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Normative shifts of cortical mechanisms of encoding contribute to adult age differences in visual–spatial working memory

Viola S. Störmer, Shu-Chen Li, Hauke R. Heekeren, Ulman Lindenberger
2013 NeuroImage  
The capacity of visual-spatial working memory (WM) declines from early to late adulthood.  ...  Our findings suggest that adult age differences in mechanisms of WM encoding contribute to adult age differences in limits of visualspatial WM capacity.  ...  McDonald and Ben Eppinger for helpful discussions of the data. Viola S.  ... 
doi:10.1016/j.neuroimage.2013.02.004 pmid:23415947 fatcat:rekmfpufavbapdhwolachshcje

The Aging Navigational System

Adam W. Lester, Scott D. Moffat, Jan M. Wiener, Carol A. Barnes, Thomas Wolbers
2017 Neuron  
Changes in spatial working memory are a further likely source of impaired positional coding in old age.  ...  Age-related spatial reference and working memory deficits assessed in the water maze. Neurobiol. Aging 16, 149-160.  ...  Spatial deficits in a virtual water maze in amnesic participants with hippocampal damage. Hippocampus 20, 481-491.  ... 
doi:10.1016/j.neuron.2017.06.037 pmid:28858613 pmcid:PMC5659315 fatcat:hqijqxusbjcxhi7cmzlps7iblm

Cerebral aging: neuropsychological, neuroradiological, and neurometabolic correlates

S E Starkstein, J L Kremer
2001 Dialogues in Clinical Neuroscience  
There is an age-related decline in brain cortical volume, which primarily involves association cortices and limbic regions.  ...  areas in order to maintain performance.  ...  Loss of volume in cortical areas processing visual information was significantly related to lower performance on nonverbal working memory tasks, but the volume of limbic regions was not related to any  ... 
pmid:22034198 pmcid:PMC3181656 fatcat:4mfxd73grnfylatewlnjtx3cie

Neurobehavioural functioning in neonatal intensive care unit graduates in late childhood and early adolescence

W. J. Curtis
2002 Brain  
Multiple regression models suggested that gestational age was of primary importance in predicting spatial memory span, while neurobiological risk was primary in the prediction of spatial working memory  ...  Comparisons between the NICU and control groups on the CANTAB subscales indicated that the NICU children had a shorter spatial memory span length and committed more forgetting errors on a spatial working  ...  Acknowledgements We wish to thank all of the families who, without hesitation, gave their time and effort to participate in this study.  ... 
doi:10.1093/brain/awf159 pmid:12077013 fatcat:ucdf2gummbejrlbixczitsik5a

Musical training during early childhood enhances the neural encoding of speech in noise

Dana L. Strait, Alexandra Parbery-Clark, Emily Hittner, Nina Kraus
2012 Brain and Language  
For children, learning often occurs in the presence of background noise. As such, there is growing desire to improve a child's access to a target signal in noise.  ...  Supported by correlations between auditory working memory and attention and auditory brainstem response properties, we propose that musicians' perceptual and neural enhancements are driven in a top-down  ...  This work was supported by NIH F31DC011457-01 to D.S., NSF 0921275 to N.K. and by the Grammy Research Foundation.  ... 
doi:10.1016/j.bandl.2012.09.001 pmid:23102977 pmcid:PMC3502676 fatcat:wskfnfodsvfmdjahsqfkajbbrq

Early Prefrontal Activation As a Mechanism to Prevent Forgetting in the Context of Interference

Javier García-Pacios, Ricardo Gutiérrez, Elena Solesio, Stephan Moratti, José María Ruiz-Vargas, José María López-Frutos, Laura Lorenzo-López, Francisco Del-Pozo, Fernando Maestú
2013 The American journal of geriatric psychiatry  
To determine whether activation of brain compensatory mechanisms occur during the encoding process in older people.  ...  Objective: Recent research has focused on interference resolution deficits as the main cause of short-term memory decreases in aging.  ...  A minimum norm estimation procedure 28, 29 was applied to estimate the cortical origin of the ERFs.  ... 
doi:10.1016/j.jagp.2012.12.021 pmid:23388623 fatcat:wxh5tyswt5dt7c5gmcywdvoea4

Age-Related Effects in Working Memory Recognition Modulated by Retroactive Interference

E. Solesio-Jofre, L. Lorenzo-Lopez, R. Gutierrez, J. M. Lopez-Frutos, J. M. Ruiz-Vargas, F. Maestu
2011 The journals of gerontology. Series A, Biological sciences and medical sciences  
One of the main causes for age-related declines in working memory is a higher vulnerability to retroactive interference due to a reduced ability to suppress irrelevant information.  ...  Aging is associated with memory impairments (2,3), particularly in working memory (WM). This theoretical construct involves the ability to retain and actively manipulate information temporarily.  ...  FUNDING This work was supported by the Spanish Ministry of Education and Science (grant AP2005-0332); La Xunta de Galicia:Angeles Alvarino Program; and the Spanish Ministry of Science and Innovation (grant  ... 
doi:10.1093/gerona/glr199 pmid:22080502 fatcat:uk22lirc6rg6nleqkzwwiobwq4

Characterizing cognitive aging in humans with links to animal models

Gene E. Alexander, Lee Ryan, Dawn Bowers, Thomas C. Foster, Jennifer L. Bizon, David S. Geldmacher, Elizabeth L. Glisky
2012 Frontiers in Aging Neuroscience  
Here we present a review of selected methods and approaches that have been applied in human research studies to evaluate the effects of aging on cognition, including executive function, memory, processing  ...  With the population of older adults expected to grow rapidly over the next two decades, it has become increasingly important to advance research efforts to elucidate the mechanisms associated with cognitive  ...  The authors would like to acknowledge support from the National Institute on Aging (AG025526, AG19610, AG029421, AG14979, AG037984, and AG036800), the state of Arizona and Arizona Department of Health  ... 
doi:10.3389/fnagi.2012.00021 pmid:22988439 pmcid:PMC3439638 fatcat:weirr7tffbebfjhrw4yr57d53a

How Consistent are Cognitive Impairments in Patients with Cerebellar Disorders?

Dagmar Timmann, Irene Daum
2010 Behavioural Neurology  
It is still an open question as to which areas of cognition the cerebellum contributes, as well as how, and to what extent.  ...  This pattern is illustrated based on general intelligence and verbal working memory, which have been assessed by a large number of authors using comparable tests.  ...  the superior cerebellum (together with the frontal lobe, that is Broca's area, left premotor area, supplementary motor area) contributes to subvocal rehearsal mechanisms of verbal working memory [16]  ... 
doi:10.1155/2010/401048 pmid:20714063 pmcid:PMC5434449 fatcat:pvucmb5txvdafoxnpauo5telgu

Decoding episodic memory in ageing: A Bayesian analysis of activity patterns predicting memory

Alexa M. Morcom, Karl J. Friston
2012 NeuroImage  
This greater distribution of activity in older adults was also linked to poorer individual memory performance, suggesting that it reflects neural ageing, rather than adaptive compensatory responses.  ...  Normal ageing is associated with a decline in episodic memory, and neuroimaging studies in older adults have shown reduced activity in prefrontal cortex and other regions critical for memory function in  ...  In this respect, MVB has an advantage over any analytic approach in which the spatial spread of activity contributes to inference about age-related differences.  ... 
doi:10.1016/j.neuroimage.2011.08.071 pmid:21907810 pmcid:PMC3236995 fatcat:42j5ycrbrjfebmxzfievwxuh6m

Infant fMRI: A Model System for Cognitive Neuroscience

Cameron T. Ellis, Nicholas B. Turk-Browne
2018 Trends in Cognitive Sciences  
This same comparative perspective can be applied to early development -the environment, behavior, and brains of infants provide a model system for understanding how the mature brain works.  ...  Here we discuss potential lessons from infant fMRI for several domains of adult cognition and consider the challenges of conducting such research and how they might be mitigated.  ...  Robust to a variety of testing conditions (including movement), fNIRS can measure cortical activity with potentially similar spatial precision to fMRI in some parts of the brain near to the cortical surface  ... 
doi:10.1016/j.tics.2018.01.005 pmid:29487030 pmcid:PMC5911209 fatcat:ikr6vjybojex3dix2rloogtpca

Effects of aging on the neural correlates of successful item and source memory encoding

Nancy A. Dennis, Scott M. Hayes, Steven E. Prince, David J. Madden, Scott A. Huettel, Roberto Cabeza
2008 Journal of Experimental Psychology. Learning, Memory and Cognition  
To investigate the neural basis of age-related source memory (SM) deficits, young and older adults were scanned with fMRI while encoding faces, scenes, and face-scene pairs.  ...  Functional connectivity between the hippocampus and the rest of the brain was also affected by aging; whereas connections with posterior cortices were weaker in older adults, connections with anterior  ...  Dedifferentiation of visual cortices in aging (Chee et al., 2006; Park et al., 2004; Payer et al., 2006 ) may contribute to this encoding impairment.  ... 
doi:10.1037/0278-7393.34.4.791 pmid:18605869 pmcid:PMC2752883 fatcat:nn3wktwzhrcofggpowldzts4em

The Importance of Sound for Cognitive Sequencing Abilities

Christopher M. Conway, David B. Pisoni, William G. Kronenberger
2009 Current Directions in Psychological Science  
Accordingly, the absence of sound early in development may result in disturbances to these sequencing skills. In support of this hypothesis, we present two types of findings.  ...  Under conditions of auditory deprivation, auditory scaffolding is absent, resulting in neural reorganization and a disturbance to cognitive sequencing abilities.  ...  We wish to thank Arthur Glenberg for suggesting the embodied account as a possible mechanism underlying the auditory scaffolding effects.  ... 
doi:10.1111/j.1467-8721.2009.01651.x pmid:20725604 pmcid:PMC2923391 fatcat:45cmlvx7dna53c52t7i6k35hxe

Differential contribution of specific working memory components to mathematics achievement in 2nd and 3rd graders

M.L. Meyer, V.N. Salimpoor, S.S. Wu, D.C. Geary, V. Menon
2010 Learning and Individual Differences  
The contribution of the three core components of working memory (WM) to the development of mathematical skills in young children is poorly understood.  ...  We propose that these changes reflect a shift from prefrontal to parietal cortical functions during mathematical skill acquisition. Implications for learning and individual differences are discussed.  ...  This research was supported by grants from the National Institutes of Health (NICHD-HD047520 and NICHD-HD059205) and the National Science Foundation (BCS/DRL-075034) to VM.  ... 
doi:10.1016/j.lindif.2009.08.004 pmid:21660238 pmcid:PMC3109434 fatcat:inyykmjhtvhxdmwnil3fgvbfa4

Working Memory And Brain Tissue Microstructure: White Matter Tract Integrity Based On Multi-Shell Diffusion MRI

Sohae Chung, Els Fieremans, Nuri E. Kucukboyaci, Xiuyuan Wang, Charles J. Morton, Dmitry S. Novikov, Joseph F. Rath, Yvonne W. Lui
2018 Scientific Reports  
There is specific interest in understanding the microstructural correlates that contribute to such macroscopic changes as well as inform more subtle differences in working memory performance.  ...  It is composed of three main components: (1) the phonological loop which provides short-term memory traces for sounds by continuously refreshing the information through silent rehearsal; (2) the visual-spatial  ...  Acknowledgements This work was supported in part by grant funding from the National Institutes of Health (NIH): R01 NS039135-11 and R21 NS090349, National Institute for Neurological Disorders and Stroke  ... 
doi:10.1038/s41598-018-21428-4 pmid:29453439 pmcid:PMC5816650 fatcat:jgrexsew3nhebmatlcu22gd6my
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