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Assessing the Effectiveness of Direct Data Merging Strategy in Long-Term and Large-Scale Pharmacometabonomics

Xuejiao Cui, Qingxia Yang, Bo Li, Jing Tang, Xiaoyu Zhang, Shuang Li, Fengcheng Li, Jie Hu, Yan Lou, Yunqing Qiu, Weiwei Xue, Feng Zhu
2019 Frontiers in Pharmacology  
Because of the extended period of clinic data collection and huge size of analyzed samples, the long-term and large-scale pharmacometabonomics profiling is frequently encountered in the discovery of drug  ...  So far, integration of the results (ReIn) from multiple experiments in a large-scale metabolomic profiling has become a widely used strategy for enhancing the reliability and robustness of analytical results  ...  PINCAGE: probabilistic integration of cancer genomics data for perturbed gene identification and sample classification.  ... 
doi:10.3389/fphar.2019.00127 pmid:30842738 pmcid:PMC6391323 fatcat:y6irigbfijbwjbsjspbwtax2wa