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Neuroanatomical changes in white and grey matter after sleeve gastrectomy

Andréanne Michaud, Mahsa Dadar, Mélissa Pelletier, Yashar Zeighami, Isabel Garcia-Garcia, Sylvain Iceta, Yvonne Yau, Mélanie Nadeau, Simon Marceau, Laurent Biertho, André Tchernof, D. Louis Collins (+2 others)
2020 NeuroImage  
MRI studies show that obese adults have reduced grey matter (GM) and white matter (WM) tissue density as well as altered WM integrity.  ...  The aim of this study is to characterize GM and WM density changes measured with MRI in a longitudinal setting following sleeve gastrectomy, and to determine whether any changes are related to inflammation  ...  acknowledge the contribution of surgeons, nurses, the medical team of the bariatric surgery program at IUCPQ, MRI technicians, Xavier Moreel, Coordinator of the Plateforme d'imagerie avanc ee at IUCPQ, and  ... 
doi:10.1016/j.neuroimage.2020.116696 pmid:32145436 fatcat:ldwk2kagfjep3kfi22nf6ggra4

Neuroanatomical Changes in White and Grey Matter after Sleeve Gastrectomy [article]

Andreanne Michaud, Mahsa Dadar, Melissa Pelletier, Yashar Zeighami, Isabel Garcia-Garcia, Yvonne Yau, Melanie Nadeau, Simon Marceau, Laurent Biertho, Andre Tchernof, Louis D Collins, Denis Richard (+1 others)
2019 bioRxiv   pre-print
MRI studies show that obese adults have reduced grey (GM) and white matter (WM) tissue density as well as altered WM integrity.  ...  Methods: 29 severely obese participants scheduled to undergo sleeve gastrectomy (SG) were recruited.  ...  MRI studies show that obese adults have reduced grey matter (GM) and white matter (WM) tissue density.  ... 
doi:10.1101/678284 fatcat:wlny7ixhdrejbb4vo5ldzhuzsa

Abstracts for Canadian Stroke Conference

2012 Stroke  
Previous studies have examined predictors of treatment costs after Spontaneous Intracerebral Hemorrhage (ICH) in various countries and healthcare systems.  ...  and age (years), gender (female vs. male), Charlson Comorbidity Index (0 vs. ≥1), in-hospital mortality (alive vs. dead), and having surgery (no vs. yes).  ...  matter, white matter, and background/CSF.  ... 
doi:10.1161/01.str.0000422054.44193.87 fatcat:egqdibdvafgrdl6ficwy7hzhwe

ACNP 56th Annual Meeting: Poster Session I, December 4, 2017

2017 Neuropsychopharmacology  
, and immune biomarkers in trauma-exposed women with T2DM.  ...  Hospital, a large county hospital and level 1 trauma center in Atlanta, Georgia.  ...  ) in sleeve gastrectomy patients, with significant reductions from baseline to 12months post-surgery.  ... 
doi:10.1038/npp.2017.264 pmid:29192265 fatcat:psc2w4azgrbfhjtxe6oxrnsdaq

Poster Session II

2015 Neuropsychopharmacology  
Results: We did not find any significant changes in Grey Matter.  ...  , and 3) reductions in frontal, striatal and thalamic white matter FA in ADHD versus OCD that largely corresponded to white matter tracts linking fronto-striato-thalamic circuitry.  ...  This may be due to cannabinoid effects on neurodevelopmental processes occurring before age 17 (2), including maturation in the prefrontal cortex, limbic system and white matter association fibers (3)  ... 
doi:10.1038/npp.2015.326 pmid:26632287 pmcid:PMC4672311 fatcat:ib64i5qmzngvxcpn5hznkcagie

ACNP 59th Annual Meeting: Poster Session III

2020 Neuropsychopharmacology  
These data suggest that symptom chronicity may have a moderating effect on immune activation and its relationship with white matter connections in fronto-limbic pathways.  ...  In both samples, probabilistic tractography was used to examine structural integrity of white matter connections between the hippocampus and anterior cingulate cortex (cingulum bundle) and the amygdala  ...  Methods: Grey matter homogenates were prepared from right hemisphere auditory cortex grey matter of 48 schizophrenia and 48 matched control subjects.  ... 
doi:10.1038/s41386-020-00892-5 pmid:33279936 pmcid:PMC7735201 fatcat:mip4ywutfnfwvmye4u65i6vgg4

ACNP 57th Annual Meeting: Poster Session III

2018 Neuropsychopharmacology  
Enhanced molecular senescence changes contribute to structural brain changes in critical circuits related to episodic memory and executive function in older adults with depression.  ...  This study aims to evaluate the association between SASP index with structural brain changes and cognitive performance in older adults with major depression.  ...  Prior studies showed that laparoscopic sleeve gastrectomy (LSG) promoted structural recovery of gray-(GM) and white-matter (WM) density, WM integrity and cortical morphometry particularly in frontal regions  ... 
doi:10.1038/s41386-018-0268-5 fatcat:wiooxnisvfhovadauljiso4ie4

Integrated Physiology/Obesity

2011 Diabetes  
Interestingly, we found that HMEC cells started showing such changes after passage 1 in HG(compared to passage 4 in NG), whereas such changes were seen in HUVECs at passage 4 in HG(compared to passage  ...  ERCC1, ERCC4 mRNA expression was found to be decreased in HMEC but increased in HUVEC in earlier passages. Such changes were prevented by treatment with resveratrol.  ...  Sleeve gastrectomy is a newer obesity surgery that has similar weight loss in comparative studies, but the sleeve gastrectomy groups in those studies have all been 80 or less patients.  ... 
doi:10.2337/db11-1625-1928 fatcat:yna2gohzvfdhhaa6judaen2hba

2021 Western Medical Research Conference

2020 Journal of Investigative Medicine  
Conclusions We highlight a significant risk of epilepsy in NGLY1 deficiency and detail the clinical and electrographic features identified in our international cohort.  ...  Purpose of Study To refine the electroclinical phenotype of epilepsy in NGLY1 deficiency via prospective clinical and electroencephalogram (EEG) findings in an international cohort.  ...  We compared ADC values and T in thalamus, basal ganglia, parietal gray matter (pGM) and white matter (WM), and magnitude of ADC change between NM vs MS.  ... 
doi:10.1136/jim-2021-wrmc fatcat:ec52pfr2efgafb665m2czugyqy