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NiftyPET: a High-throughput Software Platform for High Quantitative Accuracy and Precision PET Imaging and Analysis

Pawel J. Markiewicz, Matthias J. Ehrhardt, Kjell Erlandsson, Philip J. Noonan, Anna Barnes, Jonathan M. Schott, David Atkinson, Simon R. Arridge, Brian F. Hutton, Sebastien Ourselin
2017 Neuroinformatics  
We present a standalone, scalable and high-throughput software platform for PET image reconstruction and analysis.  ...  We focus on high fidelity modelling of the acquisition processes to provide high accuracy and precision quantitative imaging, especially for large axial field of view scanners.  ...  The Florbetapir PET tracer was provided by AVID Radiopharmaceuticals (a wholly owned subsidiary of Eli Lilly & Co).  ... 
doi:10.1007/s12021-017-9352-y pmid:29280050 pmcid:PMC5797201 fatcat:n5z6nee3e5gyfhdqgjosprxzhm

Uncertainty analysis of MR-PET image registration for precision neuro-PET imaging

Pawel J Markiewicz, Julian C Matthews, John Ashburner, David M Cash, David L Thomas, Enrico De Vita, Anna Barnes, M Jorge Cardoso, Marc Modat, Richard Brown, Kris Thielemans, Casper da Costa-Luis (+7 others)
2021 NeuroImage  
We propose a dedicated uncertainty analysis for quantifying the precision of MR-PET registration, centred around the bootstrap resampling of PET list-mode events to generate multiple PET image realisations  ...  The effects of PET image reconstruction parameters, such as the use of attenuation and scatter corrections and different number of iterations, on the precision and accuracy of MR-PET registration were  ...  Acknowledgements The research was also supported by the Medical Research Council (MR/N025792/1) for the Dementias Platform UK MR-PET Partnership. This research was also supported by the  ... 
doi:10.1016/j.neuroimage.2021.117821 pmid:33588030 pmcid:PMC8204268 fatcat:enpett77hbgdpbmiw4lqdexfoi