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We caught up with co-first authors Qiang Zhu and Marçal Gallemí and their supervisor Eva Benková, Professor at the Institute of Science and Technology Austria in Klosterneuberg, to find out more about ...doi:10.1242/dev.183590 pmid:31515442 fatcat:2sxokfftafa4vgn6r4elcaac4q
Proceedings 2003 VLDB Conference
Similarity searches in multidimensional Nonordered Discrete Data Spaces (NDDS) are becoming increasingly important for application areas such as genome sequence databases. Existing indexing methods developed for multidimensional (ordered) Continuous Data Spaces (CDS) such as R-tree cannot be directly applied to an NDDS. This is because some essential geometric concepts/properties such as the minimum bounding region and the area of a region in a CDS are no longer valid in an NDDS. On the otherdoi:10.1016/b978-012722442-8/50061-6 dblp:conf/vldb/QianZXP03 fatcat:xyifmtfk4bhmtkrobfpiuggnxi
more »... nd, indexing methods based on metric spaces such as M-tree are too general to effectively utilize the data distribution characteristics in an NDDS. Therefore, their retrieval performance is not optimized. To support efficient similarity searches in an NDDS, we propose a new dynamic indexing technique, called the ND-tree. The key idea is to extend the relevant geometric concepts as well as some indexing strategies used in CDSs to NDDSs. Efficient algorithms for ND-tree construction are presented. Our experimental results on synthetic and genomic sequence data demonstrate that the performance of the ND-tree is significantly better than that of the linear scan and M-tree in high dimensional NDDSs.
Microalgal heterotrophic cultivation is an emerging technology that can enable producing high cell-density algal cell cultures, which can be coupled with photoautotrophic cultivation for valuable chemicals such as lipids manufacturing. However, how the heterotrophically grown algal cells respond to the lipid-inducing conditions has not been fully elucidated so far. In this study, when the heterotrophically grown Scenedesmus acuminatus cells were subjected to the high light (HL) anddoi:10.3389/fbioe.2021.638726 pmid:34095093 pmcid:PMC8176925 doaj:a8ff1a607de54ccc90a9c7d953e07d3b fatcat:55evgy6esbbd7gegworsqjzbx4
more »... ted (NL) conditions, both the biomass and lipid productivity were enhanced as compared to that of the photoautotrophically grown counterparts. The chlorophyll a fluorometry analysis showed that the Fv/Fm and Y(II) of the heterotrophically grown cells subjected to the HL and NL conditions was recovered to the maximum value of 0.75 and 0.43, respectively, much higher than those of the photoautotrophically grown cells under the same stress conditions. Transcriptomic analysis revealed that heterotrophically grown cells fully expressed the genes coding for the photosystems proteins, including the key photoprotective proteins D1, PsbS, light-harvesting-complex (LHC) I and LHC II. Meanwhile, downregulation of the carotenoid biosynthesis and upregulation of the glycolysis/gluconeogenesis, tricarboxylic acid (TCA) cycle and oxidative phosphorylation pathways were observed when the heterotrophically grown cells were subjected to the HL and N-limited conditions for lipid production. It was deduced that regulation of these pathways not only enhanced the light utilization but also provided the reducing power and ATP by which the biomass accumulation was significantly elevated. Besides, upregulation of the acetyl-CoA carboxylase/biotin carboxylase, digalactosyl diacylglycerol synthase and diacylglycerol acyltransferase 2 encoding genes may be attributable to the enhanced lipid production. Understanding the cellular responses during the trophic transition process could guide improvement of the strength of trophic transition enhancing mic [...]
ZHU Qiang 1 , LI Feng 1 , LIU Xiao-jie 2 (1. Food Security and Strategy Research Center, Nanjing University of Finance & Economics, Nanjing 210023, China; 2. ... [ZHU Q, LI F, WANG J Q. A comparative study on the contents of food education in primary schools in the United States and Japan. Foreign Primary and Secondary Education, 2019, (2): 21-26.]  石冢左玄. ...doi:10.31497/zrzyxb.20200908 fatcat:mg3htny73rehfjty5q6h4b2iz4
*Correspondence: Lan Jia, email@example.com; Qiang Zheng, firstname.lastname@example.org ... Reviewed by: Chao-Guo Yan, Yangzhou University, China Bing Lu, Nantong University, China Copyright © 2022 Shen, Zhang, Zhu, Ma, He, Zhu, Jia and Zheng. ...doi:10.3389/fchem.2022.855352 pmid:35308786 pmcid:PMC8924036 doaj:2093f2c908ce460fb007780f54e37985 fatcat:hywnztmggfdvzbmsj2bsun3p5e
By using the partial transpose and realignment method,we study the time evolution of the bound entanglement under the bilinear-biquadratic Hamiltonian. For the initial Horodecki's bound entangled state, it keeps bound entangled for some time, while for the initial bound entangled states constructed from the unextendable product basis, they become free once the time evolution begins. The time evolution provides a new way to construct bound entangled states, and also gives a method to free bound entanglement.arXiv:quant-ph/0611177v1 fatcat:ekz3q4rx55hrjpgqjprrvgnlsm
Fabricating experimental pictures in research work is a serious academic misconduct, which should better be detected in the reviewing process. However, due to large number of submissions, the detection whether a picture is fabricated or reused is laborious for reviewers, and sometimes is indistinct with human eyes. A tool for detecting similarity between images may help to alleviate this problem. Some methods based on local feature points matching work for most of the time, while these methodsarXiv:2002.03720v1 fatcat:fa4wz7aegrfsnijfi5eewi67jm
more »... ay result in mess of matchings due to ignorance of global relationship between features. We present a framework to detect similar, or perhaps fabricated, pictures with the graph matching techniques. A new iterative method is proposed, and experiments show that such a graph matching technique is better than the methods based only on local features for some cases.
<p>Vehicle detection is one of the key techniques of intelligent transportation system with high requirements for accuracy and real-time. However, the existing algorithms suffer from the contradiction between detec-tion speed and detection accuracy, and weak generalization ability. To address these issues, an improved vehicle detection algorithm is presented based on the You Only Look Once (YOLO). On the one hand, an efficient feature extraction network is restructured to speed up the featuredoi:10.53106/199115992022083304006 fatcat:qvouvdpfhrauzkm6jc4yz7iziq
more »... ansfer of the object, and re-use the feature information extracted from the input image. On the other hand, considering that the fewer pixels are occupied for the smaller objects, a novel feature fusion network is designed to fuse the seman-tic information and representation information extracted by different depth feature extraction layers, and ultimately improve the detection accuracy of small and medium objects. Experiment results indicate that the mean Average Precision (mAP) of the proposed algorithm is up to 93.87%, which is 11.51%, 18.56% and 20.42% higher than that of YOLOv3, CornerNet, and Faster R-CNN, respectively. Furthermore, its detection speed can meet the real-time requirement of practical application basically with 49.45 frames per second.</p> <p> </p>
In knowledge grounded conversation, domain knowledge plays an important role in a special domain such as Music. The response of knowledge grounded conversation might contain multiple answer entities or no entity at all. Although existing generative question answering (QA) systems can be applied to knowledge grounded conversation, they either have at most one entity in a response or cannot deal with out-of-vocabulary entities. We propose a fully data-driven generative dialogue system GenDS thatarXiv:1709.04264v1 fatcat:rvjzxgf7hfbvrl4uz33pioovy4
more »... s capable of generating responses based on input message and related knowledge base (KB). To generate arbitrary number of answer entities even when these entities never appear in the training set, we design a dynamic knowledge enquirer which selects different answer entities at different positions in a single response, according to different local context. It does not rely on the representations of entities, enabling our model deal with out-of-vocabulary entities. We collect a human-human conversation data (ConversMusic) with knowledge annotations. The proposed method is evaluated on CoversMusic and a public question answering dataset. Our proposed GenDS system outperforms baseline methods significantly in terms of the BLEU, entity accuracy, entity recall and human evaluation. Moreover,the experiments also demonstrate that GenDS works better even on small datasets.
In this paper, the geometric phase of thermal state in hydrogen atom under the effects of external magnetic field is considered. Especially the effects of the temperature upon the geometric phase is discussed. Also we discuss the time evolution of entanglement of the system. They show some similar behaviors.arXiv:quant-ph/0605078v1 fatcat:7xcxjfeh2nhvnbdju7g2wwslbe
AUTHOR INFORMATION Corresponding Author *Qiang Zhu (email@example.com) Support information The C-ADP potential A general-purpose interatomic potential has been developed for carbon simulation. ... Author Contributions & These authors contributed equally: Sheng-cai Zhu, Xiao-zhi Yan and Jin Liu. ...arXiv:2003.06110v1 fatcat:clynpzzplvh27oartrzqiadmcm
An analytical model for calculating the propagation time of shock wave in a wave shaper is presented in this study. The calculated results show that the contours of three typical detonation waves, such as conical detonation wave, spherical detonation wave, and planar detonation wave, can be formed in the main charge by changing the thickness of wave shaper. The results show that the planar detonation wave do better than the conical detonation and the spherical detonation wave in increasing thedoi:10.1016/j.dt.2016.01.002 fatcat:buosaxb7djgktn3zw2wy6ysk44
more »... ength-diameter ratio of explosively-formed projectiles (EFP) and keep the nose of EFP integrated. The detonation wave can increase the length-diameter ratio of EFP when the wave shaper has the suitable thickness.
Tumor metastasis is the leading cause of death in patients with advanced gastric cancer (GC). Limited therapeutic regimens are available for this condition, which is associated with a poor prognosis, and the mechanisms underlying tumor metastasis remain unclear. In the present study, increased histone methyltransferase G9A expression in GC tissues correlated with advanced stage and shorter overall survival, and in vitro and in vivo experiments revealed that G9A promoted tumor invasion anddoi:10.1038/s41419-018-0322-6 pmid:29449539 pmcid:PMC5833452 fatcat:kom25fdve5ajdm7nw6wvqa6cum
more »... asis. Moreover, we observed that Reg IV induced G9A via the p-ERK/p-SP1 pathway. SP1 directly binds the G9A promoter and enhances G9A expression, and upregulated G9A then forms a transcriptional activator complex with P300 and GR, thereby promoting ITGB3 expression induced by dexamethasone (DEX) and contributing to GC metastasis. However, the G9A-mediated increase in ITGB3 expression was not dependent on the SET domain and methyltransferase activity of G9A. This study demonstrates that G9A is an independent prognostic marker and promotes metastasis in GC, thus suggesting that it may be a tumor biomarker and potential therapeutic target in GC.
The unexpected aircraft failure is one of the main disruption factors that cause flight irregularity. The aircraft schedule recovery is a challenging problem in both industrial and academic fields, especially when aircraft restoration time is uncertain, which is often ignored in previous research. This paper established a two-stage stochastic recovery model to deal with the problem. The first stage model was a resource assignment model on aircraft schedule recovery, with the objective functiondoi:10.1155/2015/680609 fatcat:mf7xc75n6bffdemqdhmc5wvtmy
more »... f minimizing delay and cancellation cost. The second stage model used simple retiming strategy to adjust the aircraft routings obtained in the first stage, with the objective function of minimizing the expected cost on recourse decision. Based on different scenarios of restoration time, the second stage model can be degenerated as several linear models. A stochastic Greedy Simulated Annealing algorithm was designed to solve the model. The computational results indicate that the proposed stochastic model and algorithm can effectively improve the feasibility of the recovery solutions, and the analysis of value of stochastic solution shows that the stochastic model is worthy of implementation in real life.
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