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A Fully Automated Pipeline for a Robust Conjunctival Hyperemia Estimation

Nico Curti, Enrico Giampieri, Fabio Guaraldi, Federico Bernabei, Laura Cercenelli, Gastone Castellani, Piera Versura, Emanuela Marcelli
2021 Applied Sciences  
Purpose: Many semi-automated and fully-automated approaches have been proposed in literature to improve the objectivity of the estimation of conjunctival hyperemia, based on image processing analysis of  ...  Lastly, we implemented a predictive model for the conjunctival hyperemia using these features.  ...  Data Availability Statement: Data available on request due to privacy restrictions. Conflicts of Interest: The authors declare no conflict of interest.  ... 
doi:10.3390/app11072978 fatcat:shfoi4irzzbwvl343whhox47bi

REVIEW OF MACHINE LEARNING TECHNIQUES IN OPHTHALMOLOGY: A NOVEL APPROACH

Savita Bamal
2020 International Journal of Technical Research & Science  
In this paper, we concentrated on the survey of different existing machine learning models utilized for building up a determination framework for human services applications.  ...  This paper features the survey of existing order models alongside their performances.  ...  Hyperemia Conjunctival Park and Sandberg [6] proposed the methodology of transforming the extracted features into grading scales using a radial basis function network (RBF).  ... 
doi:10.30780/specialissue-icaccg2020/011 fatcat:4h2rcfgv2fhllkoryq2ca3y2rm

Classifying Red and Healthy Eyes using Deep Learning

Sherry Verma, Latika Singh, Monica Chaudhry
2019 International Journal of Advanced Computer Science and Applications  
This paper highlights the work done so far for measuring the level of redness in the eye using various methodologies ranging from statistical ways to machine learning techniques and proposes a methodology  ...  This condition is also termed as hyperemia. The study of this development is vital in diagnosis of various pathologies.  ...  ACKNOWLEDGMENTS We would like to thank Sushant School of Health Science, Ansal University, for helping us in providing test images, clinical guidance and expertise.  ... 
doi:10.14569/ijacsa.2019.0100772 fatcat:5a5akxwu2bb3lgetwq6wmra6ky

Evaluation of Convolutional Neural Network Model for Classifying Red and Healthy Eye

2019 VOLUME-8 ISSUE-10, AUGUST 2019, REGULAR ISSUE  
This paper presents a framework for classifying normal versus red eyes using deep learning technique of convolution neural network (CNN). The model has shown promising results with 94% accuracy.  ...  Conjunctiva hyperemia refers to the redness of the conjunctiva.  ...  ACKNOWLEDGEMENTS Thanks to vision center under School of Health Science, Ansal University, for providing test images, clinical information and advice.  ... 
doi:10.35940/ijitee.l2568.1081219 fatcat:7o6pscke6ndxpkp6jtwsrtglea

Application of artificial intelligence in anterior segment ophthalmic diseases: diversity and standardization

Xiaohang Wu, Lixue Liu, Lanqin Zhao, Chong Guo, Ruiyang Li, Ting Wang, Xiaonan Yang, Peichen Xie, Yizhi Liu, Haotian Lin
2020 Annals of Translational Medicine  
In this review, we provided a summary of the state-of-the-art AI application in anterior segment ophthalmic diseases, potential challenges in clinical implementation and our prospects.  ...  Artificial intelligence (AI) based on machine learning (ML) and deep learning (DL) techniques has gained tremendous global interest in this era.  ...  Another research field lies in automatic conjunctival hyperemia grading, which is usually a subjective and timeconsuming procedure for humans.  ... 
doi:10.21037/atm-20-976 pmid:32617334 pmcid:PMC7327317 fatcat:map3u5bhmramjj5qgfqkyfuate

Clinical Management of Ocular Surface Squamous Neoplasia: A Review of the Current Evidence

Maria Vittoria Cicinelli, Alessandro Marchese, Francesco Bandello, Giulio Modorati
2018 Ophthalmology and Therapy  
"conjunctival carcinoma in situ," with the aim to provide a comprehensive review of the most recent evidence on this distinct clinical entity.  ...  We have reviewed all of the literature on OSSN published in English in the MEDLINE database up to May 2018, using the keywords "ocular surface squamous neoplasia," "squamous conjunctival carcinoma," and  ...  Cryotherapy is then applied to the conjunctival and limbal margins in a ''double freeze slow thaw'' technique, which achieves the rupture of tumor cell membranes and the occlusion of the blood vessels  ... 
doi:10.1007/s40123-018-0140-z pmid:30030703 pmcid:PMC6258579 fatcat:l57i2tv6rbgrfcdr7sizvvtlie

Implementation and Application of an Intelligent Pterygium Diagnosis System Based on Deep Learning

Wei Xu, Ling Jin, Peng-Zhi Zhu, Kai He, Wei-Hua Yang, Mao-Nian Wu
2021 Frontiers in Psychology  
Objective: This study aims to implement and investigate the application of a special intelligent diagnostic system based on deep learning in the diagnosis of pterygium using anterior segment photographs.Methods  ...  in group 3, respectively.Conclusion: The intelligent pterygium diagnosis system based on deep learning can not only judge the presence of pterygium but also classify the severity of pterygium.  ...  The selection of medicines or surgical treatments relies on a doctor's subjective judgment.  ... 
doi:10.3389/fpsyg.2021.759229 pmid:34744935 pmcid:PMC8569253 fatcat:r2anaql5tfcqxlvazflbipgabu

The International Workshop on Meibomian Gland Dysfunction: Report of the Diagnosis Subcommittee

Alan Tomlinson, Anthony J. Bron, Donald R. Korb, Shiro Amano, Jerry R. Paugh, E. Ian Pearce, Richard Yee, Norihiko Yokoi, Reiko Arita, Murat Dogru
2011 Investigative Ophthalmology and Visual Science  
In part I, those aspects of meibomian anatomy and physiology that are relevant to currently available tests are described; a fuller account of the anatomy and physiology is provided in the report of the  ...  In part II, each test and its performance is described in detail. In part III, the practical application of selected tests is summarized and recommendations for future approaches are made.  ...  leads to conjunctival hyperemia and symptoms.  ... 
doi:10.1167/iovs.10-6997f pmid:21450918 pmcid:PMC3072162 fatcat:dwiyfuyr3vctdauksfy47wj5wa

The International Workshop on Meibomian Gland Dysfunction: Report of the Clinical Trials Subcommittee

Penny A. Asbell, Fiona J. Stapleton, Kerstin Wickström, Esen K. Akpek, Pasquale Aragona, Reza Dana, Michael A. Lemp, Kelly K. Nichols
2011 Investigative Ophthalmology and Visual Science  
leads to conjunctival hyperemia and symptoms.  ...  Grading scales may be expanded by dividing each lid into quarters and grading the highest level of change in each region. 75 Quantifying selected features in this way offers an opportunity to generate  ... 
doi:10.1167/iovs.10-6997h pmid:21450920 pmcid:PMC3072164 fatcat:kelcv7wfcfex5mpvqiawcsjpu4

The eye in general medicine [chapter]

Tasanee Braithwaite, Richard W. Lee, Peng T. Khaw, Christopher P. Conlon
2020 Oxford Textbook of Medicine  
The major focus of this chapter is the eye in the context of a range of vascular, haematological, neoplastic, inflammatory, endocrine, genetic, metabolic, toxic, and nutritional disorders.  ...  With a basic history and examination of the eyes and vision, the physician can narrow the differential diagnosis and ascertain whether there is any immediate threat to vision or even life.  ...  increased in all forms of  ... 
doi:10.1093/med/9780198746690.003.0618 fatcat:3sekzrir4fhihgzclf5tpo2huy

Challenges in the management of pediatric blepharokeratoconjunctivis / ocular rosacea

Moritz Claudius Daniel, Michael O'Gallagher, Melanie Hingorani, Annegret Dahlmann-Noor, Stephen Tuft
2016 Expert Review of Ophthalmology  
Due to the paucity of pediatric data we also considered information from articles focused on adults.  ...  Expert commentary: Treatment is based on the assumption that the mechanisms of BKC and rosacea keratitis are the same: meibomian gland dysfunction, bacterial colonisation of the lid margin, delayed type  ...  The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed  ... 
doi:10.1080/17469899.2016.1209408 fatcat:2o2t3pip6jf4doeadszj5bpqiu

A bioinspired synthetic soft hydrogel for the treatment of dry eye

Yu Yu, Derek Wai Yee Chow, Chi Ming Laurence Lau, Guanqun Zhou, Woojin Back, Jing Xu, Sean Carim, Ying Chau
2021 Bioengineering & Translational Medicine  
In a canine clinical study, twice-a-day ocular instillation of the soft hydrogel in combination with cyclosporine for 1 month improved the clinical signs in more than 65% of dog patients previously unresponsive  ...  Under a theoretical framework derived from the Blob model, we chemically crosslinked high molecular weight hyaluronic acid at a concentration close to its overlap concentration (c*), and created synthetic  ...  The reduction in the grading of blepharitis, conjunctival hyperemia and discharge, as well as the increase in tear production as measured by Schirmer's test, indicated the overall health of the ocular  ... 
doi:10.1002/btm2.10227 pmid:34589602 pmcid:PMC8459603 fatcat:4xx4ygpj4bf4bb3gu4zq2odzha

Zika virus infection and pregnancy

Ricardo Simões, Renata Buzzini, Wanderley Bernardo, Florentino Cardoso, Antônio Salomão, Giovanni Cerri
2016 Revista da Associação Médica Brasileira  
The studies were analyzed for relevance and level of evidence according to the Oxford Centre for Evidence Based Medicine 1 (D) table. grade of recoMMendation and strength of evidence A.  ...  of Zika virus infection, with the purpose of assessing the effects on the period of pregnancy and postpartum.  ...  Thus, in order to build a robust knowledge framework of the occurrence of this infection among pregnant women and its effect on the fetus, prospective studies with adequate follow-up are needed.  ... 
doi:10.1590/1806-9282.62.02.108 pmid:27167538 fatcat:d6z5tvrc4vdllfnzdsngw6ldue

Effect of Biopsy Location and Size on Proliferative Capacity of Ex Vivo Expanded Conjunctival Tissue

Jon R. Eidet, Ida G. Fostad, Marie A. Shatos, Tor P. Utheim, Øygunn A. Utheim, Sten Raeder, Darlene A. Dartt
2012 Investigative Ophthalmology and Visual Science  
In the clinic, the identification of goblet cells with impression cytology (Fig. 14B ) (Tseng, 1985) or in vivo confocal microscopy (IVCM) (Dua et al., 2009 ) is one of the key diagnostic features  ...  Characteristic dry eye-related hyperemia in the form of a horizontal band over the conjunctiva limited to the interpalpebral fissure can also be seen.  ... 
doi:10.1167/iovs.11-8269 pmid:22491407 pmcid:PMC3367473 fatcat:ig3i52jkjvbgplsivy2enyvcuu

Report of the Inaugural Meeting of the TFOS i2 = initiating innovation Series: Targeting the Unmet Need for Dry Eye Treatment

Wendy Chao, Carlos Belmonte, José M. Benitez del Castillo, Anthony J. Bron, Harminder S. Dua, Kelly K. Nichols, Gary D. Novack, Stefan Schrader, Mark D. Willcox, James S. Wolffsohn, David A. Sullivan
2016 The ocular surface  
Damage to the ocular surface Whereas “damage to the interpalpebral ocular surface” was a defining feature of DED in the1995 Report of the NEI/Industry Workshop,191 one notable distinction of the  ...  , and provided a framework for further investigation.1 Dr.  ... 
doi:10.1016/j.jtos.2015.11.003 pmid:26774910 fatcat:ezl4qkjudvdwdgczzaayomf6v4
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