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Phenome-wide Association Studies on Cardiovascular Health and Fatty Acids Considering PhenotypeQuality Control Practices for Epidemiological Data

Kristin Passero, Xi He, Jiayan Zhou, Bertram Müller-Myhsok, Marcus E. Kleber, Winfried März, Molly A. Hall
2020 Pacific Symposium on Biocomputing  
Using data from the Ludwigshafen Risk and Cardiovascular (LURIC) Health Study we ran two PheWAS, one on cardiac-related diseases and the other on polyunsaturated fatty acids levels.  ...  Seven SNPs were significant in association with dihomo-γ-linolenic acid, of which five were within fatty acid desaturases FADS1 and FADS2.  ...  Acknowledgments Genotyping of the LURIC study participants was supported by the 7 th Framework Program AtheroRemo (grant agreement number 201668) of the European Union.  ... 
dblp:conf/psb/PasseroHZMKMH20 fatcat:3volu6bzejbopcqm2lvsevebre