipopolysaccharide-induced rat mesangial cell proliferation by suppressing the Wnt pathway and TGF-β1 expression

2016 Experimental and Therapeutic Medicine  
The aim of the present study was to investigate the effect of Yi Qi Qing Re Gao-containing serum (YQ-S) on rat mesangial cell (MC) proliferation and to investigate the underlying mechanism.  ...  OD, optical density; LPS, lipopolysaccharide; YQ-S, Yi Qi Qing Re Gao-containing serum; For-S, fosinopril-containing serum.  ...  LPS, lipopolysaccharide; YQ-S, Yi Qi Qing Re Gao-containing serum; For-S, fosinopril-containing serum; TGF-β1, transforming growth factor-β1.  ... 
doi:10.3892/etm.2016.3027 pmid:27073458 pmcid:PMC4812120 fatcat:6po4kyh6qfforbrctpqpz7wzsu

Nonaliquot numbers

2011 Publicationes mathematicae (Debrecen)  
For any positive integer n, let σ(n) be the sum of the positive divisors of n. It is known that almost all odd numbers can be represented in the form σ(m) − m for some natural number m. In this paper, we prove that the number of even numbers which are less than x and not of the form σ(m) − m is at least 0.06x + o(x). This improves the lower bound 1 48 x + o(x) obtained by Banks and Luca.
doi:10.5486/pmd.2011.4820 fatcat:ijnuod2iljgnhn6fkiye7fdb2y

Spatiotemporal variation of vegetation in the lower reaches of Tarim River

Qing GAO, Kurban ALISHIR, Hao XIAO, Qing GAO, Kurban ALISHIR, Hao XIAO
2019 自然资源学报  
Spatiotemporal variation of vegetation in the lower reaches of Tarim River GAO Qing 1,2 , ALISHIR Kurban 1 , XIAO Hao 1,2 (1.  ... 
doi:10.31497/zrzyxb.20190315 fatcat:547jp2qgtzhnhe52xdlkjnsthm

Quantum Graph Convolutional Neural Networks [article]

Jin Zheng, Qing Gao, Yanxuan Lv
2021 arXiv   pre-print
At present, there are a large number of quantum neural network models to deal with Euclidean spatial data, while little research have been conducted on non-Euclidean spatial data. In this paper, we propose a novel quantum graph convolutional neural network (QGCN) model based on quantum parametric circuits and utilize the computing power of quantum systems to accomplish graph classification tasks in traditional machine learning. The proposed QGCN model has a similar architecture as the classical
more » ... graph convolutional neural networks, which can illustrate the topology of the graph type data and efficiently learn the hidden layer representation of node features as well. Numerical simulation results on a graph dataset demonstrate that the proposed model can be effectively trained and has good performance in graph level classification tasks.
arXiv:2107.03257v1 fatcat:mvz3hf7hgvhsbmiwqc6lpivxmu

Born to Win: Reproductive Health Policy and Urban Education Returns in China

Qing Gao, Qing Gao, Xiu-Xiu Ren, Wei-Lan Yan, Ai-Hua Wang, Wei-Hua Zhang, Wei-Hua Zhang
2022 Frontiers in Public Health  
This study explores the relationship between China's reproductive health policy and the rate of return on urban education by using fixed-effect, mediating-effect, and breakpoint regression models. The authors study the impact of China's reproductive health policy on individual years of education, income, return on education, the impact of reproductive health policy on population health, and overall human development. The empirical results show that the implementation of China's reproductive
more » ... th policy can improve the rate of return on urban education and increase the average length of education of urban residents by 0.29 years. Under the breakpoint regression model, the educational return rate of urban residents is approximately 12.2% higher than the ordinary least squares (OLS) estimate. China's reproductive health policy has significantly promoted the return rate of residents' education and simultaneously effectively promoted the income of urban residents. With the development of the economy, the government should properly adjust reproductive health policies and improve the population health rate so that the adjustment of reproductive health policies can comprehensively promote the health of residents of all ages. The overall relaxation of family restrictions on children's human capital investment will likely reduce the negative impact of the overall relaxation of family planning, not only improving the health of the population but also contributing to sustainable economic development.
doi:10.3389/fpubh.2022.807794 pmid:35309191 pmcid:PMC8927718 doaj:e6bd5af76463411c981fb85e55aeb222 fatcat:fvdb4w3lu5axxmmyuuhggoo4lq

GABA in Paraventricular Nucleus Regulates Adipose Afferent Reflex in Rats

Lei Ding, Run Gao, Xiao-Qing Xiong, Xing-Ya Gao, Qi Chen, Yue-Hua Li, Yu-Ming Kang, Guo-Qing Zhu, William D Phillips
2015 PLoS ONE  
Chemical stimulation of white adipose tissue (WAT) induces adipose afferent reflex (AAR), and thereby causes a general sympathetic activation. Paraventricular nucleus (PVN) is important in control of sympathetic outflow. This study was designed to investigate the role of γ-aminobutyric acid (GABA) in PVN in regulating the AAR. Methodology/Principal Findings Experiments were carried out in anesthetized rats. Renal sympathetic nerve activity (RSNA) and mean arterial pressure (MAP) were
more » ... y recorded. AAR was evaluated by the RSNA and MAP responses to electrical stimulation of the right epididymal WAT (eWAT) afferent nerve. Electrical stimulation of eWAT afferent nerve increase RSNA. Bilateral microinjection of the GABA A receptor agonist isoguvacine or the GABA B receptor agonist baclofen attenuated the AAR. The effect of isoguvacine on the AAR was greater than that of baclofen. The GABA A receptor antagonist gabazine enhanced the AAR, while the GABA B receptor antagonist CGP-35348 had no significant effect on the AAR. Bilateral PVN microinjection of vigabatrin, a selective GABA-transaminase inhibitor, to increase endogenous GABA levels in the PVN abolished the AAR. The inhibitory effect of vigabatrin on the AAR was attenuated by the pretreatment with gabazine or CGP-35348. Pretreatment with combined gabazine and CGP-35348 abolished the effects of vigabatrin.
doi:10.1371/journal.pone.0136983 pmid:26317425 pmcid:PMC4552845 fatcat:4qh3y5vmjrf7xlgpmi32ymmgou

Ultrafast third-order optical nonlinearities in DMSO

Degui Kong Degui Kong, Guanghong Ao Guanghong Ao, Yachen Gao Yachen Gao, Qing Chang Qing Chang, Hong'an Ye Hong'an Ye
2012 Chinese Optics Letters (COL)  
The third-order optical nonlinearities of dimethyl sulfoxide (DMSO) are investigated using the optical Kerr effect (OKE) and Z-scan techniques with femtosecond pulses. We are able to fit the OKE signal theoretically by convolving the autocorrelation of the incident pulse intensity profile with the impulse responses of the samples, illustrating the instantaneous nonlinear response of DMSO. We verify that the purely electronic cloud distortion causes the observed signal for DMSO. The Z-scan
more » ... que is used to estimate the third-order susceptibility of DMSO, which is about a quarter of that for CS2 and mainly comes from the nonlinear refraction with an intensity of less than 140 GW/cm 2 .
doi:10.3788/col201210.111601 fatcat:bcqlke6mgfa5dpiilywsathfqy

Treatment of diabetes in children

2016 Experimental and Therapeutic Medicine  
Type 1 diabetes mellitus (T1D) and type 2 diabetes (T2D) mellitus are on the increase in children and adolescents. An increase in T2D is linked to the increasing rates of obesity in children. Usually, in both children and adults, T1D is treated with insulin while T2D is treated with metformin. There are other classes of drugs that are under assessment for their safety and efficacy in relation to pediatric patients. Most of these new drugs, however, have not been studied in children. Thus, the
more » ... pertoire of drugs that are available to treat diabetes in children is limited. In this review, we outline the current pathology and treatment and future therapies of T1D mellitus and T2D mellitus in children. Contents 1. Introduction 2. Pathology 3. Diagnosis 4. Primary treatment of type 2 diabetes 5. Insulin treatment in type 2 diabetes 6. Alternative drug treatments in childhood type 2 diabetes 7. Treatment of type 1 diabetes 8. Lifestyle modifications 9. Investigational treatments 10. Conclusion
doi:10.3892/etm.2016.3039 pmid:27073417 pmcid:PMC4812517 fatcat:rscgae4nbbau3kjcdmd2f2agpi

Structure transformation and magnetisms in Ho2Ni7-xFex compounds

Yang Yu-Qi, Gao Qing-Qing, Li Guan-Nan
2013 Wuli xuebao  
Based on the composite compounds Ho 2 Ni 7−x Fe x (x = 0-3.0), a method of describing the structure transition from rhombohedral to hexagonal is discussed in terms of free electron concentration. The transition is investigated by X-ray powder diffraction and magnetic analysis. The compounds crystallize into the rhombohedral Gd 2 Co 7 -type structure for x = 0-0.5 and into the hexagonal Ce 2 Ni 7 -type structure for x = 0.5-2.5. The values of lattice parameters a and c of the Ho 2 Ni 7−x Fe x
more » ... pounds increase with the addition of Fe, and the saturation magnetization M s decreases with Fe content increasing at a rate of dM s /dx = −2, manifesting antiparallel alignments of the Fe and Ho moment. The higher the free electron concentration, the stabler the rhombohedral structure is, otherwise the hexagonal structure is stabler, which provides a meaningful parameter to distinguish the two allotropies in composite structure intermetallics.
doi:10.7498/aps.62.016103 fatcat:kli5x75lt5aftjt7eyvz3ndjk4

Artemisinin mimics nitric oxide to reduce adipose weight by targeting mitochondrial complexes [article]

Qian Gao, Jiang He, Tao Liao, Yan-Ping Chen, Li-Li Tan, Ji-Da Zhang, Chang-Qing Li, Qing Zeng, Qi Wang, Shui-Qing Huang, Xin-An Huang, Qin Xu (+1 others)
2017 bioRxiv   pre-print
It remains obscure how to medically manage visceral obesity that predisposes metabolic disorders. Here, we show for the first time that a trace amount of artemisinin (0.25 mg/kg) reduces adipose weight in an inflammatory obese mouse model induced by a high-fat diet with lipopolysaccharide (HFD+LPS). HFD+LPS trigger pro-inflammatory responses, upregulate NOS2 expression, elicit potent nitric oxide (NO) burst, and reinforce adipose mitochondrial dysfunctions that facilitate adipogenesis for
more » ... al weight gain. By targeting mitochondrial complexes, artemisinin resembles the NO donor nitroglycerin to exert anti-inflammatory effects, downregulate NOS2 expression, maintain stable NO release, and augment adipose mitochondrial functions that necessitate adipolysis for visceral weight loss. Taken together, artemisinin plays adipose weight-reducing roles by rectifying inflammation-driven mitochondrial dysfunctions.
doi:10.1101/157396 fatcat:5kvrr5xl5bcehdwiqljy2twwri

Tetraaquadiazidocobalt(II) 3,3′-dicarboxylato-1,1′-ethylenedipyridinium

Yan-Qing Wen, Chun-Yan Tian, En-Qing Gao
2010 Acta Crystallographica Section E  
E66, m1566-m1567 [] Tetraaquadiazidocobalt(II) 3,3′-dicarboxylato-1,1′-ethylenedipyridinium Yan-Qing Wen, Chun-Yan Tian and En-Qing Gao S1.  ... 
doi:10.1107/s1600536810046143 pmid:21589255 pmcid:PMC3011402 fatcat:asafdqjd4fcftps26qtk2ln7we

AdvHaze: Adversarial Haze Attack [article]

Ruijun Gao, Qing Guo, Felix Juefei-Xu, Hongkai Yu, Wei Feng
2021 arXiv   pre-print
In recent years, adversarial attacks have drawn more attention for their value on evaluating and improving the robustness of machine learning models, especially, neural network models. However, previous attack methods have mainly focused on applying some l^p norm-bounded noise perturbations. In this paper, we instead introduce a novel adversarial attack method based on haze, which is a common phenomenon in real-world scenery. Our method can synthesize potentially adversarial haze into an image
more » ... ased on the atmospheric scattering model with high realisticity and mislead classifiers to predict an incorrect class. We launch experiments on two popular datasets, i.e., ImageNet and NIPS 2017. We demonstrate that the proposed method achieves a high success rate, and holds better transferability across different classification models than the baselines. We also visualize the correlation matrices, which inspire us to jointly apply different perturbations to improve the success rate of the attack. We hope this work can boost the development of non-noise-based adversarial attacks and help evaluate and improve the robustness of DNNs.
arXiv:2104.13673v1 fatcat:u4g435yyonfenoki5dcufwnlbe
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