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Omouma: a prospective mother and child cohort aiming to identify early biomarkers of pregnancy complications in women living in Qatar

Manoj Kumar, Marwa Saadaoui, Duaa Ahmed Elhag, Selvasankar Murugesan, Shaikha Al Abduljabbar, Yassin Fagier, Osman Ortashi, Hala Abdullahi, Ibrahim Ibrahim, Medhat Alberry, Anthony Abbas, Sawssan R. Ahmed (+4 others)
2021 BMC Pregnancy and Childbirth  
The objective of the present protocol is to build a longitudinal mother-baby cohort and use multi-omics technologies to help identify predictive biomarkers of adverse pregnancy outcomes, early life determinants  ...  Discussion It is expected that the present study will provide valuable insights into predicting pregnancy complications and neonatal health outcomes.  ...  Acknowledgements We would like to express our gratitude to the cohort participants and the continuous support of Gynecology, Obstetrics and Maternal Fetal Medicine departments at Sidra Medicine.  ... 
doi:10.1186/s12884-021-04029-4 pmid:34412611 pmcid:PMC8377974 fatcat:eykt6bb5n5g3taof2ryivx7lxa

Abstracts from the XIth World DOHaD Congress

2019 Journal of Developmental Origins of Health and Disease  
However, the association between preconception body mass index(BMI) or fasting plasma glucose(FPG) level as well as the combined effect and PTB risk were not well investigated.  ...  The aim of this study is to analyze the impact of maternal diabetes over placental steroidogenesis and ovarian function and metabolic profile of female newborns at the time of birth (TOB).  ...  Models were estimated via cross-validated, ensemble machine learning (e.g. Bayes GLM, neural net).  ... 
doi:10.1017/s2040174419000643 fatcat:sgbbtoqodrhipjzyc33ujpt5gq

Imaging Developmental and Interventional Plasticity Following Perinatal Stroke

Brandon T Craig, Alicia Hilderley, Adam Kirton, Helen L Carlson
2020 Canadian Journal of Neurological Sciences  
Perinatal stroke occurs around the time of birth and leads to lifelong neurological disabilities including hemiparetic cerebral palsy.  ...  Such techniques can also be used to investigate how the brain responds to treatment (interventional neuroplasticity).  ...  This is required to identify individual factors that predict responsiveness to generate personalized neurorehabilitation to optimize function.  ... 
doi:10.1017/cjn.2020.166 pmid:32727626 fatcat:o4inwbmxdzgidfq4pjkjpq4joq

The Definition and Classification of Cerebral Palsy

2007 Developmental Medicine & Child Neurology  
It illustrates the difficulties inherent in trying to agree what we mean by the terms we use and that a classification that suits one purpose, such as a diagnostic approach, may not always be ideal for  ...  It is followed by a section summarizing most of the presentations at the workshop in Bethesda in 2004 which provided the background to the present Report.  ...  Acknowledgements The author is grateful to Peter Rosenbaum, Jennifer Kurinczuk, and Ray Fitzpatrick, and also the anonymous peer reviewer, for their comments on previous versions of the manuscript.  ... 
doi:10.1111/j.1469-8749.2007.00001.x pmid:17371509 fatcat:dkqbrjurrnc3bejj2w53rqehmq

Matter Mind Matter [article]

Tom Birkoben, Hermann Kohlstedt
2022 arXiv   pre-print
The dual importance of local learning rules is addressed, from spike timing dependent plasticity at the neuron level to the interwoven morphological and dynamical mechanisms of the global network.  ...  While in machine learning system training is performed on virgin networks without any a priori knowledge, the approach proposed here distinguishes itself unambiguously by employing growth mechanisms as  ...  Moreover, the financial support by the DFG via the Research Unit 2093: "Memristive Devices for neural Systems" is acknowledged.  ... 
arXiv:2204.12774v1 fatcat:gm2z4ykduvcpxjdujx55g5qvxe

The signal functions of early infant crying

Joseph Soltis
2004 Behavioral and Brain Sciences  
Current evidence does not strongly support any one of these hypotheses, but the evidence is most consistent with the hypothesis that excessive early infant crying is a signal of vigor that evolved to reduce  ...  Although there is not strong evidence for acoustically distinct cry types, infant cries may function as a graded signal.  ...  ACKNOWLEDGMENTS We are indebted to Sandra Elincx for coming up with the idea of scanning subjects while they listened to infant cries.  ... 
pmid:15773426 fatcat:76miol3uufhlzeqqme2lez4h5a

When fatiguing cycling muscles complain, the brain insightfully responds!

Markus Amann, Jerome Dempsey
2009 Physiology News  
We must learn to teach the best attitude to what is not yet known."  ...  Much of the increased risk can be attributed to preterm birth or IUGR, with even late preterm birth (birth at 34-36 weeks gestation) now recognised as carrying significantly increased risks for a variety  ...  During one such dinner Dorothy, I think, wondered aloud why Alan had not won a Nobel Prize. We talked about possible reasons but never imagined that the Prize would be announced the following week.  ... 
doi:10.36866/pn.75.13 fatcat:qca27zqkg5gnnaap6gnytb5zcy

28th Annual Computational Neuroscience Meeting: CNS*2019

2019 BMC Neuroscience  
supercritical Hopf bifurcation, that in presence of the theta forcing is excited, giving rise to gamma oscillations super imposed on the theta rhythm, somehow similarly to what previously found in [8].  ...  We tested two different strategies to control the robot.  ...  This change in cortical connectivity is attenuated following preterm birth and predicts visual performance at two years.  ... 
doi:10.1186/s12868-019-0538-0 fatcat:3pt5qvsh45awzbpwhqwbzrg4su

ACNP 55th Annual Meeting: Panels, Mini-Panels and Study Groups

2016 Neuropsychopharmacology  
The first is multivariate pattern recognition or "machine learning" approaches to developing brain signatures.  ...  basic and clinical research, paving the way for prevention, recovery and cure.  ...  This presentation will describe new machine learning and longitudinal findings showing that deficient activation of these circuits during the resolution of cognitive conflict can classify adolescents with  ... 
doi:10.1038/npp.2016.239 fatcat:wg7pyurlzvhp7bvlmlbxtkunl4

Understanding skeletal muscle hypertrophy: integration of cell signalling

Douglas Bolster, Neil Kubica, Stephen Crozier, David Williamson, Peter Farrell, Scot Kimball, Leonard Jefferson
2004 Physiology News  
OXFORD 1-3 October (Fri-Sun) (Focused meeting) Opening date for receipt of abstracts 5 July Closing date for receipt of abstracts 14 July KING'S COLLEGE LONDON 18-20 December (Sat-Mon) Joint meeting with the  ...  The willingness of senior figures to become involved is an indication of both the importance of the issue and the respect with which the Federation is held.  ...  authors are grateful to Helen Birch for providing the horse tendon samples and to Mary Morgan for her help with the imaging of the tendons.  ... 
doi:10.36866/pn.55.18 fatcat:p4gnllea2fcq5n7uet3jnrxfua

EPMA-World Congress 2015

Jella-Andrea Abraham, Olga Golubnitschaja, Ildar Akhmetov, Russell J. Andrews, Leonidas Quintana, Russell J. Andrews, Babak Baban, Jun Yao Liu, Xu Qin, Tailing Wang, Mahmood S. Mozaffari, Viktoriia V. Bati (+405 others)
2016 The EPMA Journal  
Consequently, an optimal set-up of predictive and prognostic biomarker panels may lead to the changed treatment paradigm from untargeted "treat and wait" to the cost-effective predictive, preventive and  ...  Multilevel diagnostic approach (MLDA) is considered helpful to set-up optimal predictive and prognostic biomarker panel for individualised application of radioembolisation.  ...  Acknowledgements This work was supported by grants from "OeNB Jubiläumsfonds", Life Science Krems, TECNET, the Vienna Science and Technology fund WWTF, and EU FP7 and H2020 funds (RESOLVE and ULTRAPLACAD  ... 
doi:10.1186/s13167-016-0054-6 fatcat:kavq6icxxbfm3fdyww6d42rob4

International Conference onHealth Sciences

2006 Journal of Health and Translational Medicine  
It is not surprising that there are a lot of expectations that this revolution in genetics will pave the way to genomic medicine and gene therapy (1) .  ...  Surfactant replacement is well established in respiratory distress in preterm babies.  ...  is going for mammography, we may need to address the following questions: However, studies have shown that doctors are not well trained to handle such situations (1).  ... 
doi:10.22452/jummec.sp2006no1.1 fatcat:tpdpb2lzibfgnab3kjq6khfid4

2501

Magda Shaheen, Senait Teklehaimanot
2017 Journal of Clinical and Translational Science  
The use of mental health and antidepressant drug were used to indicate the service use.  ...  For the use of mental health services among the depressed group, African-American (AA), ≥60 years old, uninsured and foreign born were less likely to use the mental health service relative to other groups  ...  2184 Evaluating the association among biological, social, and nutritional status on adolescent pregnancy rates, physiology and birth outcomes using electronic health records data Amanda Cheng, Caroline  ... 
doi:10.1017/cts.2017.287 fatcat:yp5uxjopfzhuzovziwsbbhl2au

Abstracts from the 50th European Society of Human Genetics Conference: Electronic Posters

2018 European Journal of Human Genetics  
The clinical utility of array comparative genomic hibridization (CGH) in the prenatal samples has been prove to be effective, but it is still in discussion on how to apply array CGH into clinical service  ...  with previous publications were the patological chomosomal abnormalities detected with array CGH is highly increased when compared with karyoptype.  ...  Furthermore, we have identified as a potential therapeutic target the master regulator CTGF that connects a network of 286 downstream targets to invasion of tumor cells.  ... 
doi:10.1038/s41431-018-0248-6 fatcat:t6rlgbruivelldklufqdlzqmtu

Supplementum 222: Joint annual meeting Swiss Society of Paediatrics and the Swiss Society for Allergology and Immunology, jointly organized with the 4th Lymphoid Tissue Meeting "Focus on Stromal Cells"

2017 Swiss Medical Weekly  
and could not be explained by socio-demographic or individual variables.  ...  We investigated the ability of human LNSCs derived from RA, RA-risk and healthy individuals to sense and respond to pathogens.  ...  The regulation of output from the GC is not well understood.  ... 
doi:10.4414/smw.2017.20424 pmid:33379860 fatcat:bpqm632nhffkjhzwtlemyopusa
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