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Prototyping a genetics deductive database

C Hearne, Z Cui, S Parsons, S Hajnal
1994 Proceedings. International Conference on Intelligent Systems for Molecular Biology  
We are developing a laboratory notebook system known as the Genetics Deductive Database.  ...  The Genetics Deductive Database is built using new database technology which provides an object-oriented conceptual model, a declarative rule language, and a procedural update language.  ...  Acknowledgements This research was partly supported by the European Commission under ESPRIT Project 6333 IDEA (Intelligent Database Environments for Advanced Applications).  ... 
pmid:7584387 fatcat:zhlsegwikzcwhemdlse5zapwii

Using interval logic for order assembly

Z Cui
1994 Proceedings. International Conference on Intelligent Systems for Molecular Biology  
Then, we present and discuss a deductive and object-oriented data model based on this formalism for a genetic deductive database, and the inference rules required.  ...  The formalism supports the maintenance of coarser knowledge of unordered, partially ordered and completely ordered genetic data in a relational hierarchy.  ...  At the Imperial Cancer Research Fund, we are investigating how to build a genetics database in the context of deductive and object-oriented databases.  ... 
pmid:7584379 fatcat:arsaassavzfebcrhwopr6bowqa

Towards an information managemenet system for genomic objects and processes

Otto Ritter
1993 Genome Informatics Series  
The prototype system integrates public data of several major databases physically into a server readonly database.  ...  Integration of data and knowledge -deductive interface to the IGD database to faciliate logic based analysis of the data, and the representation of biological knowledge, as well as of data integrity rules  ... 
doi:10.11234/gi1990.4.456 fatcat:gw2d3kwevng3pfe4xld435rvhm

Molecular Epidemiology of Coxsackievirus A16: Intratype and Prevalent Intertype Recombination Identified

Xiangpeng Chen, Xiaojuan Tan, Jing Li, Yu Jin, Liming Gong, Mei Hong, Yonglin Shi, Shuangli Zhu, Baomin Zhang, Shuang Zhang, Yong Zhang, Naiying Mao (+2 others)
2013 PLoS ONE  
, 593 complete CVA16 VP1 sequences from 1981 to 2011, and prototype strains of human enterovirus species A (EV-A).  ...  To clarify the genetic characteristics and the epidemic patterns of CVA16 in mainland China, comprehensive bioinfomatics analyses were performed by using 35 CVA16 whole genome sequences from 1998 to 2011  ...  This deduction could also be supported by the nucleotide sequence identities with every prototype of EV-A.  ... 
doi:10.1371/journal.pone.0082861 pmid:24340064 pmcid:PMC3858299 fatcat:aca66jqlmne2vi2vaozvcpph4q

HYCONES: a hybrid connectionist expert system

B de F Leão, E B Reátegui
1993 Proceedings. Symposium on Computer Applications in Medical Care  
The paper describes the architecture of the system, focusing on the hybrid aspects of the knowledge base and on its automatic knowledge acquisition technique from a case database.  ...  This paper describes HYCONES, a tightly-coupled Hybrid Connectionist Expert System that integrates neural networks with a symbolic approach (frames).  ...  Deductive learning is achieved through the use of a technique similar to the recombination operator of genetic algorithms.  ... 
pmid:8130516 pmcid:PMC2248551 fatcat:3nwshyh2cbey5lqlj2gdtckz6q

Molecular Epidemiology of Echovirus 18 Circulating in Mainland China from 2015 to 2016

Xiangpeng Chen, Tianjiao Ji, Jiayun Guo, Wei Wang, Wenbo Xu, Zhengde Xie
2019 Virologica Sinica  
Combined with the sequences from the GenBank database, we performed an extensive genetic analysis.  ...  Echovirus 18 (E18), a serotype of Enterovirus B (EV-B) species, is an important pathogen in aseptic meningitis.  ...  Combined with the sequences from the GenBank database, we further performed an extensive genetic analysis to elucidate the molecular epidemiology and genetic characteristics of E18 in mainland China.  ... 
doi:10.1007/s12250-018-0080-8 pmid:30790201 pmcid:PMC6420525 fatcat:o5c3xzaguvhgvcveolnapuvxfi

GPR: A Data Mining Tool Using Genetic Programming

Balasubramaniam Ramesh
2001 Communications of the Association for Information Systems  
In Section III we discuss the application of genetic programming to data mining. Section IV provides a detailed description of GPR, our prototype data mining tool.  ...  We present a step-by-step method to implement GPR, and introduce a prototype that generates production rules from real life data.  ...  Deduction allows inference of specific knowledge about relationships between data elements in the database, much as a syllogism is constructed.  ... 
doi:10.17705/1cais.00506 fatcat:xbklzxyinjgtfj7ifchudm4j74

A semantic model for scholarly electronic publishing in Biomedical Sciences

Carlos H. Marcondes, Luciana R. Malheiros, Leonardo C. da Costa
2014 Semantic Web Journal  
The development and testing of a prototype of a Web submission interface to an electronic journal system that partially implements the proposed model are reported.  ...  A semantic model for scholarly electronic publishing is proposed, in which the article conclusion is specified by the author and recorded in a machine-understandable format, enabling semantic retrieval  ...  This paper reports the results of a partial implementation of the model as a prototype of a journal submission system.  ... 
doi:10.3233/sw-130111 fatcat:235ypjooibf5ld6dpvquh4mjni

Page 149 of Linguistics and Language Behavior Abstracts: LLBA Vol. 23, Issue 1 [page]

1989 Linguistics and Language Behavior Abstracts: LLBA  
A survey of relevant literature re- veals four explanations to this question: genetic, functional, probabilis- tic/statistical, & causal (deductive-nomological).  ...  A prototype model is used as the basis for discussion.  ... 

Optimization Models of Sound Systems Using Genetic Algorithms

Jinyun Ke, Mieko Ogura, William S.-Y. Wang
2003 Computational Linguistics  
In this study, optimization models using genetic algorithms (GAs) are proposed to study the configuration of vowels and tone systems.  ...  The GA model proposed for the study of tone systems uses a Pareto ranking method that is highly applicable for dealing with optimization problems having multiple criteria.  ...  The second author is also supported by a grant from the Ministry of Education, Science, Sports and Culture of Japan, no. 11610512. We thank C. C.  ... 
doi:10.1162/089120103321337412 fatcat:3ofraf6hjnf6zlthdie4ykjcqq

Hybridizing Differential Evolution With A Genetic Algorithm For Color Image Segmentation

R. V. V. Krishna, S. Srinivas Kumar
2016 Zenodo  
This paper proposes a hybrid of differential evolution and genetic algorithms to solve the color image segmentation problem.  ...  Clustering based color image segmentation algorithms segment an image by clustering the features of color and texture, thereby obtaining accurate prototype cluster centers.  ...  Extensive experimentation was conducted on images from Berkeley segmentation database.  ... 
doi:10.5281/zenodo.162592 fatcat:whliqlmobbdn3knmbftwi5xsdu

Alternative approach for learning and improving the MCDA method PROAFTN

Feras Al-Obeidat, Nabil Belacel
2011 International Journal of Intelligent Systems  
As a result, a massive amount of information is located in these databases; the knowledge within them is most likely important, but has yet to be identified or expressed.  ...  Introduction There are huge amounts of data being collected in databases every day.  ... 
doi:10.1002/int.20476 fatcat:rpm2e7easza2jiii6upxez3nni

AI integration for enhanced decision support

P.R. Watkins, T.W. Lin, D.E. O'Leary
1992 Proceedings of the Twenty-Fifth Hawaii International Conference on System Sciences  
This paper provides a perspective that is problem driven and suggests that AI integration is a matching process of problems/sub-problems with appropriate AI or other problem support technologies which  ...  As applied AI has matured and developed beyond Expert Systems to include Neural Nets, Genetic Algorithms, Model Based Systems, Fuzzy Logic, Natural Language and Case-based Reasoning, the need to provide  ...  Rather it is a how best situation. That is, how best can we solve or address a particular problem with the portfolio of AI and conventional DSS tools available.  ... 
doi:10.1109/hicss.1992.183473 fatcat:qlzehwylanb5nal4jzagsro7cq

Evaluation of human-readable annotation in biomolecular sequence databases with biological rule libraries

F. Eisenhaber, P. Bork
1999 Bioinformatics  
Motivation: Computer-based selection of entries from sequence databases with respect to a related functional description, e.g. with respect to a common cellular localization or contributing to the same  ...  Results: The prototype of a software system, the Meta_A(nnotator) program, is described and the results of its application to sequence attribute assignment and sequence selection problems, such as cellular  ...  The result of this deduction is called the primary attribute for the database entry.  ... 
doi:10.1093/bioinformatics/15.7.528 pmid:10487860 fatcat:yzaukvyf4beovgpled5qhod5vm

Application of knowledge base design techniques to genetic markers

Mark Graves
1995 Proceedings of the fourth international conference on Information and knowledge management - CIKM '95  
This process is supported by a knowledge base design tool, which we call WEAVE, that creates a prototype knowledge base when given a data model definition by a knowledge base developer.  ...  We show how our knowledge base design process can be used to develop a data model for genetic markers, which are biological constructs used to search for genes associated with genetic diseases.  ...  Graphs are also the foundation of a useful genetics database system.  ... 
doi:10.1145/221270.221624 dblp:conf/cikm/Graves95 fatcat:s2n6bgey3bgnfnzftojapg5dcu
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