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Predicting the location of entorhinal cortex from MRI
2009
NeuroImage
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to quantify the variability of EC with respect to cortical geometry, and made predictions of its location on in vivo scans. ...
Entorhinal cortex (EC) is a medial temporal lobe area critical to memory formation and spatial navigation that is among the earliest parts of the brain affected by Alzheimer's disease (AD). ...
One of the authors (LLW) has obtained consulting income from Siemens Healthcare. ...
doi:10.1016/j.neuroimage.2009.04.033
pmid:19376238
pmcid:PMC2738987
fatcat:idjzay6c2faw7jwxecylko3wju
Predicting the location of human perirhinal cortex, Brodmann's area 35, from MRI
2013
NeuroImage
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Augustinack). 1 Data used in preparation of this article were obtained from the Alzheimer's Disease Neuroimaging Initiative (ADNI) database (adni.loni.ucla.edu). ...
To test the accuracy of the probabilistic mapping, we measured the Hausdorff distance between the predicted and true labels and found that the median Hausdorff distance was 4.0 mm for the left hemispheres ...
Imaging and Bioengineering (R01EB006758), the National Institute on Aging (AG022381) and (AG028521), the Massachusetts ...
doi:10.1016/j.neuroimage.2012.08.071
pmid:22960087
pmcid:PMC3508349
fatcat:dchqae66lfcqzf3usxnianl64q
Hippocampal Volume and Entorhinal Cortex Thickness in Alzheimer's Disease
2022
Indian Journal of Forensic Medicine & Toxicology
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This study aims to determine hippocampal volume and entorhinal cortex thickness in Alzheimer's disease obtained from a group of patients who underwent head MRI. ...
The mean thickness of right, left, and total entorhinal cortex was 1.821±0.459 mm; 1.463±0.369 mm; and 3.285±0.791 mm, respectively. ...
Acknowledgement We would like to thank Department of Radiology of Dr. Soetomo Hospital Surabaya, Indonesia in providing the data for analysing. ...
doi:10.37506/ijfmt.v16i1.17577
fatcat:mhpwgabxtfbkxfcjly4acjwzfu
Navigating the future of clinical assessments
2019
Brain
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This scientific commentary refers to 'Differentiation of mild cognitive impairment using an entorhinal cortex-based test of virtual reality navigation' by Howett et al. ( ...
Located in the medial temporal lobe, the entorhinal cortex (EC) is particularly vulnerable to accumulation of tau neurofibrillary tangles early in Alzheimer's disease. ...
To examine the neural correlates of successful path integration, Howett et al. segmented structural MRI scans to assess the relationship between the integrity of different brain regions (including entorhinal ...
doi:10.1093/brain/awz121
pmid:31135046
fatcat:ph2p6mrjobemzh63bt7qdavsxe
MRI hippocampal and entorhinal cortex mapping in predicting conversion to Alzheimer's disease
2012
NeuroImage
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Objective-Using MRI surface morphometry mapping, to evaluate local deformations of the hippocampus, parahippocampal gyrus, and entorhinal cortex in predicting conversion from mild cognitive impairment ...
Methods-Baseline brain MRI with surface morphological analysis was performed in 130 outpatients with MCI, broadly defined, and 61 healthy controls followed for an average of 4 years in a single site study ...
Acknowledgments Supported in part by grants AG17761 and P30 AG08051 from the National Institute of Aging. ...
doi:10.1016/j.neuroimage.2012.01.075
pmid:22289801
pmcid:PMC3320768
fatcat:kamwgivw5nbhbafaj7rxa5kghe
Basal forebrain volume reliably predicts the cortical spread of Alzheimer's degeneration
2020
Brain
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By contrast, smaller baseline entorhinal volumes predicted degeneration in the medial temporal cortex, recapitulating a prior influential staging model. ...
cortex. ...
and the Canada First Research Excellence Fund (T.W.S. and R.N.S.). S.F.C was supported by the Doctoral College "Imaging the Mind" (FWF-W1233) of the Austrian Science Fund. ...
doi:10.1093/brain/awaa012
pmid:32203580
pmcid:PMC7092749
fatcat:tcx4jdr3bbgv7ol45rsysypxoy
Brain imaging evidence of preclinical Alzheimer's disease in normal aging
2006
Annals of Neurology
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The anatomical location of these findings suggests detection of preclinical Alzheimer's disease pathology. ...
Both hippocampal (p ؍ 0.03) and entorhinal cortical volumes (p ؍ 0.01) predicted decline on delayed recall over time, and entorhinal cortical volumes remained significant when converters were excluded ...
or hippocampus is the most sensitive location for the detection of early disease with MRI. 35, 36 However, the entorhinal cortex pathologically is the site that is affected earliest by neurofibrillary ...
doi:10.1002/ana.20799
pmid:16470518
fatcat:dhzhjehga5dvjeozg753kut3sq
MRI Overestimates Excitotoxic Amygdala Lesion Damage in Rhesus Monkeys
2017
Frontiers in Integrative Neuroscience
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For unintended damage, MRI estimates correlated with histological assessment for entorhinal cortex, perirhinal cortex and hippocampus, though MRI significantly overestimated the extent of that damage in ...
The field will benefit from more research into in vivo lesion assessment techniques, and additional evaluation of the accuracy of MRI assessment in different brain areas. ...
This work was supported by the Intramural Research Program of the National Institute of Mental Health (NIMH; ZIAMH0 02887). ...
doi:10.3389/fnint.2017.00012
pmid:28642691
pmcid:PMC5462941
fatcat:2nm4aoqmznb2rgvwqlxahcttha
MRI parcellation of ex vivo medial temporal lobe
2014
NeuroImage
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We have identified several cytoarchitectonic features in the medial temporal lobe with high resolution ex vivo MRI, including gray matter structures such as the entorhinal layer II 'islands', perirhinal ...
Localization of Brodmann areas 28 and 35 (entorhinal and perirhinal, respectively) demonstrates MRI based area boundaries validated with multiple methods and histological stains. ...
Conflict of interest The authors have no conflict of interest to disclose regarding this work. ...
doi:10.1016/j.neuroimage.2013.05.053
pmid:23702414
pmcid:PMC3883990
fatcat:gtzhycjnzrgfdmioukf6ok646y
Medial temporal cortices in ex vivo magnetic resonance imaging
2013
Journal of Comparative Neurology
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This review focuses on the ex vivo magnetic resonance imaging (MRI) modeling of medial temporal cortices and associated structures, the entorhinal verrucae and the perforant pathway. ...
Neural information from multiple modalities converge in the entorhinal cortex and then project to the hippocampus via the perforant pathway (Van Hoesen et al., 1972; Van Hoesen and Pandya, 1975a,b). ...
Acknowledgments The authors thank those who generously donated the brain and made this research possible. ...
doi:10.1002/cne.23432
pmid:23881818
pmcid:PMC6014627
fatcat:tq263igezfbr5ks2zqjwzjrdpa
Detection of entorhinal layer II using Tesla magnetic resonance imaging
2005
Annals of Neurology
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The entorhinal cortex receives vast sensory association input, and its major output arises from the layer II and III neurons that form the perforant pathway. ...
In 70 and 100m isotropic data, the entorhinal islands were clearly visible throughout the anterior-posterior extent of entorhinal cortex. ...
Fig 2 . 2 Corresponding high-resolution magnetic resonance image (MRI) and histological Nissl section of the entorhinal cortex. ...
doi:10.1002/ana.20426
pmid:15786476
pmcid:PMC3857582
fatcat:adzmrgvl5jbhdgokfwdfmznose
MRI based volumetric analysis of entorhinal cortex in elderly subjects with mild cognitive impairment and in subjects with normal cognition to see effects of aging on volume of ERC
2020
International Journal of Research in Medical Sciences
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Aim of the study was to evaluate the volume of entorhinal cortex in patients of MCI and to compared the volume with patients of normal cognition. ...
Volume of entorhinal cortex was measured on 1 mm thick T1 coronal oblique MR scans by manually tracing the boundaries defined by two widely used methods i.e. ...
. 16 Changes in the ERC in elderly individuals seemed to be predictive of the transition from normal cognition to MCI. 17 The volume of the entorhinal cortex differentiated the subjects from those ...
doi:10.18203/2320-6012.ijrms20202884
fatcat:fs2yvuwygrg3pd2k4ja4zxlt5q
Hippocampal disconnection contributes to memory dysfunction in individuals at risk for Alzheimer's disease
2006
Proceedings of the National Academy of Sciences of the United States of America
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Table 2 shows the Talairach coordinates (29) and cluster size for all statistically significant areas in white ...
Entorhinal Cortex and Hippocampal Volumes. Predicting Memory Performance from MRI Measures. ...
from the entorhinal cortex. ...
doi:10.1073/pnas.0603414103
pmid:16785436
pmcid:PMC1479867
fatcat:ih3agsjpdvbpfp4umacc5ah2na
Use of structural magnetic resonance imaging to predict who will get Alzheimer's disease
2000
Annals of Neurology
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Baseline MRI measures of the entorhinal cortex, the banks of the superior temporal sulcus, and the anterior cingulate were most useful in discriminating the status of the subjects on follow-up examination ...
One hundred percent (100%) of normal subjects and patients with mild AD could be discriminated from one another based on these MRI measures. ...
This study was supported by the National Institutes of Health (grants P01-AG04953, P01-CA67165, R01-AG08487, and P50-AG05236, and contract N01-NS-0-2397). ...
doi:10.1002/1531-8249(200004)47:4<430::aid-ana5>3.0.co;2-i
pmid:10762153
fatcat:mx3quuqel5fkrdigyfdnbyfxum
Use of structural magnetic resonance imaging to predict who will get Alzheimer's disease
2000
Annals of Neurology
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Baseline MRI measures of the entorhinal cortex, the banks of the superior temporal sulcus, and the anterior cingulate were most useful in discriminating the status of the subjects on follow-up examination ...
One hundred percent (100%) of normal subjects and patients with mild AD could be discriminated from one another based on these MRI measures. ...
This study was supported by the National Institutes of Health (grants P01-AG04953, P01-CA67165, R01-AG08487, and P50-AG05236, and contract N01-NS-0-2397). ...
doi:10.1002/1531-8249(200004)47:4<430::aid-ana5>3.3.co;2-9
pmid:10762153
fatcat:ux7uuw25w5gklhrcxs2dwafoz4
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