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Augmentation index is not a proxy for wave reflection magnitude: mechanistic analysis using a computational model

Maarten H.G. Heusinkveld, Tammo Delhaas, Joost Lumens, Wouter Huberts, Bart Spronck, Alun D. Hughes, Koen D. Reesink
2019 Journal of applied physiology  
Aortic blood pressure waveforms were characterized using AIx and the reflected wave pressure amplitude (p̂bw, obtained using wave separation analysis).  ...  We conclude that the AIx reflects both cardiac and vascular properties and should not be considered an exclusively vascular parameter.NEW & NOTEWORTHY We used a state-of-the-art computational model to  ...  arrival time.  ... 
doi:10.1152/japplphysiol.00769.2018 pmid:31161882 pmcid:PMC6711407 fatcat:qtihs5fr7zagtoaagrqgorsf7i

Pulse transit time estimation of aortic pulse wave velocity and blood pressure using machine learning and simulated training data

Janne M. J. Huttunen, Leo Kärkkäinen, Harri Lindholm, Daniel A Beard
2019 PLoS Computational Biology  
In particular, we carry out theoretical assessment of estimating aortic pulse wave velocity, diastolic and systolic blood pressure and stroke volume using pulse transit/arrival timings derived from photopletyshmography  ...  For instance, aortic pulse wave velocity can be estimated with a high accuracy (r > 0.9) when photopletyshmography is measured from left carotid artery using a combination of foot-to-foot pulse transmit  ...  The estimation of blood pressure from arrival of pulse waves has also been largely studied; see e.g. [6, 9, 10] .  ... 
doi:10.1371/journal.pcbi.1007259 pmid:31415554 pmcid:PMC6711549 fatcat:jwz37le2xfcs7gk3ortixle4pm

Studies Made by Simulating Systole at Necropsy

ISAAC STARR
1959 Circulation  
to changes in direction and velocity of blood in the vessels.  ...  But one would expect that during a brief interval between the onset of ejection and the arrival of important amounts of blood at the aortic arch and the curve of the pulmonary artery, the ballistocardiogram  ...  Observations of the pulse, the blood pressure, and the ballistocardiogram comprise the only methods that at this time give any promise of affording doctors a routine estimate of the cardiac strength of  ... 
doi:10.1161/01.cir.20.1.74 pmid:13663196 fatcat:2dllalyu2rbi7o32hpto777gai

Table of Contents

2021 IEEE Transactions on Biomedical Engineering  
Hook, and H. Park 2798 Pulse Arrival Time Segmentation Into Cardiac and Vascular Intervals -Implications for Pulse Wave Velocity and Blood Pressure Estimation . . . . . . . F. Beutel, C. Van Hoof, X.  ...  Theranostic Wearable Device With Real-Time Vital Monitoring and Auto-Adjustable Compression Level for Venous Thromboembolism . . . . . . Z. Zhang, R. Zhang, C.-W. Chang, Y. Guo, Y.-W. Chi, and T.  ... 
doi:10.1109/tbme.2021.3097626 fatcat:3nydg6yavzgdpgsi2rgjdzv2pi

The role of ventricular-arterial coupling in cardiac disease and heart failure: assessment, clinical implications and therapeutic interventions. A consensus document of the European Society of Cardiology Working Group on Aorta & Peripheral Vascular Diseas

Ignatios Ikonomidis, Victor Aboyans, Jacque Blacher, Marianne Brodmann, Dirk L. Brutsaert, Julio A. Chirinos, Marco De Carlo, Victoria Delgado, Patrizio Lancelotti, John Lekakis, Dania Mohty, Petros Nihoyannopoulos (+12 others)
2019 European Journal of Heart Failure  
Therefore, the measurement of each component of this ratio or of novel more sensitive markers of myocardial (e.g. global longitudinal strain) and arterial function (e.g. pulse wave velocity) may better  ...  In this consensus document, we describe the pathophysiology, the methods of assessment as well as the clinical implications of VAC in cardiac diseases and heart failure.  ...  DBP, diastolic blood pressure; LV, left ventricular; PP, pulse pressure; SBP, systolic blood pressure.  ... 
doi:10.1002/ejhf.1436 pmid:30859669 fatcat:2r62r7cmujc4bhehzb23coftq4

Abnormal Wave Reflections and Left Ventricular Hypertrophy Late After Coarctation of the Aorta RepairNovelty and Significance

Michael A. Quail, Rebekah Short, Bejal Pandya, Jennifer A. Steeden, Abbas Khushnood, Andrew M. Taylor, Patrick Segers, Vivek Muthurangu
2017 Hypertension  
, pulse wave velocity, and wave reflections.  ...  Patients had reduced total arterial compliance, increased pulse wave velocity, and larger backward compression waves compared with controls.  ...  These data provide central blood pressure, systemic vascular resistance, TAC, local pulse wave velocity, and wave reflections.  ... 
doi:10.1161/hypertensionaha.116.08763 pmid:28115510 pmcid:PMC5295491 fatcat:yqumibvkyvci7awmmagzypn3wq

Advances in arterial stiffness assessment

Evelien Hermeling, Robert S. Reneman, Arnold P.G. Hoeks, Koen D. Reesink
2011 Artery Research  
Our work shows that pressure dependency of arterial stiffness can and should be accounted for to evaluate its implication for pressure augmentation and wave separation analysis.  ...  To circumvent these problems, we developed a technique to measure pulse wave velocity (PWV) locally using multiple M-line ultrasound.  ...  In addition, with increased PWV reflections will arrive earlier in the cardiac cycle and the PWV estimated may be subject to interference of reflected waves.  ... 
doi:10.1016/j.artres.2011.10.003 fatcat:7xbbp7ghy5hxlchq2rnffppkxe

Pressure Dependency of Retinal Arterial Pulse Wave Velocity in the Rat

Mahdieh Rezaeian, Dana Georgevsky, S. Mojtaba Golzan, Stuart Graham, Alberto Avolio, Mark Butlin
2020 Artery Research  
Keywords Retinal artery small vessel arterial stiffness pressure dependence pulse wave velocity A B S T R A C T Purpose: The retinal vasculature provides unique in vivo access to the microcirculation and  ...  presents the possibility of measuring small artery (retinal) stiffness using pulse wave velocity (PWV).  ...  AUTHORS' CONTRIBUTION MB, AA and SG were responsible for the study conceptualization and writing (review and editing) the manuscript. MR, DG and MB did the data collection and curation.  ... 
doi:10.2991/artres.k.200201.001 fatcat:hcta63ei2zbrphl36tmi7j6ize

White Matter Hyperintensities: Use of Aortic Arch Pulse Wave Velocity to Predict Volume Independent of Other Cardiovascular Risk Factors

Kevin S. King, Ke Xun Chen, Keith M. Hulsey, Roderick W. McColl, Myron F. Weiner, Paul A. Nakonezny, Ronald M. Peshock
2013 Radiology  
To evaluate the relationship between pulse wave velocity (PWV) from the aortic arch and subsequent cerebral microvascular disease independent of other baseline cardiovascular risk factors among the participants  ...  The optimal predictor variables of subsequent WMH volume adjusted for sex and ethnicity included aortic arch PWV, age, systolic blood pressure, hypertension treatment, and congestive heart failure.  ...  Acknowledgment: We thank Akshay Goel for assistance with manuscript revision. Disclosures of Conflicts of Interest: K.S.K. No relevant conflicts of interest to disclose. K.X.C.  ... 
doi:10.1148/radiol.13121598 pmid:23392429 pmcid:PMC3662900 fatcat:hshzzhk43fbsfhsd52ktwobreu

Velocity/Pressure Response Curve Characterization of the Arterial Path of the P3 Iliac Reflection During Hemorrhage Simulation

Martin C Baruch, Darren ER Warburton, Shannon SD Bredin, Anita Cote, David W. Gerdt, Charles M. Adkins
2012 Annual Review of Chaos Theory, Bifurcations and Dynamical Systems  
A new approach to tracking blood pressure, and pulse pressure specifically is presented that is based on a new form of pulse pressure wave analysis called Pulse Decomposition Analysis (PDA).  ...  Furthermore the comparison of experimental and model predictions provides insight into the pressure/velocity responses of the different arterial segments that the iliac reflection pulse (P3) traverses.  ...  Acknowledgement: This work was supported by the Office of Naval Research and the National Institutes of Health for portions of this research through contract N00014-09-M-0146 and grant 1R43HL087476-01A1  ... 
doaj:76cd40c9971a4431b6fbf1e49c955ecd fatcat:mhwqtsqr6nbjtblkas44czbcvm

Recommendations for Improving and Standardizing Vascular Research on Arterial Stiffness

Raymond R. Townsend, Ian B. Wilkinson, Ernesto L. Schiffrin, Alberto P. Avolio, Julio A. Chirinos, John R. Cockcroft, Kevin S. Heffernan, Edward G. Lakatta, Carmel M. McEniery, Gary F. Mitchell, Samer S. Najjar, Wilmer W. Nichols (+2 others)
2015 Hypertension  
blood pressure level and held constant for about10 seconds to record the pulse waves.  ...  Bramwell-Hill modeling for local aortic pulse wave velocity estimation: a validation study with velocity-encoded cardiovas- cular magnetic resonance and invasive pressure assessment.  ...  Zc Characteristic aortic impedance (also called Zo; measures aortic pressure-flow relationship; ((mmHg*sec)/mL)  ... 
doi:10.1161/hyp.0000000000000033 pmid:26160955 pmcid:PMC4587661 fatcat:xpvoleh6s5b43fdrbnsje3ccnq

Carotid artery longitudinal wall motion: regulatory factors and implications for arterial health

Jason S. Au
2018 Applied Physiology, Nutrition and Metabolism  
We demonstrated that CALM is partly controlled through the forward blood velocity wave and left ventricular rotation of the heart, and that diastolic CALM is uniquely related to aging and health status  ...  We have known for a long time that arteries expand in order to absorb pressure; however, only recently have we identified that arteries also move longitudinally along the length of the arterial wall.  ...  ACKNOWLEDGEMENTS We would like to thank Daanish Mulla for his assistance with analysis, as well as the student volunteers who helped with data preparation for this study.  ... 
doi:10.1139/apnm-2017-0651 pmid:29171957 fatcat:gh7konomvfbblabeq72rac5izy

On the importance of the non-uniform aortic stiffening in the hemodynamics of physiological ageing

Stamatia Z Pagoulatou, Vasiliki Bikia, Bram Trachet, Theodore G. Papaioannou, Athanase D PROTOGEROU, Nikos Stergiopulos
2019 American Journal of Physiology. Heart and Circulatory Physiology  
Carotid-to-femoral pulse wave velocity (c-f PWV) was accurately predicted by the model (mean error=0.14 m/s, SD=0.77 m/s), with the greatest deviations being observed for older subjects.  ...  In regard to aortic pressure, model-derived systolic blood pressure and augmentation index were both in good agreement (mean difference of 2.3 mmHg and 4.25%, respectively) with the predictions of a widely  ...  wave velocity; CO, cardiac output; DBP, diastolic blood pressure; Table 2 . 2 Indices of correlation, accuracy, and agreement between the measured and method-derived c-f PWV values Correlation Pearson's  ... 
doi:10.1152/ajpheart.00193.2019 pmid:31538801 fatcat:xsndmkumpvhehh7glt4ydn333m

Pulmonary artery pulse pressure and wave reflection in chronic pulmonary thromboembolism and primary pulmonary hypertension

Vincent Castelain, Philippe Hervé, Yves Lecarpentier, Pierre Duroux, Gerald Simonneau, Denis Chemla
2001 Journal of the American College of Cardiology  
OBJECTIVES The purpose of this time-domain study was to compare pulmonary artery (PA) pulse pressure and wave reflection in chronic pulmonary thromboembolism (CPTE) and primary pulmonary hypertension (  ...  BACKGROUND Pulmonary artery pressure waveform analysis provides a simple and accurate estimation of right ventricular afterload in the time-domain.  ...  for the relatively lower pulse wave velocity (20, 27, 31) .  ... 
doi:10.1016/s0735-1097(00)01212-2 pmid:11263613 fatcat:gbggfe6ffvbzbijkz6r5lafx2a

AAPM/RSNA Physics Tutorial for Residents: Topics in US

Evan J. Boote
2003 Radiographics  
The continuing development of US equipment aims to provide a greater understanding of hemodynamics and the relationship between blood flow and various disease processes. ). 2 ‫.ء9‬ Vascular system, location  ...  The Doppler effect as developed by sound propagation in human tissues and with the velocities observed for the human vasculature produces shifts in the frequencies of returning echo signals.  ...  Pulsed-wave US spectrum displays the maximum, minimum, and average calculated blood flow velocities.  ... 
doi:10.1148/rg.235035080 pmid:12975518 fatcat:uzqm4faahvfctcm25gnpcctpjy
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