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High precision magnetically driven microtools with ultrasonic vibration for enucleation of oocytes
2010
2010 International Symposium on Micro-NanoMechatronics and Human Science
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This paper presents innovative driving method for the magnetically driven microtools (MMT) which is micrometer positioning accuracy by horizontally arranged permanent magnets. ...
A piezoelectric ceramic is used to induce nanoscale vibration to the microfluidic chip to reduce the friction on the MMT. The enucleation process has been conducted by the dual arm MMTs. ...
ACKNOWLEDGEMENT This work is partially supported by JST-SENTAN and the Nagoya University Global COE program for Education and Research of Micro-Nano Mechatronics. ...
doi:10.1109/mhs.2010.5669580
fatcat:nqwmrgu2bbcmzehlzwxpfvipq4
On-Chip Enucleation of Bovine Oocytes using Microrobot-Assisted Flow-Speed Control
2013
Micromachines
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In this study, we developed a microfluidic chip with a magnetically driven microrobot for oocyte enucleation. ...
A microfluidic system was specially designed for enucleation, and the microrobot actively controls the local flow-speed distribution in the microfluidic chip. ...
Acknowledgements This work is partially supported by SENTAN, JST; the Nagoya University Global COE program for Education and Research of Micro-Nano Mechatronics; and Scientific Research from the Ministry ...
doi:10.3390/mi4020272
fatcat:nyvx5qqjcrbsxh6rnyndvuztii
High-Speed Magnetic Microrobot Actuation in a Microfluidic Chip by a Fine V-Groove Surface
2013
IEEE Transactions on robotics
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This paper presents high-speed microrobotic actuation driven by permanent magnets in a microfluidic chip. ...
Index Terms-Friction reduction, high speed, lab on a chip, magnetically driven microtool (MMT), microfluidics, microrobot. ...
FABRICATION OF THE SI-NI COMPOSITE MAGNETICALLY DRIVEN MICROTOOL WITH AN OPTIMUM RIBLET SURFACE In order to produce the optimum riblet shape, precise 3-D fabrication is required. ...
doi:10.1109/tro.2012.2228310
fatcat:wzrg4qvienapxaezbxahdulqnm
Magnetically Driven Bionic Millirobots with a Low-Delay Automated Actuation System for Bioparticles Manipulation
2020
Micromachines
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This paper presents a semi-automatic actuation system which can achieve bio-particles tracking, transportation, and high-precision motion control of robots in a microfluidic chip. ...
In biotechnology, precise transportation of cells is used for the enucleation, microinjection, and investigation of the characteristics of a single cell. ...
Conflicts of Interest: The authors declare no conflict of interest. ...
doi:10.3390/mi11020231
pmid:32102365
pmcid:PMC7074837
fatcat:bj3qmd5twvd25javylsowjwthq
Cell Injection Millirobot Development and Evaluation in Microfluidic Chip
2018
Micromachines
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We propose an innovative design of millirobot, which can achieve donor cell suction, delivery, and injection in a mammalian oocyte on a microfluidic chip. ...
We demonstrate the effectiveness of the proposed millirobot through an experiment of the absorption and ejection of 20-µm particles from the nozzle using magnetic control in a microfluidic chip. ...
Conflicts of Interest: The authors declare no conflict of interest. ...
doi:10.3390/mi9110590
pmid:30428554
pmcid:PMC6266326
fatcat:56tsba7qq5evnpguple3wqiv7q
Biomedical Applications of Untethered Mobile Milli/Microrobots
2015
Proceedings of the IEEE
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As the robot size goes down to the order of a single cell, previously inaccessible body sites would become available for high-resolution in situ and in vivo manipulations. ...
We put a special emphasis on the potential impacts of biomedical microrobots in the near future. ...
Furthermore, Hagiwara et al. proposed a magnetically driven microtools that was able to orient, position and cut single cell [126] . These functions were used to enucleate the oocyte [127] . ...
doi:10.1109/jproc.2014.2385105
pmid:27746484
pmcid:PMC5063027
fatcat:lsvefsokvnhu3mjnf7576t3fyq
Analysis and suppression of residual vibration in microhand for high-speed single-cell manipulation
2013
International Journal of Mechatronics and Automation
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Second, precise motion throughout a large workspace for the transportation of microobjects in the limited space of a microscope is another arduous task. ...
In this study, we propose multiscalability concept, i.e., a large workspace with precise positioning for the grasping and transportation of multisized microobjects. ...
Magnetic driven microtools (MMT) were developed to provide many microfluidic functions, such as those of manipulation, sorting, dispensing, etc. [21, 22] . ...
doi:10.1504/ijma.2013.053402
fatcat:xgqdqjntkvgq3nqe5mp3i4fwbi
Micro-scale Instruments Applied to a Bovine Nuclear Transfer System
[article]
2010
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Tools were developed for two areas of cell handling: cell fusion and cell transportation. Designs suitable for implementation in microscale lab-on-chip systems were evaluated. ...
Many miniaturised lab-on-chip systems rely on cell transportation. One illustration in the baseline procedure is the on-chip transport of cells to the cell fusion device. ...
[133] developed a microfluidic device specifically for separation of the oocyte from surrounding cumulus cells. ...
doi:10.26021/2780
fatcat:dda3sr73orgkbjthmcqfadvhje