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The Sars-Cov-2 Pandemic and the Brave New Digital World of Environmental Enrichment to Prevent Brain Aging and Cognitive Decline
2020
The journal of prevention of Alzheimer's disease
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The evolving, highly contagious global viral spread has created a pressure test of unprecedented proportions for the existing brain health care infrastructure and related services for management, diagnosis ...
Social distancing and lock-down measures are catalyzing and accelerating a technological paradigm shift, away from a traditional model of brain healthcare focused on late symptomatic disease stages and ...
Acknowledgment: We thank Ricky Kurzman and Stephanie Cropper for their kind support in the critical revision of the article. ...
doi:10.14283/jpad.2020.39
pmid:32920634
pmcid:PMC7355512
fatcat:dik2tnxndfgjfnwoc7b2rbreia
The Perspectives Associated With the Computer-Based Diagnostic Method of Depressive Disorder
2018
Frontiers in Psychiatry
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The confirmation of this hypothesis can shed a new perspective on early contactless, computer-based psychiatric diagnostic strategies and early identification of DD symptoms, as DD is an important issue ...
for diagnosis of DD. ...
ACKNOWLEDGMENTS The authors gratefully acknowledge the Research Council of Lithuania for financial support (Project EMOPSYCHOSCREEN No. P-MIP-17-49). ...
doi:10.3389/fpsyt.2018.00687
pmid:30618867
pmcid:PMC6305725
fatcat:3lcjliu3kra2dfd65bjbvu7scy
A classifier fusion strategy to improve the early detection of neurodegenerative diseases
2015
International Journal of Artificial Intelligence and Soft Computing
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Many believe that the early detection of neurodegenerative diseases will provide a much more sustainable framework for dealing with age-related diseases in the future. ...
early detection of neurodegenerative diseases', Int. ...
The goal is to provide a sophisticated and potentially powerful tool that improves the early detection, diagnosis and treatment of neurodegenerative diseases. ...
doi:10.1504/ijaisc.2015.067525
fatcat:kdj3zz2y2rekhdvwyxflmax454
Application of Precision Medicine in Neurodegenerative Diseases
2018
Frontiers in Neurology
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One of the main challenges for healthcare systems is the increasing prevalence of neurodegenerative pathologies together with the rapidly aging populations. ...
In fact, the availability of high technology and computational facilities for large-scale analysis enabled a deeper investigation of neurodegenerative disorders, providing a more comprehensive overview ...
Currently, scientific research can rely on the availability of high-technology and computational tools for large-scale analysis. ...
doi:10.3389/fneur.2018.00701
pmid:30190701
pmcid:PMC6115491
fatcat:2vqbjhvpqjf3zeh5xpa4mu5qzu
A Precision Medicine Initiative for Alzheimer's disease: the road ahead to biomarker-guided integrative disease modeling
2017
Climacteric
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A patent in vitro procedure for diagnosis and early diagnosis of neurodegenerative diseases.
FIGURE CAPTIONS Figure 1 . ...
A patent In vitro Procedure for Diagnosis and Early Diagnosis of Neurodegenerative Diseases. Publication number: 20090263822 Issued. ...
doi:10.1080/13697137.2017.1287866
pmid:28286989
fatcat:5bdwpvg4jbej7ba3tkmrqw3keq
An early diagnosis is not the same as a timely diagnosis of Parkinson's disease
2018
F1000Research
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Benefits of early diagnosis and treatment would affect not only the individual (and their families) but also the wider society and the research community. ...
However, picking the right point for a "timely" diagnosis will vary depending on the preferences of the individual patient, efficacy (or existence) of disease-modifying treatment, and the ability for health ...
From a scientific perspective, "early" is easy to comprehend within the framework of disease pathology and its manifestations. ...
doi:10.12688/f1000research.14528.1
pmid:30079229
pmcid:PMC6053699
fatcat:tirhtpwhsjdwbb42uu364hb5aq
Gait analysis for early neurodegenerative diseases classification through the Kinematic Theory of Rapid Human Movements
2020
IEEE Access
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Up to now, some Computer Aided Diagnosis (CAD) tools for neurodegenerative assessment, have shown to be effective. Those tools are based on behavioral biometrics [1] . ...
NEURODEGENERATIVE DISEASES MOTOR PATTERNS Neurodegenerative diseases affect long neuronal cells. The affected cells create physical disorder during the walk. ...
Conflict of interest: The authors declare no conflict of interest. ...
doi:10.1109/access.2020.3032202
fatcat:pysqtp3q6zcapkpcsccpdtfhzq
Neuropsychiatric symptoms as early manifestations of emergent dementia: Provisional diagnostic criteria for mild behavioral impairment
2016
Alzheimer's & Dementia
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NPS in MCI confer a greater risk for conversion to dementia ...
Acknowledgments The authors acknowledge The Alzheimer's Association ISTAART group for reading and supporting these criteria. ...
Interpretation: Neuropsychiatric symptoms (NPS) can manifest early in the course of neurodegenerative illness. Currently, diagnosis of neurodegenerative disease is predicated on cognitive impairment. ...
doi:10.1016/j.jalz.2015.05.017
pmid:26096665
pmcid:PMC4684483
fatcat:t4om6lzegvf4zodluauyrpzmlu
A report from the 8th Kuopio Alzheimer Symposium
2018
Neurodegenerative Disease Management
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and comorbidities and novel approaches 25 for diagnosis, prediction, prevention and therapies of Alzheimer s disease (AD) and other 26 neurodegenerative diseases. ...
21 The international Kuopio Alzheimer Symposium was organized by the University of Eastern Finland 22 in Kuopio, Finland on June 6-8, 2018 for the 8 th time. ...
for 333 diagnosis of MCI and AD, e.g. by using the PredictND clinical decision support system, and taking 334 into account patients' perspective and wishes on their use. ...
doi:10.2217/nmt-2018-0029
pmid:30112972
fatcat:qrbw2lppgvevrlpbhcnszvd6fq
When dementia progresses quickly: a practical approach to the diagnosis and management of rapidly progressive dementia
2014
Neurodegenerative Disease Management
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The causes of RPD are diverse, spanning the spectrum of primary and secondary neurological diseases. ...
Causes of rapidly progressive dementia (RPD) are distinguished by the evolution of symptoms and signs over a number of days, weeks or months. ...
rate of disease of progression on the differential diagnosis, and the possibility that symptoms may represent limbic encephalitis. ...
doi:10.2217/nmt.13.75
pmid:24640978
fatcat:riiyjtndzfhrjeino5cz35pm2e
Perspectives on the modeling of the neuromusculoskeletal system to investigate the influence of neurodegenerative diseases on sensorimotor control
2018
Research on Biomedical Engineering
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that they can be useful in the future to discover early predictors of neurodegenerative diseases, as well as to propose new quantitative clinical neurophysiology approaches to follow the course of improvements ...
Albeit some efforts have been made to investigate how neurodegenerative diseases alter the dynamics of individual elements of the neuromuscular system, such diseases have not been analyzed from a systems ...
RNW was funded by FAPESP and CAPES (Coordination for the Improvement of Higher Education Personnel, proc. no. 2015/21819-3). AFK was funded by CNPq (proc. no. 303809/2016-7). ...
doi:10.1590/2446-4740.00118
fatcat:jmnn6fcoinbudow3wr5tlge5sy
Psychological and Cognitive Markers of Behavioral Variant Frontotemporal Dementia–A Clinical Neuropsychologist's View on Diagnostic Criteria and Beyond
2019
Frontiers in Neurology
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Since the histopathology of the disease is heterogeneous and identified genetic mutations only account for ~30% of cases, there are no reliable biomarkers for the diagnosis of bvFTD available in clinical ...
Early detection of bvFTD thus relies on correct application of clinical diagnostic criteria. ...
FUNDING We acknowledge support from the Open Access Publication Fund of the University of Muenster. ...
doi:10.3389/fneur.2019.00594
pmid:31231305
pmcid:PMC6568027
fatcat:bu65bvxpkzenrgifwqiiphq2ye
Clinical impact and diagnostic accuracy of 2-[18F]-fluoro-2-deoxy-d-glucose positron-emission tomography/computed tomography (PET/CT) brain imaging in patients with cognitive impairment: a tertiary centre experience in the UK
2017
Clinical Radiology
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, small reductions in metabolic activity in the hippocampus are not usually 201 demonstrable on FDG PET in the early stages of the AD [13]. 202 203
brain perfusion single-photon emission computed tomography ...
Discussion
162 The diagnosis of dementia can be challenging, especially in the early stages of the disease, in 163 younger patients (<65 years), in those with atypical presentations, and in patients ...
doi:10.1016/j.crad.2016.08.003
pmid:27637430
fatcat:wuvcuhqnmbenpbiu6et4medasu
Global Current Trends in Drug Designing for Management of Type-2 Diabetes and Neurodegenerative Disorders
2013
Drug Designing: Open Access
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Neurodegenerative diseases (NDs) and Type 2 diabetes (T2D) are progressive disorder often advances with age. ...
Since conventional drugs fail to surpass the natural CNS protective barriers, therefore, in order to overcome these hurdles, targeted drug delivery is of foremost significance for the treatment of AD and ...
Gazdar, Librarian, and KFMRC for providing assistance in retrieving research articles from journals available in the library and as well from different web resources. ...
doi:10.4172/2169-0138.1000e120
fatcat:um4hqmpndvarjht5jtatcmleam
Mild Behavioral Impairment: presentation of the diagnostic criteria and the Italian version of the MBI-Checklist
2019
Rivista di psichiatria
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For some, MBI may be the initial manifestation of neurodegenerative disease, observed before cognitive impairment is apparent. ...
The need to identify, in the early stages of the disease, the population at risk of cognitive decline has led to the formulation of the concept of Mild Behavioral Impairment (MBI). ...
The identification of a population at risk for neurodegenerative disease has important implications on the therapeutic management of affective, psychotic and behavioral symptoms and on the prevention of ...
doi:10.1708/3142.31246
pmid:30985830
fatcat:ls7hiunx2jgyplak237ro4tafy
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