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Phosphate Sink Containing Two-Component Signaling Systems as Tunable Threshold Devices

Munia Amin, Varun B. Kothamachu, Elisenda Feliu, Birgit E. Scharf, Steven L. Porter, Orkun S. Soyer, Feilim Mac Gabhann
2014 PLoS Computational Biology  
These findings show that the one HK-two RR motif allows bacteria and yeast to implement tunable switch-like signal processing and provides an ideal basis for developing threshold devices for synthetic  ...  We show that, under the experimentally observed parameters from bacteria and yeast, this motif not only allows rapid signal termination, whereby one of the RRs acts as a phosphate sink towards the other  ...  devices using two-component signalling proteins.  ... 
doi:10.1371/journal.pcbi.1003890 pmid:25357192 pmcid:PMC4214558 fatcat:yix5zdt3brbx7ad63d6wbfka7y

Controlled release of dry reagents in porous media for tunable temporal and spatial distribution upon rehydration

Gina E. Fridley, Huy Q. Le, Elain Fu, Paul Yager
2012 Lab on a Chip  
Third, reagents are reconstituted sequentially from dry storage depots with tunable delivery times.  ...  Finally, the utility of these control methods is demonstrated in the context of real-time reagent rehydration and mixing on a porous device.  ...  DGE -0718124, as well as NIH (EB000252). Additional funding was provided by the University of Washington Bioengineering Department.  ... 
doi:10.1039/c2lc40785j pmid:22960691 pmcid:PMC3489279 fatcat:d3gb22souvgpjbgtgy5yrqnk7a

Laser amplifier development for IPDA Lidar measurements of CO2from space

Anthony W. Yu, James B. Abshire, Mark Storm, Alexander Betin, W. Andrew Clarkson, Ramesh K. Shori
2015 Solid State Lasers XXIV: Technology and Devices  
It uses two tunable pulsed laser transmitters allowing simultaneous measurement of a single CO 2 absorption line in the 1570 nm band, absorption of an O 2 line pair in the oxygen A-band (765 nm), and atmospheric  ...  To meet the laser energy requirements we have pursued two parallel power-scaling approaches for the space laser.  ...  ACKNOWLEDEMENT The authors would like to acknowledge the support from NASA Earth Science Technology Office (ESTO) under the Advanced Component Technology (ACT), Innovative Incubator Program (IIP) and the  ... 
doi:10.1117/12.2080792 fatcat:f4llbrmm45bdnmpa7c3fh2ivli

Chemical sensors based on quantum cascade lasers

A.A. Kosterev, F.K. Tittel
2002 IEEE Journal of Quantum Electronics  
The recent availability of novel pulsed and CW quantum cascade distributed feedback (QC-DFB) lasers as mid-infrared spectroscopic sources address this need.  ...  The sensor described in [29] used the same QC-DFB laser at m [28] as a spectroscopic source and a two-channel configuration with a 1-m optical pathlength inside a cell culture container.  ...  Another issue is the limited tunability of each QC-DFB laser, which restricts the feasibility of multi-component chemical sensing.  ... 
doi:10.1109/jqe.2002.1005408 fatcat:k5h2lkv7bbhx7oeyfwk6roy5le

Chemical sensors based on quantum cascade lasers

Frank K. Tittel, Anatoliy A. Kosterev, Michel Rochat, Mattias Beck, Jerome Faist, Alan Fried
2002 Diode Lasers and Applications in Atmospheric Sensing  
The recent availability of novel pulsed and CW quantum cascade distributed feedback (QC-DFB) lasers as mid-infrared spectroscopic sources address this need.  ...  The sensor described in [29] used the same QC-DFB laser at m [28] as a spectroscopic source and a two-channel configuration with a 1-m optical pathlength inside a cell culture container.  ...  Another issue is the limited tunability of each QC-DFB laser, which restricts the feasibility of multi-component chemical sensing.  ... 
doi:10.1117/12.452087 fatcat:lwyxriqpnzaldfruteh5pgeocu

An Overview on Quantum Cascade Lasers: Origins and Development [chapter]

Raul Pecharroman-Gallego
2017 Quantum Cascade Lasers  
Materials used, as well as growth methods, are also described. The possibility of developing GaN-based QCLs is also shown.  ...  Summarizing, the applications of these structures cover a broad range, including spectroscopy, free-space communication, as well as applications to near-space radar and chemical/biological detection.  ...  Hence, a QCL device might be priced below the market, which can have negative consequences that can reach the component supplier.  ... 
doi:10.5772/65003 fatcat:uyexish2jjg4zl7peg67w6xcq4

Spaceborne laser instruments for high-resolution mapping

Anthony W. Yu, Michael A. Krainak, David J. Harding, James B. Abshire, Xiaoli Sun, Susan Valett, John Cavanaugh, Luis Ramos-Izquierdo, W. Andrew Clarkson, Norman Hodgson, Ramesh K. Shori
2010 Solid State Lasers XIX: Technology and Devices  
Simulations of thermal performance of the disk and the heat sink are also included.  ...  Edge-pumping [1] allows for reduced doping of crystals with laser ions, which translates to lower lasing threshold in quasi-3 level materials.  ...  well as higher damage threshold than AGS.  ... 
doi:10.1117/12.843191 fatcat:6ouzsdkdknh63ordfsktdz3lqq

Optical Waveguides and Integrated Optical Devices for Medical Diagnosis, Health Monitoring and Light Therapies

Jiayu Wang, Jianfei Dong
2020 Sensors  
Thirdly, wearable optical sensing devices based on light sensing methods such as colorimetry, fluorescence and luminescence are discussed.  ...  Optical waveguides and integrated optical devices are promising solutions for many applications, such as medical diagnosis, health monitoring and light therapies.  ...  As the media between light and tissues, optical sensing modules in these devices function as indispensable components.  ... 
doi:10.3390/s20143981 pmid:32709072 fatcat:6plv2ikpx5cybllqnyyns2fzka

Laser Sources for Confocal Microscopy [chapter]

Enrico Gratton, Martin J. vandeVen
2006 Handbook Of Biological Confocal Microscopy  
Randomly polarized beams contain two orthogonal components but the phase and ratio of the two components vary rapidly in time, creating polarization noise.  ...  A sufficient number of eye protection devices should always be at hand when laser system components have to be repositioned or realigned.  ... 
doi:10.1007/978-0-387-45524-2_5 fatcat:2knlshddpnf4vcr6ee22ht4nye

Laser Sources for Confocal Microscopy [chapter]

Enrico Gratton, Martin J. VandeVen
1990 Handbook of Biological Confocal Microscopy  
Randomly polarized beams contain two orthogonal components but the phase and ratio of the two components vary rapidly in time, creating polarization noise.  ...  A sufficient number of eye protection devices should always be at hand when laser system components have to be repositioned or realigned.  ... 
doi:10.1007/978-1-4615-7133-9_5 fatcat:m3tmtfnws5dz5e7elfx3r3ye2u

Laser Sources for Confocal Microscopy [chapter]

Enrico Gratton, Martin J. vandeVen
1995 Handbook of Biological Confocal Microscopy  
Randomly polarized beams contain two orthogonal components but the phase and ratio of the two components vary rapidly in time, creating polarization noise.  ...  A sufficient number of eye protection devices should always be at hand when laser system components have to be repositioned or realigned.  ... 
doi:10.1007/978-1-4757-5348-6_5 fatcat:4dust3ercjh43ouyrgs72tknpm

VECSEL systems for quantum information processing with trapped beryllium ions [article]

S. C. Burd, J.-P. Penttinen, P.-Y. Hou, H. M. Knaack, S. Ranta, M. Mäki, E. Kantola, M. Guina, D. H. Slichter, D. Leibfried, A. C. Wilson
2020 arXiv   pre-print
Two vertical-external-cavity surface-emitting laser (VECSEL) systems producing ultraviolet (UV) radiation at 235 nm and 313 nm are demonstrated.  ...  Each system consists of a compact, single-frequency, continuous-wave VECSEL producing high-power near-infrared light, tunable over tens of nanometers.  ...  Conclusion In summary, we have presented two widely-tunable VECSELbased laser sources capable of implementing tasks required for quantum information processing experiments involving trapped 9 Be + ions  ... 
arXiv:2003.09060v1 fatcat:olthdli67nc4xc7d3bvuei74kq

Narrowband photon pairs with independent frequency tuning for quantum light-matter interactions [article]

Vindhiya Prakash, Lorena C. Bianchet, Marc T. Cuairan, Pau Gomez, Natalia Bruno, Morgan W. Mitchell
2019 arXiv   pre-print
The techniques are readily extensible to other material systems.  ...  Type-II phase matching, a tuneable-birefringence resonator, MHz-resolution pump tuning, and tuneable Fabry-Perot filters are used to achieve independent signal and idler tuning.  ...  Alvaro Cuevas for contributions to development of the system, Dr. Simon Coop for the valuable discussions on microcontrollers and Natália Alves for discussions and feedback on the manuscript.  ... 
arXiv:1911.00056v1 fatcat:mxaaqbewbfbb5oqahznyjgt73u

High-speed intravascular photoacoustic imaging at 17 μm with a KTP-based OPO

Jie Hui, Qianhuan Yu, Teng Ma, Pu Wang, Yingchun Cao, Rebecca S. Bruning, Yueqiao Qu, Zhongping Chen, Qifa Zhou, Michael Sturek, Ji-Xin Cheng, Weibiao Chen
2015 Biomedical Optics Express  
Here, we demonstrate a potassium titanyl phosphate (KTP)-based optical parametric oscillator with output pulse energy up to 2 mJ at a wavelength of 1724 nm and with a repetition rate of 500 Hz.  ...  In the laser system, the length of the OPO cavity was designed to be as short as 44 mm, since a short length leads to a low conversion threshold power density.  ...  Both PA and US signals were collected and reconstructed as IVPA (Fig. 4(a) ) and IVUS (Fig. 4(b) ) images through the high-speed IVPA imaging system.  ... 
doi:10.1364/boe.6.004557 pmid:26601018 pmcid:PMC4646562 fatcat:3dxhdyb2xnajdppwfs3amqv2ei

A Survey of Molecular Communication in Cell Biology: Establishing a New Hierarchy for Interdisciplinary Applications [article]

Dadi Bi, Apostolos Almpanis, Adam Noel, Yansha Deng, Robert Schober
2020 arXiv   pre-print
Molecular communication (MC) engineering is inspired by the use of chemical signals as information carriers in cell biology.  ...  The biological nature of chemical signaling makes MC a promising methodology for interdisciplinary applications requiring communication between cells and other microscale devices.  ...  for a tunable release of signal molecules.  ... 
arXiv:2009.00090v1 fatcat:5fhpk7dpmvc35b44ysr4srqbc4
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