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Effects of intensive cognitive-behavioral therapy on cingulate neurochemistry in obsessive–compulsive disorder
2013
Journal of Psychiatric Research
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The neurophysiological bases of cognitive-behavioral therapy (CBT) for obsessive-compulsive disorder (OCD) are incompletely understood. ...
The goal of this pilot study was to determine the relationship between levels of the neurochemically interlinked metabolites glutamate + glutamine (Glx) and N-acetyl-aspartate + N-acetyl-aspartyl-glutamate ...
London, and James T. McCracken for life support in a near terminal stage. ...
doi:10.1016/j.jpsychires.2012.11.010
pmid:23290560
pmcid:PMC3672238
fatcat:rkvvxglnhbbmbinguieh6vmllm
A Critical Review of Magnetic Resonance Spectroscopy Studies of Obsessive-Compulsive Disorder
2013
Biological Psychiatry
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Functional neuroimaging studies have converged to suggest that cortico-striatal-thalamo-cortical (CSTC) circuit dysfunction is a core pathophysiolologic feature of obsessive-compulsive disorder (OCD). ...
We conclude with suggestions for possible future 1 H-MRS studies in OCD. ...
Acknowledgments This work was funded in part by Grant 1K23-MH092397 from the National Institute of Mental Health (BPB) and the David Judah Fund at Massachusetts General Hospital (BPB). ...
doi:10.1016/j.biopsych.2012.06.023
pmid:22831979
pmcid:PMC3504626
fatcat:d2iy7ue2hfbhxdjjqpg663tlki
Brain-behavior relationships in obsessive-compulsive disorder
2001
Seminars in Clinical Neuropsychiatry
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Advances in neuroimaging have led to a greater understanding of brain-behavior relationships in obsessive-compulsive disorder (OCD). ...
This article provides an updated review and analysis of the structural and functional neuroimaging studies in OCD published to date and discusses how evidence from various types of neuroimaging studies ...
Acknowledgment The authors thank several colleagues, especially Lewis R Baxter,Jr, MD, who contributed greatty to the concepts and theofies pfesented here. ...
doi:10.1053/scnp.2001.21833
pmid:11296309
fatcat:zjyaybvvzrcvfbdvbpc63dwskq
Nuclear Neuroimaging in Social Anxiety Disorder: A Review
2018
Journal of Nuclear Medicine
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A recent neuroimaging review of social anxiety disorder focused predominantly on MRI, omitting the contribution of nuclear imaging methods. ...
Evidence for disturbances in neurotransmitter systems in social anxiety disorder is limited but suggestive of both serotonergic and dopaminergic dysfunction. ...
A study that used 123 I-iodobenzamide SPECT to investigate dopaminergic function in SAD patients with comorbid obsessive-compulsive disorder reported dopaminergic deficits in patients with comorbidity, ...
doi:10.2967/jnumed.118.212795
fatcat:nyemt22vrbcbzpktcxiqprmmom
Neurobiology of Posttraumatic Stress Disorder: The Role of Nuclear Neuroimaging
[chapter]
2014
PET and SPECT in Psychiatry
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A recent neuroimaging review of social anxiety disorder focused predominantly on MRI, omitting the contribution of nuclear imaging methods. ...
Evidence for disturbances in neurotransmitter systems in social anxiety disorder is limited but suggestive of both serotonergic and dopaminergic dysfunction. ...
A study that used 123 I-iodobenzamide SPECT to investigate dopaminergic function in SAD patients with comorbid obsessive-compulsive disorder reported dopaminergic deficits in patients with comorbidity, ...
doi:10.1007/978-3-642-40384-2_14
fatcat:bdwwlidln5ctblseb2e4hrgyfq
Brain serotonin synthesis capacity in obsessive-compulsive disorder: effects of cognitive behavioral therapy and sertraline
2018
Translational Psychiatry
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Nordahl may more directly participate in mathematical activity now that he is Professor Emeritus of the Department of Psychiatry and Behavioral Sciences. ...
Acknowledgements This study was supported by funding from Fonds de la Recherche du Quebec -Sante (FRQS). ...
Introduction Obsessive-compulsive disorder (OCD) is a chronic mental illness involving intrusive, unwanted thoughts (obsessions) and persistent mental or behavioral rituals (compulsions) that cause significant ...
doi:10.1038/s41398-018-0128-4
pmid:29666372
pmcid:PMC5904107
fatcat:246b5yt6wvcnheryyeuk23uhfa
Neuroimaging Studies in Eating Disorders
2004
CNS Spectrums
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AbstractThe understanding of the eating disorders (EDs) anorexia (AN) and bulimia nervosa (BN) has undergone remarkable advancements in the past decade. ...
While fewer studies have been done in BN or binge eating disorder, there may be disturbances of serotonin metabolism in similar brain regions. ...
A restricting type (AN-R) has been distinguished from a binge eating/purging type (AN-B/P). 4 Comorbid obsessive-compulsive disorder (OCD), depression, and anxiety are common. 5
Computed Tomography ...
doi:10.1017/s1092852900009639
fatcat:za2b36gbwjeuzptzfiwveq4wxy
The neurobiological link between OCD and ADHD
2014
ADHD Attention Deficit and Hyperactivity Disorders
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Obsessive compulsive disorder (OCD) and attention deficit hyperactivity disorder (ADHD) are two of the most common neuropsychiatric diseases in paediatric populations. ...
The high comorbidity of ADHD and OCD with each other, especially of ADHD in paediatric OCD, is well described. OCD and ADHD often follow a chronic course with persistent rates of at least 40-50 %. ...
MRS
Introduction Obsessive compulsive disorders (OCD) are typically characterized by the presence of recurrent, intrusive, and disturbing thoughts (obsessions) which often elicit anxiety or emotional ...
doi:10.1007/s12402-014-0146-x
pmid:25017045
pmcid:PMC4148591
fatcat:vc3t2qjovfenlltyji6ht3aly4
Obsessive compulsive disorder: a practical guide
2003
Journal of Neurology, Neurosurgery and Psychiatry
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the diagnosis, assessment, and management of obsessive compulsive disorder (OCD). ...
Intuitively depression units are appealing, but it is disappointing that no Obsessive compulsive disorder: a practical guide The stated aim of this book is to provide a practical and accessible guide to ...
doi:10.1136/jnnp.74.11.1602-b
fatcat:usikkbsrfrbx7j3xqdqxuvllr4
Eating Disorders: An Evolutionary Psychoneuroimmunological Approach
2019
Frontiers in Psychology
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We present the mismatch hypothesis as a necessary extension to the current theoretical framework of eating disorders. ...
Eating disorders are evolutionarily novel conditions. They lead to some of the highest mortality rates of all psychiatric disorders. ...
Eating Disorders and Obsessive Compulsive Disorder According to diagnostic criteria, obsession with physical exercise, appearance and food are common in eating disorders (American Psychiatric Association ...
doi:10.3389/fpsyg.2019.02200
pmid:31749720
pmcid:PMC6842941
fatcat:bicujoillvd7fc456ajw3xgjyi
Perspectives in affective disorders, Vol 21
2003
Journal of Neurology, Neurosurgery and Psychiatry
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the diagnosis, assessment, and management of obsessive compulsive disorder (OCD). ...
Intuitively depression units are appealing, but it is disappointing that no Obsessive compulsive disorder: a practical guide The stated aim of this book is to provide a practical and accessible guide to ...
doi:10.1136/jnnp.74.11.1602-a
fatcat:wpfuzxqpofcqngteecvscvctxy
Differential Effects of Electroconvulsive Therapy in the Treatment of Major Depressive Disorder
2020
Neuropsychobiology
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However, as current data is not consistent, future longitudinal investigations should combine modalities such as MRI, MR spectroscopy, and peripheral physiological measures to gain a deeper insight into ...
The present review aims to describe differential antidepressant and cognitive effects of ECT as well as effects on markers of neural activity and connectivity, neurochemistry, and inflammation that might ...
Statement of Ethics The authors have no ethical conflicts to declare.
Disclosure Statement The authors have no conflicts of interests to declare. ...
doi:10.1159/000505553
pmid:32344410
fatcat:pt4ibep3znhuzpsxiqfwdd7y2e
Psychiatric and cognitive disorders in Parkinson's disease
2003
Journal of Neurology, Neurosurgery and Psychiatry
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the diagnosis, assessment, and management of obsessive compulsive disorder (OCD). ...
Intuitively depression units are appealing, but it is disappointing that no Obsessive compulsive disorder: a practical guide The stated aim of this book is to provide a practical and accessible guide to ...
doi:10.1136/jnnp.74.11.1601
pmcid:PMC1738210
fatcat:td5tygcbfre4hoy7n75qvxgz2e
Neuromodulation in the Age of Modern Neuroimaging Technologies
[chapter]
2020
Neurostimulation and Neuromodulation in Contemporary Therapeutic Practice [Working Title]
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Neuroimaging has a variety of main roles in DBS including evaluating the final electrode contact position, localizing the target nucleus, and detecting complications. ...
Most commonly used for the treatment of Parkinson's disease (PD), the deep brain stimulation (DBS) is a new neurosurgical method whose other applications are still under development. ...
Combination of fMRI and PET modalities has provided a terrific opportunity in research to understand the neurochemistry of brain and underlying biochemical nature of brain function. ...
doi:10.5772/intechopen.92737
fatcat:sqggbrbcpjalnnx7pxvor4divq
An Overview of Translationally Informed Treatments for Posttraumatic Stress Disorder: Animal Models of Pavlovian Fear Conditioning to Human Clinical Trials
2015
Biological Psychiatry
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Pre-clinical studies reveal a number of neurotransmitter systems and circuits critical for aversive learning and memory, which have informed the development of therapies used in human clinical trials. ...
Posttraumatic stress disorder (PTSD) manifests after exposure to a traumatic event and is characterized by avoidance/numbing, intrusive symptoms and flashbacks, mood and cognitive disruptions, and hyperarousal ...
Acknowledgments Support was provided by NIH (T32-GM08605, 1F31MH097397, and R01MH096764), the Burroughs Wellcome Fund, and by an NIH/NCRR base grant (P51RR000165) to Yerkes National Primate Research Center ...
doi:10.1016/j.biopsych.2015.06.008
pmid:26238379
pmcid:PMC4527085
fatcat:cvmkrjhweff63beevb4wtswhdq
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