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Geologic Maps of Antarctica, by Campbell Craddock
1971
Arctic
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Peter I . Barrett G. Power GEOLOGIC MAPS OF ANTARCTICA. BY CAMPBELL CRADWCK et al. Antarctic Map Folio Series, Folio 12. ...
doi:10.14430/arctic3312
fatcat:dxvmhtyr3fhphpm4hl257ixt2m
ABSOLUTE cancer genomics
2012
Nature Biotechnology
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Calculating absolute copy numbers in cancer genome sequences identifies disease-associated genes and provides insights into tumor evolution and heterogeneity. Cancer genomes may contain a wide array of aberrations-point mutations, small insertions and deletions, genomic rearrangements and viral-genome insertions-all of which can be detected by deep sequencing of tumor samples. However, we are only just beginning to understand how to use such data to study the processes underlying oncogenesis.
doi:10.1038/nbt.2293
pmid:22781683
pmcid:PMC3428863
fatcat:sfcld2woi5fergpoxlctj4wnrq
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... a recent paper in Nature Biotechnology, Carter et al. 1 show that quantifying copy number changes
Response
2010
Neurosurgical Focus
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Fahlbusch R, Honegger J, Paulus W, Huk W, Buchfelder M: Sur gical treatment of craniopharyngiomas: experience with 168 patients. J Neurosurg 90:237-250, 1999 5. ...
J Clin Endocrinol Metab 81:1169-1172, 1996 3. Bülow B, Hagmar L, Mikoczy Z, Nordström CH, Erfurth EM: Increased cerebrovascular mortality in patients with hypopituitarism. ...
doi:10.3171/2010.3.focus1069
fatcat:4z7d7xr5irdetpf3537vqx7hee
Lung Transplantation for Williams-Campbell Syndrome With a Probable Familial Association
2012
Respiratory care
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Williams-Campbell syndrome is a rare disorder characterized by deficiency of subsegmental bronchial cartilage and development of airway collapse and bronchiectasis that may subsequently progress to respiratory ...
We report the first lung transplant with prolonged survival, approaching 10 years, in a patient with Williams-Campbell syndrome, and provide further evidence to support a familial association. ...
Introduction Williams-Campbell syndrome (WCS) is a rare disorder characterized by deficiency of cartilage in subsegmental bronchi (4th to 6th order bronchi) with subsequent development of airway collapse ...
doi:10.4187/respcare.01484
pmid:22348466
pmcid:PMC4066632
fatcat:6tqnem67rzf7lhnbcu7j467sde
The cancer genome
2009
Nature
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Most of the known rearranged cancer Box 1 j Driver and passenger mutations All cancers arise as a result of somatically acquired changes in the DNA of cancer cells. ...
doi:10.1038/nature07943
pmid:19360079
pmcid:PMC2821689
fatcat:5cppesihnvgozpr4rtx5reiwyi
Rabies
1990
Journal of Animal Ecology
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GILLER
J. B. Campbell & K. M. Charlton (Eds) (1988). Rabies. Pp. xii+431. Kluwer Academic Publishers, Boston. Price not given. ...
PETER HUDSON
379 ...
doi:10.2307/5180
fatcat:k6nzzf6cjfahho66ybx36wnhyu
Une exigence de qualité
1996
Revue internationale d'éducation Sèvres
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Universal Patterns Of Selection In Cancer And Somatic Tissues
[article]
2017
bioRxiv
pre-print
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Stratton, Peter J. Campbell. Quality controls and use of TCGA calls in five cancer types 2.4. Calling of copy number changes 3. ...
Dawson, Kerstin Haase, Peter Van Loo, Helen Davies, Michael R. ...
doi:10.1101/132324
fatcat:ncy2ej6jinckvamlnwjqmgx6gm
Pan-cancer analysis of whole genomes
[article]
2017
bioRxiv
pre-print
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Roadmap Epigenomics Consortium, Kundaje A, Meuleman W, Ernst J, Scientific Collaboration and Discovery. Cell 167, 1145-1149 (2016). ...
and other ef ects Kim AR, Kulkarni A, Li D, Lowdon R, Elliott G, Mercer TR, Neph SJ, Onuchic V, Polak P, Rajagopal N, Ray P, Sallari RC, Siebenthall KT, Sinnott-Armstrong NA, Stevens M, Thurman RE, Wu J, ...
doi:10.1101/162784
fatcat:5kyv666yxzfv5cfvpsrbmbyxea
Evolution of the cancer genome
2012
Nature reviews genetics
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Author manuscript; available in PMC 2013 May 29. and Campbell
Page 6
Panel a is adapted, with permission, from REF. 21 © (2012) Macmillan Publishers Ltd. ...
Europe PMC Funders Author Manuscripts Europe PMC Funders Author Manuscripts and Campbell
Page 21
Nat Rev Genet. Author manuscript; available in PMC 2013 May 29. ...
doi:10.1038/nrg3317
pmid:23044827
pmcid:PMC3666082
fatcat:ecynvhbvorb7pe6wqq52sliexi
Mnt modulates Myc-driven lymphomagenesis
2017
Cell Death and Differentiation
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The transcriptional represser Mnt is a functional antagonist of the proto-oncoprotein Myc. Both Mnt and Myc utilise Max as an obligate partner for DNA binding, and Myc/Max and Mnt/Max complexes compete for occupancy at E-box DNA sequences in promoter regions. We have previously shown in transgenic mouse models that the phenotype and kinetics of onset of haemopoietic tumours varies with the level of Myc expression. We reasoned that a decrease in the level of Mnt would increase the functional
doi:10.1038/cdd.2017.131
pmid:28800127
pmcid:PMC5686348
fatcat:elk7fqf7fvgsbi43uidsbvvwe4
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... l of Myc and accelerate Myc-driven tumorigenesis. We tested the impact of reduced Mnt in three models of myc transgenic mice and in p53 +/ − mice. To our surprise, mnt heterozygosity actually slowed Myc-driven tumorigenesis in vavP-MYC10 and Eμ-myc mice, suggesting that Mnt facilitates Myc-driven oncogenesis. To explore the underlying cause of the delay in tumour development, we enumerated Myc-driven cell populations in healthy young vavP-MYC10 and Eμ-myc mice, expecting that the reduced rate of leukaemogenesis in mnt heterozygous mice would be reflected in a reduced number of preleukaemic cells, due to increased apoptosis or reduced proliferation or both. However, no differences were apparent. Furthermore, when mnt +/+ and mnt +/ − pre-B cells from healthy young Eμ-myc mice were compared in vitro, no differences were seen in their sensitivity to apoptosis or in cell size or cell cycling. Moreover, the frequencies of apoptotic, senescent and proliferating cells were comparable in vivo in mnt +/ − and mnt +/+ Eμ-myc lymphomas. Thus, although mnt heterozygosity clearly slowed lymphomagenesis in vavP-MYC10 and Eμ-myc mice, the change(s) in cellular properties responsible for this effect remain to be identified.
Mainuddin Ahmed Archibald Cabbourn ("Bill") Boyle Alexander McCorkindale Campbell Peter Seymour Virgil Cox James Gray Denholm Eric Charles ("Buster") Glover Robert Emil Albert Saabye Hansen Jonathan ("John") James Mercer Kew Samuel Reid Campbell Ritchie William Michael Brian Strangeways Alistair James Thomson Thomas James ("Johnny") Walker
1998
BMJ (Clinical Research Edition)
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[A G M Campbell]
Peter Seymour Virgil Cox Former lecturer in public health Leeds (b Lewisham 1927; q St Thomas's 1954; MD; OBE) , died of myocardial infarction on 25 June 1998. ...
[Peter Strangeways] Alistair James Thomson Former general practitioner Birmingham (b Inverness 1911; q Otago 1937), d 9 July 1998. ...
doi:10.1136/bmj.317.7162.889
pmid:9748198
pmcid:PMC1113959
fatcat:23gduj5anrblnmr5nrun4soei4
Universal Patterns of Selection in Cancer and Somatic Tissues
2018
Cell
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Stratton, Peter J. Campbell. Quality controls and use of TCGA calls in five cancer types 2.4. Calling of copy number changes 3. ...
Dawson, Kerstin Haase, Peter Van Loo, Helen Davies, Michael R. ...
doi:10.1016/j.cell.2018.06.001
pmid:29906452
pmcid:PMC6005233
fatcat:naabqsnkebc3zdekvgrdi3wntu
All Boats Rise with the Tide
2013
Anesthesia and Analgesia
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Campbell, MD. ...
doi:10.1213/ane.0b013e318279b61b
pmid:23709070
fatcat:zjrrcaknf5cmnncq35udt6oszy
Criteria for Inference of Chromothripsis in Cancer Genomes
2013
Cell
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Marked differences in the spatial distribution, number, and types of somatically acquired DNA rearrangements observed between cancer entities (Yates and Campbell, 2012) , however, limit the utility of ...
Read-depth analysis (Campbell et al., 2008; Chiang et al., 2009) , an approach based on identifying copy-number alterations by analyzing the DNA read depth of coverage, can also be used to discover structural ...
doi:10.1016/j.cell.2013.02.023
pmid:23498933
fatcat:vzqzngmnzfbdlcilhnxnmuahui
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