Filters








1,679 Hits in 3.2 sec

PID Control of Biochemical Reaction Networks [article]

Max Whitby, Luca Cardelli, Marta Kwiatkowska, Luca Laurenti, Mirco Tribastone, Max Tschaikowski
2019 arXiv   pre-print
In this work we consider Biochemical Reaction Networks (CRNs) as a paradigm for modelling biochemical systems and provide the first implementation of a derivative component in CRNs.  ...  By relying on this component, we present a CRN implementation of a feedback control loop with Proportional-Integral-Derivative (PID) controller and apply the resulting control architecture to regulate  ...  INTRODUCTION Biochemical Reaction Networks (CRNs) are a widely used formalism to describe biochemical systems [1] .  ... 
arXiv:1903.10390v1 fatcat:bsiva7aj75f4jhgjoyh26oecvy

Parameter Turning of PID Controller Based on Molecular Beacon DNA Computing

Yourui Huang, Xiaomin Tian, Jing Wang, Hongping Zhou
2012 Journal of Software  
the performance of the control system.  ...  Molecular beacon deoxyribonucleic acid computing is new research focus of intelligent control theory in recent years, it is also new bionic algorithm.  ...  ACKNOWLEDGMENT The work is supported by the National Natural Science Foundation of China (61073101) and Anhui Provincial University Key Project of Natural Science (KJ2011A095)  ... 
doi:10.4304/jsw.7.10.2223-2228 fatcat:gg56ccdkdjfgdj5xnwzhe2p5sm

Statistical and Integrative Approach for Constructing Biological Network Maps

Hiroyuki Kurata, Natsumi Shimizu, Kanako Misumi
2004 Genome Informatics Series  
In the biochemical map, the individual reactions are reliable, but the number of the reactions is limited, because molecular biology requires extensive experiments to verify them.  ...  A goal of systems biology is to build a concrete biochemical network map, which provides an important instruction to trace the pathways of interest or to understand the mechanism of a biological system  ...  Acknowledgments This study was carried out as a part of The Project for Development of a Technological Infrastructure for Industrial Bioprocesses on R&D of New Industrial Science and Technology Frontiers  ... 
doi:10.11234/gi1990.15.2_161 fatcat:slmipqaqofbwvfco2ln2v4s4ju

Modeling of Multiple Steady-state Behavior and Control of a Continuous Bioreactor

Durga Prasad, Munna Kumar, Anupam Srivastav, R. S. Singh
2019 Indian Journal of Science and Technology  
performance of the bioreactor, based on an unstable transfer function. strate concentration required; etc. had been used for the designing of biochemical control.  ...  IMC PID controller has been designed at the unstable steady-state (optimum) operating point to control the biomass concentration in the bioreactor, by manipulating the (inlet) Dilution rate.  ...  In 15 proposed studied the performance of digital control used for stabilizing the biochemical process in comparison to other PID controllers as shown in Figure 1 .  ... 
doi:10.17485/ijst/2019/v12i11/140476 fatcat:7u5rbcov7vf6jfgv3wnos44mvm

Statistical and integrative approach for constructing biological network maps

Hiroyuki Kurata, Natsumi Shimizu, Kanako Misumi
2004 Genome Informatics Series  
In the biochemical map, the individual reactions are reliable, but the number of the reactions is limited, because molecular biology requires extensive experiments to verify them.  ...  A goal of systems biology is to build a concrete biochemical network map, which provides an important instruction to trace the pathways of interest or to understand the mechanism of a biological system  ...  Acknowledgments This study was carried out as a part of The Project for Development of a Technological Infrastructure for Industrial Bioprocesses on R&D of New Industrial Science and Technology Frontiers  ... 
pmid:15706502 fatcat:shtjri6ho5g6ze3245bdpv57ju

Dissolved Oxygen Control in Activated Sludge Process Using a Neural Network-Based Adaptive PID Algorithm

Xianjun Du, Junlu Wang, Veeriah Jegatheesan, Guohua Shi
2018 Applied Sciences  
The powerful learning and adaptive ability of the RBF neural network makes the adaptive adjustment of the PID parameters to be realized.  ...  A Radial Basis Function (RBF) neural network (NN)-based adaptive PID (RBFNNPID) algorithm is proposed and simulated in this paper for better control of DO in an activated sludge process-based wastewater  ...  AE is mainly used in the last three units of the biochemical reaction tanks.  ... 
doi:10.3390/app8020261 fatcat:usdv7ljf6fgopiliw7w2hbcuxu

A Hybrid Intelligent Optimal Control System Design for Wastewater Treatment Process

Junfei Qiao, Gaitang Han, Honggui Han, Cuili Yang, Wei Li
2017 Information Technology and Control  
Compared to the proportional-integral-derivative (PID) and data-driven adaptive optimal controller (DDAOC) methods, simulation results of the method proposed in this paper show better performance.  ...  To solve this problem, a control optimization system based on hybrid intelligent technology is proposed in this paper.  ...  biochemical reactions process can be controlled.  ... 
doi:10.5755/j01.itc.46.3.16061 fatcat:3k2mkepp4vghta64im6tfotyte

Optimization of electrochemical parameters in microbial fuel cell system based on Fuzzy-PID and CMAC neural network

Chengcai Fu, Fengying Ma
2018 Journal of Electrochemical Science and Engineering  
The bioelectrochemical reaction in MFC system is highly complex, serious nonlinear and time-delay dynamic process, in which the optimal control of electrochemical parameters is still a considerable challenge  ...  neural network was proposed.  ...  for biochemical reaction process showing serious nonlinearity and hysteresis in the cell.  ... 
doi:10.5599/jese.636 fatcat:47a76tsjonfb5dhkaku3grtp5y

Efficient Fuzzy Control of a Biochemical Reactor

Anna Vasickaninová, Monika Bakošová, Juraj Oravec, Michaela Horváthová
2020 Chemical Engineering Transactions  
A type-1 fuzzy PID controller was designed to temperature control in a biochemical reactor. The fuzzy PID controller was also designed using type-2 fuzzy sets.  ...  The advantage of the fuzzy control is that it can be used very successfully for control of strongly non-linear processes and processes that are difficult to model because of complicated reaction kinetics  ...  Acknowledgements The authors gratefully acknowledge the contribution of the Scientific Grant Agency of the Slovak Republic under the grant 1/0545/20.  ... 
doi:10.3303/cet2081015 doaj:4dfaa96d7cf74dc3a7136c002549d897 fatcat:fhtkx4nx5fahdgh2f6qejsrfcu

ConsensusPathDB—a database for integrating human functional interaction networks

Atanas Kamburov, Christoph Wierling, Hans Lehrach, Ralf Herwig
2008 Nucleic Acids Research  
(protein-protein interactions, biochemical reactions, gene regulatory interactions), and covering 1738 pathways.  ...  Furthermore, we describe the functionality of the ConsensusPathDB web interface, where users can search and visualize interaction networks, upload, modify and expand networks in BioPAX, SBML or PSI-MI  ...  Integration of interaction data could only be achieved because the original data was provided in an excellently documented way. Conflict of interest statement. None declared.  ... 
doi:10.1093/nar/gkn698 pmid:18940869 pmcid:PMC2686562 fatcat:xaeqf3acsjgalo6vb7fymcu3pm

PAX2GRAPHML: a Python library for large-scale regulation network analysis using BIOPAX

François Moreews, Hugo Simon, Anne Siegel, Florence Gondret, Emmanuelle Becker, Lenore Cowen
2021 Bioinformatics  
Biochemical reactions and regulatory interactions are homogeneously described by regulated reactions involving substrates, products, activators and inhibitors as elements.  ...  The concept of regulated reactions, which allows connecting regulatory, signaling and metabolic levels, has been used.  ...  By managing BioPAX data extraction into regulated graphs, PAX2GRAPHML simplifies the implementation of many methods for regulation network analysis and understanding of the controlling steps of the biological  ... 
doi:10.1093/bioinformatics/btab441 pmid:34128961 pmcid:PMC8665752 fatcat:iiutomv2fze7fp6jxkwmtenyoa

Maximized redundant and synergistic information transfers predict the rise in the output gene expression noise in a generic class of coherent type-1 feed-forward loop networks [article]

Md Sorique Aziz Momin, Ayan Biswas
2021 bioRxiv   pre-print
with the output gene expression dynamics in the C1-FFL class of network motifs.  ...  Since, the output gene product serves essential physiological purposes in the cell, a predictive estimate of its noise level is supposed to be of considerable biophysical utility.  ...  The dominance of R sx→y over S sx→y as documented in Fig. 2 (a) is also significantly observed in other small networks under the control of different tunable biochemical parameters [34] .  ... 
doi:10.1101/2021.09.12.459930 fatcat:ck2dxxfkxjeavhijsmkx47v2q4

An integrative modeling framework reveals plasticity of TGF-β signaling

Geoffroy Andrieux, Michel Le Borgne, Nathalie Théret
2014 BMC Systems Biology  
The TGF-β transforming growth factor is the most pleiotropic cytokine controlling a broad range of cellular responses that include proliferation, differentiation and apoptosis.  ...  Differential models describe the dynamics of the TGF-β canonical pathway, but modeling the non-canonical networks constitutes a major challenge.  ...  The choice of PID is fully justified by the observation that, unlike other databases, PID formalizes signal propagation instead of describing biochemical reactions.  ... 
doi:10.1186/1752-0509-8-30 pmid:24618419 pmcid:PMC4007780 fatcat:q55ydcqoendevkhdfrnzle5mpq

PathPPI: an integrated dataset of human pathways and protein-protein interactions

HaiLin Tang, Fan Zhong, Wei Liu, FuChu He, HongWei Xie
2015 Science China Life Sciences  
We developed a series of rules for transforming protein interactions from pathway to binary model, and the protein interactions from seven pathway databases, including PID, BioCarta, Reactome, NetPath,  ...  Many challenges remain in terms of the integration of heterogeneous data from pathways and PPIs because such data are generally represented by different standards.  ...  Biochemical reaction Transport TR, TBRR     Metabolic  reaction catalysis METABOLIC_CATALYSIS SEQUENTIAL_CATALYSIS REACTS_WITH Biochemical reaction Table S2 S2 Mapping relationships  ... 
doi:10.1007/s11427-014-4766-3 pmid:25591449 fatcat:2ls5wkj4ojhnng7lkexqmgkj4q

Temperature control of fermentation bioreactor for ethanol production using IMC-PID controller

Munna Kumar, Durga Prasad, Balendu Shekher Giri, Ram Sharan Singh
2019 Biotechnology Reports  
Internal model control based proportional integral derivative (IMC-PID) controller design method was proposed for unstable second order time delay with RHP zero (USOPDT) and successfully tested to the  ...  The temperature of the bioreactor was successfully controlled by proposed controller in both cases setpoint and disturbance change.  ...  Acknowledgments The authors are grateful to the Ministry of Human Resource Development, India (MHRD, India) for providing financial support and the Indian Institute of Technology (BHU) for providing lab  ... 
doi:10.1016/j.btre.2019.e00319 pmid:30911471 pmcid:PMC6416663 fatcat:4kf3ubujnrfang7gjghauvlpmq
« Previous Showing results 1 — 15 out of 1,679 results