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Design patterns for clinical guidelines

Mor Peleg, Samson W. Tu
2009 Artificial Intelligence in Medicine  
Methods and materials: We analyzed guidelines taken from the sub-domains of screening and immunization guidelines to find repeatable clinical abstractions and structured them as design templates to support  ...  Our goal was to support this step by providing computer-interpretable templates for representing guideline knowledge using clinical abstractions that are appropriate for particular guideline sub-domains  ...  Acknowledgments We would like to thank Prof. Perry Miller, Dr.  ... 
doi:10.1016/j.artmed.2009.05.004 pmid:19500956 fatcat:lpuaftoqqzcmzdli6hpgu5koge

Development of a computerised neurocognitive battery for children and adolescents with HIV in Botswana: study design and protocol for the Ntemoga study

J Cobb Scott, Amelia E Van Pelt, Allison M Port, Lucky Njokweni, Ruben C Gur, Tyler M Moore, Onkemetse Phoi, Ontibile Tshume, Mogomotsi Matshaba, Kosha Ruparel, Jennifer Chapman, Elizabeth D Lowenthal
2020 BMJ Open  
Here, we present a protocol to culturally adapt and validate the Penn Computerized Neurocognitive Battery (PennCNB) and examine its validity for detecting both advanced and subtle neurodevelopmental problems  ...  We aim to validate the PennCNB in this setting by culturally adapting and then administering the adapted version of the battery to 200 HIV-infected, 200 HIV-exposed uninfected and 240 HIV-unexposed uninfected  ...  Acknowledgements The authors wish to thank our Stakeholder Group in Botswana who provided invaluable guidance and support for this project. Funding This work was supported by the NIH (R01 HD095278).  ... 
doi:10.1136/bmjopen-2020-041099 pmid:32847928 fatcat:fqotuxwchnexhcmwlkh3ni7qpu

Designing an Intervention and Plan its Evaluation - Development of a protocol of a randomised feasibility study for a onent intervention to improve instrumental activities of daily living in persons with mild cognitive impairment

Bruderer,-Hofstetter, Marina, Gerold Stucki, Karin Niedermann, Thomas Münzer
2021 Zenodo  
Aims The objective of this doctoral thesis was to develop a study protocol of a randomised feasibility study for a multi-component intervention targeting IADL functioning in persons with MCI.  ...  Based on a systematic review, including Bayesian network meta-analyses, the evidence from randomised controlled trials on the effects of multi-component interventions on IADL performance, cognitive function  ...  Acknowledgements The authors would like to thank all the participants and their informants for their participation in this study. The authors are also grateful to Dr.  ... 
doi:10.5281/zenodo.4561808 fatcat:km3hgfwz45e6zm4tx4xncvy33m

Architectural Software Patterns for the Development of IoT Smart Applications [article]

Fabrizio Borelli and Gabriela Biondi and Flávio Horita and Carlos Kamienski
2020 arXiv   pre-print
Three smart applications for cities, buildings, and agriculture were selected as examples of using some components, connectors, and well-known design patterns.  ...  However, architectural solutions are presented with no rationale for the choice of software components and the way they relate to each other.  ...  Acknowledgment The authors would like to thank to SWAMP Project.  ... 
arXiv:2003.04781v2 fatcat:zlyi6e2wwvetpm7a3iifozugoe

e-Science, caGrid, and Translational Biomedical Research

J. Saltz, T. Kurc, S. Hastings, S. Langella, S. Oster, D. Ervin, A. Sharma, T. Pan, M. Gurcan, J. Permar, R. Ferreira, P. Payne (+7 others)
2008 Computer  
Diverse data, complex execution environments, and demanding security and reliability requirements make the implementation of these projects extremely challenging and require novel e-Science technologies  ...  Tahsin Kurc[Senior researcher and chief software architect], Tony Pan[Senior research specialist], Abstract Translational research projects target a wide variety of diseases, test many different kinds  ...  Acknowledgments We thank Laura Esserman and Nola Hylton at the University of California, San Francisco, the PIs for the I-SPY trial project; Howard Fine at the NCI, the PI for the GMDI and Rembrandt projects  ... 
doi:10.1109/mc.2008.459 pmid:21311723 pmcid:PMC3035203 fatcat:aqwbedm2kveejallfldacjrpbe

EON: A Component-Based Approach to Automation of Protocol-Directed Therapy

Mark A. Musen, Samson W. Tu, Amar K. Das, Yuval Shahar
1996 JAMIA Journal of the American Medical Informatics Association  
P rovision of, automated support for planning protocol-directed therapy requires a computer program to take as input clinical data stored in an electronic patient-record system and to generate as output  ...  This paper presents a synthesis of research Affiliation of the authors:  ...  of clinical protocols demonstrates that protocol authors often specify complex patterns of clinical events that dictate particular clinical actions that providers should follow.'  ... 
doi:10.1136/jamia.1996.97084511 pmid:8930854 pmcid:PMC116322 fatcat:5wg3bz5nunezjlgjvya55yeely

Formal representation of eligibility criteria: A literature review

Chunhua Weng, Samson W. Tu, Ida Sim, Rachel Richesson
2010 Journal of Biomedical Informatics  
Standards-based, computable knowledge representations for eligibility criteria are increasingly needed to provide computer-based decision support for automated research participant screening, clinical  ...  We surveyed the literature and identified five aspects of eligibility criteria knowledge representation that contribute to the various research and clinical applications: the intended use of computable  ...  Its contents are solely the responsibility of the authors and do not necessarily represent the official view of NIH.  ... 
doi:10.1016/j.jbi.2009.12.004 pmid:20034594 pmcid:PMC2878905 fatcat:md7wxjhavfaghjnglyuqdqxwae

Associations of Objectively-Measured Sedentary Time and Patterns with Cognitive Function in Non-Demented Japanese Older Adults: A Cross-Sectional Study

Sanmei Chen, Tao Chen, Takanori Honda, Yu Nofuji, Hiro Kishimoto, Kenji Narazaki
2022 International Journal of Environmental Research and Public Health  
This study aimed to investigate the cross-sectional associations of objectively-measured sedentary time and patterns with cognitive function in Japanese older adults.  ...  Our results encourage further researches to confirm the role of prolonged sedentary time in changes to cognitive domains over time among older adults.  ...  Conflicts of Interest: The authors declare no conflict of interest.  ... 
doi:10.3390/ijerph19041999 pmid:35206188 pmcid:PMC8871939 fatcat:h6uiqs535fhjlo7pgluvzw7dzq

Predictive Modelling of The Dynamic Patterns of Thinking in Attention-Deficit/Hyperactivity Disorder: Diagnostic Accuracy of Spatiotemporal Fractal Measures [article]

F. Labra-Spröhnle, G. Smith, H. Ahammer, C. Postlethwaite, I. Liu, P. Teesdale-Spittle, M. Frean
2018 bioRxiv   pre-print
The index test consisted of a computer-based inference task with a set of eight different instances of the "Battleships" game to be solved.  ...  paradigm, we performed a prospective diagnostic accuracy trial to assess the diagnostic value of several fractal measures from the thinking processes or inferences in a cohort of ADHD children and typically  ...  board for supporting this clinical trial.  ... 
doi:10.1101/420513 fatcat:zy6lxqbudbc2bmgtw236bcubii

Dynamic handwriting analysis for the assessment of neurodegenerative diseases: a pattern recognition perspective

Donato Impedovo, Giuseppe Pirlo
2018 IEEE Reviews in Biomedical Engineering  
This paper addresses the most relevant results obtained in the field of online (dynamic) analysis of handwritten trials by AD and PD patients.  ...  The survey is made from a pattern recognition point of view, so that different phases are described. Data acquisition deals not only with the device, but also with the handwriting task.  ...  ACKNOWLEDGMENT The authors would like to thank Dr. L. Rudd for proofreading the paper.  ... 
doi:10.1109/rbme.2018.2840679 pmid:29993722 fatcat:dn2tihpfxbemlfm35bdbtqi544

Industry–Academia Research Collaboration and Knowledge Co-creation: Patterns and Anti-patterns

Dusica Marijan, Sagar Sen
2022 ACM Transactions on Software Engineering and Methodology  
Drawing upon the findings made and the experience gained, we provide a set of 14 patterns and 14 anti-patterns for industry–academia collaborations, aimed to support other researchers and practitioners  ...  This article reports on the experience of research collaboration and knowledge co-creation between industry and academia in software engineering as a way to bridge the research–practice collaboration gap  ...  In SE, they are often used in the context of design patterns [16] .  ... 
doi:10.1145/3494519 fatcat:b5capq3ybncapddvn5rnec5ayu

The ACGT project in retrospect: Lessons learned and future outlook

Anca Bucur, Stefan Ruping, Thierry Sengstag, Stelios Sfakianakis, Manolis Tsiknakis, Dennis Wegener
2011 Procedia Computer Science  
In this paper we describe the way the ACGT consortium has approached important challenges in the design and the execution of the clinical trials such as the issues of data integration, semantics based  ...  and services in support of multicentric, post-genomic clinical trials.  ...  Acknowledgements The authors gratefully acknowledge the financial support of the European Commission for the Project ACGT, FP6/2004/IST-026996.  ... 
doi:10.1016/j.procs.2011.04.119 fatcat:ls5emmpmrrfwnhnkscbpazorge

Brain neural activity patterns yielding numbers are operators, not representations

Walter J. Freeman, Robert Kozma
2009 Behavioral and Brain Sciences  
Abstract: The study of neuronal specialisation in different cognitive and perceptual domains is important for our understanding of the human brain, its typical and atypical development, and the evolutionary  ...  Central to this understanding is the issue of numerical representation, and the question of whether numbers are represented in an abstract fashion.  ...  How are we to relate the authors' arguments with other, presumably supra-modal conceptual domains?  ... 
doi:10.1017/s0140525x09990057 fatcat:b647jvvmcjesdftv5ll35gc2xy

Patterns of Index Biologic Drug Registrations To A Pharmacovigilance Register of Psoriasis Patients

KJ Mason, I Evans, K McElhone, M Lunt, S Hussain, B Kirby, A Burden, NJ Reynolds, CE Griffiths
2016 Value in Health  
ISPOR's global reach is critically important and positions us to have a positive impact on health globallyand not just by sheer numbers but by the quality of our science.  ...  Additional information on ISPOR and membership benefits can found at www.ispor.org. 3 Dear Colleagues, Welcome to Vienna and ISPOR's 19th Annual European Congress, the largest international gathering of  ...  Following the presentation, the audience will be encouraged to discuss the pros and cons of these methods compared to currently used approaches in the design and analysis of oncology clinical trials.  ... 
doi:10.1016/j.jval.2016.09.1309 fatcat:fvh7blkvqngjrau3j6iid6cwpm

A highly scalable, interoperable clinical decision support service

Howard S Goldberg, Marilyn D Paterno, Beatriz H Rocha, Molly Schaeffer, Adam Wright, Jessica L Erickson, Blackford Middleton
2014 JAMIA Journal of the American Medical Informatics Association  
to provide consistent, maintainable, and scalable decision support in a variety of settings.  ...  Objective To create a clinical decision support (CDS) system that is shareable across healthcare delivery systems and settings over large geographic regions.  ...  Acknowledgements The authors would like to thank the members of the PHS ECRS team, for their effort on and support of this project: Deepika Pabbathi, Richard Boyer, Eugene Shilmayster, and Michael Vashevko  ... 
doi:10.1136/amiajnl-2013-001990 pmid:23828174 pmcid:PMC3957399 fatcat:4ziy7jrwbnffdivuc2jyyen4oq
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