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Chronobiology Predicts Actual and Proxy Outcomes when Dipping Fails

G. Cornelissen, F. Halberg, K. Otsuka, R.B. Singh, C.-H. Chen
2006 Hypertension  
(time structure) analysis.  ...  prediction limit of clinically healthy peers matched by gender and age had a relative risk of 4 (Figure) .  ... 
doi:10.1161/01.hyp.0000250392.51418.64 pmid:17075031 pmcid:PMC2613012 fatcat:kjdpbnde3vdohju6r2pas2ybau

Circadian and circaseptan (about-weekly) aspects of immigrant Indians' blood pressure and heart rate in California, USA

B. Sundaram, D.C. Holley, G. Cornélissen, D. Naik, R. Hanumansetty, R.B. Singh, K. Otsuka, F. Halberg
2005 Biomedicine and Pharmacotherapy  
In this study, 30 clinically healthy subjects underwent 7-day monitoring and provided a series of findings, including the detection of Circadian Hyper-Amplitude-Tension (CHAT), that is blood pressure overswinging  ...  Time structurally (chronomically) interpreted half-hourly monitoring of blood pressure (BP) and heart rate (HR) for at least 7 days and preferably for 17 days is recommended, separately for a diagnosis  ...  BP aroundthe-clock; • change the timing of medication depending on the individual patient's time structures including circadian and whenever pertinent other rhythms.  ... 
doi:10.1016/s0753-3322(05)80014-9 pmid:16275512 pmcid:PMC2576448 fatcat:k4loyp5obngpvpbbsppuwmq4xq

Falls Risk, Circadian Rhythms and Melatonin: Current Perspectives

Nandu Goswami, Carolina Abulafia, Daniel Vigo, Maximilian Moser, Germaine Cornelissen, Daniel Cardinali
2020 Clinical Interventions in Aging  
Whether one is concerned with disease prediction and prevention or maintenance of healthy aging, the study of circadian rhythms and the broader time structure underlying physiopathology is helpful in terms  ...  Timing the administration of such treatment as a function of circadian (and other) rhythms also could lead to reduction of falls in older persons.  ...  Whether one is concerned with disease prediction and prevention or maintenance of healthy aging, the study of circadian rhythms and the broader time structure underlying physiopathology is helpful in terms  ... 
doi:10.2147/cia.s283342 pmid:33204081 pmcid:PMC7666981 fatcat:mqnnb77zsbbvpn54r3kptskq5u

Annual Conference of the Swiss Society of Sleep Research, Sleep Medicine and Chronobiology (SSSSC) and the Swiss Society of Biological Psychiatry (SSBP). Sleepless Mind. Mindless Sleep? Bern, March 25 and 26, 2009

2009 Neuropsychobiology  
In humans, a functional polymorphism of the gene encoding the adenosine metabolizing enzyme, adenosine deaminase (ADA), predicts duration and intensity of slow wave sleep in healthy individuals (Rétey  ...  In this study, we have for the first time directly compared human fibroblast period length with the free-running period length of human circadian behaviour measured in the same subjects in order to establish  ...  In line with Martin (2007), we suggest that parents of kindergarten children may adjust to child's chronotype over time, and conclude that sleewake patterns of parents and children are associated with  ... 
doi:10.1159/000230666 fatcat:5vvhxhxkkfaujnpz2f35iu44fy


2007 International Journal of Bifurcation and Chaos in Applied Sciences and Engineering  
In this tutorial we present recently developed nonlinear methods of cardiovascular physics and show their potentials to clinically relevant problems in cardiology.  ...  of cardiovascular regulation.  ...  Acknowledgments This work is the result of an interdisciplinary cooperation between different groups in several scientific fields. We thank all our colleagues.  ... 
doi:10.1142/s0218127407019093 fatcat:q5msf4nxcbcwnn24dlzhrfg5xq


F Halberg, G Cornélissen, G Katinas, J Dušek, P Homolka, Z Karpíšek, R P P Sonkowsky, O Schwartzkopff, B Fišer, J Siegelová
2007 Scripta medica  
We illustrate the indispensability of the mapping of rhythm characteristics in broader structures, chronomes, along several or all available different time scales.  ...  The mapping of time structures, chronomes, constitutes an endeavor spawned by chronobiology: chronomics.  ...  There is further a half-yearly component in the circulating melatonin of human pregnancies with intrauterine growth retardation (36) (but not in clinically healthy pregnancies).  ... 
pmid:19710947 pmcid:PMC2731306 fatcat:54zudlscxzhalcw6xfklicntly

Adrenals [chapter]

Erica L.T. van den Akker, Evangelia Charmandari
2010 Yearbook of Paediatric Endocrinology  
of target genes, the role of neuropeptide hormone receptors and microRNAs in the diagnosis and treatment of adrenal cancer, and recent advances in the diagnosis and treatment of congenital adrenal hyperplasia  ...  Emerging themes for this year's chapter include the effect of circadian transcription factors on glucocorticoid receptor action, the implications of ultradian glucocorticoid pulsatility on the expression  ...  These findings suggest that introducing glucocorticoid treatment in women with NC-CAH who want to conceive may improve pregnancy rates.  ... 
doi:10.1159/000320657 fatcat:yw7l5msv7bbrfbjzpam6awbiqa

Circadian Clock-Controlled Checkpoints in the Pathogenesis of Complex Disease

Min-Dian Li, Haoran Xin, Yinglin Yuan, Xinqing Yang, Hongli Li, Dingyuan Tian, Hua Zhang, Zhihui Zhang, Ting-Li Han, Qing Chen, Guangyou Duan, Dapeng Ju (+4 others)
2021 Frontiers in Genetics  
by the circadian clock (named clock-controlled checkpoints) in the pathogenesis of complex disease.  ...  Future studies should focus on devising time-dependent strategies for drug delivery and engagement in well-characterized organs such as the liver, and elucidating fundamental circadian biology in so far  ...  Prediction of the circadian phase in vivo is another important aspect for optimizing the time of clinical treatment.  ... 
doi:10.3389/fgene.2021.721231 pmid:34557221 pmcid:PMC8452875 fatcat:5exlopqpzvd3posb7ftlfhzsea

Ayurveda and the science of aging

Rammohan V. Rao
2017 Journal of Ayurveda and Integrative Medicine  
Since time immemorial, humanity has been concerned with developing and preserving youthful vigor, and extending longevity by stopping or delaying the aging process.  ...  This system of medicine includes therapies for healthy aging so as to create an optimal health and lengthen an individual's healthspan by living in harmony with nature.  ...  Dale Bredesen, Brian Kennedy (Buck Institute for Research on Aging) and Marc Halpern (California College of Ayurveda) for helpful discussions and Rowena Abulencia for administrative assistance.  ... 
doi:10.1016/j.jaim.2017.10.002 pmid:29276113 pmcid:PMC6148064 fatcat:giratd54czf5bps2qaq4xrhy74

Subject index

2004 American Journal of Hypertension  
, 690 Effects of the Angiotensin II Receptor Blockers Telmisartan Versus Valsartan on the Circadian Variation of Blood Pressure, 347 Ethnic Differences in Left Ventricular Structure: Relations to  ...  in Blood Pressure in a Community-Dwelling Population, 1179 Roles of Angiotensin Type 1 and 2 Receptors in Pregnancy-Associated Blood Pressure Changes, 684 Self-Measured Home Blood Pressure in Predicting  ... 
doi:10.1016/s0895-7061(04)01131-8 fatcat:zeurdzdbbbhpdm75ri42kztgyy

Family Dynamics in Sleep Health and Hypertension

Heather E. Gunn, Kenda R. Eberhardt
2019 Current Hypertension Reports  
Changes in family structure could contribute to more negative events, which are also predictive of BMI.  ...  The timing of family-based activities (such as meal time) have the propensity to influence an individual's daily social rhythmicity, and in turn, their endogenous circadian rhythms.  ...  latency; TIB = time in bed; CAR = cortisol awakening response.  ... 
doi:10.1007/s11906-019-0944-9 pmid:30982174 pmcid:PMC6501837 fatcat:jzncih5kzrhoxkcc357rwj4gg4

Emotional memory in pregnant women at risk for postpartum depression

Marissa E. Williams, Suzanna Becker, Margaret C. McKinnon, Queenie Wong, Lauren E. Cudney, Meir Steiner, Benicio N. Frey
2015 Psychiatry Research  
16.3 16.3 16.3 17 17.3 17.3 19 19 Time of day (hour) salivary cortisol Time of day (hour) Circadian rhythm of salivary cortisol in non-pregnant healthy women CORTnumber 2 key if you think the picture  ...  secretion (AUC G ) at baseline (time -1) in non-Figure 3. j) Area under the cortisol curve (AUC G ) for non-pregnant healthy women pregnant healthy women (n=20) Circadian rhythm of salivary cortisol in  ...  Instructions for the emotional memory task (EMT): In this test you will see a series of 216 images. Some of these images are those you saw last week, others are not.  ... 
doi:10.1016/j.psychres.2015.08.003 pmid:26272023 fatcat:faa3b6bsxvfafnhokraviw4hje

Pilot Study of Circulating Prolactin Levels and Endothelial Function in Men With Hypertension

K. S. Stamatelopoulos, G. A. Georgiopoulos, P. P. Sfikakis, G. Kollias, E. Manios, E. Mantzou, K. Kyrkou, N. Zakopoulos, C. M. Papamichael, M. Alevizaki
2011 American Journal of Hypertension  
Considering that secretion of prolactin presents circadian rhythmicity, we tested the hypothesis that in patients with hypertension, who present diurnal variation in their endothelial function as well,  ...  Hyperprolactinemia has been recently associated with hypertension and endothelial dysfunction in humans, confirming animal studies performed in the 1970s that showed high prolactin levels to exert positive  ...  Morning attenuation of FMD has been demonstrated not only in hypertension, but also in healthy individuals 20 and other conditions, such as menopause and heart failure. 32, 33 The circadian changes  ... 
doi:10.1038/ajh.2011.16 pmid:21331059 fatcat:gopyg62tavfh5chbjjsuypogxe

Sleep and Alcohol Use in Women

Sarah M Inkelis
2020 Alcohol research : current reviews  
Historically, studies of AUD have included few, if any, women in their samples.  ...  Insomnia not only is a pathway toward alcohol consumption but also is related to increased risk of relapse, psychosocial impairment, decreased quality of life, and suicidal ideation in individuals with  ...  The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.  ... 
doi:10.35946/arcr.v40.2.13 pmid:32685340 pmcid:PMC7359817 fatcat:nabgukyk6rcq5iomkv7qispuom

Low 24-Hour Adiponectin and High Nocturnal Leptin Concentrations in a Case-Control Study of Community-Dwelling Premenopausal Women With Major Depressive Disorder

Giovanni Cizza, Vi T. Nguyen, Farideh Eskandari, Zhigang Duan, Elizabeth C. Wright, James C. Reynolds, Rexford S. Ahima, Marc R. Blackman
2010 Journal of Clinical Psychiatry  
Objective-Major depressive disorder (MDD) is associated with immune system dysfunction and disruption of multiple circadian systems.  ...  Our goals were to: A) establish whether premenopausal women with MDD exhibit decreased plasma adiponectin concentrations and/or disruption of circadian adiponectin rhythmicity; B) assess whether there  ...  Acknowledgments The study was fully supported by the Intramural Research Programs of the National Institute of Mental Health (NIMH); National Institute of Diabetes, Digestive and Kidney Diseases (NIDDK  ... 
doi:10.4088/jcp.09m05314blu pmid:20492842 pmcid:PMC3277206 fatcat:43r2jtegozbitia4hi5tgmzo44
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