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Partial Volume Correction in Arterial Spin Labeling Perfusion MRI: A method to disentangle anatomy from physiology or an analysis step too far?

Michael A. Chappell, Flora A. Kennedy McConnell, Xavier Golay, Matthias Günther, Juan A. Hernandez-Tamames, Matthias J. van Osch, Iris Asllani
2021 NeuroImage  
The mismatch in the spatial resolution of Arterial Spin Labeling (ASL) MRI perfusion images and the anatomy of functionally distinct tissues in the brain leads to a partial volume effect (PVE), which in  ...  turn confounds the estimation of perfusion to a specific tissue of interest such as grey or white matter.  ...  MC The data used in this work for Fig. 2 were obtained from UK Biobank Resource under Application Number 43172.  ... 
doi:10.1016/j.neuroimage.2021.118236 pmid:34091034 fatcat:el4orqrjgrdvnpiextmqec2bfq

École de Physique des Houches [chapter]

2006 Les Houches  
Established in 1951, the Physics School is located in a group of chalets surrounded by meadows and woods, at an altitude of 1150 m facing the Mont-Blanc range -a very favourable environment for intellectual  ...  activity in ideal surroundings for skiing, hiking or mountaineering.  ...  ., and Schmittbuhl, M. (2008) correlaTive analysis of recurrenT MulTicolor fluorescence iMaGes To characTerize in vivo The effecT of anTiveGf druGs on GlioBlasToMa TuMor develoPMenT Rodriguez, T.  ... 
doi:10.1016/s0924-8099(06)80084-3 fatcat:6w7diik2k5af7cpowh4xz3nsky

ÉCole De Physique Des Houches [chapter]

2007 Les Houches  
Established in 1951, the Physics School is located in a group of chalets surrounded by meadows and woods, at an altitude of 1150 m facing the Mont-Blanc range -a very favourable environment for intellectual  ...  activity in ideal surroundings for skiing, hiking or mountaineering.  ...  ., and Schmittbuhl, M. (2008) correlaTive analysis of recurrenT MulTicolor fluorescence iMaGes To characTerize in vivo The effecT of anTiveGf druGs on GlioBlasToMa TuMor develoPMenT Rodriguez, T.  ... 
doi:10.1016/s0924-8099(13)60020-7 fatcat:jydcwidbbnf3nppqp4x3pyu6ga

École de Physique des Houches [chapter]

2008 Les Houches  
Established in 1951, the Physics School is located in a group of chalets surrounded by meadows and woods, at an altitude of 1150 m facing the Mont-Blanc range -a very favourable environment for intellectual  ...  activity in ideal surroundings for skiing, hiking or mountaineering.  ...  ., and Schmittbuhl, M. (2008) correlaTive analysis of recurrenT MulTicolor fluorescence iMaGes To characTerize in vivo The effecT of anTiveGf druGs on GlioBlasToMa TuMor develoPMenT Rodriguez, T.  ... 
doi:10.1016/s0924-8099(13)60004-9 fatcat:nxiezedqabbbtnfqonvw6c3doi

Pitfalls in fMRI

Sven Haller, Andreas J. Bartsch
2009 European Radiology  
The by far most influential fMRI technique is based on a local T2*-sensitive hemodynamic response to neuronal activation, also known as the blood oxygenation level dependent or BOLD effect.  ...  We review some essential processes and assumptions of BOLD fMRI and discuss related confounds and pitfalls in fMRIfrom the underlying physiological effect, to data acquisition, data analysis and the interpretation  ...  Preibisch C, Haase A (2001) Perfusion imaging using spin-labeling methods: contrast-to-noise comparison in functional MRI applications. Magn Reson Med 1:172-182 30.  ... 
doi:10.1007/s00330-009-1456-9 pmid:19504107 fatcat:dnd7t5ite5dj3fjm7rlm4hi2dm

Cortical laminar resting‐state signal fluctuations scale with the hypercapnic blood oxygenation level‐dependent response

Maria Guidi, Laurentius Huber, Leonie Lampe, Alberto Merola, Kristin Ihle, Harald E. Möller
2020 Human Brain Mapping  
This is achieved by scaling, using information from a perfusion-sensitive scan during a purely vascular challenge, typically induced by a gas manipulation or a breath-hold task.  ...  In this work, we seek for a validation of the use of the resting-state fluctuation amplitude (RSFA) as a scaling factor to remove vascular contributions from the BOLD response.  ...  Finally, the additionally required functional contrast, such as CBF recorded with arterial spin labeling (ASL) (Alsop et al., 2015; Detre, Leigh, Williams, & Koretsky, 1992; Lorenz, Mildner, Schlumm,  ... 
doi:10.1002/hbm.24926 pmid:31957959 fatcat:sl3thtwzi5aynkpnx35n6rxqsm

15. Deutscher Wirbelsäulenkongress

2020 European spine journal  
for partial volume effects.  ...  Disentangling micro from mesostructure by diffusion MRI: A Bayesian approach. NeuroImage 2017.  ...  They have got a deformity surgery either by posterior correction spondylodesis or by anterior derotationspondylodesis. In all cases surgery was performed by the same surgeon.  ... 
doi:10.1007/s00586-020-06630-1 pmid:33078266 fatcat:2e63m5xi7zfmrjjoxffwn5pq5m

Endovascular Treatment of Dural Carotid Cavernous Sinus Fistulas

Ajay K Wakhloo
2009 Journal of neuro-ophthalmology  
A. Pirbhai.  ...  Some of the anatomy and physiology text seemed out of place except in a reference for beginning residents, which just adds volume to an already voluminous book.  ...  The method chosen in a given patient depends on the anatomy of the fistula and operator or institutional preference.  ... 
doi:10.1097/wno.0b013e31819d5669 pmid:19458566 fatcat:sgq7x6kyi5ci3iqdribu6wksvu

3rd International Congress on Neurology and Epidemiology. Abu Dhabi, UAE, November 21–23, 2013: Abstracts

2013 Neuroepidemiology  
Cerebral blood flow (CBF) was measured using the pseudo continuous arterial spin labeling (pCASL), an MRI based noninvasive technique, both in MS patients and normal controls.  ...  In some cases a referral to a specialist may be needed to differentiate it from a serious condition like epilepsy or to recommend an appropriate drug therapy.  ...  In 2 instances (2.3%) the position of one of the skull fiducials turned out to be too close to the skull mounted device resulting in dropping this fiducial from the registration.  ... 
doi:10.1159/000356326 fatcat:cwvmef3j4bgbxctcrlbsfml4da

Poster Session II

2005 Neuropsychopharmacology  
Methods: Eighteen cocaine dependent subjects and 18 healthy controls underwent full brain Diffusion tensor imaging (DTI) acquired with a diffusion sensitized dual spin echo prepared echoplanar imaging  ...  The distortion corrected images were decoded using a least squares singular value decomposition approach to estimate the diffusion tensor elements.  ...  Schizophrenia is Associated with Increased Synaptic Dopamine in Associative Rather than Limbic Regions of the Striatum Marc Laruelle*, Lawrence S Kegeles, Gordon W Frankle, Raj Narendran, Roberto Gil,  ... 
doi:10.1038/sj.npp.1300970 fatcat:ikayo4dkwrdrthgopr2hltn2hi

Concurrent TMS-fMRI for causal network perturbation and proof of target engagement

Til Ole Bergmann, Rathiga Varatheeswaran, Colleen A Hanlon, Kristoffer H Madsen, Axel Thielscher, Hartwig Roman Siebner
2021 NeuroImage  
We will also discuss how concurrent TMS-fMRI during a behavioral task can help to link behavioral TMS effects to changes in neural network activity and to identify peripheral co-stimulation confounds.  ...  The purpose of this review is to introduce the reader to this powerful tool.  ...  Siebner holds a 5-year professorship in precision medicine at the Faculty of Health Sciences and Medicine, University of Copenhagen which is sponsored by the Lundbeck Foundation (Grant Nr.  ... 
doi:10.1016/j.neuroimage.2021.118093 pmid:33940146 fatcat:5jdc2wnwsff5hkt7l4abilfko4

ACNP 57th Annual Meeting: Poster Session III

2018 Neuropsychopharmacology  
Methods: We included subjects from an ongoing cohort of older adults with major depression (n = 66) that underwent 3 T brain MRI scan and comprehensive neurocognitive assessment.  ...  SASP biomarkers were derived from proteomic panel measured by multiplex immunoassay, and the SASP index was derived the regression analysis from a previously published study.  ...  MRI volumes were normalized to intracranial volume (ICV).  ... 
doi:10.1038/s41386-018-0268-5 fatcat:wiooxnisvfhovadauljiso4ie4

The effects of spike activity on measures of neural encoding

Randall Powers, Adrienne Fairhall, Marc Binder
2006 Physiology News  
M Me ee et ti in ng gs s U UC CL L I Im ma ag ge es s o of f O Ox xf fo or rd d B Br ri is st to ol l r re ev vi is si it te ed d winter 2005 | number 61 PHYSIOLOGYNEWS Also featuring: Physiology in space  ...  Richard Naftalin's 'desert island' selection Cutting through the melatonin hype Reflections of a ex-Chair Letter from Russia What turned us on to physiology Winter books special  ...  ) to Osvaldo Delbono.  ... 
doi:10.36866/pn.61.40 fatcat:cghdipgorzgzhbs7wrwd5pxptu

Panel, Mini-panel and Study Group

2014 Neuropsychopharmacology  
Methods: In a series of studies in healthy individuals and unaffected first-degree relatives of schizophrenia patients we have established and confirmed the link of these phenotypes to the genetic liability  ...  Here, much interest has been devoted to functional MRI (fMRI)-based phenotypes related to the genetic risk for the disorder; in particular, functional connectivity of the DLPFC and hippocampus during working  ...  After MRI co-registration, timeactivity curves from 23 brain regions were generated. Plasma input graphical analysis (PRGA), using HPLC metabolite corrected arterial plasma, was employed.  ... 
doi:10.1038/npp.2014.279 pmid:25466712 pmcid:PMC4261146 fatcat:v6fgkukh6zgtdmswrjpk46dvhi

4th European conference on schizophrenia research: together for better treatment and care

2013 European Archives of Psychiatry and Clinical Neuroscience  
Methods: A total of 79 subjects with schizophrenia, schizoaffective or maniac disorder (ICD-10), who have received compulsory general psychiatric hospital treatment, are to be enrolled in a prospective  ...  Methods: According to the mild encephalitis (ME) hypothesis, LLNI represents the core pathogenetic mechanism in a schizophrenia subgroup, possibly triggered by infections, autoimmunity, toxicity, or trauma  ...  Patients and controls underwent MRI scanning including diffusion tensor imaging (DTI) and arterial spin labelling.  ... 
doi:10.1007/s00406-013-0433-0 pmid:23959132 fatcat:zgntoorsxvbbppkld4nuedpfnm
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