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The de novo FAIRification process of a registry for vascular anomalies

Karlijn H. J. Groenen, Annika Jacobsen, Martijn G. Kersloot, Bruna dos Santos Vieira, Esther van Enckevort, Rajaram Kaliyaperumal, Derk L. Arts, Peter A. C. 't Hoen, Ronald Cornet, Marco Roos, Leo Schultze Kool
2021 Orphanet Journal of Rare Diseases  
This includes the creation of an electronic case report form and a semantic data model of the elements to be collected (in this case: the "Set of Common Data Elements for Rare Disease Registration" released  ...  by the European Commission), and the technical implementation of automatic, real-time data FAIRification in an Electronic Data Capture system.  ...  Acknowledgements We thank Maria Barea for her input as a patient advocate and Mark D. Wilkinson for his input on the FAIR data principles.  ... 
doi:10.1186/s13023-021-02004-y pmid:34481493 fatcat:bnqumiyarjghrgrd7vgegestxi

Meeting abstracts from the 4th International Clinical Trials Methodology Conference (ICTMC) and the 38th Annual Meeting of the Society for Clinical Trials

2017 Trials  
Acknowledgements With special thanks to the Bowel Disease Research Foundation.  ...  Acknowledgements Funded by the MRC North West Hub in Trials Methodological Research (MR/K025635/1) and the NIHR Health Technology Assessment programme (08/14/39).  ...  This necessitated development of a solution to automatically monitor electronic case report form (ECRF) completion and track timely completion of ECRFs.  ... 
doi:10.1186/s13063-017-1902-y fatcat:yt477zyq4vbi7cm6f3sozyl42u

An intensified dosing schedule of subcutaneous methotrexate in patients with moderate to severe plaque-type psoriasis (METOP): a 52 week, multicentre, randomised, double-blind, placebo-controlled, phase 3 trial

Richard B Warren, Ulrich Mrowietz, Ralph von Kiedrowski, Johannes Niesmann, Dagmar Wilsmann-Theis, Kamran Ghoreschi, Ina Zschocke, Thomas M Falk, Norbert Blödorn-Schlicht, Kristian Reich
2017 The Lancet  
The trial was performed in a double-blind manner from the time of randomisation until an interim database lock for the data up to and including week 16.  ...  Participants were randomly assigned 3:1 by computer-generated random sequence integrated in the electronic data capture system to receive either MTX at a starting dose of 17.5 mg/week or placebo for the  ...  Participants were randomly assigned 3:1 by computer-generated random sequence integrated in the electronic data capture system to receive either MTX at a starting dose of 17.5 mg/week or placebo for the  ... 
doi:10.1016/s0140-6736(16)32127-4 pmid:28012564 fatcat:27lyo3bnkzeghd2d4futsnx7bu

57th Annual ORCA Congress

2010 Caries Research  
The abstracts are available free online at www.karger.com/doi/10.1159/000315447  ...  The conduct of a meta-analysis involves the careful application of a strict protocol in order to ensure the validity of the results.  ...  Firstly, the dentists were randomly assigned to start data capture either with the Paper Case Report Form (PCRF) or the Electronic Case Report Form (ECRF).  ... 
doi:10.1159/000315447 fatcat:tg63pzlb2zdgzm4ehjrsdc65yy

Poster Abstracts

2021 Fundamental & Clinical Pharmacology  
PS-176 | Comparison of a semi-automated meta-analysis versus conventional meta-analysis: A study protocol P. Ajiji 1 ; J. Cottin 2 ; E. Ripoche 3 ; M. Cucherat 2 ; P.  ...  Trim and fill: A simple funnelplot-based method of testing and adjusting for publication bias in meta-analysis. Biometrics. (2000) 56 455-63.  ...  Material and methods: Medical transmissions from interns to senior pharmacologists reported during one year were recorded on an electronic spreadsheet.  ... 
doi:10.1111/fcp.12670 fatcat:apbtlbx4yrdstk2uunnxeysfoa

Oral Abstracts

2013 Fundamental & Clinical Pharmacology  
Prevention of ventilatorassociated pneumonia with oral antiseptics: a systematic review and meta-analysis. Lancet Infect. Dis. (2011) 11 845-854.  ...  However, transcriptome analysis revealed upregulation of TAS2R signaling in peripheral blood leucocytes from patients with severe asthma, as well as a correlation between clinical markers of asthma severity  ...  Scanning electron microscope (SEM) analysis was performed in 26 stones from the green tea group and 31 stones from controls, all selected for a high weddellite content.  ... 
doi:10.1111/fcp.12025 pmid:23614855 fatcat:hiajqjvj3na27gs42r4nfrbdl4

Continuing Progress in Vasculitis Research. Abstracts of the 17th International Vasculitis & ANCA WorkshopLondon, April 19-22, 2015: Abstracts

2015 Nephron  
Genotyping data were subjected to rigorous quality control measures and subsequently analyzed to discover genetic susceptibility loci for Takayasu's arteritis.  ...  Objective: Takayasu's arteritis is a rare large vessel vasculitis with incompletely understood etiology. We performed the first genome-wide association study (GWAS) in Takayasu's arteritis.  ...  Data was collected retrospectively from patient's medical records, and electronic secondary care records.  ... 
doi:10.1159/000381121 pmid:25895550 fatcat:orlgym6k4ngoha2qp36jyhlnau

I2ECR: Integrated and Intelligent Environment for Clinical Research [article]

GIAN MARIA ZACCARIA
2018
to the security of personal data.  ...  To verify whether DWs might be useful for data quality and association analysis, a team of biomedical engineers, clinicians, biologists and statisticians developed the "I2ECR" project.  ...  I2ECR allows to monitor, in a semi-automatic manner, the quality of data, in relation to the clinical data imported from eCRFs (electronic Case Report Forms) and from biologic and mutational datasets internally  ... 
doi:10.6092/polito/porto/2707999 fatcat:s7ekusqwgfdnlpzh3e4zcc6qny

Abstracts DEGRO 2018

2018 Strahlentherapie und Onkologie (Print)  
So bringen u . a . die Erfolge auf dem Gebiet der Tumormolekulargenetik zwangsläufig immer komplexere Entscheidungspfade und somit eine weitere Individualisierung der Behandlungen mit sich, der sich Ärzte  ...  Patient and disease data was collected anonymously via electronic case report forms (eCRF) and entered into the multi-institutional "Radplan-Bio" platform for central data analysis .  ...  Methods: From a contemporary cohort of 43 patients with paragangliomas of the head and neck, 22 were suitable for volumetric analysis .  ... 
doi:10.1007/s00066-018-1301-7 pmid:29777265 fatcat:3gtq3dpopzc7pmpc5vrouo43yu

Supplementum 222: Joint annual meeting Swiss Society of Paediatrics and the Swiss Society for Allergology and Immunology, jointly organized with the 4th Lymphoid Tissue Meeting "Focus on Stromal Cells"

2017 Swiss Medical Weekly  
We investigated the ability of human LNSCs derived from RA, RA-risk and healthy individuals to sense and respond to pathogens.  ...  Results: 394 of 476 children (83%) provided valid PA data (at least 2 week-and 1 weekend-day with 10h recording; mean age 3.9 ± 0.7 years, 54% boys) with 26% and 74% living in the French-and German-2 Department  ...  Data are recorded in a REDCap database.  ... 
doi:10.4414/smw.2017.20424 pmid:33379860 fatcat:bpqm632nhffkjhzwtlemyopusa

Clinical and functional consequences of energy provided by nutrition in critically ill adults

EMMA JEAN RIDLEY
2018
One of the primary aims is to ensure they receive enough energy to support their recovery, however there are many reasons why this does not occur.  ...  This thesis aims to investigate current practice in delivery of nutrition in Australia and New Zealand, test a strategy to provide additional energy within intensive care, and determine what happens to  ...  We commend the authors for attempting to answer this question with what appears to be a methodologically robust meta-analysis; however, we don't believe the study selection criteria for the full-feeding  ... 
doi:10.26180/5b4c45e039c74 fatcat:4ci4cokczjgk5mzdz3mz4bw7iy

Rehabilitation of Stroke Patients with Sensor-based Systems

Jeremia Held
2019
Acknowledgements The authors would like to thank Mark van Raai for his help in the implementation of the ArmeoSenso software, and Irene Christen, Jose Lopez and Belen Valladares for their support with  ...  referenceS Acknowledgements The authors would like to thank Dr. Viktoria Kluckner, Joachim Cerny and Elisabeth Sandner for their support with the study. Acknowledgements Acknowledgements  ...  All patients will receive a reminder for each visit to diminish retention and incomplete follow-up. data management Study data will be recorded in electronic Case Report Forms (eCRF).  ... 
doi:10.5167/uzh-186343 fatcat:xzgo22hg3bgond4vh5jnq4l7eu

Targeting the oxytocin system to treat opioid dependence - mental health comorbidity

Carol D Weber
2019
This thesis also provides a reflective analysis on the difficulties in recruiting and working with vulnerable participants as well as the challenges of setting up and running a clinical trial of an investigative  ...  Given the emergence of preclinical and clinical data showing anti-addictive properties of neuropeptide oxytocin, a randomised double-blind placebo-controlled pilot trial was performed to investigate the  ...  f We will aim to see patients and conduct the questionnaire tests in person but if that is not possible then we will resort in telephone contact.  ... 
doi:10.15126/thesis.00852346 fatcat:vdpl7m5t3bhppbe4t6uvrygdum

Disfunzioni della Percezione Corporea nelle Patologie Muscoloscheletriche e Reumatiche [article]

ANTONELLO VICECONTI
2020
APPENDIX II In this Appendix, it has been reported the protocol of Scoping Declaration of conflicting interests The author(s) declared no potential conflicts of interest with respect to the research  ...  Funding The author(s) received no financial support for the research, authorship, and/or publication of this article.  ...  A second author (DP) performed the crosschecking of data extracted. Information extracted from each study are detailed in Supplementary Files of the published study protocol.  ... 
doi:10.15167/viceconti-antonello_phd2020-05-26 fatcat:upmv2pg6hzgz5bkuwkitswzybe

Multifold aspects of obesity and insulin resistance: comorbidities and crosstalk with thyroid gland

CHIARA MELE
2018
/mL and the analysis was automatically performed using ADVIA Ce tau ATPO "ie e s Health a e Diag osti i ., Ta to , NY, U"A Age at diagnosis in groups A and B.  ...  A meta-analysis of 13 randomized controlled trials with >90,000 participants found a 9% risk for incident NOD after 4 years of statin treatment, particularly in those who were older (Sattar 2010) and on  ... 
doi:10.20373/uniupo/openthesis/102829 fatcat:lt64rym7erdc5jg3cx73zzoq6u