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Results: We present a novel pattern-based probabilistic approach, PSSV, to identify somatic structural variations from WGS data. ... Large-scale identification of somatic structural variations (SVs) for a specific cancer type will deepen our understanding of driver mechanisms in cancer progression. ... Discussion A pattern based probabilistic model (PSSV) has been developed for somatic SV prediction using paired tumor-normal WGS data. ...doi:10.1093/bioinformatics/btw605 pmid:27659451 pmcid:PMC5254081 fatcat:pqehpwzvt5bczhe5h4ftf7x5ua