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Prefrontal cortical abnormalities in currently depressed versus currently remitted patients with major depressive disorder
2011
NeuroImage
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Previous neuromorphometric investigations of major depressive disorder (MDD) have reported abnormalities in gray matter in several regions, although the results have been inconsistent across studies. ...
The aim of the present study was to investigate gray matter (GM) differences in unmedicated, currently-depressed participants (dMDD) and unmedicated, currently-remitted (rMDD) participants with MDD compared ...
Regions where gray matter density was reduced in currently depressed (N=58) subjects with major depressive disorder compared to healthy controls (N=107) (a) and to currently remitted MDD subjects (N=27 ...
doi:10.1016/j.neuroimage.2010.11.011
pmid:21073959
pmcid:PMC3020249
fatcat:cxfsm7ypzbdt7lou7xenq3af4y
Neuroimaging in bipolar disorder: A critical review of current findings
2007
Current Psychiatry Reports
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Also, the depression associated with bipolar disorder frequently continues to be treated as unipolar depression (UPD). ...
These abnormalities in core domains represent potential endophenotypes of the illness. ...
Emotion processing In remitted and depressed patients with bipolar disorder, decreased blood flow was shown in medial prefrontal cortex during sad mood induction relative to baseline [35] , with lateral ...
doi:10.1007/s11920-007-0070-2
pmid:18221633
pmcid:PMC2686113
fatcat:jk3cwnpm2nhmfbwgt53jmqwxyy
Amygdala activity and prefrontal cortex-amygdala effective connectivity to emerging emotional faces distinguish remitted and depressed mood states in bipolar disorder
2012
Bipolar Disorders
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Methods-Thirty-one remitted adults with BD [(remitted BD), mean age = 32 years], 21 adults with BD in a depressed episode [(depressed BD), mean age = 33 years], and 25 healthy control participants [(HC ...
Results-Our findings indicated patterns of abnormally elevated bilateral amygdala activity in response to emerging fearful, sad, and angry facial expressions in remitted-BD subjects versus HC, and abnormally ...
Second, our previous FC data in individuals with remitted and depressed BD (12) allowed us to hypothesize that remitted-BD and depressed-BD patients versus HC would both show abnormal right-sided amydgala-prefrontal ...
doi:10.1111/j.1399-5618.2012.00999.x
pmid:22420592
pmcid:PMC3703524
fatcat:qzjrhm2ujbgsnh6h3tt54ku2tu
Distinguishing between Unipolar Depression and Bipolar Depression: Current and Future Clinical and Neuroimaging Perspectives
2013
Biological Psychiatry
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Differentiating bipolar disorder (BD) from recurrent unipolar depression (UD) is a major clinical challenge. ...
, and differential patterns of functional abnormalities in emotion regulation and attentional control neural circuitry in the two depression types. ...
Subcortical and ventral prefrontal cortical neural responses to facial expressions distinguish patients with bipolar disorder and major depression. Biol Psychiatry. 2004; 55:578-587. ...
doi:10.1016/j.biopsych.2012.06.010
pmid:22784485
pmcid:PMC3494754
fatcat:iipn3ugegbaw3jq7qk4l2j6hxi
Self-Referential Processing, Rumination, and Cortical Midline Structures in Major Depression
2013
Frontiers in Human Neuroscience
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Self-referential processing in major depression seems associated with abnormally increased activity of the anterior cortical midline structures. ...
The role of the medial prefrontal cortex in self-referential processing has been previously emphasized in acute major depression. ...
portion in particular, in the pathophysiology of major depressive disorder. ...
doi:10.3389/fnhum.2013.00666
pmid:24124416
pmcid:PMC3794427
fatcat:p7zj552t55a5jm2x6sggmmktga
Structural brain networks in remitted psychotic depression
2020
Neuropsychopharmacology
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Major depressive disorder with psychotic features (psychotic depression) is a severe disorder. ...
Overall, decreased cortical thickness was found in five structural brain networks in patients with remitted psychotic depression and brain-behavior relationships were observed, particularly between the ...
INTRODUCTION Major depressive disorder (MDD) with psychotic features (psychotic depression) is a severe disorder with a lifetime prevalence of 0.35-1% [1] . ...
doi:10.1038/s41386-020-0646-7
pmid:32109935
fatcat:isf5mifztjd6pabvzcxnaafvtq
Bruijniks_Supplemental_materials_2 – Supplemental material for The Potential Role of Learning Capacity in Cognitive Behavior Therapy for Depression: A Systematic Review of the Evidence and Future Directions for Improving Therapeutic Learning
2019
Figshare
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Supplemental material, Bruijniks_Supplemental_materials_2 for The Potential Role of Learning Capacity in Cognitive Behavior Therapy for Depression: A Systematic Review of the Evidence and Future Directions ...
Huibers in Clinical Psychological Science ...
III
Ruchsow et al.,
2004
Case-control
16 patients with DSM-IV
major depressive disorder
in remission and 16
matched controls
Current and previous
CBT treatment
unknown. ...
doi:10.25384/sage.7901714
fatcat:btd2nlxygvertbbx43j5skvace
Abnormally increased effective connectivity between parahippocampal gyrus and ventromedial prefrontal regions during emotion labeling in bipolar disorder
2009
Psychiatry Research : Neuroimaging
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Forty-six individuals (age range: 18-56 years); 21 with a DSM-IV diagnosis of BD, type I currently remitted; 25 age-and gender-matched healthy controls (HC). ...
Emotional liability and mood dysregulation characterize bipolar disorder (BD), yet no study has examined effective connectivity between parahippocampal gyrus and prefrontal cortical regions in ventromedial ...
The research in this study was supported in part by a NARSAD Independent Investigator Award to MLP and 5R01 MH076971-01. MLP is the NARSAD Nellie Blumenthal Investigator. ...
doi:10.1016/j.pscychresns.2009.04.015
pmid:19910166
pmcid:PMC2787954
fatcat:2n7ftt45vja5hpk6ookvrxkcnm
State and trait influences on mood regulation in bipolar disorder: blood flow differences with an acute mood challenge
2003
Biological Psychiatry
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Even in remission, patients with bipolar disorder (BD) remain sensitive to external stressors that can trigger new episodes. ...
Unique to remitted subjects with BD were rCBF increases in dorsal anterior cingulate and in premotor cortex. Lateral prefrontal rCBF decreases were unique to depressed subjects with BD. ...
We thank the Bipolar and Depression Clinics Staff at the Centre for Addiction and Mental Health, Clarke Site, for their support. ...
doi:10.1016/s0006-3223(03)00691-7
pmid:14643095
fatcat:wbgdc3wghne4fazfed6tsag4bu
A functional anatomical study of unipolar depression
1992
Journal of Neuroscience
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Amaral DC, Price JL (1984) Amygdalocortical projections in the monkey. ...
References Aggleton JP, Passingham RE (198 1) Syndrome produced by lesions of the amygdala in monkeys (Mucucu muluttu). J Comp Physiol Psychol 95~961-977. ...
demarcated a prefrontal cortical abnormality in unipolar depression. ...
doi:10.1523/jneurosci.12-09-03628.1992
pmid:1527602
fatcat:c4alismv6bfmthocttvlvgzhge
Neural circuits underlying the pathophysiology of mood disorders
2012
Trends in Cognitive Sciences
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, physiology, and neurochemistry in human subjects with mood disorders have enabled significant advances towards elucidating the pathophysiology of major depressive disorder (MDD) and bipolar disorder ...
Animal and human studies of mood disorders Major depressive disorder (MDD) and bipolar disorder (BD) constitute the first and fifth leading causes of years lived with disability, respectively [1]. ...
patients before versus after treatment and from remitted patients scanned before versus during depressive relapse [56, 57] . ...
doi:10.1016/j.tics.2011.12.011
pmid:22197477
fatcat:btjyfiyfyrbq3plck75rgnkzwu
Bruijniks_Supplemental_Material – Supplemental material for The Potential Role of Learning Capacity in Cognitive Behavior Therapy for Depression: A Systematic Review of the Evidence and Future Directions for Improving Therapeutic Learning
2019
Figshare
Preserved Fulltext
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The file type is application/pdf.
Supplemental material, Bruijniks_Supplemental_Material for The Potential Role of Learning Capacity in Cognitive Behavior Therapy for Depression: A Systematic Review of the Evidence and Future Directions ...
Huibers in Clinical Psychological Science ...
III
Ruchsow et al.,
2004
Case-control
16 patients with DSM-IV
major depressive disorder
in remission and 16
matched controls
Current and previous
CBT treatment
unknown. ...
doi:10.25384/sage.7901711.v2
fatcat:vequel76uvev3hb5oasp52oxme
Bruijniks_Supplemental_Material – Supplemental material for The Potential Role of Learning Capacity in Cognitive Behavior Therapy for Depression: A Systematic Review of the Evidence and Future Directions for Improving Therapeutic Learning
2019
Figshare
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is application/pdf.
Supplemental material, Bruijniks_Supplemental_Material for The Potential Role of Learning Capacity in Cognitive Behavior Therapy for Depression: A Systematic Review of the Evidence and Future Directions ...
Huibers in Clinical Psychological Science ...
III
Ruchsow et al.,
2004
Case-control
16 patients with DSM-IV
major depressive disorder
in remission and 16
matched controls
Current and previous
CBT treatment
unknown. ...
doi:10.25384/sage.7901711.v1
fatcat:cpjge2qierfj7izgezz2vdfrsm
Abnormal prefrontal activity subserving attentional control of emotion in remitted depressed patients during a working memory task with emotional distracters
2011
Psychological Medicine
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Patients with major depressive disorder (MDD) show deficits in processing of facial emotions that persist beyond recovery and cessation of treatment. ...
Abnormalities in neural areas supporting attentional control and emotion processing in remitted depressed (rMDD) patients suggests that there may be enduring, trait-like abnormalities in key neural circuits ...
Acknowledgments We thank all of the patients who participated in this study, R. ...
doi:10.1017/s0033291711001097
pmid:21733287
fatcat:7hkav63tcba4flv5vv2kstgzcu
Reduced volume of orbitofrontal cortex in major depression
2002
Biological Psychiatry
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The purpose of this study was to measure volume of orbitofrontal cortex and other frontal cortical subregions in patients with major depression. ...
Methods: Magnetic resonance imaging was used to measure volume of the orbitofrontal cortex and other frontal cortical regions in patients with major depression in remission (n ϭ 15) and comparison subjects ...
The authors thank Kathy Colonese, Jacque Piscitelli, and Lisa Roach for assistance in patient assessments and data management; Hedy Sarofin for expert assistance in MRI acquisition; and Helen Sayward for ...
doi:10.1016/s0006-3223(01)01336-1
pmid:11958777
fatcat:yiagm57b5zb2ndnryulr6jym7u
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