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Experimental Genetics of Plasmodium berghei NFU in the Apicoplast Iron-Sulfur Cluster Biogenesis Pathway
2013
PLoS ONE
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We show that the branched apicoplast signal is entirely abolished by azithromycin treatment, while fosmidomycin had no effect on apicoplast morphology. ...
Two of these were predicted to target to the mitochondrion, one ISU/ IscU ortholog (PBANKA_131820) and one NFU1/NfuA ortholog (PBANKA_083170). ...
First, the [Fe-S] cluster is assembled de novo on a scaffold protein. ...
doi:10.1371/journal.pone.0067269
pmid:23805304
pmcid:PMC3689711
fatcat:6glly5luczez3fmrsp2b4p5jnm
What can we do on gravity with antihydrogens?
[article]
1998
arXiv
pre-print
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We discuss the implications of the proposed gravitational redshift experiment on antihydrogens. ...
We show that the result should be the same as on hydrogens in spite of different free-fall accelerations (WEP violation) which may occur if there is a vector fifth-force field. ...
The text-book derivation of the gravitational redshift is a combination of the two steps: (A) Based on the static nature of the setting, one derives ∆t em = ∆t rec , (1) on the intervals of the coordinate ...
arXiv:gr-qc/9806092v1
fatcat:dtqhlj4nrjci5mgygeckziff5m
Iron–sulfur cluster exchange reactions mediated by the human Nfu protein
2016
Journal of Biological Inorganic Chemistry
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Human holo Nfu shows a dimer-tetramer equilibrium with a protein to cluster ratio of 2:1, reflecting the Nfu-bridging [2Fe-2S] cluster. ...
Nfu and the [2Fe-2S](GS) 4 cluster were mixed in a 1:1 ratio at 50 μM each and Wachnowsky et al. ...
Human Nfu exists in two isoforms, one of which is mitochondrial and the other is cytosolic [17] . ...
doi:10.1007/s00775-016-1381-8
pmid:27538573
pmcid:PMC5167677
fatcat:e5bt2k3qh5fvxmpud2gocrb2mi
Thermodynamic and Structural Analysis of Human NFU Conformational Chemistry
2013
Biochemistry
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Human NFU has been implicated in the formation of inorganic sulfide required for cellular ironsulfur cluster biosyntheses. ...
Herein we quantitatively characterize the structural stability of the two domains of human NFU, and in particular the functional C-terminal domain. ...
The influence of N-NFU on C-NFU underlines the importance of the structural role of the N-terminal domain on the native structure of NFU. ...
doi:10.1021/bi400320s
pmid:23796308
pmcid:PMC3855582
fatcat:uexkbjayezegrehl3ml2pmujay
Increasing Need for Uniqueness in Contemporary China: Empirical Evidence
2018
Frontiers in Psychology
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In two studies, we examine how Chinese people's need for uniqueness (NFU) also has changed. In Study 1, we found a significant crossgenerational increase in Chinese participants' self-reported NFU. ...
These findings suggest that the NFU has been rising in China, a historically collectivistic-oriented society. Theoretical and practical implications of our findings were discussed. ...
If younger generations report higher NFU, one possibility is that the NFU has been rising in China. In Study 2, we investigated the change of the Chinese NFU by examining Chinese baby names. ...
doi:10.3389/fpsyg.2018.00554
pmid:29867619
pmcid:PMC5952033
fatcat:vu6ofs2oobe2hnwity6if5li2m
Subcellular compartmentalization of human Nfu, an iron-sulfur cluster scaffold protein, and its ability to assemble a [4Fe-4S] cluster
2003
Proceedings of the National Academy of Sciences of the United States of America
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The results suggest that Nfu can assemble approximately one labile [4Fe-4S] cluster per two Nfu monomers, and support the proposal that Nfu is an alternative scaffold protein for assembly of clusters that ...
Here we report the characterization of human Nfu. ...
Mössbauer spectroscopy was used to characterize the Fe-S cluster assembled on Nfu. ...
doi:10.1073/pnas.1732541100
pmid:12886008
pmcid:PMC187839
fatcat:hlzx2alwabbixavmwadkzzfwa4
Aging Triggers H3K27 Trimethylation Hoarding in the Chromatin of Nothobranchius furzeri Skeletal Muscle
2019
Cells
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and reduced mobility typical of old Nfu. ...
The epigenetic analysis suggested a less accessible and more condensed chromatin in old Nfu skeletal muscle. ...
These evidences support the bioinformatics analyses of sequencing data set performed on aging Nfu. ...
doi:10.3390/cells8101169
pmid:31569376
pmcid:PMC6829443
fatcat:hvvc57kk7faknbjacx7aamc7bq
Nfu facilitates the maturation of iron-sulfur proteins and participates in virulence inStaphylococcus aureus
2014
Molecular Microbiology
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Based on our bioinformatic analyses and studies conducted by alternate groups (reviewed in (Py & Barras, 2010)) we generated a working model for Fe-S cluster biogenesis and trafficking in S. aureus ( Figure ...
An additional gene was identified (nfu; SAUSA300_0839) that displayed homology to the nfuA and nifU genes from A. vinelandii, but the shared homology is confined to the C-terminal "Nfu" domains of these ...
We examined the effect of intracellular H 2 O 2 accumulation on a strain lacking Nfu. ...
doi:10.1111/mmi.12860
pmid:25388433
pmcid:PMC4428306
fatcat:naa7n2padzeevgfwuarrz7kbiu
Page 61 of The Canadian Review of Sociology Vol. 17, Issue 1
[page]
1980
The Canadian Review of Sociology
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At the provincial level, however, there is some indication that the NFU acted more immediately than Unifarm on the issue of compensation for snowed-under crops in 1973 as well as on the crisis in the livestock ...
Canadian Agriculture in the Seventies, p. 312.
20 NFU Conventions have unanimously endorsed the principle of restrictions on who is eligible and not eligible to farm. ...
Iron−Sulfur Cluster Biosynthesis: Characterization of a Molten Globule Domain in Human NFU
2009
Biochemistry
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pair of redox active cysteines and demonstrates thioredoxin-like activity by both binding to and mediating persulfide bond cleavage of sulfur-loaded IscS; the sulfide donor for [2Fe-2S] cluster assembly on ...
Human NFU (also known as HIRIP5) has been implicated in cellular iron-sulfur cluster biosynthesis. ...
The residue numbering shown in Table 1 is based on this sequence. CD spectra of human NFU and its domains. ...
doi:10.1021/bi9002524
pmid:19722697
pmcid:PMC2766508
fatcat:gcanxm7dp5eplcp2atnzuuauzy
Allele-specific mitochondrial stress induced by Multiple Mitochondrial Dysfunctions Syndrome 1 pathogenic mutations modeled in Caenorhabditis elegans
2021
PLoS Genetics
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Five mutant C. elegans alleles focused on the presumptive iron-sulfur cluster interaction domain were generated and analyzed for mitochondrial phenotypes including respiratory dysfunction and oxidative ...
Phenotypes were variable between the mutant nfu-1 alleles and generally presented as an allelic series indicating that not all variants have lost complete function. ...
We thank Iqbal Hamza and Sohini Dutt for insightful discussions and recommendations as well as all members of the NIH C. elegans community for feedback on scientific approaches. ...
doi:10.1371/journal.pgen.1009771
pmid:34449775
pmcid:PMC8428684
fatcat:wfrg4wwd5va4tiffmb667l2c3y
The national farmers union and the British negotiations for membership in the european economic community
1970
Res publica. Politiek-wetenschappelijk tijdschrift van de Lage Landen
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NFU on the negotiations. ...
This meant that the NFU was placing a lot of trust in its , !eadership. lt also meant that the direct influence of the NFU on the talks depended on the abilities and personalities of these two men. ...
doi:10.21825/rp.v5i3.20063
fatcat:6mzi6sb4xjb23pkcgrq5v3m6tq
On the strength of a weak variant of the Axiom of Counting
[article]
2016
arXiv
pre-print
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This result implies that NF+AxCount_≥ proves that consistency of TSTI, and that NFU^-AC+AxCount_≥ proves the consistency of NFU^-AC. ...
This paper shows that NFU^-AC+AxCount_≥ proves the consistency of the Simple Theory of Types with Infinity (TSTI). ...
And [FH] shows that if NFU −AC + AxCount ≤ is consistent then so is NFU −AC + (the function on N defined by n → V n exists). ...
arXiv:1601.04168v2
fatcat:36pyljzobrdmloh7h5zdbdp7fu
Determination of the 5-fluorouracil and N1(2′-furanidyl)uracil in the presence of tegafur by zero-crossing first derivative spectrometry
2002
Journal of Pharmaceutical and Biomedical Analysis
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Ruggedness The ruggedness was established through the spectrometric studies by different analysts on the same apparatus. A study was also performed on a different spectrometer on a different day. ...
Spectrometric measurements The method elaborated is based on the zerocrossing first derivative spectrometry. The absorption spectra of tegafur, 5FU and NFU are shown in Fig. 1 . ...
doi:10.1016/s0731-7085(02)00436-3
pmid:12408928
fatcat:22e4gk7dfnfwnjw26yuzrqzthm
Iron-sulphur cluster assembly in plants: distinct NFU proteins in mitochondria and plastids from Arabidopsis thaliana
2003
Biochemical Journal
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Recent results are in favour of a role for NFU-like proteins in Fe-S cluster biogenesis. These polypeptides share a conserved CXXC motif in their NFU domain. ...
AtNFU1-3 represent a new class of NFU proteins, unique to plants. These polypeptides are made of two NFU domains, the second having lost its CXXC motif. ...
Transformed strains were grown overnight in YNB medium and 5-fold serial dilutions were spotted on YNB-agar mediums (shown from left to right on the Figure). ...
doi:10.1042/bj20021946
pmid:12553879
pmcid:PMC1223333
fatcat:dx5ns2d5rbevdouptkcnwx2x24
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