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Characterization and regional distribution of nitric oxide synthase in the human brain during normal ageing

Doris Blum-Degen, Thoralf Heinemann, Jing Lan, Vera Pedersen, Fritz Leblhuber, Werner Paulus, Peter Riederer, Manfred Gerlach
1999 Brain Research  
Nowadays, many process aware information systems are implemented (e.g., workflow management systems) and business processes are evaluated and redesigned.  ...  An important part of the evaluation of designed and redesigned business processes is Business Process Simulation (BPS).  ...  Acknowledgement This research is supported by the Technology Foundation STW, applied science division of NWO and the technology programme of the Dutch Ministry of Economic Affairs.  ... 
doi:10.1016/s0006-8993(99)01444-4 pmid:10407101 fatcat:nxzvq3wkafcsbnai6ntvqw5pau

Process Mining Contributions to Discrete-event Simulation Modelling

Mario Jadrić, Ivana Ninčević Pašalić, Maja Ćukušić
2020 Business Systems Research  
as an input for discrete-event simulation modelling, using two different datasets, one of which is considered data-poor while the other one data-rich.Methods/Approach: Statistical calculations and process  ...  topics that could be tackled and supported by the new combined approach.Conclusions: Event logs and process mining provide valuable information and techniques that could be a useful input for simulation  ...  To discrete-event modelling process, event logs and process mining can provide valuable information and techniques that could be used for simulation modelling, especially in the first steps of building  ... 
doi:10.2478/bsrj-2020-0015 fatcat:a35ebqq5sfaz7hulz6mrr6rv5m

A process-oriented methodology for evaluating the impact of IT: A proposal and an application in healthcare

Ronny Mans, Hajo Reijers, Daniel Wismeijer, Michiel van Genuchten
2013 Information Systems  
Using discrete event simulation, a model can be build which accurately mimics the discovered process and which can subsequently be used for exploring and evaluating various redesign of the same process  ...  In our method, process mining and discrete event simulation are key ingredients.  ...  Acknowledgement This project was supported by a grant from the ITI foundation for the Promotion of Oral Implantology, Switzerland.  ... 
doi:10.1016/j.is.2013.06.005 fatcat:sd7nct3fmbct7cevag7vhplobu

From Advanced Planning System to Advanced Budgeting System: The Next Step in Supply Chain Management Software [chapter]

Pierre Fenies, Nikolay Tchernev
2012 Pathways to Supply Chain Excellence  
The specification of supply chain running thanks to ARIS modelling is translated in discrete event simulation computer model ( figure 6 ).  ...  This financial computer model is done and linked to Discrete Event Simulation Model with Visual Basic.  ...  The coverage focuses on how to build a competitive supply chain using viable management strategies, operational models, and information technology.  ... 
doi:10.5772/32967 fatcat:hu4b2rukobaflb25lidajzrmgu

On the role of data, statistics and decisions in a pandemic [article]

Beate Jahn, Sarah Friedrich, Joachim Behnke, Joachim Engel, Ursula Garczarek, Ralf Münnich, Markus Pauly, Adalbert Wilhelm, Olaf Wolkenhauer, Markus Zwick, Uwe Siebert, Tim Friede
2022 arXiv   pre-print
The process of decision-making starts with data collection and modeling and continues to the dissemination of results and the subsequent decisions taken.  ...  A special focus is on the role played by data in these different models, and we incorporate into the discussion the importance of statistical literacy, and of effective dissemination and communication  ...  Chan School of Public Health) for proofreading and language editing.  ... 
arXiv:2108.04068v2 fatcat:h4gueufzqjezfe5qsmjjzudnqm

Analysis of the interventions adopted due to the COVID-19 on ARI morbility for Colombia [article]

Alvaro Quijano-Angarita, Oscar Espinosa, Marcela M Mercado-Reyes, Diana Walteros, Diana Carolina Malo
2020 medRxiv   pre-print
Acute Respiratory Infections are among the leading causes of death globally, particularly in developing countries, and are highly correlated with the quality of health and surveillance systems and effective  ...  The objective of this document is the application of a flexible model for the identification of the pattern and monitoring of ARI morbility for Colombia by age group that shows atypical patterns in the  ...  The model was fitted using JAGS, simulating 3 chains of 30,000 draws each with a burning period 117 of 15,000.  ... 
doi:10.1101/2020.09.12.20193334 fatcat:7cieiftifnfxdflov473aku474

Parallel and distributed discrete event simulation

Richard M. Fujimoto
1993 Proceedings of the 25th conference on Winter simulation - WSC '93  
This tutorial reviews issues concerning the execution of discrete event simulation programs on multiprocessor and distributed computing platforms.  ...  The synchronization problem that has driven much of the research in this field is reviewed. Space-parallel and  ...  [Baezner et al., 1993] simulate a health care system consisting of a hierarchical net- work of hospitals.  ... 
doi:10.1145/256563.256596 dblp:conf/wsc/Fujimoto93 fatcat:wtv7z2clnna37mznyxxno75kha

Simulation modelling in healthcare: reviewing legacies and investigating futures

T Eldabi, R J Paul, T Young
2007 Journal of the Operational Research Society  
Towards incorporating human behaviour in models of health care systems: an approach using discrete event simulation. Eur J Opl Res 150(1): 19-31.  ...  By simulation, we are referring to the widest possible range of simulation and modelling techniques, from spreadsheets to discrete event simulation and system dynamics.  ... 
doi:10.1057/palgrave.jors.2602222 fatcat:2lslpyegubatjj6johk5z7jktq

Assessment of E-Business Transformation Using Simulation Modeling

Vesna Bosilj-Vuksic, Mojca Indihar Stemberger, Jurij Jaklic, Andrej Kovacic
2002 Simulation (San Diego, Calif.)  
system performance.  ...  An example is presented of how simulation modeling can be used to understand a procurement process and evaluate how the proposed improvements and the introduction of electronic business will influence  ...  Business process modeling was conducted using discrete event simulation (petri nets).  ... 
doi:10.1177/0037549702078012003 fatcat:pqiwuihl3fbmhnsfj6wlx4joaq

Web Technologies and Multi-criterion Analysis used in Enterprise Integration

Marius CIOCA, Lucian – Ionel CIOCA, Luminiţa DUŢĂ
2011 Studies in Informatics and Control  
These [11] are graphical and mathematical tools for representing and analyzing discrete event systems, characterized by parallelism and synchronization.  ...  Modeling enterprises by Abstract: The studies, research and solutions presented below started from the acute need of small and medium-sized enterprises to integrate their processes, services and relationships  ...  ARIS performs a detailed description of an enterprise in terms of data model, functional, organizational and process models, as well as from the perspective of model analysis, it is an indispensable requirement  ... 
doi:10.24846/v20i2y201105 fatcat:ztbpohuayneivfwa2csi4zyvui

Hospital Registration Process Reengineering Using Simulation Method

Qiang Su, Xiaoyun Yao, Ping Su, Jinghua Shi, Yan Zhu, Lei Xue
2010 Journal of Healthcare Engineering  
Furthermore, through a series of simulation experiments, the length of the prepare queue and the corresponding registration process efficiency was quantitatively evaluated and optimized.  ...  Guided by the principle of business process reengineering (BPR), a simulation approach was employed for process redesign and performance optimization.  ...  Wang et al. resolved the overlong waiting time in emergency services using modeling and discrete event simulation with software systems of ARIS and Arena [17] .  ... 
doi:10.1260/2040-2295.1.1.67 fatcat:2fevu7hkzrhvfol77fmxtwv3ki

BREM-SC: A Bayesian Random Effects Mixture Model for Joint Clustering Single Cell Multi-omics Data [article]

Xinjun Wang, Zhe Sun, Yanfu Zhang, Zhongli Xu, Heng Huang, Richard H Duerr, Kong Chen, Ying Ding, Wei Chen
2020 bioRxiv   pre-print
Through simulation studies and analysis of public and in-house real data sets, we successfully demonstrated the validity and advantages of this method in fully utilizing both types of data to accurately  ...  More recently, coupled with the cutting-edge Cellular Indexing of Transcriptomes and Epitopes by Sequencing (CITE-seq), the droplet-based system has allowed for immunophenotyping of single cells based  ...  ., 10X Genomics Chromium system (4) ) and utilizes the discrete count of Antibody-Derived Tags (ADT) as the direct measurement of cell surface protein abundance.  ... 
doi:10.1101/2020.01.18.911461 fatcat:ukv4tgo7ezbhtdyr5h7bg5lb4y

Discrete event modelling for evaluation and optimisation of power utility energy demand

Megashnee Munsamy, Arnesh Telukdarie
2022 Journal of Industrial Engineering and Management  
research adopts a quantitative approach focusing on Discrete Event Modeling.  ...  simulated to evaluate the baseline electrical energy demand and associated CO2 emissions.  ...  The model delivered, together with associated results proves that business process models can be adopted for energy predictability and optimisation.  ... 
doi:10.3926/jiem.3606 fatcat:ftvx7wzu35ae5ge3pq5lbr5guu

Auto-Regressive Integrated Moving-Average Machine Learning for Damage Identification of Steel Frames

Yuqing Gao, Khalid M. Mosalam, Yueshi Chen, Wei Wang, Yiyi Chen
2021 Applied Sciences  
Auto-regressive (AR) time series (TS) models are useful for structural damage detection in vibration-based structural health monitoring (SHM).  ...  The confusion matrix results showed the unbiased model performance even under an imbalanced-class distribution.  ...  These average AIC values evaluate the overall fitting performance of each candidate model.  ... 
doi:10.3390/app11136084 fatcat:xeo7s2a7uzcmlklccr72gqx5qa

A systematic review of studies on forecasting the dynamics of influenza outbreaks

Elaine O. Nsoesie, John S. Brownstein, Naren Ramakrishnan, Madhav V. Marathe
2013 Influenza and Other Respiratory Viruses  
Your story matters Citation Nsoesie, Elaine O, John S Brownstein, Naren Ramakrishnan, and Madhav V Marathe. 2013. "A systematic review of studies on forecasting the dynamics of influenza outbreaks."  ...  Influenza and Other Respiratory Viruses 8 (3): 309-316.  ...  , of IARPA, DoI/NBC, or the US Government.  ... 
doi:10.1111/irv.12226 pmid:24373466 pmcid:PMC4181479 fatcat:dmqavzp6kbcd7b6pewoxcl6vmq
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