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Principle Angle Enrichment Analysis (PAEA): Dimensionally reduced multivariate gene set enrichment analysis tool

Neil R. Clark, Maciej Szymkiewicz, Zichen Wang, Caroline D. Monteiro, Matthew R. Jones, Avi Ma'ayan
2015 2015 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)  
PAEA employs dimensionality reduction and a multivariate approach for gene set enrichment analysis.  ...  As reported, this approach has a natural extension to gene set analysis which we call Principal Angle Enrichment Analysis (PAEA).  ...  Conclusion Here we present the first benchmarking results for Principal Anlge Enrichment Analysis method, a dimensionality reduced multivariate approach to gene set enrichment.  ... 
doi:10.1109/bibm.2015.7359689 pmid:26848405 pmcid:PMC4737646 dblp:conf/bibm/ClarkSWMJM15 fatcat:73bu3lcxdvhsfhpdrdfr3lfhta