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Brain stimulation in neuropsychiatry

Gwenn S. Smith, Shawn M. McClintock, Mustafa Husain
2011 International Review of Psychiatry  
There are methods to stimulate brain circuits directly (such as deep brain stimulation (DBS)) or indirectly (such as vagus nerve stimulation (VNS)), which are being assessed for their therapeutic properties  ...  We hope that the papers in this issue convey the excitement and the great potential for brain stimulation approaches, and will encourage the interdisciplinary, translational research that is needed to  ... 
doi:10.3109/09540261.2011.637910 pmid:22200129 pmcid:PMC5675135 fatcat:vbnfh6xtkne4hfatkvai76ntle

Harnessing networks and machine learning in neuropsychiatric care

Eli J Cornblath, David M Lydon-Staley, Danielle S Bassett
2019 Current Opinion in Neurobiology  
The development of next-generation therapies for neuropsychiatric illness will likely rely on a precise and accurate understanding of human brain dynamics.  ...  For simplicity, we will refer to large cross-sectional neuroimaging studies as broad studies and to intensive longitudinal studies as deep studies.  ...  Next, we describe a framework to maximize the clinical translatability of broad and deep neuroimaging studies.  ... 
doi:10.1016/j.conb.2018.12.010 pmid:30641443 pmcid:PMC6839408 fatcat:wzxhhmtu4bbotbiv44pps55ciq

An agenda for neuropsychiatry as a 21st century discipline

Perminder S. Sachdev
2007 Acta Neuropsychiatrica  
Acknowledgements The author is grateful to Angela Russell for manuscript preparation.  ...  Neuropsychiatric treatments 1. Electroconvulsive therapy 2. TMS 3. Vagus nerve stimulation 4. Deep brain stimulation 5. Neurosurgery for psychiatric disorders 6.  ...  Vagus nerve stimulation shows early promise as a treatment for refractory depression (12) , and deep brain stimulation is now being investigated in depression (13) and obsessive-compulsive disorder  ... 
doi:10.1111/j.1601-5215.2006.00173.x pmid:26952792 fatcat:pvssyhwzyjhonomszz7vkhofnm

Neurocircuitry: A Window into the Networks Underlying Neuropsychiatric Disease

Suzanne N Haber, Scott L Rauch
2009 Neuropsychopharmacology  
A comprehensive disclosure for SLR is supplied as Supplemental Material online.  ...  We also thank the ACNP, especially Diane Drexler, and Katie Ris-Vicari at Nature Publishing, for their untiring devotion to this project and its demanding timeline.  ...  In chapter 16, Greenberg et al review neurosurgical treatments, including deep brain stimulation as invasive interventions, taking as an example, obsessive-compulsive disorder.  ... 
doi:10.1038/npp.2009.146 pmid:20010702 pmcid:PMC3055437 fatcat:vhcme7yacjbofnro7edotdf2de

Neuroimaging evaluation of deep brain stimulation in the treatment of representative neurodegenerative and neuropsychiatric disorders

Shichun Peng, Vijay Dhawan, David Eidelberg, Yilong Ma
2021 Bioelectronic Medicine  
In this article, we review some applications of deep brain stimulation for the treatment of several diseases in the field of neurology and psychiatry.  ...  Development of therapeutic approaches with brain stimulation goes in tandem with the use of neuroimaging methodology in every step of the way.  ...  Acknowledgements We are grateful to the continued professional support provided by the Feinstein Institutes for Medical Research.  ... 
doi:10.1186/s42234-021-00065-9 pmid:33781350 fatcat:h4qjs6t2qvea5awq42ymxecmha

Imaging, Technology, and Parkinson's Disease

Nora Vanegas
2019 US Neurology  
Nora Vanegas Dr Vanegas is a neurologist who specializes in deep brain stimulation (DBS) and the treatment of movement disorders including Parkinson's disease, dystonia, and essential tremor.  ...  Dr Vanegas is also a clinical investigator whose research involves clinical and translational areas of movement disorders, specifically the use of brain imaging for the understanding of DBS and the physiology  ...  How are deep brain stimulation devices currently used in Parkinson's disease?  ... 
doi:10.17925/usn.2019.15.1.18 fatcat:xfsnnrctczhyzioqmdyqjlaaz4

Balancing the Brain: Resting State Networks and Deep Brain Stimulation

Morten L. Kringelbach, Alexander L. Green, Tipu Z. Aziz
2011 Frontiers in Integrative Neuroscience  
Over the last three decades, large numbers of patients with otherwise treatment-resistant disorders have been helped by deep brain stimulation (DBS), yet a full scientific understanding of the underlying  ...  In particular, some of the newly identified hubs and connectors within and between resting state networks could become important new targets for DBS, including potentially in neuropsychiatric disorders  ...  (C) Deep brain stimulation causally alters brain activity and future challenges include how to best restore this default network in malignant brain disorders.  ... 
doi:10.3389/fnint.2011.00008 pmid:21577250 pmcid:PMC3088866 fatcat:4gt57iunovcpxb27us4ny5fl2q

Harnessing neuroplasticity for clinical applications

S. C. Cramer, M. Sur, B. H. Dobkin, C. O'Brien, T. D. Sanger, J. Q. Trojanowski, J. M. Rumsey, R. Hicks, J. Cameron, D. Chen, W. G. Chen, L. G. Cohen (+23 others)
2011 Brain  
Promising therapies that may enhance training-induced cognitive and motor learning, such as brain stimulation and neuropharmacological interventions, were identified, along with questions of how best to  ...  To advance the translation of neuroplasticity research towards clinical applications, the National Institutes of Health Blueprint for Neuroscience Research sponsored a workshop in 2009.  ...  with deep brain stimulation-induced gradual effects (e.g. circuit retraining) as seen in neuropsychiatric disorders.  ... 
doi:10.1093/brain/awr039 pmid:21482550 pmcid:PMC3102236 fatcat:6dnm6sewurdhrp74s5lnjed2oi

Using causal methods to map symptoms to brain circuits in neurodevelopment disorders: moving from identifying correlates to developing treatments

Alexander Li Cohen
2022 Journal of Neurodevelopmental Disorders  
circuits for transdiagnostic symptoms and neuroimaging-based endophenotypes may now be feasible for neurodevelopmental disorders using data from cohorts with focal brain anomalies.  ...  treatments and therapies for neurodevelopmental disorders.With new computational and neuromodulatory approaches to interrogating brain networks, opportunities exist for "bedside-to bedside-translation  ...  would normally require deep brain stimulation to reach.  ... 
doi:10.1186/s11689-022-09433-1 pmid:35279095 pmcid:PMC8918299 fatcat:u4gfwj6h5bgk3oxg2i5xlyalzy


Gwenn S Smith, Xiaohua Li, P Jeffrey Conn
2011 Neuropsychopharmacology  
brain stimulation and magnetic stimulation.  ...  Some promising specific mechanisms (cognitive rehabilitation for schizophrenia, cognitive therapy for depression, inflammation for mood disorders, and deep brain stimulation for Parkinson's disease (PD  ... 
doi:10.1038/npp.2011.233 pmid:22157854 pmcid:PMC3238089 fatcat:qaob6tbljfcpbm6opirpg35kiy

Magnetoencephalography as a Tool in Psychiatric Research: Current Status and Perspective

Peter J. Uhlhaas, Peter Liddle, David E.J. Linden, Anna C. Nobre, Krish D. Singh, Joachim Gross
2017 Biological Psychiatry: Cognitive Neuroscience and Neuroimaging  
Finally, we discuss challenges as well as novel methodological developments that could pave the way for widespread application of MEG in translational research with the aim of developing biomarkers for  ...  Because of its potential in delineating normal and abnormal brain dynamics, we propose that MEG provides a crucial tool to advance our understanding of pathophysiological mechanisms of major neuropsychiatric  ...  MEG AND TRANSLATIONAL NEUROIMAGING One of the attractions of MEG for translational research is that the signals it measures can be compared with analogous measures derived from invasive electrophysiology  ... 
doi:10.1016/j.bpsc.2017.01.005 pmid:28424797 pmcid:PMC5387180 fatcat:5qachfklvbbuppsiwxrhbeouuy

Neuropsychiatric Electrophysiology

Nashaat N Boutros
2015 Neuropsychiatric Electrophysiology  
Similarly, the clinical application of electrophysiological assessments of neuropsychiatric disorders is a field that remains in its formative stages, with yet to be developed guidelines for standards  ...  The journal will provide a unique venue for clinical and basic science researchers interested in the pathoneurophysiology and mechanisms of symptom development related to the full range of neuropsychiatric  ...  ), vagal nerve stimulation (VNS), deep brain stimulation (DBS), transcranial direct-current stimulation (tDCS), and magnetic seizure therapy (MST).  ... 
doi:10.1186/s40810-015-0008-6 fatcat:kfrhf2rs7razhmzfudxjk4xqe4

Real-time functional magnetic resonance imaging in obsessive-compulsive disorder

Óscar Gonçalves, Marcelo Camargo Batistuzzo, João Sato
2017 Neuropsychiatric Disease and Treatment  
Real-time functional magnetic resonance imaging (rtfMRI) was introduced as a new therapeutic tool for the self-regulation of brain-mind.  ...  In this review, we describe initial trials testing the use of rtfMRI to target brain regions associated with specific OCD symptoms (eg, contamination), and other mind-brain processes (eg, cognitive -working  ...  As illustrated in Figure 2 , in opposite quadrants are deep brain stimulation 30 (DBS, ie, a method for regulating brain functioning by implanting, deep in the brain, a stimulation device) and self-regulatory  ... 
doi:10.2147/ndt.s121139 pmid:28744133 pmcid:PMC5513821 fatcat:bt65dzodajg53gqyq6o3sqi3uq

Latest Advances in Human Brain Dynamics

Stavros I. Dimitriadis
2021 Brain Sciences  
It is paramount for every neuroscientist to understand the nature of emerging technologies and approaches in investigating functional brain dynamics [...]  ...  Transcranial electrical stimulation (tES) is a noninvasive brain stimulation technique that applies a weak current and electrical current through the cortex of the brain in order to alter brain function  ...  Deep convolutional neural networks and human visual systems have demonstrated common invariances identified or classified after rotation, scaling, and translation transformations.  ... 
doi:10.3390/brainsci11111476 pmid:34827475 pmcid:PMC8615593 fatcat:6nfzglsau5he3nhg7gji3yw2hy

Page 1307 of Psychological Abstracts Vol. 89, Issue 4 [page]

2002 Psychological Abstracts  
Generally, the adaptation effects were di- rection-specific for radiation/rotation, but independent of the direction of test stimulus for translation.  ...  approach to evaluating the patient * Neuropsychiatric evaluation * The mental status examination * Clinical electrophysiology * Neuroimaging ¢ Part III: Applying the approach to neuropsychiatric disorders  ... 
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