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Follow-up and Surveillance of the Patient With Lung Cancer After Curative-Intent Therapy

Henri G. Colt, Septimiu D. Murgu, Robert J. Korst, Christopher G. Slatore, Michael Unger, Silvia Quadrelli
2013 Chest  
These guidelines are an update of the evidence-based recommendations for follow-up and surveillance of patients after curative-intent therapy for lung cancer.  ...  In patients undergoing curative-intent surgical resection of non-small cell lung cancer, chest CT imaging performed at designated time intervals after resection is suggested for detecting recurrence.  ...  The Role of Tumor Markers In solid tumors other than lung cancer, biomarkers help in diagnosis, determine response to treatment, and serve as a tool for detecting recurrence.  ... 
doi:10.1378/chest.12-2365 pmid:23649451 fatcat:ckjkiyzuqfea5amf5eklffxeua

Malignant pleural mesothelioma: predictors and staging

William G. Richards
2017 Annals of Translational Medicine  
Validation of staging criteria has been difficult given the rarity of the disease and the fact that only a minority of patients undergo surgical resection with pathological examination of their tumors.  ...  Malignant pleural mesothelioma remains a rapidly fatal cancer with few effective therapies. Unusual anatomic features complicate determination of stage and prognosis for individual patients.  ...  Footnote Conflicts of Interest: The author has no conflicts of interest to declare.  ... 
doi:10.21037/atm.2017.06.26 pmid:28706911 pmcid:PMC5497102 fatcat:yw5ou455fne4hi7uxqkqyynney

Radiomics for liver tumours

Constantin Dreher, Philipp Linde, Judit Boda-Heggemann, Bettina Baessler
2020 Strahlentherapie und Onkologie (Print)  
The use of big data such as radiomics and the integration of artificial intelligence techniques have the potential to further improve image-based treatment planning and structured follow-up, with outcome  ...  Through use of quantitative imaging data, more tailored and tumour-specific diagnostic work-up and individualized treatment concepts may be applied for oncologic patients in the future.  ...  from CT images may be a potential imag- ing biomarker for liver cancer inva- sion and enable accurate prediction of HCC recurrence after LT Zhao et al  ... 
doi:10.1007/s00066-020-01615-x pmid:32296901 pmcid:PMC7498486 fatcat:urkoadbedrhqnj5tv4yhxfyyyq

Prognostic Value of 18F-FDG PET/CT Metabolic Parameters in Surgically Treated Stage I Lung Adenocarcinoma Patients

Davide Tosi, Sara Pieropan, Maria Cattoni, Gianluca Bonitta, Sara Franzi, Paolo Mendogni, Andrea Imperatori, Nicola Rotolo, Massimo Castellani, Marco Cuzzocrea, Ilaria Schiorlin, Sabrina Casagrande (+3 others)
2021 Clinical Nuclear Medicine  
SUVmean and MTV were calculated using SUV threshold of 41% of SUVmax; the total lesion glycolysis (TLG) was calculated as the product of SUVmean and MTV.  ...  This article aims to explore the prognostic role of 18F-FDG PET/CT metabolic parameters in stage I lung adenocarcinoma patients.  ...  A recently developed method for the identification of imaging biomarkers is the radiomic analysis, a methodology that extracts a large number of quantitative features using mathematical models. 22 Ahn  ... 
doi:10.1097/rlu.0000000000003714 pmid:34034316 fatcat:4oall6dfwvhcxonwqfqdf7ujwq

Impact of PET/CT for Assessing Response to Immunotherapy—A Clinical Perspective

David Lang, Gerald Wahl, Nikolaus Poier, Sebastian Graf, David Kiesl, Bernd Lamprecht, Michael Gabriel
2020 Journal of Clinical Medicine  
Multiple promising studies concerning ICI response assessment or prediction using biomarkers derived from PET/CT alone or as composite biomarkers have been identified for various malignancies and disease  ...  Cancer immunotherapy using immune-checkpoint inhibitors (ICI) has revolutionized the therapeutic landscape of various malignancies like non-small-cell lung cancer or melanoma.  ...  Seban et al., for example, proclaimed the value of quantitative baseline 18 F-FDG PET/CT biomarkers as a prognostic tool in patients with cutaneous and mucosal melanoma.  ... 
doi:10.3390/jcm9113483 pmid:33126715 pmcid:PMC7694130 fatcat:m2d6tqmt5nbalppenhuxxhqrwu

Circulating Tumor DNA in Colorectal Cancer—From Concept to Clinic

Matthew Loft, Azim Jalali, Peter Gibbs, Jeanne Tie, Walter and Eliza Hall Institute of Medical Research, Parkville, Australia, The University of Melbourne, Parkville, Australia, Western Health, Footscray, Australia, Peter MacCallum Cancer Centre, Parkville, Australia
2019 Oncology & Hematology Review (US)  
A dvances in the ability to detect molecular alterations in cancer have led to the development of personalized oncology treatments in colorectal cancer.  ...  The advent of liquid biopsies, in the form of circulating tumor DNA (ctDNA), has many potential clinical applications including non-invasive methods of tumor genotyping, prognostication, monitoring treatment  ...  In A significant proportion of patients with early stage solid malignancies will develop recurrence after curative intent surgical resection of their primary tumor.  ... 
doi:10.17925/ohr.2019.15.1.33 fatcat:x27suedakzhofhy5pj4y2kcvke

Prediction and diagnosis of interval metastasis after neoadjuvant chemoradiotherapy for oesophageal cancer using 18F-FDG PET/CT

Lucas Goense, Jelle P. Ruurda, Brett W. Carter, Penny Fang, Linus Ho, Gert J. Meijer, Richard van Hillegersberg, Wayne L. Hofstetter, Steven H. Lin
2018 European Journal of Nuclear Medicine and Molecular Imaging  
This study aimed to evaluate the diagnostic performance of 18 F-FDG PET/CT for the detection of interval metastasis and to identify predictors of interval metastases in a large cohort of oesophageal cancer  ...  The provided prediction score may stratify risk of developing interval metastasis, and could be used to prioritize additional restaging modalities for patients most likely to benefit.  ...  Based on these findings, a prediction score was developed which may provide physicians a tool for objectively assessing the risk of interval metastasis in patients with oesophageal cancer.  ... 
doi:10.1007/s00259-018-4011-6 pmid:29663014 pmcid:PMC6097755 fatcat:b5x4h2mkangszgud7nmigmfpdm

The 8th Asia-Pacific Primary Liver Cancer Expert Meeting (APPLE 2017). The Art & Science of Conquering Liver Cancer. Singapore, July 14-16, 2017: Abstracts

2017 Liver Cancer  
It serves as a platform for the design of immunomonitoring and immunotherapy for cancers.  ...  A new guideline for pathological diagnosis of liver cancer has recently been published. The clinical diagnosis of HCC is mainly based on imaging assessment.  ...  OTR-10076 Substaging of Barcelona Clinic Liver Cancer Stage C Hepatocellular Carcinoma with a National-Wide Validation  ... 
doi:10.1159/000478029 fatcat:mq43zbb47jglhhsejx5iudbrwu

MINI ORAL SESSIONS

2015 Journal of Thoracic Oncology  
a cohort of resected lung cancers who had multiple nodules.  ...  Results: From April 1999 to February 2013, a total of 2925 lung cancer resection were performed.  ...  PROs were assessed at baseline and Day 1 of treatment cycles 2, 3, and every two cycles thereafter (1 cycle=28 days), using the Lung Cancer Symptom Scale (LCSS) and EORTC quality of life and lung cancer  ... 
doi:10.1016/s1556-0864(16)30011-9 fatcat:nlhtgbimt5fu5dx4syerr2hjmu

Proceedings of the International Cancer Imaging Society (ICIS) 18th Annual Teaching Course

2018 Cancer Imaging  
Distinguishing radiation fibrosis from tumour recurrence after stereotactic ablative radiotherapy (SABR) for lung cancer: a quantitative analysis of CT density changes.  ...  In this regard, CT and MRI are increasingly used to assess the response of locally advanced pancreatic cancers to neoadjuvant treatment, and the potential for surgical resection.  ...  This study aims to predict MSI status of CRC using quantitative image analysis of preoperative CT.  ... 
doi:10.1186/s40644-018-0160-x fatcat:l3fdy44aunejnfamsnka5hfiwu

The 6th Asia-Pacific Primary Liver Cancer Expert Meeting (APPLE 2015), Evidence and Consensus on HCC Management. Osaka, Japan, July 3-5, 2015: Abstracts

2015 Liver Cancer  
P2-22 VF Map Scores (Virtual Touch Quantification, Fasting Plasma Glucose, Male, Age, Platelets) for Prediction of Hepato-Carcinogenesis  ...  Acknowledgement: We would like to express the deepest appreciation to Dr. Yada who provided valuable ultrasound-based TE data.  ...  Recently, some patients with early staged HCC insist on LDLT as a primary treatment because of the high recurrence risk and potential non-transplantable recurrence after other treatment including resection  ... 
doi:10.1159/000367745 fatcat:cti4zaoytncetoc4oft7l3j65u

Appropriate Use Criteria for18F-FDG PET/CT in Restaging and Treatment Response Assessment of Malignant Disease

Hossein Jadvar, Patrick M. Colletti, Roberto Delgado-Bolton, Giuseppe Esposito, Bernd J. Krause, Andrei H. Iagaru, Helen Nadel, David I. Quinn, Eric Rohren, Rathan M. Subramaniam, Katherine Zukotynski, Julie Kauffman (+2 others)
2017 Journal of Nuclear Medicine  
The quality (based on the risk of bias) for each study was categorized as "good," "fair," or "poor" by using the predefined criteria for each study design.  ...  The lifetime risk of developing lung cancer is approximately 6.6% for men and women, based on 2010-2012 data (90).  ...  HL: Hodgkin lymphoma Lymphoma (178): A cancer of part of the immune system called the lymph system. There are many types of lymphoma such as Hodgkin lymphoma (179) and non-Hodgkin lymphoma (178).  ... 
doi:10.2967/jnumed.117.197988 pmid:29025980 fatcat:lzfu6ailtvg47fydwujkiuj3c4

INVITED ABSTRACTS

2015 Journal of Thoracic Oncology  
Until then, surgeons should be prudent in performing a sublobar resection as a radical resection for lung cancer. [8] specificity of the risk models which use clinical variables alone.  ...  The only risk prediction model so far utilised in the recruitment of participants into a CT Lung Cancer Screening RCT, is the LLP v2 risk model in the pilot UK lung cancer screening trial (UKLS) [5] .  ...  FAK is overexpressed with increasing activity in many human cancers, associated to a low tumor expression of the Merlin molecule, a potential predictive biomarker of FAK inhibitors.  ... 
doi:10.1016/s1556-0864(16)30009-0 fatcat:dp7nw6kfnnekjimnadoi5bexpa

Defining Oligometastatic Disease from a Radiation Oncology perspective: an ESTRO-ASTRO Consensus Document

Yolande Lievens, Matthias Guckenberger, Daniel Gomez, Morten Hoyer, Puneeth Iyengar, Isabelle Kindts, Alejandra Méndez Romero, Daan Nevens, David Palma, Catherine Park, Umberto Ricardi, Marta Scorsetti (+2 others)
2020 Radiotherapy and Oncology  
meaningful radiotherapy with curative intent to all metastatic sites as a minimum requirement for defining OMD in the context of radiotherapy.  ...  Subsequent consensus opinion, using a Delphi process, highlighted the current state of evidence and the limitations in the available literature.  ...  Salama and thank them for their valuable comments and improvements to the manuscript. Appendix A.  ... 
doi:10.1016/j.radonc.2020.04.003 pmid:32388150 fatcat:7ahv44egx5c2jjonzfw5y3i63q

Abstracts

2010 Journal of Thoracic Oncology  
curative radiotherapy for locoregionally recurrent non-small cell lung cancer (NSCLC).  ...  242P RADIOTHERAPY FOR LOCOREGIONAL RECURRENT NON-SMALL CELL LUNG CANCER J. Kim 1 , M. Kim 2 , N. Jang 1 , J.  ...  Although lung cancer screening and surgical resection for early stage lung cancer may offer a potential curative treatment, it is not free of complications.  ... 
doi:10.1097/01.jto.0000372622.81561.0e fatcat:yeedmnacvzegvon22pk6g2cdsu
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