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Linking systemic angiogenic markers to synovial vascularization in rheumatoid arthritis

Agathe Leblond, Sonia Pezet, Anne Priscille Trouvin, Muriel Elhai, Virginie Gonzalez, Yannick Allanore, Jérôme Avouac, Chi Zhang
2018 PLoS ONE  
Ultrasound (US) is sensitive for detection of power Doppler (PD) vascularization.  ...  on 32 joints.  ...  Since our previous analysis focused on the highest PDUS semiquantitative scale detected for each patient, we next studied the association between angiogenic marker levels and the global arthritis sum score  ... 
doi:10.1371/journal.pone.0203607 pmid:30188942 pmcid:PMC6126858 fatcat:g3esa4y63fgxdkgoey4hdjsgvi

Preserved Versus Preservative-Free Latanoprost for the Treatment of Glaucoma and Ocular Hypertension: A Post Hoc Pooled Analysis

Paul Harasymowycz, Cindy Hutnik, Jean-François Rouland, Francisco J Muñoz Negrete, Mario A Economou, Philippe Denis, Christophe Baudouin
2021 Advances in Therapy  
A pooled analysis was performed of data from five published studies. The primary outcome was tolerability as evaluated by the severity of hyperemia.  ...  The secondary objectives were patient tolerance based on a composite ocular surface disease (OSD) score arising from ocular signs and symptoms, patient and investigator satisfaction, and a comparison of  ...  Figure 1 presents the grading of conjunctival hyperemia at baseline and day 84 for each group.  ... 
doi:10.1007/s12325-021-01731-9 pmid:33891269 fatcat:zqdhfhkfgrhkdjabgswmcytnhq

A Fully Automated Pipeline for a Robust Conjunctival Hyperemia Estimation

Nico Curti, Enrico Giampieri, Fabio Guaraldi, Federico Bernabei, Laura Cercenelli, Gastone Castellani, Piera Versura, Emanuela Marcelli
2021 Applied Sciences  
Purpose: Many semi-automated and fully-automated approaches have been proposed in literature to improve the objectivity of the estimation of conjunctival hyperemia, based on image processing analysis of  ...  Lastly, we implemented a predictive model for the conjunctival hyperemia using these features.  ...  Data Availability Statement: Data available on request due to privacy restrictions. Conflicts of Interest: The authors declare no conflict of interest.  ... 
doi:10.3390/app11072978 fatcat:shfoi4irzzbwvl343whhox47bi

Impact of pterygium on the ocular surface and meibomian glands

Ana Claudia Viana Wanzeler, Italo Antunes França Barbosa, Bruna Duarte, Eduardo Buzolin Barbosa, Daniel Almeida Borges, Monica Alves, Deepak Shukla
2019 PLoS ONE  
To analyze how ocular surface parameters correlate to presence of pterygium and investigate the possible impact of pterygia on tear film findings and meibomian glands findings.  ...  The advantage of using the image analysis method is that one can eliminate individual variability and the bias of subjective classification.  ...  Interestingly, in 54% of the upper eyelids and 77% of the lower eyelids, the meibomian gland loss appeared nasally in the same localization of the pterygium. Tables 4 and 5 .  ... 
doi:10.1371/journal.pone.0213956 pmid:31513590 pmcid:PMC6742459 fatcat:attknfhg55dw7nfxnkitwb4vsu

Bimatoprost 0.01% vs bimatoprost 0.03%: a 12-month prospective trial of clinical and in vivo confocal microscopy in glaucoma patients

M Figus, M Nardi, P Piaggi, M Sartini, G Guidi, L Martini, S Lazzeri
2014 Eye (London. 1987)  
Results Global clinical score (the sum of pruritus, stinging/burning, blurred vision, sticky eye sensation, eye dryness sensation, and foreign body sensation) significantly decreased in the bimatoprost  ...  All functional parameters and conjunctival hyperemia improved in the bimatoprost 0.01% group at each follow-up visit (Po0.05) and in comparison with bimatoprost 0.03% (Po0.05).  ...  Clinical assessment parameters Global clinical score ranged from 0 (absence of symptoms) to 18 (maximum severity of symptoms) corresponding to the sum of individual parameters that were scored on a four-grade  ... 
doi:10.1038/eye.2013.304 pmid:24434659 pmcid:PMC3983628 fatcat:eb25dltbi5gl3mh7tv3b2amgwu

Corneal Swelling with Cosmetic etafilcon A Lenses versus No Lens Wear

Amir M. Moezzi, Jalaiah Varikooty, Marc Schulze, William Ngo, Kathrine Osborn Lorenz, Danielle Boree, Lyndon W. Jones
2016 Optometry and Vision Science  
Subjective grading of corneal staining and limbal/bulbar hyperemia were also monitored. Results.  ...  No clinically significant differences were distinguished between the lenses and NLW for corneal staining and limbal/bulbar hyperemia. Conclusions.  ...  At the same time and on the same scale, the maximum grade of average bulbar hyperemia in any quadrant with any study contact lens was not more than 0.20 grade greater than the NLW (Fig. 5) .  ... 
doi:10.1097/opx.0000000000000840 pmid:26945176 pmcid:PMC4883641 fatcat:d6qy35hzyjb3zgrfjqybcoagma

Application of artificial intelligence in anterior segment ophthalmic diseases: diversity and standardization

Xiaohang Wu, Lixue Liu, Lanqin Zhao, Chong Guo, Ruiyang Li, Ting Wang, Xiaonan Yang, Peichen Xie, Yizhi Liu, Haotian Lin
2020 Annals of Translational Medicine  
Artificial intelligence (AI) based on machine learning (ML) and deep learning (DL) techniques has gained tremendous global interest in this era.  ...  As an image-centric subspecialty, ophthalmology has become one of the frontiers of AI research.  ...  Imaging modalities Image features Application Slit light Cataract detection and grading Conjunctival hyperemia grading Cataract detection and grading High intraocular pressure detection Identification  ... 
doi:10.21037/atm-20-976 pmid:32617334 pmcid:PMC7327317 fatcat:map3u5bhmramjj5qgfqkyfuate

Ocular Surface Failure in Urban Syndrome

Marco Antonini, Daniele Gaudenzi, Sara Spelta, Giancarlo Sborgia, Maria Poddi, Alessandra Micera, Roberto Sgrulletta, Marco Coassin, Antonio Di Zazzo
2021 Journal of Clinical Medicine  
This study aims to investigate the effects of topical glycerophosphoinositol (GPI) eye drops on the signs and symptoms of US.  ...  These patients are characterized by persistent dysregulation of ocular surface para-inflammation, causing chronic low-grade inflammation and ocular discomfort, with significant consequences for occupational  ...  ., Barkley, CA, USA), was used for statistical analysis.  ... 
doi:10.3390/jcm10143048 fatcat:zveoexw4ivf4bfffy7f2sltcfq

Ultrasonography and color Doppler in juvenile idiopathic arthritis: diagnosis and follow-up of ultrasound-guided steroid injection in the ankle region. A descriptive interventional study

Louise Laurell, Michel Court-Payen, Susan Nielsen, Marek Zak, Mikael Boesen, Anders Fasth
2011 Pediatric Rheumatology Online Journal  
Doppler-US detected synovial hypertrophy, effusion and hyperemia and US was used for guidance of steroid injection and to assess treatment efficacy.  ...  The aim of the study was to evaluate the role of ultrasonography (US) of the ankle and midfoot (ankle region) in JIA.  ...  Acknowlegments And Funding The authors thank the Foundation for Assistance of Disabled in Skåne, the Gyllenstiernska Krapperup Foundation, the Samariten Foundation, the Petter Silfverskiöld Foundation  ... 
doi:10.1186/1546-0096-9-4 pmid:21276257 pmcid:PMC3041992 fatcat:3q773eqaabcwje3kmj7xbkwqnq

Vocal cordopathy consequent to bronchial asthma inhalation therapy

Ahmed Mohammed Abumossalam, Hanan Abdelsattar Ahmed, Omar Mohamed Ibrahim, Talal Mohamad Saad Algreisy, Abdullah Mohmad Al-Shenqiti
2020 Egyptian Journal of Bronchology  
Vocal cords signify an imperative lane for air flow in and out of the respiratory tract along with a phonetic role.  ...  Conclusion: Inhalation therapy as a form of asthma medication correlated with major counter effects on vocal cords with well-recorded laryngeal hyperemia, edema, and vocal nodules in addition to fungal  ...  Collected the data from the outpatient clinic and evaluated the asthmatic cases. Conducted the statistical analysis and the paper manuscript writings and repeated revisions. Dr. O.I. and Dr.  ... 
doi:10.1186/s43168-020-00010-5 fatcat:uzv3dkzbsfd77b6vpwfdpgzwvu

Semiprotective Effects of Hempseed Oil on Carbon Tetrachloride-induced Hepatotoxicity in Male Rats: An Ultra-short Toxicological Intervention

Mona Hashemzadeh, Aliasghar Moghaddam, Isaac Karimi, Zahra Minoosh Siavosh Haghighi, Shahin Hassanpour
2017 Journal of Chemical Health Risks  
In all treated groups, toxicity was induced by i.p. injection of CCl4 (0.5 ml/kg) for two consecutive days and hemp seed, oil was gavaged at 8 ml/kg in respective group once daily for one week.  ...  This study was designed to investigate the protective activity of hempseed oil on carbon tetrachloride (CCl4) hepatotoxicity in male rats at Islamic Azad University, Saveh Branch, Saveh, Iran in 2015.  ...  Groups Heart Kidney Liver Control Normal Normal Normal TCC Necrosis (grade 3) Atrophy and pyknotic cells (grade 3) Hepatoxicity (grade 3) One of the most striking features of this  ... 
doaj:03008f6dd5fe45c59aa11d8196b06e40 fatcat:ttuet46ahfdnzknpphwcdyahpe

A 3-day regimen with azithromycin 1.5% eyedrops for the treatment of purulent bacterial conjunctivitis in children: efficacy on clinical signs and impact on the burden of illness

John Stolz, Dominique Bremond-Gignac, Riadh Messaoud, Sihem Lazreg, Claude Speeg-Schatz, Didier Renault, Frédéric Chiambaretta
2015 Clinical Ophthalmology  
Purpose: To compare the efficacy of azithromycin 1.5% versus tobramycin 0.3% eyedrops on clinical ocular signs and symptoms of bacterial conjunctivitis in children and to assess the parents' satisfaction  ...  Such improved convenience is likely to improve compliance and lessen the burden of illness for patients and carers.  ...  Acknowledgments John Stolz provided editorial support in the preparation of the manuscript. This support was reim bursed by Laboratoires Théa.  ... 
doi:10.2147/opth.s78747 pmid:25945033 pmcid:PMC4408937 fatcat:hcpvlgbdsrfkvp65g44qo6yqw4

Pathologic Continuum of Acute Appendicitis

Lauren Chan, Lewis K. Shin, Reetesh K. Pai, R. Brooke Jeffrey
2011 Ultrasound Quarterly  
Features of an uncomplicated appendicitis include size greater than 6 to 7 mm, hyperemia on color Doppler, mural thickening, and an intact echogenic submucosal layer.  ...  Appendicitis is one of the most common causes of the acute abdomen often requiring emergent surgery.  ...  The size and the degree of ''localization'' of the abscesses are both highly variable.  ... 
doi:10.1097/ruq.0b013e31821b6eea pmid:21606789 fatcat:4ivujzu4srexlj6tfeffx6plse

Permissible Arterial Occlusion Time in Aneurysm Surgery: Postoperative Hyperperfusion Caused by Temporary Clipping

Yuzo ARAKI, Hiromichi ANDOH, Mikito YAMADA, Kei NAKATANI, Takashi ANDOH, Noboru SAKAI
1999 Neurologia medico-chirurgica  
The relationship between hyperperfusion and temporary clipping was evaluated to determine the safe limit for the duration of temporary clipping in aneurysm surgery.  ...  Twenty-one patients surgically treated for a ruptured aneurysm were examined using xenon-enhanced computed tomography on postoperative days 4 to 13.  ...  Just as the prognosis for patients with head trauma depends on the extent of hyperemia, the extent of hyperperfusion in patients with SAH seems to affect outcome, although vasospasm and severity of initial  ... 
doi:10.2176/nmc.39.901 pmid:10658450 fatcat:2m22hxv4ofcthesr6utqrbylmi

Cardiac MRI and Myocardial Injury in COVID-19: Diagnosis, Risk Stratification and Prognosis

Saagar K. Sanghvi, Logan S. Schwarzman, Noreen T. Nazir
2021 Diagnostics  
Cardiac magnetic resonance imaging (CMR) is the preferred imaging modality for non-invasive evaluation in acute myocarditis, enabling risk stratification and prognostication.  ...  The growing use of CMR in clinical practice to assess myocardial injury will improve understanding of the acute and chronic sequelae of myocardial inflammation from various pathological etiologies.  ...  When a T2 signal intensity (SI) is unable to be localized, increased global SI can still be identified by taking a ratio of the myocardial SI referenced to skeletal muscle SI within the same image called  ... 
doi:10.3390/diagnostics11010130 pmid:33467705 pmcid:PMC7830889 fatcat:hxxkxvx7ffbijdyl7ei5wpslpi
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