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The sequence-structure-function paradigm of proteins has been changed by the occurrence of intrinsically disordered proteins (IDPs). ... Benefiting from the structural disorder, IDPs are of particular importance in biological processes like regulation and signaling. ... Author Contributions Jinku Bao and Jing Li proposed the original idea for this work. Yu Feng and Xiaoyun Wang collected information about IDPs predictors. ...doi:10.3390/ijms161023446 pmid:26426014 pmcid:PMC4632708 fatcat:zidnpfwb2jhrpgqoezjjsd6qhq
Springer Series in Bio-/Neuroinformatics
We also discuss in more detail approaches that predict disordered regions and specific regions involved in protein binding by modeling the physical background of protein disorder. ... disorder prediction algorithms. ... Accordingly, POODLE-I is based on a workflow approach for combining prediction results from the POODLE series, the elements of which are individual prediction algorithms. ...doi:10.1007/978-3-642-28554-7_16 fatcat:bhyajefglngl5mx67tajdccanq